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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5745 products of "GPCR/G-Protein"

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  • NF 340
    Targetmol
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    NF 340

    CAS:
    P2Y11 antagonist
    Formula:C37H30N4Na4O15S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:990.87

    Ref: TM-T23064

  • Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
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    Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2

    CAS:
    <p>Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype</p>
    Formula:C42H63FN12O8
    Color and Shape:Solid
    Molecular weight:883.02

    Ref: TM-T80240

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    U-46619 serinol amide

    U-46619 serinol amide is a derivative of U-46619, acting as a stable analog of Thromboxane A2 (TXA2). It effectively functions as a TXA2 agonist, capable of inducing platelet shape change and aggregation.
    Formula:C24H41NO5
    Color and Shape:Solid
    Molecular weight:423.29847

    Ref: TM-T207554

  • Triazolomethylindole-3-acetic acid
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    Triazolomethylindole-3-acetic acid

    CAS:
    <p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>
    Formula:C13H12N4O2
    Color and Shape:Solid
    Molecular weight:256.26

    Ref: TM-T203624

  • [Phe8Ψ(CH-NH)-Arg9]-Bradykinin
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    [Phe8Ψ(CH-NH)-Arg9]-Bradykinin

    CAS:
    Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.
    Formula:C50H75N15O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1046.23

    Ref: TM-TP2076

  • Osanetant
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    Osanetant

    CAS:
    Osanetant produces anxiolytic- and antidepressant-like effects. Osanetant is a selective NK3 receptor antagonist. It is researched for schizophrenia.
    Formula:C35H41Cl2N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:606.62

    Ref: TM-T16408

  • B-Raf IN 14
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    B-Raf IN 14

    CAS:
    B-Raf IN 14 is a BRAF inhibitor.
    Formula:C15H14BrN5O3S
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:424.27

    Ref: TM-T72070

  • Xanthine amine congener dihydrochloride
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    Xanthine amine congener dihydrochloride

    CAS:
    <p>XAC dihydrochloride is an Adenosine A1 and A2 receptor antagonist with IC50s of 1.8 nM and 114 nM, also a mouse convulsant.</p>
    Formula:C21H30Cl2N6O4
    Color and Shape:Solid
    Molecular weight:501.41

    Ref: TM-T39387

  • Succinate/succinate receptor antagonist 1
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    Succinate/succinate receptor antagonist 1

    CAS:
    <p>Potent succinate receptor antagonist with IC50 of 20 μM; blocks gingival succinate signaling, may treat periodontal disease.</p>
    Formula:C17H15N3O
    Purity:99.53%
    Color and Shape:Soild
    Molecular weight:277.32

    Ref: TM-T67915

  • sGnRH-A
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    sGnRH-A

    CAS:
    <p>sGnRH-A, a salmon GnRH analog, boosts growth hormone and induces ovulation for artificial insemination.</p>
    Formula:C64H83N17O12
    Color and Shape:Solid
    Molecular weight:1282.45

    Ref: TM-T76312

  • Naratriptan D3 Hydrochloride
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    Naratriptan D3 Hydrochloride

    CAS:
    Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.
    Formula:C17H26ClN3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:374.94

    Ref: TM-T12176

  • (+)-Cloprostenol
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    (+)-Cloprostenol

    CAS:
    <p>(+)-Cloprostenol is a analogue of prostaglandin F2α (PGF2α), and is selective prostaglandin receptor agonistic.</p>
    Formula:C22H29ClO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:424.92

    Ref: TM-T13461

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    Pancreatic polypeptide TFA

    <p>Pancreatic polypeptide TFA acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP2887

  • MK-7246 S enantiomer
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    MK-7246 S enantiomer

    MK-7246 S enantiomer is a potent and selective CRTH2 antagonist.
    Formula:C21H21FN2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:416.47

    Ref: TM-T12067

  • MM 54
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    MM 54

    CAS:
    Potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM), counters [Pyr1]-Apelin-13, inhibits glioblastoma growth in mice.
    Formula:C70H121N29O15S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1737.15

    Ref: TM-TP2001

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    Dulaglutide

    CAS:
    <p>Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).</p>
    Color and Shape:Solid

    Ref: TM-T75718

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    P2Y6R antagonist 1

    P2Y6R antagonist 1 (compound 5ab) is a selective, orally active antagonist of P2Y6R, featuring an IC50 value of 19.6 nM. This compound also exhibits anti-inflammatory properties.
    Color and Shape:Odour Solid

    Ref: TM-T200515

  • (p-Iodo-Phe7)-ACTH (4-10)
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    (p-Iodo-Phe7)-ACTH (4-10)

    CAS:
    <p>(p-Iodo-Phe7)-ACTH (4-10), an ACTH derivative and MC receptor antagonist, inhibits α-MSH-induced grooming in rats.</p>
    Formula:C44H58IN13O10S
    Color and Shape:Solid
    Molecular weight:1087.98

    Ref: TM-T76303

  • CB2R probe 1
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    CB2R probe 1

    CAS:
    <p>CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of</p>
    Formula:C36H42N4O4
    Color and Shape:Solid
    Molecular weight:594.74

    Ref: TM-T74604

  • 4-fluoro MBZP
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    4-fluoro MBZP

    CAS:
    <p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>
    Formula:C12H17FN2
    Color and Shape:Solid
    Molecular weight:208.28

    Ref: TM-T203276

  • Adrenocorticotropic Hormone (ACTH) (1-39), rat
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    Adrenocorticotropic Hormone (ACTH) (1-39), rat

    CAS:
    ACTH (1-39), rat: potent MC2 agonist, forms fragments in vitro, isolated by HPLC, characterized by amino acids and NH2-terminus.
    Formula:C210H315N57O57S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4582.23

    Ref: TM-TP1249

  • Cinnamtannin A2
    Targetmol
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    Cinnamtannin A2

    CAS:
    <p>Cinnamtannin A2, a tetrameric procyanidin, boosts GLP-1, insulin, CRH expression, and has antioxidant, anti-diabetic, nephroprotective properties.</p>
    Formula:C60H50O24
    Color and Shape:Solid
    Molecular weight:1155.02

    Ref: TM-T40977

  • α-MSH TFA
    Targetmol
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    α-MSH TFA

    CAS:
    <p>α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the</p>
    Formula:C79H110F3N21O21S
    Color and Shape:Solid
    Molecular weight:1778.93

    Ref: TM-T35406

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    JKC363 TFA

    JKC363 TFA is an MC4 receptor antagonist with 90x more affinity than MC3 (IC50: 0.5 nM vs 44.9 nM), blocks α-MSH's effect on TRH, and is anti-hyperalgesic.
    Formula:C71H93F3N19O18S2
    Color and Shape:Solid
    Molecular weight:1620.73

    Ref: TM-T75850

  • Cortistatin 14, human, rat acetate
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    Cortistatin 14, human, rat acetate

    Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and
    Formula:C80H112N18O19S2
    Purity:97.86%
    Color and Shape:Solid
    Molecular weight:1693.98

    Ref: TM-TP1188L

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    ELA-11(human) TFA

    <p>ELA-11(human) TFA: apelin receptor agonist, K i =14 nM, inhibits cAMP, stimulates β-arrestin, from ELA-32 fragment.</p>
    Formula:C60H91F3N16O15S2
    Color and Shape:Solid
    Molecular weight:1397.58

    Ref: TM-T76053

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    Cagrilintide

    CAS:
    <p>Cagrilintide: a long-acting amylin analogue, potential obesity treatment, reduces appetite and weight.</p>
    Formula:C194H312N54O59S2
    Color and Shape:Solid
    Molecular weight:4409.01

    Ref: TM-T76262

  • PAR-4 Agonist Peptide, amide acetate
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    PAR-4 Agonist Peptide, amide acetate

    PAR-4 Agonist Peptide, amide acetate is an agonist of proteinase-activated receptor-4 (PAR-4).
    Formula:C36H52N8O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:740.86

    Ref: TM-T7623L

  • 5-Bromoimidazo[1,2-A]Pyrazine
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    5-Bromoimidazo[1,2-A]Pyrazine

    CAS:
    5-Bromoimidazo[1,2-a]pyrazine inhibits phosphodiesterase and beta-adrenergic receptors.5-Bromoimidazo[1,2-a]pyrazine shows antibronchospastic activity in vitro.
    Formula:C6H4BrN3
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:198.02

    Ref: TM-T77641

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    BA 1 TFA

    <p>BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.</p>
    Formula:C59H77F3N14O13
    Color and Shape:Solid
    Molecular weight:1247.32

    Ref: TM-T75945

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    Exendin-4 (3-39)

    CAS:
    <p>Exendin-4 (3-39) is a truncated peptide missing first 2 amino acids of Exendin-4, a potent GLP-1r agonist used in diabetes and HPA axis research.</p>
    Formula:C176H272N46O58S
    Color and Shape:Solid
    Molecular weight:3992.44

    Ref: TM-T76290

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    20-SOLA

    <p>20-SOLA is the first water-soluble 20-HETE antagonist with oral bioavailability. It significantly improves blood pressure changes and kidney damage associated with the streptozotocin (STZ) diabetic mouse model. Additionally, 20-SOLA acts as a GPR75 receptor blocker. This compound is useful in research related to cardiovascular pathology.</p>
    Formula:C33H62O9
    Molecular weight:602.43938

    Ref: TM-T208783

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    GRL018-21

    GRL018-21 is a potent, highly selective inhibitor of G protein-coupled receptor kinase 5 (GRK5), exhibiting an IC50 of 10 nM [1].
    Color and Shape:Odour Solid

    Ref: TM-T82258

  • Dapiglutide
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    Dapiglutide

    CAS:
    <p>Dapiglutide (ZP7570) is a long-acting GLP-1R &amp; GLP-2R dual agonist for SBS research.</p>
    Color and Shape:Solid

    Ref: TM-T39820

  • INCB 3284 dimesylate
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    INCB 3284 dimesylate

    CAS:
    INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.
    Formula:C28H39F3N4O10S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:712.76

    Ref: TM-T11647

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    Imelciment

    CAS:
    <p>Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.</p>
    Purity:95%
    Color and Shape:Soild

    Ref: TM-T9901A-366

  • BAM(8-22)
    Targetmol
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    BAM(8-22)

    CAS:
    <p>Potent MRGPRX1 agonist peptide; first found in bovine adrenal glands. Non-opioid, lacking met-enkephalin motif. EC50: 8-150 nM.</p>
    Formula:C91H127N25O23S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1971.22

    Ref: TM-TP1914

  • Bombinakinin M acetate
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    Bombinakinin M acetate

    <p>Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is</p>
    Formula:C102H163N31O26
    Purity:99.80%
    Color and Shape:Solid
    Molecular weight:2239.58

    Ref: TM-TP2075L

  • Dipentylone hydrochloride
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    Dipentylone hydrochloride

    CAS:
    Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.
    Formula:C14H20ClNO3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:285.77

    Ref: TM-T205977

  • 12(S)-HpEPE
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    12(S)-HpEPE

    CAS:
    <p>12(S)-HpEPE, a fatty acid created by 12-lipoxygenase on EPA, has unclear biological activities but may resemble 12(S)-HpETE.</p>
    Formula:C20H30O4
    Color and Shape:Solid
    Molecular weight:334.456

    Ref: TM-T37968

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    Poly-D-lysine hydrobromide (MW 1000-5000)

    <p>Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.</p>
    Color and Shape:Odour Solid

    Ref: TM-TCL-01108

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    CKLF1-C27 TFA

    <p>CKLF1-C27 peptide activates ERK1/2 via CCR4, competes with CKLF1, promotes HUVEC growth, and has psoriasis research potential.</p>
    Formula:C153H244F3N39O39
    Color and Shape:Solid
    Molecular weight:3310.8

    Ref: TM-T76245L

  • 4-Chloromethamphetamine hydrochloride
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    4-Chloromethamphetamine hydrochloride

    CAS:
    <p>4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.</p>
    Formula:C10H15Cl2N
    Color and Shape:Solid
    Molecular weight:220.14

    Ref: TM-T203542

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    Efranarelaxin alfa

    CAS:
    <p>Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.</p>
    Color and Shape:Liquid

    Ref: TM-T9901A-865

  • Antisauvagine-30
    Targetmol
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    Antisauvagine-30

    CAS:
    <p>CRF2 receptor antagonist; Kd 1.4 nM (mCRF2β), 153.6 nM (rCRF1). Blocks sauvagine-induced cAMP in cells &amp; stress-related responses in mice.</p>
    Formula:C161H274N48O46S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3650.29

    Ref: TM-TP2091

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    Poly-D-lysine hydrobromide (MW 150000-300000)

    Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.
    Color and Shape:Odour Solid

    Ref: TM-TCL-01090

  • FR 113680
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    FR 113680

    CAS:
    FR 113680 is a tripeptide substance P antagonist with NK1 receptor selectivity.
    Formula:C35H39N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:625.726

    Ref: TM-T27360

  • 17-phenyl trinor Prostaglandin E2 ethyl amide
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    17-phenyl trinor Prostaglandin E2 ethyl amide

    CAS:
    17-phenyl trinor PGE2 ethyl amide, an EP1/EP3 agonist (Ki: 14-54 nM), enhances lipid solubility and tissue uptake, is a potent antifertility agent.
    Formula:C25H35NO4
    Color and Shape:Solid
    Molecular weight:413.55

    Ref: TM-T37996

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    Myristoylated ARF6 (2-13)

    Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.
    Formula:C74H128N16O18
    Molecular weight:1528.95925

    Ref: TM-TP3490

  • [Ala17]-MCH acetate
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    [Ala17]-MCH acetate

    <p>[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled).</p>
    Formula:C99H159N29O28S4
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:2331.76

    Ref: TM-TP1997L