GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(3,003 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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RC-3095 TFA
CAS:RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.Formula:C58H80F3N15O11Purity:98%Color and Shape:SolidMolecular weight:1220.34(Rac)-FK 480
CAS:(Rac)-FK 480 may be used to study epilepsy or anxiety disorders.Formula:C26H19FN4O2Purity:97.43%Color and Shape:SolidMolecular weight:438.45HAEGTFTSD acetate(926018-45-3 free base)
HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted fromFormula:C42H61N11O19Purity:98%Color and Shape:SolidMolecular weight:1024.01Sphingosine-1-phosphate (d16:1)
CAS:C16 S1P binds S1P1/EDG-1 (115%), S1P3/EDG-3 (83%), S1P2/EDG-5 (103%) receptors; elevated in glaucoma.
Formula:C16H34NO5PColor and Shape:SolidMolecular weight:351.424Parstatin(human)
CAS:Cell-permeable PAR1-derived peptide; inhibits endothelial migration, proliferation (IC50 ~3μM), induces apoptosis, and has cardioprotective effects.Formula:C191H330N64O53S3Purity:98%Color and Shape:SolidMolecular weight:4467.29HHS-0701
CAS:HHS-0701: SuTEx ligand, strong PTGR2 inhibitor, blocks 15-Keto-PGE2 metabolism.Formula:C20H20N4O3SPurity:97.24%Color and Shape:SoildMolecular weight:396.46K41498
CAS:Potent CRF2α/β antagonist; Ki: 0.66/0.62 nM, weak for CRF1 (425 nM). Blocks sauvagine in hCRF2 cells and urocortin hypotension in rats.Formula:C162H276N48O46Purity:98%Color and Shape:SolidMolecular weight:3632.26HCGRP-(8-37)
CAS:Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFormula:C139H230N44O38Purity:98%Color and Shape:SolidMolecular weight:3125.59Dexbrompheniramine maleate
CAS:Dexbrompheniramine is an antihistamine used for hay fever and urticaria, blocking H1 receptors in the body.Formula:C20H23BrN2O4Color and Shape:SolidMolecular weight:435.318Neuropeptide S(Rat)
CAS:Potent endogenous neuropeptide S receptor (NSPR) agonist (EC50 = 3.2 nM).Formula:C95H160N34O27Purity:98%Color and Shape:SolidMolecular weight:2210.52CB2R/FAAH modulator-2
CAS:CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.Formula:C24H33NO2Purity:99.15%Color and Shape:SoildMolecular weight:367.52GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Color and Shape:SolidMolecular weight:504.59CYM5442 hydrochloride
CAS:CYM 5442 HCl: potent, selective S1P1 agonist (EC50 = 1.35 nM), induces MAPK activation & lymphopenia, brain-penetrant.Formula:C23H28ClN3O4Color and Shape:SolidMolecular weight:445.94Sibenadet hydrochloride
CAS:Sibenadet, a D2/beta2-agonist, is potential useful for the treatment of symptoms of chronic obstructive pulmonary disease.Formula:C22H29ClN2O5S2Color and Shape:SolidMolecular weight:501.06ELA-11(human)
CAS:Apelin receptor agonist with high affinity (Ki = 14 nM). Blocks cAMP production and promotes β-arrestin activation; derived from ELA-32.Formula:C58H90N16O13S2Purity:98%Color and Shape:SolidMolecular weight:1283.57GLP-1R agonist 14
CAS:GLP-1R agonist 14, also known as Compound 14, is a potent agonist of the GLP-1 receptor, demonstrating an EC50 range of 0-20 nM against human GLP-1 [1].Formula:C45H42F2N10O5Color and Shape:SolidMolecular weight:840.88APJ receptor agonist 1
CAS:Potent APJ-R agonist 1, biphenyl acid, EC50: 0.093 nM (human), 0.12 nM (rat), targets apelin-13, promising for heart failure study.Formula:C31H26ClN3O3Color and Shape:SolidMolecular weight:524.02Detomidine carboxylic acid
CAS:Detomidine carboxylic acid, a urine metabolite of detomidine, is a synthetic α2-agonist, animal analgesic, with cardiac, respiratory, and diuretic effects.Formula:C12H12N2O2Purity:98%Color and Shape:SolidMolecular weight:216.24SRA880 malonate
CAS:SRA880: non-peptide sst(1) antagonist, low affinity for other sst receptors, binds dopamine D4, boosts SRIF, antidepressant-like effects.Formula:C29H36N4O8Purity:98%Color and Shape:SolidMolecular weight:568.62Prolactin Releasing Peptide (1-31), human
CAS:Human Prolactin Releasing Peptide (1-31) is a potent GPR10 agonist; Ki values are 1.03 nM (human) and 0.33 nM (rat).Formula:C160H252N56O42SPurity:98%Color and Shape:SolidMolecular weight:3664.15SR-140603
CAS:SR-140603, the less potent enantiomer of SR 140333, is used as the negative control.Formula:C37H45Cl3N2O2Purity:98%Color and Shape:SolidMolecular weight:656.12Des His1, Glu8 Exendin-4
Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.Formula:C179H277N47O59SPurity:99.92%Color and Shape:SolidMolecular weight:4063.46TAK-448 acetate
CAS:TAK-448 acetate (MVT-602 acetate) is a KISS1R agonist, a synthetic peptide similar to kisspeptin.Formula:C60H84N16O16Purity:99.88%Color and Shape:SolidMolecular weight:1285.41LY 293284
CAS:LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42(R,R)-Palonosetron Hydrochloride
CAS:(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFormula:C19H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:332.87PACAP (6-38), human, ovine, rat acetate
PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptorFormula:C184H303N55O48SPurity:99.84%Color and Shape:SoildMolecular weight:4085.84Pasireotide L-aspartate salt
CAS:Pasireotide L-aspartate, a stable cyclohexapeptide, mimics somatostatin with high affinity for sst1/2/3/4/5 receptors (pKi=8.2/9.0/9.1/<7.0/9.9).Formula:C62H73N11O13Purity:98%Color and Shape:SolidMolecular weight:1180.33PA-8
CAS:PA-8: Selective PAC1 antagonist, orally active, blocks CREB phosphorylation & cAMP increase (IC50=2nM), reduces pain & aversive response in vivo.Formula:C17H18N4O4Purity:97.54%Color and Shape:SolidMolecular weight:342.35CGRP 8-37 (rat)
CAS:CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.Formula:C138H224N42O41Purity:99.28%Color and Shape:SolidMolecular weight:3127.51Cetirizine methyl ester
CAS:Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.Formula:C22H27ClN2O3Color and Shape:SolidMolecular weight:402.91[D-Trp34]-Neuropeptide Y Acetate
[D-Trp34]-Neuropeptide Y Acetate is a potent Y5 receptor agonist that increases rat food intake; less potent at Y1, Y2, Y4, Y6.Formula:C198H293N55O58Purity:99.73%Color and Shape:SoildMolecular weight:4371.78CB2 receptor agonist 2
CAS:CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.
Formula:C30H36N2O4Purity:99.75%Color and Shape:SolidMolecular weight:488.62Pancreatic Polypeptide, rat
CAS:Rat Pancreatic Polypeptide: 36-amino acid peptide, NPYR4 agonist, secreted by islet PP cells.Formula:C195H298N58O57SPurity:98%Color and Shape:SolidMolecular weight:4398.87Bremelanotide
CAS:Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.Formula:C50H68N14O10Purity:98%Color and Shape:White PowderMolecular weight:1025.16Lys-[Des-Arg9]Bradykinin
CAS:Selective bradykinin B1 agonist with Ki 0.12 nM; inactive at B2 (>30,000 nM). Lowers blood pressure, more potent than Des-Arg9-Bradykinin.Formula:C50H73N13O11Purity:98%Color and Shape:SolidMolecular weight:1032.21MM 07
CAS:Biased agonist for apelin/G protein pathway, enhances eNOS and cell growth, reduces apoptosis, improves heart function, and dilates vessels.Formula:C67H106N22O14S3Purity:98%Color and Shape:SolidMolecular weight:1539.9Pentagastrin meglumine
CAS:Pentagastrin meglumine is a synthetic pentapeptide that has effects like gastrin when given parenterally.Formula:C44H66N8O14SColor and Shape:SolidMolecular weight:963.11Terazosin dimer impurity dihydrochloride
CAS:Terazosin dimer impurity dihydrochloride is a chemical byproduct of the α1-antagonist Terazosin, derived from quinazoline.Formula:C24H30Cl2N8O4Color and Shape:SolidMolecular weight:565.46Carbocyclic Thromboxane A2
CAS:Carbocyclic Thromboxane A2 can be used in related research in the field of life sciences. Its product number is T36548 and CAS number is 74034-56-3.Formula:C22H36O3Color and Shape:SolidMolecular weight:348.527Esprolol
CAS:Esprolol (ACC-9369 free base) is a novel beta-adrenergic antagonist used to study exertional angina.Formula:C17H27NO4Purity:71.58% - 99.16%Color and Shape:SoildMolecular weight:309.4Ref: TM-T27286L
1mg80.00€2mg105.00€5mg172.00€10mg253.00€25mg414.00€50mg583.00€100mg783.00€200mg1,054.00€YM 09538
CAS:YM 09538 is a biochemical.Formula:C18H25ClN2O5SColor and Shape:SolidMolecular weight:416.92ONO-8711
CAS:ONO-8711 is a potent and selective competitive antagonist of EP1 receptor with Kis of 0.6 nM and 1.7 nM for human and mouse EP1, respectively.Formula:C22H30ClNO4SColor and Shape:SolidMolecular weight:440Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.Formula:C22H26FN5OColor and Shape:SolidMolecular weight:395.47Adrogolide HCl
CAS:Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.Formula:C22H26ClNO4SColor and Shape:SolidMolecular weight:435.96MMC(TMZ)-TOC TFA
MMC(TMZ)-TOC TFA exhibits high binding affinity and selectivity for the somatostatin receptor subtype 2 (SSTR2). It targets the delivery of TMZ to SSTR2-positive tumor cells, making MMC(TMZ)-TOC TFA useful for cancer research.Formula:C74H99F3N20O21S2Color and Shape:SolidMolecular weight:1725.82Azepexole hydrochloride
CAS:Azepexole hydrochloride (4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)) is a potent α2-Adrenoceptor agonist with anaestheticFormula:C9H16ClN3OPurity:99.88% - 99.89%Color and Shape:SoildMolecular weight:217.7Antisauvagine-30 TFA
aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).Formula:C163H275N48F3O49SColor and Shape:SolidMolecular weight:3764.28Glucagon-like peptide 1 (1-37), human TFA
Human Glucagon-like peptide 1 (1-37) TFA is a potent GLP-1 receptor agonist derived from proglucagon.Formula:C188H276N51F3O61Purity:98%Color and Shape:SolidMolecular weight:4283.5Neuromedin N
CAS:Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.Formula:C38H63N7O8Purity:98%Color and Shape:SolidMolecular weight:745.95Nadolol
CAS:Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.Formula:C17H27NO4Purity:99.87% - 99.92%Color and Shape:White To Off-White Crystalline Powder SolidMolecular weight:309.40
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