GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(3,031 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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Rimegepant
CAS:View and buy Rimegepant from TargetMol.BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.Cited in 1 publications.Formula:C28H28F2N6O3Purity:99.1% - 99.99%Color and Shape:SolidMolecular weight:534.56C14TKL-1 acetate
C14TKL-1 acetate is a NK1 receptor agonist.Formula:C65H102N20O15S2Purity:98.56%Color and Shape:SolidMolecular weight:1467.75Puerarin
CAS:Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.Formula:C21H20O9Purity:98.90% - 99.21%Color and Shape:Yellow Brown Fine PowderMolecular weight:416.38ML-031
CAS:ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.Formula:C19H20N2O3Purity:99.21%Color and Shape:SolidMolecular weight:324.37Ertugliflozin
CAS:PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).Formula:C22H25ClO7Purity:99.89% - 99.96%Color and Shape:SolidMolecular weight:436.88Eprazinone dihydrochloride
CAS:Eprazinone dihydrochloride (NSC 317935) is a mucolytic with antitussive and mucolytic effect.Formula:C24H32N2O2·2HClPurity:99.25%Color and Shape:A White Or Almost White CrysMolecular weight:453.445'-N-Ethylcarboxamidoadenosine
CAS:NECA, an adenosine receptor agonist, boosts brain extravasation of fluorescein and dextran without affecting the blood-brain barrier.Formula:C12H16N6O4Purity:98.95% - ≥95%Color and Shape:PowderMolecular weight:308.29BAR501
CAS:BAR501是高效选择性的 GPBAR1激动剂(EC50:1 μM)。Formula:C26H46O3Purity:99.29% - 99.68%Color and Shape:SolidMolecular weight:406.64Senktide
CAS:Senktide is an agonist of tachykinin NK3 receptor.Formula:C40H55N7O11SPurity:99.84% - >99.99%Color and Shape:White PowderMolecular weight:841.97Almotriptan Malate
CAS:Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.Formula:C17H25N3O2S·C4H6O5Purity:99.95%Color and Shape:Pale Yellow SolidMolecular weight:469.55Sarpogrelate hydrochloride
CAS:Sarpogrelate hydrochloride (MCI-9042), a 5-HT2 antagonist with high affinity (Ki=8.39nM), is used as an anti-platelet for PAD, improving vascular function.
Formula:C24H32ClNO6Purity:99.73%Color and Shape:Colorless LiquidMolecular weight:465.97Irdabisant hydrochloride
CAS:Irdabisant (CEP-26401) is a selective H3R inverse agonist, BBB-penetrable, with cognition-enhancing effects.Formula:C18H24ClN3O2Color and Shape:SolidMolecular weight:349.86Fluphenazine decanoate
CAS:Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.Formula:C32H44F3N3O2SPurity:98.14%Color and Shape:SolidMolecular weight:591.77Amezinium methylsulfate
CAS:Amezinium methylsulfate (Lu-1631) has multiple mechanisms, including stimulation of α and β-1 receptors and inhibition of noradrenaline and tyramine uptake.Formula:C12H15N3O5SPurity:99.64% - 99.99%Color and Shape:SolidMolecular weight:313.33Fuscoside
CAS:Fuscoside (OPC-21268) is a non-peptide arginine vasopressin (AVP) receptor VI antagonist with an IC50 value of 0.4 μM.Cost-effective and quality-assured.Formula:C26H31N3O4Purity:98.13% - 99.66%Color and Shape:SolidMolecular weight:449.54Xamoterol
CAS:Xamoterol is a cardiac stimulant.Formula:C16H25N3O5Color and Shape:SolidMolecular weight:339.39Terutroban
CAS:Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis.Formula:C20H22ClNO4SPurity:99.53%Color and Shape:SolidMolecular weight:407.91JD-5037
CAS:JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.Formula:C27H27Cl2N5O3SPurity:99.54% - 99.84%Color and Shape:SolidMolecular weight:572.51Ref: TM-T4453
1mg42.00€2mg55.00€5mg90.00€10mg133.00€25mg234.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)101.00€Tetrahydrozoline hydrochloride
CAS:Tetrahydrozoline hydrochloride (Murine Plus) is an imidazoline derivative with alpha receptor agonist activity.Formula:C13H16N2·HClPurity:99.90%Color and Shape:Off-White SolidMolecular weight:236.74PRX-08066
CAS:PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.Formula:C19H17ClFN5SPurity:97.79% - 98.07%Color and Shape:SolidMolecular weight:401.89Ref: TM-T16669
1mg57.00€5mg113.00€10mg166.00€25mg333.00€50mg495.00€100mg710.00€200mg973.00€1mL*10mM (DMSO)105.00€PRX-07034 hydrochloride
CAS:PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and decreases body weight in rodents.Formula:C21H29Cl2N3O4SPurity:98.5%Color and Shape:SolidMolecular weight:490.44Otenabant hydrochloride
CAS:Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).Formula:C25H26Cl3N7OPurity:99.79% - ≥95%Color and Shape:SolidMolecular weight:546.88JNJ-5207852 dihydrochloride
CAS:JNJ-5207852 dihydrochloride is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptorFormula:C20H34Cl2N2OPurity:99.51%Color and Shape:SolidMolecular weight:389.4Exendin-4
CAS:Exenatide: GLP-1 receptor agonist, 39-amino acid, longer half-life (2.4 hrs), IC50 of 3.22 nM.Formula:C184H282N50O60SPurity:97.71% - 99.78%Color and Shape:SolidMolecular weight:4186.57Ozanimod
CAS:Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator.Formula:C23H24N4O3Purity:98.68% - 99.58%Color and Shape:SolidMolecular weight:404.46Ref: TM-T6923
1mg46.00€5mg90.00€10mg137.00€25mg268.00€50mg430.00€100mg622.00€200mg879.00€500mg1,305.00€1mL*10mM (DMSO)90.00€R715 TFA(185052-09-9 free base)
R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49).Formula:C59H82F3N13O14Purity:>99.99%Color and Shape:SolidMolecular weight:1254.36REV 5901
CAS:REV 5901: oral leukotriene receptor antagonist and 5-lipoxygenase inhibitor with Ki of 0.7 μM, researched for asthma.Formula:C22H25NO2Color and Shape:SolidMolecular weight:335.44Pitolisant hydrochloride
CAS:Pitolisant hydrochloride (Ciproxidine) is a potent and selective inverse agonist of the histamine H3 receptor(Ki : 0.16 nM).Formula:C17H27Cl2NOPurity:99.72% - 99.91%Color and Shape:SolidMolecular weight:332.31Ref: TM-T7176
5mg50.00€10mg74.00€25mg124.00€50mg197.00€100mg311.00€200mg467.00€500mg747.00€1mL*10mM (DMSO)52.00€Talastine HCl
CAS:Talastine is an antihistamine drug.Formula:C19H22ClN3OPurity:98%Color and Shape:SolidMolecular weight:343.86Levobetaxolol hydrochloride
CAS:Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride) is a beta blocker, used to lower the pressure in the eye in treating conditions such as glaucoma.Formula:C18H29NO3·HClPurity:98.80% - 99.69%Color and Shape:SolidMolecular weight:343.89Rotigotine-
CAS:Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome.Formula:C19H25NOSPurity:98.08% - 99.59%Color and Shape:SolidMolecular weight:315.47Ref: TM-T6647
5mg50.00€10mg73.00€25mg138.00€50mg241.00€100mg358.00€200mg523.00€500mg822.00€1mL*10mM (DMSO)52.00€DPCPX
CAS:DPCPX (PD 116948) is an A1 adenosine receptor antagonistFormula:C16H24N4O2Purity:99.23% - 99.93%Color and Shape:White SolidMolecular weight:304.399-FLUORENOL
CAS:9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.Formula:C13H10OPurity:99.98%Color and Shape:Off-White Crystalline PowderMolecular weight:182.22Paltusotine
CAS:Paltusotine: nonpeptide SST2 agonist, orally bioavailable, regulates GH/IGF-1 in acromegaly.Formula:C27H22F2N4OPurity:99.91%Color and Shape:SolidMolecular weight:456.49Mequitazine
CAS:Mequitazine (Virginan) is an effective, nonsedative and long-acting histamine H1 antagonist.Formula:C20H22N2SPurity:99.98%Color and Shape:SolidMolecular weight:322.47S26131
CAS:S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) behaves as an antagonist on MT1 and MT2 receptors with Ki ofFormula:C31H34N2O4Purity:99.77%Color and Shape:SolidMolecular weight:498.61RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Formula:C25H20N4O3Purity:98.44% - 99.81%Color and Shape:SolidMolecular weight:424.45Ref: TM-T6634
1mg48.00€5mg92.00€10mg156.00€25mg298.00€50mg472.00€100mg687.00€200mg938.00€1mL*10mM (DMSO)97.00€Bilastine
CAS:Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration ofFormula:C28H37N3O3Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:463.61BAY-545
CAS:BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).Formula:C18H22F3N3O4SPurity:98.05%Color and Shape:SolidMolecular weight:433.45Ref: TM-T8512
1mg84.00€5mg161.00€10mg235.00€25mg420.00€50mg605.00€100mg842.00€200mg1,134.00€1mL*10mM (DMSO)172.00€ML 154
CAS:ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.Formula:C29H26BrN2PSPurity:99.53%Color and Shape:SolidMolecular weight:545.47Pranlukast hemihydrate
CAS:Pranlukast hemihydrate (ONO-1078 hemihydrate) is an LT antagonist with anti-asthmatic activity.Formula:C27H23N5O40·5H2OPurity:99.28%Color and Shape:SolidMolecular weight:490.52Bay 59-3074
CAS:Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM).
Formula:C18H13F6NO4SPurity:97.68% - 99.69%Color and Shape:SolidMolecular weight:453.36Men 10376 TFA(135306-85-3,free)
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4Formula:C59H69F3N12O12Purity:99.22%Color and Shape:SolidMolecular weight:1195.25Galanin (1-16), mouse, porcine, rat
CAS:Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.Formula:C78H116N20O21Purity:98.65%Color and Shape:White PowderMolecular weight:1669.88Adrenocorticotropic Hormone (ACTH) (4-10) TFA
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor .Formula:C46H60F3N13O12SPurity:98.49%Color and Shape:SolidMolecular weight:1076.12Ref: TM-T7627L
1mg54.00€2mg71.00€5mg92.00€10mg152.00€25mg324.00€50mg485.00€100mg620.00€200mg897.00€1mL*10mM (DMSO)202.00€2-ATHBI
CAS:2-ATHBI is a S1P lyase inhibitor.Formula:C9H14N2O5Purity:99.10%Color and Shape:SolidMolecular weight:230.22Haloperidol decanoate
CAS:Haloperidol decanoate (KD 16), an antipsychotic, treats schizophrenia and mood disorders as an intramuscular ester.Formula:C31H41ClFNO3Purity:99.57% - 99.72%Color and Shape:SolidMolecular weight:530.11Ref: TM-T25487
5mg48.00€10mg66.00€25mg117.00€50mg170.00€100mg255.00€200mg373.00€1mL*10mM (DMSO)50.00€SCH-37370
CAS:SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.Formula:C21H21ClN2OPurity:99.07%Color and Shape:SolidMolecular weight:352.86Ref: TM-T19686
1mg48.00€5mg89.00€10mg115.00€25mg195.00€50mg290.00€100mg393.00€200mg520.00€1mL*10mM (DMSO)90.00€Rimcazole dihydrochloride
CAS:Rimcazole dihydrochloride: a σ receptor antagonist, hydrochloride salt, blocks dopamine uptake.Formula:C21H28ClN3Purity:99.63%Color and Shape:SolidMolecular weight:357.92Ref: TM-T23234
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg289.00€50mg470.00€100mg683.00€500mg1,423.00€H2L 5765834
CAS:H2L 5765834 is a lysophosphatidic acid receptors antagonistFormula:C21H12N2O7Purity:98.25% - 99.47%Color and Shape:SolidMolecular weight:404.33Ref: TM-T22834
1mg58.00€5mg113.00€10mg177.00€25mg334.00€50mg497.00€100mg708.00€1mL*10mM (DMSO)124.00€
