
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(993 products)
- Adenosine Receptor(246 products)
- Adrenergic Receptor(3,004 products)
- Bombesin Receptor(33 products)
- Bradykinin Receptor(59 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(212 products)
- Dopamine Receptor(433 products)
- Endothelin Receptor(79 products)
- GNRH Receptor(77 products)
- GPCR19(32 products)
- GRK(32 products)
- GTPase(22 products)
- Glucagon Receptor(182 products)
- Hedgehog/Smoothened(47 products)
- Histamine Receptor(381 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(310 products)
- PAFR(12 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5745 products of "GPCR/G-Protein"
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Butopamine
CAS:Butopamine differs from dobutamine in location of only one hydroxyl group, but is no longer a catecholamine.Formula:C18H23NO3Color and Shape:SolidMolecular weight:301.38Methiothepin maleate
CAS:<p>Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.</p>Formula:C24H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:472.625-OxoETE methyl ester
CAS:5-OxoETE methyl ester is a 5-oxoETE ester, an OXER1 agonist with stronger β-arrestin response, EC50 = 1.54 μM.Formula:C21H32O3Color and Shape:SolidMolecular weight:332.48JNJ-10191584
CAS:JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammationFormula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.74Guanfacine
CAS:Guanfacine is a selective agonist of the α2A receptor.Formula:C9H9Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:246.09PF 10040
CAS:PF 10040 is an antagonist of platelet activating factor (PAF).Formula:C20H24ClNO2Color and Shape:SolidMolecular weight:345.86Noberastine maleate
CAS:Noberastine maleate, a fast-acting furan-derived H1 antagonist, peaks at 4 hours with minimal CNS effects and maximal efficacy at 30 mg/day.Formula:C25H29N5O9Color and Shape:SolidMolecular weight:543.53SC 51089 free base
CAS:<p>SC 51089 free base is a selective antagonist of the prostaglandin E2 EP1 receptor, demonstrating neuroprotective activity.</p>Formula:C22H19ClN4O3Color and Shape:SolidMolecular weight:422.866-Chloromelatonin
CAS:6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.Formula:C13H15ClN2O2Purity:97.26% - 99.25%Color and Shape:SolidMolecular weight:266.72PD 144418
CAS:PD 144418 displays potential antipsychotic activity.Formula:C18H22N2OPurity:98%Color and Shape:SolidMolecular weight:282.38Metrenperone
CAS:Metrenperone is used as a S(2)-receptor blocker.Formula:C24H26FN3O2Purity:98%Color and Shape:SolidMolecular weight:407.48Seliforant
CAS:Seliforant is a histamine H4 receptor antagonist.Formula:C12H21N5Purity:98%Color and Shape:SolidMolecular weight:235.33Bucumarol (HCl)
CAS:Bucumarol is a beta-adrenergic blocking agent.Formula:C17H24ClNO4Color and Shape:SolidMolecular weight:341.83Oxypertine
CAS:Oxypertine, an indole-derived antipsychotic, treats psychoses like mania, schizophrenia, and severe anxiety, akin to chlorpromazine.Formula:C23H29N3O2Color and Shape:SolidMolecular weight:379.5YM-17690
CAS:YM-17690 is a non-analogous leukotriene agonist.Formula:C28H29NO7Purity:98%Color and Shape:SolidMolecular weight:491.53CP-226269
CAS:<p>CP-226269 is a potent dopamine D4 receptor agonist that regulates calcium flux and has an EC50 value of 32.0 nM.</p>Formula:C18H19FN4Purity:99.08%Color and Shape:SolidMolecular weight:310.37Arbutamine
CAS:<p>Arbutamine (GP 21213) is a β-adrenoceptor agonist with alpha-1-sympathomimetic activity that can be used to study cardiac stress.</p>Formula:C18H23NO4Purity:95.06%Color and Shape:SolidMolecular weight:317.382-CMDO
CAS:2-CMDO is a Dopamine D2-like receptor antagonist.Formula:C23H23ClN2O5Purity:98%Color and Shape:SolidMolecular weight:442.89Anitrazafen
CAS:Anitrazafen is a locally effective anti-inflammatory agent that has been shown to have COX-2 inhibitor activity.Formula:C18H17N3O2Purity:98%Color and Shape:SolidMolecular weight:307.35ASP1126
CAS:ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist (EC50s: 7.12 nM, 517 nM for hS1P1 and hS1P3).Formula:C26H26ClF6NO5Purity:98%Color and Shape:SolidMolecular weight:581.93Way 100135
CAS:WAY-100135: research drug, phenylpiperazine, potent 5-HT1A antagonist, partial 5-HT1D agonist, minor 5-HT1B activity.Formula:C24H33N3O2Color and Shape:SolidMolecular weight:395.54Lusaperidone
CAS:Kaerophyllin ( (-)-Kaerophylin) inhibits hepatic stellate cell activation and inhibits HSC activation to protect against liver cell damage and fibrosis in rats.Formula:C22H21N3O2Purity:99.75%Color and Shape:SolidMolecular weight:359.42CCX777
CAS:<p>CCX777 is a partial agonist recruited to ACKR3 by β-arrestin-2 and is used in cancer research.</p>Formula:C31H43N7O3SPurity:98.73%Color and Shape:SolidMolecular weight:593.78A 987306
CAS:<p>A-987306: Potent, oral histamine H4 antagonist; Ki: 3.4 nM (rat), 5.8 nM (human); reduces inflammation in mouse peritonitis.</p>Formula:C18H25N5OColor and Shape:SolidMolecular weight:327.42SCH-23390 maleate
CAS:SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM,Formula:C21H22ClNO5Purity:98%Color and Shape:SolidMolecular weight:403.86CCR1 antagonist 7
CAS:<p>CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].</p>Formula:C21H24ClN5O3SPurity:98%Color and Shape:SolidMolecular weight:461.96WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Formula:C24H25NO10SPurity:98%Color and Shape:SolidMolecular weight:519.52L-365260
CAS:L-365260 is a nonpeptide gastrin and cerebral cholecystokinin receptor (CCK-B) antagonist used in the study of neurologic ojibwa and endocrine diseases.Formula:C24H22N4O2Purity:99.75%Color and Shape:SolidMolecular weight:398.46ADRA1D receptor antagonist 1 free base
CAS:ADRA1D antagonist blocks bladder contractions; Ki=1.6 nM, IC30=15 nM, useful in overactive bladder research.Formula:C15H13ClN4OColor and Shape:SolidMolecular weight:300.74DS-3801b
CAS:<p>DS-3801b is a non-macrolide GPR38 agonist with an N-methylaniline structure for the study of functional gastrointestinal disorders.</p>Formula:C28H39N3O3Purity:99.21%Color and Shape:SolidMolecular weight:465.632-Methylthioadenosine diphosphate trisodium
CAS:2-Methylthioadenosine diphosphate trisodium(2-MeS-ADP) is a purinergic P2Y receptor agonist that agonizes P2Y13 and P2Y12, induces platelet aggregation.Formula:C11H14N5Na3O10P2SColor and Shape:SolidMolecular weight:539.24PNU-177864
CAS:<p>PNU-177864 is a selective dopamine D3 receptor antagonist.</p>Formula:C18H21F3N2O3SPurity:99.92%Color and Shape:SolidMolecular weight:402.43S 14506 hydrochloride
CAS:<p>S 14506 hydrochloride is a 5-HT1A receptor full agonist.</p>Formula:C24H27ClFN3O2Purity:99.92%Color and Shape:SolidMolecular weight:443.94(R)-SLV 319
CAS:(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.Formula:C23H20Cl2N4O2SColor and Shape:SolidMolecular weight:487.4VNA-932
CAS:<p>VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay).</p>Formula:C23H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:402.88PF-03654746 Tosylate
CAS:<p>PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.</p>Formula:C25H32F2N2O4SPurity:98%Color and Shape:SolidMolecular weight:494.6SB-277011 dihydrochloride
CAS:<p>SB-277011 dihydrochloride: potent, selective D3 antagonist; orally bioavailable; crosses blood-brain barrier; pKi 8.0 for D3 receptor.</p>Formula:C28H32Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:511.495-HT3 antagonist 3
CAS:<p>5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).</p>Formula:C20H21N3OPurity:99.9%Color and Shape:SolidMolecular weight:319.4GALNON
CAS:<p>Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties</p>Formula:C40H46N4O6Purity:98%Color and Shape:SolidMolecular weight:678.82GBR 13069 dihydrochloride
CAS:GBR 13069 dihydrochloride is a dopamine uptake inhibitor.Formula:C28H32Cl2F2N2OPurity:98%Color and Shape:SolidMolecular weight:521.47Sigma-LIGAND-1
CAS:<p>Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively.</p>Formula:C27H33NO4Purity:99.89%Color and Shape:SolidMolecular weight:435.56Taprenepag isopropyl
CAS:Taprenepag isopropyl is a highly selective agonist of the EP2 receptor.Formula:C27H28N4O5SPurity:99.44%Color and Shape:SolidMolecular weight:520.65-HT6/5-HT2A receptor ligand-1
CAS:<p>Compound 33 is a dual 5-HT6/5-HT2A antagonist with Ki values of 2 nM and 11 nM, respectively, useful in neuro/psychiatric research.</p>Formula:C21H19FN2O2Color and Shape:SolidMolecular weight:350.39LRH-1 Inhibitor-3
CAS:LRH-1 Inhibitor-3 is an antagonist that inhibits LRH-1 transcriptional activity, reducing SHP, cyclin E1 (CCNE1), and G0S2,antiproliferation anticancer.Formula:C23H25N3O2Purity:98%Color and Shape:SolidMolecular weight:375.46PPTN
CAS:PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity.Formula:C29H24F3NO2Purity:99.86%Color and Shape:SolidMolecular weight:475.5Isamoltane hemifumarate
CAS:5-HT1B antagonistFormula:C16H22N202C4H404Purity:98%Color and Shape:SolidMolecular weight:332.4SB-221284
CAS:5-HT2C/2B receptor antagonistFormula:C16H14F3N3OSPurity:98%Color and Shape:SolidMolecular weight:353.36MRS2179
CAS:MRS2179: P2Y1 antagonist, Kb=100 nM, inactive on P2Y2/4/6 (to 30µM), inhibits ADP-induced platelet changes, prolongs bleeding in rodents.Formula:C11H17N5O9P2Color and Shape:SolidMolecular weight:425.23PD-89211
CAS:PD 89211 selectively blocks dopamine D4.2 receptor >800x vs. other subtypes; reverses quinpirole effect in vitro (IC50 = 2.1 nM).Formula:C19H21ClN4OPurity:98%Color and Shape:SolidMolecular weight:356.85CI 1020
CAS:endothelin-A receptor (ETA) antagonistFormula:C28H26O9Purity:98%Color and Shape:SolidMolecular weight:506.5BPIPP
CAS:guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitorFormula:C22H16BrN3O3Purity:98%Color and Shape:SolidMolecular weight:450.28Fonazine
CAS:Forazine (dimethiazide) is a phenothiazine drug used in the treatment of migraine and is a serotonin antagonist and a histamine antagonist.Formula:C19H25N3O2S2Color and Shape:SolidMolecular weight:391.55S-22153
CAS:<p>S22153 is an antagonist of melatonin receptor.</p>Formula:C14H17NOSColor and Shape:SolidMolecular weight:247.36Idremcinal
CAS:<p>Idremcinal is a motilin receptor agonist.</p>Formula:C39H69NO12Color and Shape:SolidMolecular weight:743.96CCG-273463
CAS:<p>CCG-273463: Potent GRK5 inhibitor (IC50: 9 nM), used for researching heart failure, hypertrophy, cancer.</p>Formula:C26H25BrN4O3Color and Shape:SolidMolecular weight:521.41MHP 133
CAS:<p>MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).</p>Formula:C17H20ClN5O3Purity:98%Color and Shape:SolidMolecular weight:377.83GR 128107
CAS:GR 128107 is an antagonist of melatonin receptor.Formula:C16H20N2O2Color and Shape:SolidMolecular weight:272.34HAMI 3379
CAS:HAMI 3379 (HAMI3379) is a CysLT2 antagonist that attenuates brain damage and inhibits microglia inflammation following focal cerebral ischemia in rats.Formula:C34H45NO8Purity:99.75%Color and Shape:SolidMolecular weight:595.72LY 125180
CAS:LY 125180 is a serotonin antagonist.Formula:C18H24ClNOPurity:98%Color and Shape:SolidMolecular weight:305.84(E)-Guanabenz
CAS:<p>(E)-Guanabenz is an oral α2-adrenoceptor agonist, antihypertensive, GADD34 inhibitor, and has neuroprotective properties.</p>Formula:C8H8Cl2N4Color and Shape:SolidMolecular weight:231.08Adenosine receptor A1 antagonist 5
CAS:<p>1,3-Dipropyl-8-phenylxanthine is an adenosine antagonist, oxypurine, insecticide, and reduces high blood pressure.</p>Formula:C17H20N4O2Purity:99.97%Color and Shape:SolidMolecular weight:312.37BIIL-260 hydrochloride
CAS:BIIL-260 hydrochloride is an LTB4 antagonist with anti-inflammatory activity, inhibiting LTB(4)-induced intracellular Ca(2+) release in human neutrophils.Formula:C30H31ClN2O3Purity:98.89%Color and Shape:SolidMolecular weight:503.03Benzamide Derivative 1
CAS:Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.Formula:C22H34ClN3O3Purity:>99.99%Color and Shape:SolidMolecular weight:423.98Clenproperol
CAS:Clenproperol is a β2-adrenergic agonist.Formula:C11H16Cl2N2OColor and Shape:SolidMolecular weight:263.16PF-04628935
CAS:PF-04628935: potent GHS-R1a antagonist/inverse agonist, IC50=4.6 nM, orally bioavailable, brain penetrant.Formula:C24H26ClN7OSPurity:98%Color and Shape:SolidMolecular weight:496.03B 4148
CAS:B 4148 is a bradykinin inhibitor.Formula:C62H95N19O14S2Color and Shape:SolidMolecular weight:1394.67Ipsapirone
CAS:<p>Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.</p>Formula:C19H23N5O3SPurity:99.51%Color and Shape:SolidMolecular weight:401.48Fenmetozole
CAS:Fenmetozole is an antagonist of the actions of ethanol.Formula:C10H10Cl2N2OColor and Shape:SolidMolecular weight:245.11PD-156707
CAS:PD-156707 is a selective antagonist of endothelin A receptor.Formula:C28H26NaO9Purity:98%Color and Shape:SolidMolecular weight:529.497OUP-186
CAS:OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.Formula:C19H30ClN3SColor and Shape:SolidMolecular weight:367.98NSC12404
CAS:<p>NSC-12404 is a selective non-lipid LPA2/3 agonist.</p>Formula:C21H13NO4Color and Shape:SolidMolecular weight:343.33ASP7657
CAS:ASP7657 is a novel, potent, and selective prostaglandin EP4 receptor antagonist.Formula:C28H26F3N3O3Color and Shape:SolidMolecular weight:509.52SDZ NKT 343
CAS:<p>human tachykinin NK1 receptor antagonist</p>Formula:C33H33N5O5Purity:98%Color and Shape:SolidMolecular weight:579.65Octoclothepin maleate salt
CAS:Octoclothepin maleate salt is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist.Formula:C23H25ClN2O4SColor and Shape:SolidMolecular weight:460.97MLN3126
CAS:MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.Formula:C21H19ClN2O5SColor and Shape:SolidMolecular weight:446.9OPC-14523 free base
CAS:OPC-14523, a 5-HT1A receptor agonist, is used potentially for the treatment of depression and neuropathic pain.Formula:C23H28ClN3O2Purity:98%Color and Shape:SolidMolecular weight:413.94(2R,3R)-E1R
CAS:(2R,3R)-E1R is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders.Formula:C13H16N2O2Purity:98%Color and Shape:SolidMolecular weight:232.28Prostaglandin D2
CAS:<p>Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.</p>Formula:C20H32O5Purity:>99.99%Color and Shape:SolidMolecular weight:352.47ICI 192605
CAS:ICI 192605 is a potent thromboxane A2 receptor (TP receptor) antagonist.Formula:C22H23ClO5Color and Shape:SolidMolecular weight:402.87AL-3138
CAS:<p>AL-3138 is a prostaglandin F2alpha (PGF2alpha) analogue which antagonizes FP prostanoid receptor-mediated inositol phosphates generation.</p>Formula:C20H33FO4Color and Shape:SolidMolecular weight:356.47SB-226552
CAS:SB-226552 is an aryloxypropanolamine selective beta3AR agonist.Formula:C25H36NO5PColor and Shape:SolidMolecular weight:461.53KSCM-1
CAS:KSCM-1 is a selective sigma-1 receptor ligand.Formula:C26H32N2O4Color and Shape:SolidMolecular weight:436.54I-SAP
CAS:<p>I-SAP: TP receptor blocker, alters platelet shape without causing clumping, EC50 9.7 nM, max binding pH 6.5-7.4, Kd 468-490 pM.</p>Formula:C22H30INO4SColor and Shape:SolidMolecular weight:531.45CCR8 antagonist 2
CAS:CCR8 antagonist 2 blocks CCR8 activity, mainly on Treg and Th2 cells, for treating related diseases. See WO2022000443A1, compound 220.Formula:C23H30ClN3O3SColor and Shape:SolidMolecular weight:464.02Bopindolol fumarate
CAS:<p>Bopindolol fumarate: non-selective β1/β2-adrenoceptor blocker, partial agonist, low β3 affinity, treats hypertension.</p>Formula:C27H32N2O7Color and Shape:SolidMolecular weight:496.56LY 344864 S-enantiomer
CAS:LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42Zinterol
CAS:<p>Zinterol is a potent and selective agonist of β2-adrenoceptor. Zinterol increases ICa in a concentration-dependent manner(EC50 of 2.2 nM).</p>Formula:C19H26N2O4SPurity:98%Color and Shape:SolidMolecular weight:378.49Lintopride
CAS:Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.Formula:C14H19ClN4O2Purity:98%Color and Shape:SolidMolecular weight:310.78AB-MECA
CAS:AB-MECA is a high affinity A3 adenosine receptor agonist. It has high affinity for recombinant A1 and A3 receptors.Formula:C18H21N7O4Purity:98%Color and Shape:SolidMolecular weight:399.4MK-8133
CAS:<p>MK-8133 is an antagonist of orexin-2 selective receptor with favorable development properties.</p>Formula:C23H21N5O2Color and Shape:SolidMolecular weight:399.45Methyldopate hydrochloride
CAS:Methyldopate HCl is an agent of antihypertensive.Formula:C12H18ClNO4Color and Shape:SolidMolecular weight:275.73A1/A3 AR antagonist 2
CAS:The compound is an a1/a3 adenosine receptor antagonist, which helps to treat (neurological) inflammatory diseases.Formula:C22H16N2O3SColor and Shape:SolidMolecular weight:388.44Alclofenac lysinate
CAS:Alclofenac is an anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also used as an analgesic and an antipyretic.Formula:C17H25ClN2O5Purity:98%Color and Shape:SolidMolecular weight:372.84R(+)-6-Bromo-APB HBr
CAS:R(+)-6-Bromo-APB HBr is used as a D1 Dopamine receptor agonist.Formula:C19H21Br2NO2Purity:98%Color and Shape:SolidMolecular weight:455.18A-943931
CAS:A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.Formula:C17H21N5Purity:99.79%Color and Shape:SolidMolecular weight:295.38BRL 37344 sodium
CAS:BRL 37344 sodium is a specific agonist of the β3-adrenergic receptor. The treatment of BRL 37344 sodium significantly lowers the bodyweight of obese mice.Formula:C19H22ClNNaO4Purity:98%Color and Shape:SolidMolecular weight:386.83(Rac)-HAMI 3379
CAS:HAMI 3379: potent CysLT2 receptor blocker; protects against acute/subacute brain injury; reduces microglia inflammation.Formula:C34H45NO8Purity:98%Color and Shape:SolidMolecular weight:595.72GR-55562 dihydrobromide
CAS:GR-55562 dihydrobromide is a antagonist of 5-HT1B/5-HT1D serotonin receptor.Formula:C23H26ClN3O2Purity:98%Color and Shape:SolidMolecular weight:411.93Quinelorane dihydrochloride
CAS:Dopamine D2 and D3 receptor agonistFormula:C14H23ClN4Purity:98%Color and Shape:SolidMolecular weight:282.81QCC-374
CAS:QCC-374 is a prostanoid agonist. It potentially for the treatment of pulmonary arterial hypertension.Formula:C28H33N3O2Purity:98%Color and Shape:SolidMolecular weight:443.58UK 1745
CAS:UK 1745 is a novel drug of cardiotonic.Formula:C16H23ClN2O2Color and Shape:SolidMolecular weight:310.82Zenidolol
CAS:Zenidolol (ICI-118551) is a β2 adrenoceptor blocker with K i values: β2 (0.7 nM), β1 (49.5 nM), β3 (611 nM); used in eye disease research.Formula:C17H27NO2Color and Shape:SolidMolecular weight:277.4CP-195543
CAS:CP-195543 is an effective leukotriene B4 antagonist for the treatment of inflammatory diseases.Formula:C24H19F3O4Color and Shape:SolidMolecular weight:428.4BAY-27-9955
CAS:BAY-27-9955 is a glucagon receptor antagonist.Formula:C23H31FOColor and Shape:SolidMolecular weight:342.49LY288513
CAS:Selective CCK2 receptor antagonistFormula:C22H18BrN3O2Purity:98%Color and Shape:SolidMolecular weight:436.3U-101958 Maleate
CAS:U-101958 Maleate binds to dopamine D4 and sigma1 receptors with high affinity in neuroblastoma cells and human cerebellum.Formula:C25H33N3O5Purity:98%Color and Shape:SolidMolecular weight:455.55GSK-269984B
CAS:GSK-269984B is a novel antagonist of EP1 receptor.Formula:C20H14Cl2FNO3Purity:98%Color and Shape:SolidMolecular weight:406.23Guanethidine
CAS:Guanethidine sulphate, made in 1959, lowers blood pressure by disrupting neurotransmitters in sympathetic nerves.Formula:C10H22N4Color and Shape:SolidMolecular weight:198.31EP4 receptor antagonist 4
CAS:EP4 receptor antagonist 4 is an agonist of EP4 receptor (human pEC 50 = 6.3) [1].Formula:C19H14N2OSColor and Shape:SolidMolecular weight:318.39SKF 83959 hydrobromide
CAS:SKF 83959 hydrobromide is a Dopamine D1-like receptor partial agonist.Formula:C18H21BrClNO2Purity:98%Color and Shape:SolidMolecular weight:398.72UCM 707
CAS:endocannabinoid transport inhibitorFormula:C25H37NO2Purity:98%Color and Shape:SolidMolecular weight:383.57SKF-75670 Hydrobromide
CAS:SKF-75670 hydrobromide is an atypical D1DR (dopamine receptor) agonist. It displays agonist activity in vivo and antagonist activity in vitro.Formula:C17H20BrNO2Color and Shape:SolidMolecular weight:350.25Zicronapine
CAS:Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.Formula:C22H27ClN2Color and Shape:SolidMolecular weight:354.92(+)-UH 232 maleate
CAS:D2 antagonistFormula:C18H29NOPurity:98%Color and Shape:SolidMolecular weight:275.43A 55453
CAS:A 55453 is a radiated ionophore used as a reversibl, high-affinity alpha 1-adrenergic receptor probe.Formula:C25H32N6O3Color and Shape:SolidMolecular weight:464.56Cirazoline hydrochloride
CAS:Cirazoline hydrochloride is a synthetic competitive full agonist of α1A-AR (Ki 120 nM) and partial agonist at α1B-AR and α1D-AR.Formula:C13H17ClN2OPurity:99.863%Color and Shape:SolidMolecular weight:252.74FRG8701
CAS:FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.Formula:C22H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:418.55CP19
CAS:CP19 blocks histamine receptors; inhibits EBOV and MARV with IC50s of 3.4 μM and 29.5 μM, respectively; antiviral [1].Formula:C26H30N2O5Color and Shape:SolidMolecular weight:450.53NAEPA
CAS:<p>NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor.</p>Formula:C20H40NO5PPurity:98%Color and Shape:SolidMolecular weight:405.51GTS-21
CAS:GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.Formula:C19H20N2O2Purity:98%Color and Shape:SolidMolecular weight:308.37EP2 receptor antagonist-1
CAS:EP2 receptor antagonist-1: reversible, potent, depends on agonist; anti-inflammatory.Formula:C24H22N4O5Color and Shape:SolidMolecular weight:446.46Zaltidine
CAS:Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.Formula:C8H10N6SPurity:98%Color and Shape:SolidMolecular weight:222.27Detomidine
CAS:Detomidine is a nonnarcotic, synthetic α2-adrenergic agonist. Detomidine produces dose-dependent sedative and analgesic effects.Formula:C12H14N2Purity:98%Color and Shape:White Crystalline PowderMolecular weight:186.25RG-12915
CAS:RG-12915 is a selective antagonist of 5-HT3(IC50 value of 0.16 nM).Formula:C20H25ClN2O2Purity:98%Color and Shape:SolidMolecular weight:360.88Indatraline hydrochloride
CAS:Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET)Formula:C16H16Cl3NPurity:98%Color and Shape:SolidMolecular weight:328.66Abanoquil
CAS:Abanoquil is an antagonist of alpha-1 adrenoceptor.Formula:C22H25N3O4Color and Shape:SolidMolecular weight:395.45PD-135666
CAS:PD-135666 is an antagonist of CCK receptor.Formula:C33H39N3O5Purity:98%Color and Shape:SolidMolecular weight:557.68Tiamenidine
CAS:Tiamenidine is an antagonist of centrally-acting alpha1 adrenergic receptor.Formula:C8H10ClN3SPurity:98%Color and Shape:SolidMolecular weight:215.7JMV3002
CAS:JMV3002, a ghrelin receptor foe, blocks hexarelin-induced eating in rats by up to 98% without affecting growth hormone release.Formula:C35H34N6O3Color and Shape:SolidMolecular weight:586.68LY320135
CAS:CB1 receptor antagonist/inverse agonistFormula:C24H17NO4Purity:98%Color and Shape:SolidMolecular weight:383.4CB2R agonist 1
CAS:CB2R agonist 1 selectively binds human CB2R, EC50 of 0.56 µM, modulates inflammatory cytokines.Formula:C22H32N2OColor and Shape:SolidMolecular weight:340.5BIIL 260
CAS:BIIL 260 is a leukotriene B4 (BLT1) receptor antagonist with anti-inflammatory activity.Formula:C30H30N2O3Color and Shape:SolidMolecular weight:466.57Ampreloxetine
CAS:Ampreloxetine (TD-9855) is a norepinephrine reuptake inhibitor used to study neurological diseases.Formula:C18H18F3NOPurity:98%Color and Shape:SolidMolecular weight:321.34RB-005
CAS:RB-005 is a potent SK1 inhibitor with IC(50) of 3.6 μM, potentially treating proliferative diseases like hypertension and degrades SK1 in human cells.Formula:C21H35NOColor and Shape:SolidMolecular weight:317.51SR 49059
CAS:vasopressin V1A receptor antagonistFormula:C28H27Cl2N3O7SPurity:98%Color and Shape:SolidMolecular weight:620.5IMTPPE
CAS:IMTPPE inhibits transcriptional activity and protein level of AR in C4-2 prostate cancer cells. It also inhibits AR-target gene expression.Formula:C20H27N3O2SColor and Shape:SolidMolecular weight:373.51SANT-2
CAS:SANT-2 is a potent inhibitor of Shh signaling pathway.Formula:C23H20ClN3O4Color and Shape:SolidMolecular weight:437.88Nivasorexant
CAS:Nivasorexant is a potent antagonist of the orexin receptor.Formula:C23H23N7O2Color and Shape:SolidMolecular weight:429.47ATL-801
CAS:ATL-801 is anselective antagonist of A2B receptor with herapeutic activity for colitis.Formula:C24H25N7O3Color and Shape:SolidMolecular weight:459.5Napamezole
CAS:Napamezole: α2 adrenergic receptor antagonist, blocks α1 in rat vas deferens (Kb 135 nM), reverses clonidine effects on twitch height.Formula:C14H16N2Purity:98%Color and Shape:SolidMolecular weight:212.29UCSF686
CAS:UCSF686, a UCSF678 analog, lacks 5-HT5A potency but keeps affinity for 5-HT1A, 5-HT2B, 5-HT7, and serves as a control.Formula:C14H19N3O2SColor and Shape:SolidMolecular weight:293.38CCK-B Receptor Antagonist 1
CAS:CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor agonist and has the potential of reducing the secretion of gastric acid.Formula:C28H30N6O3Purity:98%Color and Shape:SolidMolecular weight:498.58N,N-Dimethylsphingosine
CAS:<p>N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.</p>Formula:C20H41NO2Purity:98%Color and Shape:Clear Colorless To Faint Yellow Liquid/White To Off-White PowderMolecular weight:327.55DMP 696
CAS:DMP 696 is a selective antagonist of corticotropin-releasing hormone receptor 1. It is used for the treatment of anxiety and depression.Formula:C18H21Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:410.3Neladenoson dalanate HCl
CAS:Neladenoson dalanate HCl is a potent, selective, orally active partial agonist of adenosine A1 receptor (EC50: 0.1 nM).Formula:C35H35Cl2N7O4S2Purity:98%Color and Shape:SolidMolecular weight:752.73SSTR4 agonist 3
CAS:SSTR4 agonist 3 activates SSTR4 in the hippocampus and neocortex, aiding memory and learning, and shows potent pain relief in rodents.Formula:C18H24N4OSColor and Shape:SolidMolecular weight:344.47INCB38579
CAS:INCB38579: Oral, selective H4 antagonist; crosses brain barrier; IC50s - hH4R: 4.8 nM, mH4R: 42 nM, rH4R: 32 nM; anti-inflammatory and antipruritic.Formula:C25H34N6OColor and Shape:SolidMolecular weight:434.58Adenosine receptor inhibitor 2
CAS:Compound 14b is a potent AR inhibitor with dual affinity, stronger for A1 (Ki = 52.2 nM) than A2A (Ki = 167 nM) ARs.Formula:C17H20BrN5O2Color and Shape:SolidMolecular weight:406.28BAY-u 9773
CAS:BAY-u9773 is a non-selective CysLT receptor antagonist with similar IC50 for CysLT1 and CysLT2, inhibiting LT responses.Formula:C27H36O5SColor and Shape:White OilMolecular weight:472.64BMS-466442
CAS:BMS-466442 is the first selective amino acid transporter alanine serine cysteine transporter-1 inhibitor.Formula:C31H30N4O5Color and Shape:SolidMolecular weight:538.59CB1 inverse agonist 2
CAS:CB1 inverse agonist 2, an oral drug, counters CB1 effects, reducing CP55940-induced hypothermia and anorexia in mice.Formula:C24H20ClFN2OSColor and Shape:SolidMolecular weight:438.94Remogliflozin
CAS:Remogliflozin is an effective sodium-glucose transporter 2 inhibitor (Kis = 12.4 and 26 nM for human and rat SGLT2, respectively).Formula:C23H34N2O7Color and Shape:SolidMolecular weight:450.53Penbutolol
CAS:Penbutolol is a nonselective beta-blocker utilized as an antihypertensive and an antianginal.Formula:C18H29NO2Purity:98%Color and Shape:SolidMolecular weight:291.43SB269652
CAS:SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor.Formula:C27H30N4OPurity:98%Color and Shape:SolidMolecular weight:426.55Acreozast
CAS:Acreozast, a histamine release inhibitor, is used potentially for the treatment of asthma and atopic dermatitis.Formula:C15H14ClN3O6Color and Shape:SolidMolecular weight:367.74Phenindamine
CAS:Phenindamine (Nu 1504) is an H1-receptor antagonist which is antihistamine[1].Formula:C19H19NColor and Shape:SolidMolecular weight:261.36Bifeprunox Mesylate
CAS:Bifeprunox: partial dopamine/serotonin agonist for schizophrenia; suppresses VTA neurons via D2; affects rat nicotine-seeking.Formula:C25H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:481.56BI-L 239
CAS:BI-L 239 is an inhibition of 5-lipoxygenase products that cause bronchoconstriction.Formula:C16H15FOColor and Shape:SolidMolecular weight:242.29ATC0065 HCl
CAS:ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist.Formula:C25H31BrCl2F3N5OColor and Shape:SolidMolecular weight:625.35MAT2A-IN-3
CAS:MAT2A-IN-3: potent MAT2A inhibitor, hinders MTAP-deficient cancer cell growth, potential for cancer research.Formula:C24H16F5N5O3Color and Shape:SolidMolecular weight:517.415-HT2A receptor agonist-2
CAS:Potent 5-HT2A receptor agonist-2 targets 5-HT2A/B/C with EC50 1.7, 0.58, 0.50 nM.Formula:C20H21ClN2O3Color and Shape:SolidMolecular weight:372.85PD 119819
CAS:PD 119819 is a heterocyclic piperazine. PD 119819 is an extremely selective DA autoreceptor agonist.Formula:C21H25Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:438.35Antiplatelet agent 2
CAS:Antiplatelet agent 2 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies.Formula:C21H24F2N6O4SColor and Shape:SolidMolecular weight:494.51Edivoxetine
CAS:Edivoxetine (LY2216684) is a selective norepinephrine reuptake inhibitor for ADHD and depression.Formula:C18H26FNO4Color and Shape:SolidMolecular weight:339.4Nelonicline
CAS:Nelonicline is a selective agonist of neuronal nicotinic receptors.Formula:C17H19N3OSPurity:98%Color and Shape:SolidMolecular weight:313.42ChemR23-IN-1
CAS:ChemR23-IN-1 inhibits human and mouse ChemR23 (IC50: 38 nM, 100 nM) and stops CAL-1 chemotaxis induced by Chemerin in vitro.Formula:C28H29N7O2Color and Shape:SolidMolecular weight:495.58RWJ 52353
CAS:α2D adrenergic receptor agonistFormula:C11H10N2SPurity:98%Color and Shape:SolidMolecular weight:202.28ST-198
CAS:ST-198 is a dopamine D3 receptor antagonist.Formula:C22H26N2OPurity:98%Color and Shape:SolidMolecular weight:334.45Eplivanserin hemifumarate
CAS:Eplivanserin is an inverse agonist of 5-HT2A.Formula:C23H25FN2O6Color and Shape:SolidMolecular weight:444.45EMD 56551
CAS:<p>EMD 56551 is a selective small molecule 5-HT1A receptor agonist with anxiolytic activity for the study of anxiety disorders.</p>Formula:C24H31N3O2Purity:95.64% - 99.39%Color and Shape:SolidMolecular weight:393.522CL-184005
CAS:CL-184005 is a PAF inhibitor that blocks tumor necrosis factor synthesis and reduces spleen-associated TNF protein.Formula:C33H46NO7PSColor and Shape:SolidMolecular weight:631.76Guanoxabenz hydrochloride
CAS:<p>Guanoxabenz hydrochloride, α2 adrenergic receptor agonist; Ki: 4000 nM, α2A form Ki: 40 nM.</p>Formula:C8H9Cl3N4OColor and Shape:SolidMolecular weight:283.54Alprenolol tartrate, (S)-
CAS:Alprenolol tartrate, (S)- is an 5-HT1A antagonist.Formula:C19H29NO8Purity:98%Color and Shape:SolidMolecular weight:399.44Sultopride
CAS:Sultopride is a compound that an amino on the sulfamide group of sulpiride is replaced by an ethyl group.Formula:C17H26N2O4SColor and Shape:SolidMolecular weight:354.46Medroxalol
CAS:Medroxalol (RMI81968), an oral α- & β-adrenergic blocker, has antihypertensive and vasodilatory effects.Formula:C20H24N2O5Color and Shape:SolidMolecular weight:372.42(R)-Mequitazine
CAS:<p>(R)-Mequitazine, a muscarinic acetylcholine receptor (M-AChRs) antagonist, is used potentially for the treatment of asthma.</p>Formula:C20H22N2SColor and Shape:SolidMolecular weight:322.47(Rac)-WAY-161503
CAS:(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.Formula:C11H11Cl2N3OPurity:99.51%Color and Shape:SolidMolecular weight:272.13SLV-310
CAS:SLV-310 is a D2 receptor antagonist and 5-HT reuptake receptor inhibitor for the study of neurological disorders such as bipolar disorder and schizophrenia.Formula:C25H24FN3O2Purity:99.39%Color and Shape:SolidMolecular weight:417.48Bufetolol
CAS:Bufetolol is an antagonist of beta-adrenoceptor.Formula:C18H29NO4Purity:98%Color and Shape:SolidMolecular weight:323.43GPR183-IN-2
CAS:<p>GPR183-IN-2 (compound 23) is an effective, orally active inhibitor of GPR183, displaying an IC50 value of 39.45 nM in Ca2+ mobilization assays. This compound has potential applications in research related to cancer, autoimmune diseases, pain, and osteoporosis.</p>Formula:C19H23BrN2O3Color and Shape:SolidMolecular weight:407.3Kadsurenone
CAS:Kadsurenone, from haifenteng, blocks PAF/PTAFR pathway, promising for breast cancer bone metastases treatment.Formula:C21H24O5Color and Shape:SolidMolecular weight:356.41Mosapramine
CAS:Mosapramine is a dopamine D2-receptor antagonist.Formula:C28H35ClN4OPurity:98%Color and Shape:SolidMolecular weight:479.06SNT-207858 free base
CAS:SNT-207858: selective MC-4 receptor antagonist, passes blood-brain barrier, orally active, IC50: 22 nM (binding), 11 nM (function).Formula:C32H43Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:616.62Apadenoson
CAS:<p>Apadenoson: potent A2 agonist, A3 inhibitor (IC 45 nM), anti-inflammatory, for neurological research.</p>Formula:C23H30N6O6Purity:98%Color and Shape:SolidMolecular weight:486.52Zolantidine dimaleate
CAS:H2 receptor antagonistFormula:C26H31N3O5SPurity:98%Color and Shape:SolidMolecular weight:497.61BMS-665053
CAS:BMS-665053: CRF1 receptor antagonist, IC50 = 1.0 nM; inhibits cAMP in Y-79 cells, IC50 = 4.9 nM; anti-anxiety in rats, Cl = 17 mL/min/kg, t½ = 7.8 h.Formula:C16H14Cl3F2N3O2Purity:98%Color and Shape:SolidMolecular weight:424.66VUF 8430 dihydrobromide
CAS:histamine H4 receptor full agonistFormula:C4H12BrN5SPurity:98%Color and Shape:SolidMolecular weight:242.14Undecylenoyl phenylalanine
CAS:<p>Undecylenoyl phenylalanine (Sepiwhite msh QD) is a novel depigmenting agent, which possibly acts as an alpha-melanocyte-stimulating hormone antagonist, thus</p>Formula:C20H29NO3Purity:≥98%Color and Shape:White To Pinkish Solid PowderMolecular weight:331.45Levobunolol
CAS:Levobunolol is a nonselective beta-blocker. It is used topically to treat glaucoma.Formula:C17H25NO3Color and Shape:White To Pink PowderMolecular weight:291.39AF40431
CAS:AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 μM; Kd: 0.7 μM). AF40431 is bound in the neurotensin-binding site of sortilin.Formula:C17H21NO5Color and Shape:SolidMolecular weight:319.35B-HT 933 dihydrochloride
CAS:<p>Azepexole (B-HT 933) dihydrochloride is an α2-adrenoceptor agonist, pKi: 8.3/α2A, 7.6/α2B, 7.5/α2C; IC50: 78.72 nM for peristalsis inhibition.</p>Formula:C9H17Cl2N3OColor and Shape:SolidMolecular weight:254.16WAY 629 hydrochloride
CAS:5-HT2C agonistFormula:C15H19ClN2Purity:98%Color and Shape:SolidMolecular weight:262.78CB1-IN-2
CAS:CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.Formula:C17H19Cl2N5OColor and Shape:SolidMolecular weight:380.27Broxaterol
CAS:Broxaterol is a β2 adrenoreceptor agonist. It is part of a class of drugs that affect the smooth muscle receptors in the body.Formula:C9H15BrN2O2Purity:98%Color and Shape:SolidMolecular weight:263.13JHW 007 hydrochloride
CAS:JHW 007 hydrochloride is a Dopamine uptake inhibitor.Formula:C24H30ClF2NOPurity:98%Color and Shape:SolidMolecular weight:421.95CFM 1571 hydrochloride
CAS:CFM 1571 hydrochloride stimulates sGC with EC50 of 5.49 μM; potential for cardiovascular research.Formula:C23H29ClN4O3Color and Shape:SolidMolecular weight:444.96KUL-7211 racemate
CAS:KUL 7211, a selective β-adrenoceptor agonist, exists as a racemate, referred to as KUL 7211 racemate, which is the mixture of its enantiomers.Formula:C19H23NO5Purity:98%Color and Shape:SolidMolecular weight:345.39SGS518 oxalate
CAS:SGS518 oxalate is a 5-HT6 antagonist.Formula:C23H24F2N2O7SPurity:98%Color and Shape:SolidMolecular weight:510.51JNJ 10181457 dihydrochloride
CAS:<p>JNJ 10181457 dihydrochloride is a Histamine H3 receptor antagonist.</p>Formula:C20H28N2OPurity:98%Color and Shape:SolidMolecular weight:312.45Substance P Receptor Antagonist 1
CAS:<p>Substance P Receptor Antagonist 1 may aid in treating GI, inflammatory, respiratory, and CNS disorders.</p>Formula:C24H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:434.49
