GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,025 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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8β-Hydroxy-exo-THC
CAS:8β-Hydroxy-exo-THC, a cannabinoid ether analog, exhibits weak affinity for receptor sites with an IC50 of 1.2 μM.Formula:C21H30O3Color and Shape:SolidMolecular weight:330.462,6-DMA hydrochloride
CAS:2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Formula:C11H18ClNO2Color and Shape:SolidMolecular weight:231.72Methylhexanamine hydrochloride
CAS:Methylhexanamine hydrochloride is a fatty amine and vasoconstrictor that functions as a nasal decongestant when inhaled through the nasal mucosa.Formula:C7H18ClNColor and Shape:SolidMolecular weight:151.688-Chloro caffeine
CAS:8-Chloro caffeine binds to adenosine receptors with a Ki of 30 µM. It enhances UV-induced chromosomal aberrations in the Cl-I type Chinese hamster embryo lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine.Formula:C8H9ClN4O2Color and Shape:SolidMolecular weight:228.64UKH-1114
CAS:UKH-1114 is a potent σ2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.Formula:C22H24F3NOColor and Shape:SolidMolecular weight:375.43sGC activator 2
sGC activator 2 (Compound 16a) acts as an activator of soluble guanylate cyclase (sGC), enhancing the production of cGMP and exhibiting vasoprotective and anti-inflammatory properties.Formula:C21H21FN8O3Color and Shape:SolidMolecular weight:452.44PACAP (1-38), human, ovine, rat TFA
PACAP (1-38), neuropeptide from bovine brain, surpasses VIP in adenylate cyclase activation (EC50=7 nM), alters peptide release, affects gastrin and motility.Formula:C203H331N63O53S·C2HF3O2Purity:98%Color and Shape:SolidMolecular weight:4648.28K41498
CAS:Potent CRF2α/β antagonist; Ki: 0.66/0.62 nM, weak for CRF1 (425 nM). Blocks sauvagine in hCRF2 cells and urocortin hypotension in rats.Formula:C162H276N48O46Purity:98%Color and Shape:SolidMolecular weight:3632.26QWF acetate
QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.
Formula:C40H47N5O10Purity:96.65%Color and Shape:SolidMolecular weight:757.84Adrenomedullin (AM) (22-52), human
CAS:Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.Formula:C159H252N46O48Purity:98%Color and Shape:SolidMolecular weight:3576.04HCGRP-(8-37)
CAS:Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFormula:C139H230N44O38Purity:98%Color and Shape:SolidMolecular weight:3125.59CYM5442 hydrochloride
CAS:CYM 5442 HCl: potent, selective S1P1 agonist (EC50 = 1.35 nM), induces MAPK activation & lymphopenia, brain-penetrant.Formula:C23H28ClN3O4Color and Shape:SolidMolecular weight:445.94TT-OAD2 free base
CAS:TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.Formula:C50H47Cl2N3O6Purity:98%Color and Shape:SolidMolecular weight:856.83Bombinakinin M acetate
Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and isFormula:C102H163N31O26Purity:99.80%Color and Shape:SolidMolecular weight:2239.58L-796,778
CAS:L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.Formula:C29H40N6O7Purity:99.24%Color and Shape:SolidMolecular weight:584.66Ref: TM-T32511
1mg175.00€5mg404.00€1mL*10mM (DMSO)522.00€10mg592.00€25mg888.00€50mg1,243.00€100mg1,701.00€500mg3,402.00€LCKLSL acetate
LCKLSL acetate is a potent AnxA2 inhibitor, blocking tPA binding and plasmin production, with anti-angiogenic effects.Formula:C32H61N7O10SPurity:99.9%Color and Shape:SolidMolecular weight:735.93CB2R/FAAH modulator-2
CAS:CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.Formula:C24H33NO2Purity:99.15%Color and Shape:SoildMolecular weight:367.52Des His1, Glu8 Exendin-4
Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.Formula:C179H277N47O59SPurity:99.92%Color and Shape:SolidMolecular weight:4063.46[D-Trp34]-Neuropeptide Y Acetate
[D-Trp34]-Neuropeptide Y Acetate is a potent Y5 receptor agonist that increases rat food intake; less potent at Y1, Y2, Y4, Y6.Formula:C198H293N55O58Purity:99.73%Color and Shape:SoildMolecular weight:4371.78Galanin (1-15) (porcine, rat)
CAS:N-terminal galanin fragment used to mediate central cardiovascular effectsFormula:C72H105N19O20Purity:98%Color and Shape:SolidMolecular weight:1556.72
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