GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,022 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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BE-24566B
CAS:BE-24566B, a polyketide from S. violaceusniger, inhibits various bacteria and blocks ET receptors (ETA IC50=11 μM, ETB=3.9 μM).Formula:C27H24O7Color and Shape:SolidMolecular weight:460.482CCR6 antagonist 2
CCR6 antagonist2 (Compound 20c) acts as a CCR6 antagonist with a Ki of 1.1 nM. It inhibits CCL20-induced calcium influx with an IC50 of 4.9 nM and suppresses the chemotactic migration of CCR6+ T cells with an IC50 of 190 nM.Formula:C19H24N4O4Color and Shape:SolidMolecular weight:372.42GIP/GLP-1 dual receptor agonist-1 sodium
GIP/GLP-1 dual receptor agonist-1 (Compound 4) (sodium) functions as a GIP/GLP-1 receptor agonist. This compound is applicable for research into metabolic disorders and liver diseases, including non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD).Color and Shape:Odour Solidmeta-Fluoxetine (hydrochloride)
CAS:meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formula:C17H19ClF3NOColor and Shape:SolidMolecular weight:345.793-hydroxy Desloratidine
CAS:3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.Formula:C19H19ClN2OColor and Shape:SolidMolecular weight:326.82Glucagon Receptor Antagonist Inactive Control
CAS:Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences.Formula:C21H23BrN2OSColor and Shape:SolidMolecular weight:431.39Astressin
CAS:Astressin is a truncated CRF analog; binds strongly to receptor's extracellular domain, likely acting as a neutral competitive antagonist.Formula:C161H269N49O42Purity:98%Color and Shape:SolidMolecular weight:3563.16ALD1910
ALD1910 is a humanized monoclonal antibody targeting PACAP38 and PACAP27. It inhibits PACAP signaling through pituitary adenylate cyclase-activating peptide type I receptor (PAC1-R), vasoactive intestinal peptide receptor 1 (VPAC1-R), and VPAC2-R. ALD1910 recognizes a non-linear epitope within PACAP and prevents its binding to cell surfaces. It is useful for studying PACAP-mediated migraines.Color and Shape:Odour Liquid[Gly8]-GLP-1(7-37) acetate
[Gly8]-GLP-1(7-37) acetate is a derivative of GLP-1, where glycine at position 8 is replaced with alanine. [Gly8]-GLP-1(7-37) acetate is also a peptide fragment of the GLP-1 receptor (GLP-1R) agonist, Dulaglutide.Color and Shape:Odour SolidSelank
CAS:Selank is a synthetic analog of tuftsin.Formula:C33H57N11O9Purity:98%Color and Shape:SolidMolecular weight:751.87Ethoxyquin Dimer
CAS:Ethoxyquin dimer is an antioxidant, metabolite of ethoxyquin, that protects fish meal/oil fats but can cause liver damage in mice.Formula:C28H36N2O2Color and Shape:SolidMolecular weight:432.608Filimelnotide
CAS:Filimelnotide is an agonist of the melanocortin receptor.Formula:C47H69N15O9S2Color and Shape:SolidMolecular weight:1052.28HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65L803
CAS:L803 is a selective somatostatin receptor type 4 (SST4) agonist that can inhibit L-type calcium channel currents (ICa). It holds potential for research into degenerative diseases of retinal ganglion cells (RGC), such as glaucoma.Formula:C50H80N13O19PColor and Shape:SolidMolecular weight:1198.22CMKLR1 antagonist 1
CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-Color and Shape:Odour SolidMoxilubant HCl
CAS:Moxilubant HCl: small molecule LTB4R antagonist for immune, skin, musculoskeletal disorders, and research in psoriasis, arthritis.Formula:C26H38ClN3O4Purity:99.94%Color and Shape:SoildMolecular weight:492.05L-703606 oxalate hydrate
L-703606 oxalate hydrate is an effective, selective NK1 receptor antagonist. It is utilized in research related to gastric acid secretion.Color and Shape:Odour Solid9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
CAS:Meteneprost is a strong, long-lasting Prostaglandin E2 analog effective in ending early monkey pregnancies without causing fever or GI issues.Formula:C23H38O4Color and Shape:SolidMolecular weight:378.553NN1213
NN1213 (Peptide 21) is a long-acting human amylin peptide analogue that functions as a selective amylin receptor agonist. It has an EC50 of 0.177 nM for hAMY3R and 0.262 nM for rAMY3R. In both rat and dog models, NN1213 significantly reduces appetite and is utilized in anti-obesity research.Color and Shape:Odour SolidYM 218
CAS:YM 218 is a novel, potent, selective antagonist of nonpeptide vasopressin V1A receptor.Formula:C35H38F2N4O4Color and Shape:SolidMolecular weight:616.7
