GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,027 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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JNJ-5207787
CAS:JNJ-5207787, a blood-brain barrier-crossing Y2 receptor antagonist, is >100x selective against Y1/Y4/Y5 and inhibits human/rat Y2 with pIC50s of 7.0/7.1.Formula:C32H38N4O2Purity:98%Color and Shape:SolidMolecular weight:510.67GLP-1 receptor agonist 4
CAS:GLP-1 receptor agonist 4 targets GLP-1R, EC50 64.5 nM, potential diabetes treatment research.Formula:C51H44Cl2N4O6Purity:98%Color and Shape:SolidMolecular weight:879.82Vedaprofen
CAS:Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at IC50 222 μM, Ki 131 μM.Formula:C19H22O2Purity:99.24% - 99.70%Color and Shape:SolidMolecular weight:282.38Carbazochrome salicylate
CAS:Carbazochrome salicylate can be used as a coagulant.Formula:C17H18N4NaO6Color and Shape:White Crystalline PowderMolecular weight:397.34315(S)-HpEPE
CAS:15(S)-HpEPE, a monohydroperoxy fatty acid, forms when 15-lipoxygenase acts on EPA, with expected biological activities akin to 15(S)-HpETE.Formula:C20H30O4Color and Shape:SolidMolecular weight:334.456Alosetron-d3
CAS:Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.Formula:C17H18N4OPurity:98%Color and Shape:SolidMolecular weight:297.37RF9
CAS:RF9 is an effective and selective antagonist of the Neuropeptide FF receptor (Kis: 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively).Formula:C26H38N6O3Purity:98%Color and Shape:SolidMolecular weight:482.62GLP-1R agonist 15
CAS:GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .Formula:C46H47FN8O7SColor and Shape:SolidMolecular weight:874.98G-Protein antagonist peptide
CAS:Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.Formula:C57H64N12O9SPurity:98%Color and Shape:SolidMolecular weight:1093.27Cortagine
Potent CRF1 agonist, EC50 = 0.18 nM in rats. Exhibits in vivo anxiolytic and antidepressant effects; reduces mouse defensive behavior.Formula:C192H323N55O63SPurity:98%Color and Shape:SolidMolecular weight:4442.06β2AR/M-receptor agonist-1
CAS:β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor andFormula:C43H56BrN3O7Color and Shape:SolidMolecular weight:806.82Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.Formula:C22H26FN5OColor and Shape:SolidMolecular weight:395.472,3-dinor Thromboxane B1
CAS:TXB2 released from platelets becomes 11-dehydro and 2,3-dinor TXB2. Rats excrete 2,3-dinor TXB1, a reliable thromboxane biosynthesis marker.Formula:C18H32O6Color and Shape:SolidMolecular weight:344.448Prostaglandin F2α isopropyl ester
CAS:PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility.Formula:C23H40O5Color and Shape:SolidMolecular weight:396.568Alosetron
CAS:Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.Formula:C17H18N4OPurity:98%Color and Shape:Crystalline PowderMolecular weight:294.36Endothelin-2 (49-69), human TFA
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.Formula:C117H161N26F3O34S4Purity:98%Color and Shape:SolidMolecular weight:2660.94Lenbelintide
CAS:Lenbelintide is a dual amylin/calcitonin receptor agonist, useful in studies related to obesity.Color and Shape:SolidSamelisant
CAS:Samelisant (SUVN-G3031), a selective H3 inverse agonist, Ki=8.7/9.8 nM in humans/rats, has anti-narcoleptic properties.Formula:C21H31N3O3Purity:99.59%Color and Shape:SolidMolecular weight:373.49Ref: TM-T9770
1mg105.00€2mg158.00€5mg260.00€1mL*10mM (DMSO)268.00€10mg416.00€25mg687.00€50mg964.00€100mg1,288.00€500mg2,602.00€GRK2i
CAS:GRK2 inhibitory polypeptide that specifically inhibits Gβγ activation of GRK2. Corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist.Formula:C153H256N50O41SPurity:98%Color and Shape:SolidMolecular weight:3484.08CB1-IN-3
CB1-IN-3 (Compound 6i) is a potent inhibitor of the cannabinoid receptor type 1 (CB1). It holds potential for research in obesity, inflammation, and neurological disorders.Color and Shape:Odour Solid
