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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5745 products of "GPCR/G-Protein"

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  • CymitQuimica logo
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    Cenderitide

    CAS:
    <p>Cenderitide fuses CNP with DNP, stimulates pGC-A/B, ups cGMP, curbs aldosterone, and aids GFR, not affecting BP—used in heart failure studies.</p>
    Formula:C158H263N49O50S3
    Color and Shape:Solid
    Molecular weight:3745.27

    Ref: TM-T76334

  • p-MPPF
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    p-MPPF

    CAS:
    <p>p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.</p>
    Formula:C25H27FN4O2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:434.51

    Ref: TM-T69750L

  • (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
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    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH

    CAS:
    <p>Analog of LHRH, stimulates LH and FSH release, controls reproduction.</p>
    Formula:C59H84N18O14
    Color and Shape:Solid
    Molecular weight:1269.41

    Ref: TM-T76616

  • Etelcalcetide
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    Etelcalcetide

    CAS:
    <p>Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.</p>
    Formula:C38H73N21O10S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1048.26

    Ref: TM-TP1235

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    Neuropeptide Y (2-36) (porcine)

    CAS:
    <p>Porcine Neuropeptide Y (2-36) is 97.14% similar to rat/human, an agonist for Y5, Y2, Y1 receptors, used in obesity research.</p>
    Formula:C181H278N54O55
    Color and Shape:Solid
    Molecular weight:4090.47

    Ref: TM-T76356

  • Proglumide hemicalcium
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    Proglumide hemicalcium

    CAS:
    Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.
    Formula:C18H28CaN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:376.51

    Ref: TM-T12544

  • (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
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    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)

    CAS:
    <p>(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a corticotropin-releasing factor (CRF) antagonist known to counteract the inhibitory effects of IL-1a</p>
    Formula:C159H267N49O43
    Color and Shape:Solid
    Molecular weight:3553.12

    Ref: TM-T76602

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    Pramlintide TFA

    Pramlintide TFA, a polypeptide analogue of human amylin and an antidiabetic agent, exhibits antineoplastic properties in colorectal cancer [1].
    Formula:C173H268N51F3O55S2
    Color and Shape:Solid
    Molecular weight:4063.4

    Ref: TM-T75709

  • QWF acetate
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    QWF acetate

    <p>QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.</p>
    Formula:C40H47N5O10
    Purity:96.65%
    Color and Shape:Solid
    Molecular weight:757.84

    Ref: TM-TP1946L

  • [Des-Arg9]-Bradykinin
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    [Des-Arg9]-Bradykinin

    CAS:
    <p>[Des-Arg9]-Bradykinin ([Des-Arg9]-Bradykinin(2TFA))(2TFA) is an agonist of Bradykinin (B1) receptor.</p>
    Formula:C44H61N11O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:904.02

    Ref: TM-T7645

  • Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
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    Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

    CAS:
    Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate is an NPR-A agonist and ANP hormone. Carperitide increases cGMP levels and reduces the heart's workload.
    Formula:C129H207N45O41S3
    Purity:99.78%
    Color and Shape:Soild
    Molecular weight:3140.5

    Ref: TM-TP1219

  • ACT-1016-0707
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    ACT-1016-0707

    CAS:
    <p>ACT-1016-0707 is a selective, insurmountable LPA1 antagonist with antifibrotic and anti-inflammatory activity in lung fibrosis models</p>
    Formula:C19H23ClN4O4S
    Purity:99.905%
    Color and Shape:Solid
    Molecular weight:438.93

    Ref: TM-T85589

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    sGC activator 2

    sGC activator 2 (Compound 16a) acts as an activator of soluble guanylate cyclase (sGC), enhancing the production of cGMP and exhibiting vasoprotective and anti-inflammatory properties.
    Formula:C21H21FN8O3
    Color and Shape:Solid
    Molecular weight:452.44

    Ref: TM-T203032

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    Urocortin III (human)

    CAS:
    <p>Urocortin III, a human peptide, binds CRF-R2, affecting insulin via somatostatin feedback with K i values 13.5-100+ nM.</p>
    Formula:C185H307N53O50S2
    Color and Shape:Solid
    Molecular weight:4137.93

    Ref: TM-T76180

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    (D-Ala2)-GRF (1-29) amide (human)

    CAS:
    (D-Ala2)-GRF (1-29) amide (human) is a potent superagonist of Growth Hormone-Releasing Factor (GRF), demonstrating an exceptionally high Growth Hormone (GH)-
    Formula:C149H246N44O42S
    Molecular weight:3357.88

    Ref: TM-T83549

  • 8-Chloro caffeine
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    8-Chloro caffeine

    CAS:
    <p>8-Chloro caffeine binds to adenosine receptors with a Ki of 30 µM. It enhances UV-induced chromosomal aberrations in the Cl-I type Chinese hamster embryo lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine.</p>
    Formula:C8H9ClN4O2
    Color and Shape:Solid
    Molecular weight:228.64

    Ref: TM-T203277

  • Methylhexanamine hydrochloride
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    Methylhexanamine hydrochloride

    CAS:
    Methylhexanamine hydrochloride is a fatty amine and vasoconstrictor that functions as a nasal decongestant when inhaled through the nasal mucosa.
    Formula:C7H18ClN
    Color and Shape:Solid
    Molecular weight:151.68

    Ref: TM-T203221

  • Orforglipron hemicalcium hydrate
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    Orforglipron hemicalcium hydrate

    CAS:
    Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) represents the hemicalcium hydrate form of the calcium salt of Orforglipron, an orally active agonist targeting the Glucagon-like peptide-1 receptor (GLP-1R). This compound has demonstrated efficacy in mitigating type 2 diabetes [1].
    Formula:C48H48F2N10O5Ca·H2O
    Color and Shape:Solid
    Molecular weight:921.02

    Ref: TM-T87071

  • Amylin (8-37), human
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    Amylin (8-37), human

    CAS:
    Human-derived Amylin (8-37) is a vasodilator in rat arteries and forms aggregates linked to type II diabetes.
    Formula:C138H216N42O45
    Color and Shape:Solid
    Molecular weight:3183.495

    Ref: TM-T38764

  • Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin
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    Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin

    CAS:
    Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), acts as a weak agonist at the antidiuretic receptor but is a potent
    Formula:C45H63N15O11S2
    Color and Shape:Solid
    Molecular weight:1054.21

    Ref: TM-T76509