GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 18 more subcategories

Found 5696 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

+ Info
P2Y6R antagonist 1
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active antagonist of P2Y6R, featuring an IC50 value of 19.6 nM. This compound also exhibits anti-inflammatory properties.
Color and Shape:Odour Solid
Ref: TM-T200515
+ Info
Atilmotin
CAS:
- 533927-56-9
Atilmotin is a gastrointestinal agent for treating motility disorders.
Formula:C₈₆H₁₃₅N₂₀O₁₉
Color and Shape:Solid
Molecular weight:1753.146
Ref: TM-T30199
+ Info
HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.
Color and Shape:Odour Solid
Ref: TM-T200554
+ Info
Obestatin(rat)
CAS:
- 869705-22-6
Endogenous peptide that suppresses food intake and body weight-gain
Formula:C₁₁₄H₁₇₄N₃₄O₃₁
Purity:98%
Color and Shape:Solid
Molecular weight:2516.81
Ref: TM-TP2279
+ Info
Adrenocorticotropic Hormone (ACTH) (1-39), rat
CAS:
- 77465-10-2
ACTH (1-39), rat: potent MC2 agonist, forms fragments in vitro, isolated by HPLC, characterized by amino acids and NH2-terminus.
Formula:C₂₁₀H₃₁₅N₅₇O₅₇S
Purity:98%
Color and Shape:Solid
Molecular weight:4582.23
Ref: TM-TP1249
+ Info
[Des-Arg9]-Bradykinin
CAS:
- 15958-92-6
[Des-Arg9]-Bradykinin ([Des-Arg9]-Bradykinin(2TFA))(2TFA) is an agonist of Bradykinin (B1) receptor.
Formula:C₄₄H₆₁N₁₁O₁₀
Purity:98%
Color and Shape:Solid
Molecular weight:904.02
Ref: TM-T7645
+ Info
Peptide YY (PYY), human
CAS:
- 118997-30-1
PYY: a 36-amino-acid hormone, amidated, part of neuroendocrine control, acts via Neuropeptide Y receptors.
Formula:C₁₉₄H₂₉₅N₅₅O₅₇
Purity:98%
Color and Shape:Solid
Molecular weight:4309.75
Ref: TM-TP1762
+ Info
CB1R agonist 1
CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.
Formula:C₂₀H₁₈F₃N₃O₃S
Color and Shape:Solid
Molecular weight:437.435
Ref: TM-T206337
+ Info
Cortistatin 14, human, rat acetate
Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and
Formula:C₈₀H₁₁₂N₁₈O₁₉S₂
Purity:97.86%
Color and Shape:Solid
Molecular weight:1693.98
Ref: TM-TP1188L
+ Info
Kisspeptin-54(human) TFA
Endogenous kisspeptin-54(human) TFA targets KISS1/GPR54 receptors; Ki: 1.81 nM (rat), 1.45 nM (human); inhibits metastasis, boosts gonadotropin.
Formula:C₂₅₈H₄₀₁N₇₉O₇₈·C₂HF₃O₂
Color and Shape:Solid
Molecular weight:5971.45
Ref: TM-T75774
+ Info
Bombinakinin M
CAS:
- 509151-65-9
Potent, selective bradykinin receptor agonist 50x stronger than bradykinin, contracts guinea pig ileum muscle at EC50 4.0 nM.
Formula:C₁₀₀H₁₅₉N₃₁O₂₄
Purity:98%
Color and Shape:Solid
Molecular weight:2179.55
Ref: TM-TP2075
+ Info
G-Protein antagonist peptide
CAS:
- 143675-79-0
Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.
Formula:C₅₇H₆₄N₁₂O₉S
Purity:98%
Color and Shape:Solid
Molecular weight:1093.27
Ref: TM-TP1902
+ Info
Preclamol hydrochloride
CAS:
- 88768-67-6
Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.
Formula:C₁₄H₂₂ClNO
Color and Shape:Solid
Molecular weight:255.78
Ref: TM-T73684
+ Info
5-HT2C agonist-4
CAS:
- 2730085-33-1
Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.
Formula:C₂₄H₂₅N₅O
Color and Shape:Solid
Molecular weight:399.49
Ref: TM-T203570
+ Info
[Des-Arg10]-HOE I40 TFA
[Des-Arg10]-HOE I40 TFA is a potent antagonist of the bradykinin B1 receptor.
Formula:C₅₃H₇₇N₁₅O₁₂S·xC₂HF₃O₂
Color and Shape:Solid
Ref: TM-T207446
+ Info
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin
CAS:
- 129520-65-6
Potent VP V1R antagonist, lowers rat MAP: '(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin'.
Formula:C₅₄H₇₆N₁₄O₁₁
Color and Shape:Solid
Molecular weight:1097.27
Ref: TM-T76633
+ Info
GRL018-21
GRL018-21 is a potent, highly selective inhibitor of G protein-coupled receptor kinase 5 (GRK5), exhibiting an IC50 of 10 nM [1].
Color and Shape:Odour Solid
Ref: TM-T82258
+ Info
MM 419447
CAS:
- 1092457-78-7
MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist showing potential in IBS-C research.
Formula:C₅₀H₇₀N₁₄O₁₉S₆
Color and Shape:Solid
Molecular weight:1363.55
Ref: TM-T38482
+ Info
INCB 3284 dimesylate
CAS:
- 887401-93-6
INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.
Formula:C₂₈H₃₉F₃N₄O₁₀S₂
Purity:98%
Color and Shape:Solid
Molecular weight:712.76
Ref: TM-T11647
+ Info
Imelciment
CAS:
- 2845128-03-0
Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.
Purity:95%
Color and Shape:Soild
Ref: TM-T9901A-366