GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,997 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(40 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5958 products of "GPCR/G-Protein"
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Norisoboldine hydrochloride
CAS:Norisoboldine hydrochloride: an oral AhR agonist from Radix Linderae, for Rheumatoid arthritis and Ulcerative colitis research.Formula:C18H20ClNO4Color and Shape:SolidMolecular weight:349.81[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
CAS:[Tyr22] CGRP (22-37), rat is a fragment of rat CGRP, targeting its receptor and adenylate cyclase, produced by thyroid and stored in the nervous system.Formula:C82H120N20O25Color and Shape:SolidMolecular weight:1785.95Pemvidutide TFA
Pemvidutide (TFA), a GLP-1R/GCGR dual agonist, effectively reduces body weight, liver fat, and serum lipid levels, and is utilized in research on non-alcoholicFormula:C182H275N39O54·xC2HF3O2Color and Shape:SolidMolecular weight:3873.35 (free base)15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
CAS:Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which hasFormula:C25H35NO4Color and Shape:SolidMolecular weight:413.558Phendioxan
CAS:Phendioxan is a biochemcial.Formula:C25H27NO5Color and Shape:SolidMolecular weight:421.49CIA-1 (Free base)
CAS:CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Formula:C17H19N3O2SPurity:99%Color and Shape:SolidMolecular weight:329.42PZ-128
CAS:PZ-128, a PAR1 antagonist, is used potentially for the treatment of thrombosis.Formula:C55H99N13O9Purity:98%Color and Shape:SolidMolecular weight:1086.46Nesiritide acetate
CAS:Nesiritide, a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide, enhances vasorelaxation ex vivo in porcine hearts from an acute coronary occlusion model when given as a 2 µg/kg bolus dose followed by a 0.01 µg/kg per minute infusion, facilitated by the calcium ionophore A23187. Formulations containing nesiritide have been utilized in managing congestive heart failure.Formula:C143H244N50O42S4C2H4O2Color and Shape:SolidMolecular weight:3524.1N-desmethyl Zolmitriptan
CAS:DZT, an active metabolite of zolmitriptan, agonizes 5-HT1B/D receptors; contracts human cerebral arteries (EC50=100nM).Formula:C15H19N3O2Color and Shape:SolidMolecular weight:273.332,3-dinor Thromboxane B1
CAS:TXB2 released from platelets becomes 11-dehydro and 2,3-dinor TXB2. Rats excrete 2,3-dinor TXB1, a reliable thromboxane biosynthesis marker.Formula:C18H32O6Color and Shape:SolidMolecular weight:344.448SR 142948 TFA
SR 142948 TFA is an orally active, selective non-peptide neurotensin receptor (NT) antagonist, displaying IC50 values of 1.19 nM in h-NTR1-CHO cells, 0.32 nM in HT-29 cells, and 3.96 nM in adult rat brain. In HT-29 cells, it counteracts NT-induced inositol monophosphate formation with an IC50 of 3.9 nM. It blocks NT-induced hypothermia, analgesia, and turning behavior in vivo and can cross the blood-brain barrier, making it useful for research in psychiatric disorders.Color and Shape:Odour SolidCanine KP-10
Canine KP-10 is a potent kisspeptin that induces a significant gonadotropin and estradiol response in female dogs during estrus.Color and Shape:Odour SolidZevaquenabant
CAS:Zevaquenabant (S-MRI-1867): oral CB1/iNOS antagonist combatting obesity-induced CKD.Formula:C25H21ClF3N5O2SColor and Shape:SolidMolecular weight:547.98CCK (26-31) (non-sulfated)
CAS:CCK (26-31) is a digestive, satiety-inducing, anxiety-related peptide fragment from CCK hormone in the brain and gut.Formula:C38H50N8O10S2Color and Shape:SolidMolecular weight:842.98HGS101
HGS101 is a fully humanized CCR5 monoclonal antibody that exhibits high affinity for CCR5. It binds to the second extracellular loop (ECL-2) and functions as a signaling antagonist. HGS101 restores the inhibitory effect of Maraviroc in Maraviroc-resistant HIV-1 infected PBMCs. In an uninfected simian immunodeficiency virus model of rhesus monkeys, HGS101 shows anti-HIV activity by inhibiting CCR5 signaling.Color and Shape:Odour LiquidElabela(19-32)
CAS:APJ receptor agonist with Ki of 0.93 nM, derived from ELA-32, activates Gαi1, β-arrestin-2, lowers rat heart arterial pressure, effective in vivo.Formula:C75H119N25O17S2Purity:98%Color and Shape:SolidMolecular weight:1707.03LP-20
CAS:LP-20 is a bioactive chemical.Formula:C17H20N2OColor and Shape:SolidMolecular weight:268.35Prostaglandin F2α methyl ester
CAS:Prostaglandin F2α methyl ester is a highly lipid-soluble PGF2α analog used to maintain low intraocular pressure.Formula:C21H36O5Color and Shape:SolidMolecular weight:368.51Methimepip dihydrobromide
CAS:Methimepip dihydrobromide is a selective H3R agonist.Formula:C10H19Br2N3Color and Shape:SolidMolecular weight:341.091Biotin-Gastrin Releasing Peptide, human TFA
Biotin-Gastrin Releasing Peptide, human TFA, is a biotinylated form of the gastrin-releasing peptide (GRP). GRP is a neuropeptide known for its growth-stimulating and tumorigenic properties.Color and Shape:Odour Solid
![[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76363.webp&w=3840&q=75)
