GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,024 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,029 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(159 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(443 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(196 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(326 products)
- PAFR(14 products)
- PKA(53 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5980 products of "GPCR/G-Protein"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
K-(D-1-Nal)-FwLL-NH2
CAS:Potent ghrelin receptor inverse agonist with Ki of 4.9/31 nM in COS7/HEK293T; blocks Gq/G13 signaling.Formula:C51H67N9O6Purity:98%Color and Shape:SolidMolecular weight:902.13Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA
Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 receptor (MC2) agonist.Formula:C212H316F3N57O59SPurity:98%Color and Shape:SolidMolecular weight:4696.18P2Y6R antagonist 1
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active antagonist of P2Y6R, featuring an IC50 value of 19.6 nM. This compound also exhibits anti-inflammatory properties.Color and Shape:Odour Solid1-39-Corticotropin (human)(TFA)
ACTH (1-39) human (TFA) is a melanocortin agonist that boosts adrenal CS production and affects the CNS and immune system.Formula:C207H308N56O58S·C2HF3O2Purity:98%Color and Shape:SolidMolecular weight:4655.16Dulaglutide
CAS:Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).Color and Shape:SolidCAY10580
CAS:CAY10580 is a potent and selective prostaglandin EP 4 receptor agonist ( K i =35 nM).Formula:C19H35NO4Color and Shape:SolidMolecular weight:341.49Isobutyryl-L-carnitine
CAS:Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formula:C11H21NO4Purity:98%Color and Shape:SolidMolecular weight:231.29Protease-Activated Receptor-1 antagonist 2
CAS:Orally active PAR-1 antagonist with 7 nM IC50; potential for CVD research.Formula:C24H23F2N3O2Color and Shape:SolidMolecular weight:423.46Mabuterol free base
CAS:Mabuterol: selective β2 agonist, inhibits isoprenaline, affects rat uterus and rabbit jejunum, alters intestinal propulsion.Formula:C13H18ClF3N2OPurity:98%Color and Shape:SolidMolecular weight:310.74GLP-1 (9-36) amide
CAS:GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor.Formula:C140H214N36O43Purity:97%Color and Shape:SolidMolecular weight:3089.41(3R,5R,6S)-Atogepant
(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.Formula:C29H23F6N5O3Color and Shape:SolidMolecular weight:603.52TGR5 agonist 4
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].Formula:C24H38F2O5Color and Shape:SolidMolecular weight:444.55RF9 acetate
RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.Formula:C28H42N6O5Purity:99.77%Color and Shape:SolidMolecular weight:542.67Ref: TM-T16738L
1mg65.00€5mg125.00€10mg182.00€25mg325.00€50mg467.00€100mg645.00€200mg868.00€1mL*10mM (DMSO)167.00€Maceneolignan H
CAS:Maceneolignan H, a neolignane from Myristica fragrans, selectively blocks CCR3 (EC50=1.4μM) with allergy research potential.Formula:C24H30O7Color and Shape:SolidMolecular weight:430.49CYN 154806
CAS:CYN 154806: potent sst2 antagonist; pIC50: 8.58 (sst2), 5.41 (sst1), 6.07 (sst3), 5.76 (sst4), 6.48 (sst5).Formula:C56H68N12O14S2Purity:98%Color and Shape:SolidMolecular weight:1197.34MK-7246 S enantiomer
MK-7246 S enantiomer is a potent and selective CRTH2 antagonist.Formula:C21H21FN2O4SPurity:98%Color and Shape:SolidMolecular weight:416.47tetranor-PGJM
CAS:<p>Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.</p>Formula:C16H22O6Color and Shape:SolidMolecular weight:310.346CB2R probe 1
CAS:<p>CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of</p>Formula:C36H42N4O4Color and Shape:SolidMolecular weight:594.74Secretin, porcine
CAS:Porcine secretin: 27-amino acid peptide for diagnosing pancreatic dysfunction and gastrinoma, stimulates bicarbonate fluid.Formula:C130H220N44O41·xC2H4O2Purity:98%Color and Shape:SolidMolecular weight:N/APSB 0777 ammonium salt
CAS:adenosine A2A receptor full agonistFormula:C18H24N6O7S2Purity:98%Color and Shape:SolidMolecular weight:500.55Tafluprost acid
CAS:Tafluprost acid is a selective agonist at the prostaglandin F receptor.Formula:C22H28F2O5Color and Shape:SolidMolecular weight:410.46Zicronapine fumarate
CAS:Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.Formula:C26H31ClN2O4Color and Shape:SolidMolecular weight:470.99Anthramycin
CAS:Anthramycin: a PBD family antibiotic with antitumor effects and CNS cholecystokinin antagonist properties in mice.Formula:C16H17N3O4Color and Shape:SolidMolecular weight:315.32L-threo Lysosphingomyelin (d18:1)
CAS:L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).Formula:C23H49N2O5PColor and Shape:SolidMolecular weight:464.62Ontazolast
CAS:Ontazolast: a small-molecule LTB4R antagonist targeting asthma and immune disorders.Formula:C21H25N3OPurity:99.94%Color and Shape:SoildMolecular weight:335.44Heterobivalent ligand-1
Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.Formula:C86H115FN16O21Color and Shape:SolidMolecular weight:1727.93NESS 0327
CAS:NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.Formula:C24H23Cl3N4OPurity:99.78%Color and Shape:SolidMolecular weight:489.82[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS:Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.Formula:C50H75N15O10Purity:98%Color and Shape:SolidMolecular weight:1046.23Thromboxane B1
CAS:Thromboxane B1 (TXB1) is a lipid eicosanoid, part of the TXB family, involved in blood clotting.Formula:C20H36O6Color and Shape:SolidMolecular weight:372.5Corynanthine
CAS:Corynanthe is a plant alkaloid. Corynanthe also has an alpha-2-adrenergic blocking activity.Formula:C21H26N2O3Purity:98%Color and Shape:SolidMolecular weight:354.44Fluphenazine free base
CAS:Flufenazine: antipsychotic for schizophrenia, blocks dopamine D2 receptors, reduces hallucinations and delusions.Formula:C22H26F3N3OSColor and Shape:SolidMolecular weight:437.52PD 142893
CAS:PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.Formula:C50H65N7O10Purity:98%Color and Shape:SolidMolecular weight:924.09Pancreatic polypeptide TFA
Pancreatic polypeptide TFA acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.Color and Shape:Odour SolidSarafotoxin S6b
CAS:non-selective endothelin receptor agonistFormula:C110H163N27O34S5Purity:98%Color and Shape:SolidMolecular weight:2567.96Guanylin TFA (mouse,rat)
Guanylin (mouse, rat) TFA is a peptide composed of 15 amino acids and acts as an activator of intestinal guanylate cyclase. This compound is utilized in research related to diarrhea.Formula:C60H90N16O22S4·xC2HF3O2Color and Shape:SolidMolecular weight:1515.71 (free base)15-keto-17-phenyl trinor Prostaglandin F2α
CAS:Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.Formula:C23H30O5Color and Shape:SolidMolecular weight:386.488(+)-Cloprostenol
CAS:(+)-Cloprostenol is a analogue of prostaglandin F2α (PGF2α), and is selective prostaglandin receptor agonistic.Formula:C22H29ClO6Purity:98%Color and Shape:SolidMolecular weight:424.92Fasitibant chloride
CAS:<p>Fasitibant chloride, a potent B2R blocker, alleviates pain and swelling in arthritis.</p>Formula:C36H49Cl3N6O6SColor and Shape:SolidMolecular weight:800.23Amitraz
CAS:Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.Formula:C19H23N3Purity:99.88%Color and Shape:White/Pale Yellow Crystalline SolidMolecular weight:293.41Cetirizine Impurity D
CAS:Cetirizine Impurity D, an antihistamine derivative, acts as a long-lasting H1-receptor antagonist with antiallergic effects.Formula:C30H28Cl2N2Color and Shape:SolidMolecular weight:487.46PHM-27 (human)
CAS:<p>Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.</p>Formula:C135H214N34O40SPurity:98%Color and Shape:SolidMolecular weight:2985.44AdTx1
Selective non-competitive α1A adrenoceptor antagonist with Ki of 0.35 nM; inactive on other GPCRs; affects phenylephrine actions.Formula:C310H481N87O100S8Purity:98%Color and Shape:SolidMolecular weight:7283.22Taspoglutide
CAS:Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetesFormula:C152H232N40O45Purity:98%Color and Shape:SolidMolecular weight:3339.763KwFwLL-NH2
CAS:KwFwLL-NH2 is a hexapeptide that serves as a ligand for the ghrelin receptor (ghrelin receptor). This compound acts as a specific inverse agonist for the ghrelin receptor, exhibiting moderate potency (EC50=45.6 nM).Formula:C49H66N10O6Color and Shape:SolidMolecular weight:891.11Spns2-IN-2
Spns2-IN-2 (compound 3a) is an inhibitor of SPNS2.Formula:C22H30ClN3O2Color and Shape:SolidMolecular weight:403.95Sauvagine
CAS:CRF receptor agonist; Ki: 9.4 nM (hCRF-R1), 9.9 nM (rCRF-R2a), 3.8 nM (mCRF-R2b) for 125I-[D-Tyr1]astressin binding inhibition.Formula:C202H346N56O63SPurity:98%Color and Shape:SolidMolecular weight:4599.35β-CGRP (mouse)
β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.Formula:C165H265N49O55S2Color and Shape:SolidMolecular weight:3879.29Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formula:C27H35ClFN3O11Purity:98%Color and Shape:SolidMolecular weight:632.04Pasireotide pamoate
CAS:Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.Formula:C81H82N10O15Purity:98%Color and Shape:SolidMolecular weight:1435.58HAEGTFTSD
CAS:HAEGTFTSD is GLP-1's initial segment; GLP-1 (7-36) amide, tied to food intake, stems from preproglucagon in L-cells.Formula:C40H57N11O17Purity:98%Color and Shape:SolidMolecular weight:963.94
![[Phe8Ψ(CH-NH)-Arg9]-Bradykinin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP2076.webp&w=3840&q=75)
