GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,030 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(159 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(196 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(55 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5985 products of "GPCR/G-Protein"
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SCH-37370
CAS:SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.Formula:C21H21ClN2OPurity:99.07%Color and Shape:SolidMolecular weight:352.86Ref: TM-T19686
1mg48.00€5mg89.00€10mg115.00€25mg195.00€50mg290.00€100mg393.00€200mg520.00€1mL*10mM (DMSO)90.00€Montelukast sodium
CAS:Montelukast sodium (MK0476), an oral leukotriene antagonist for asthma, can cause rare liver injury.Formula:C35H35ClNNaO3SPurity:99.14% - 99.89%Color and Shape:White To Off-White Crystalline PowderMolecular weight:608.17SRI-37330 hydrochloride
CAS:SRI-37330 hydrochloride is an orally active thioredoxin-interacting protein (TXNIP) inhibitor. hydrochloride can be used to study type 2 diabetes.Formula:C16H20ClF3N4O2SColor and Shape:SolidMolecular weight:424.87RFRP3(human) acetate(311309-27-0 free base)
RFRP-3(human) acetate inhibits gonadotropin, blocks Ca2+ mobilization, acts on NPFF1 receptors, and has an IC50 of 0.7 nM against cAMP production.Formula:C47H76N14O12Purity:97.09%Color and Shape:SolidMolecular weight:1029.19YIL781 hydrochloride
CAS:YIL781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM) with no significant affinity for the motilin receptor (Ki = 6 μM).Formula:C24H29ClFN3O2Color and Shape:SolidMolecular weight:445.96cicloprofen
CAS:cicloprofen is Cell division cycle 7-related protein kinase (human) inhibitor.Formula:C16H14O2Purity:98.15%Color and Shape:SolidMolecular weight:238.2812Ref: TM-T8586
1mg62.00€5mg123.00€10mg180.00€25mg298.00€50mg419.00€100mg567.00€200mg752.00€1mL*10mM (DMSO)111.00€Dexmedetomidine
CAS:Dexmedetomidine: a central alpha-2 adrenergic agonist for general anesthesia.Formula:C13H16N2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:200.28Regadenoson hydrate
CAS:Regadenoson is an A2A adenosine receptor agonist, a coronary vasodilator commonly used in pharmacologic stress testing.Formula:C15H20N8O6Purity:98%Color and Shape:SolidMolecular weight:408.37Ivabradine hydrochloride
CAS:Ivabradine HCl (S 16257-2) is an If inhibitor (IC50: 2.9 μM) and SA node HCN channel blocker that slows heart rate.Formula:C27H37ClN2O5Purity:99% - 99.73%Color and Shape:SolidMolecular weight:505.05Tasimelteon
CAS:Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.Formula:C15H19NO2Purity:98.93% - 99.93%Color and Shape:SolidMolecular weight:245.32Idazoxan hydrochloride
CAS:Idazoxan hydrochloride (RX 781094) is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity.Formula:C11H12N2O2·HClPurity:99.42% - 99.84%Color and Shape:SolidMolecular weight:240.69Ref: TM-T0115
2mg35.00€5mg52.00€10mg78.00€25mg133.00€50mg187.00€100mg281.00€200mg416.00€1mL*10mM (DMSO)50.00€Neuropeptide W-23(human)
CAS:Neuropeptide W-23(human) (NPW-23) is an endogenous ligand for NPBW1 and NPBW2.Formula:C119H183N35O28SPurity:98.5%Color and Shape:SolidMolecular weight:2584.01Ref: TM-TP1073
1mg114.00€2mg177.00€5mg334.00€10mg485.00€25mg770.00€50mg1,035.00€100mg1,395.00€500mg2,673.00€RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purity:98.64% - 99.62%Color and Shape:SolidMolecular weight:417.5Gastrin I (1-14), human
CAS:Gastrin I (1-14), human: a short peptide from the hormone gastrin, which regulates gastric acid secretion.Formula:C79H100N16O27Purity:98.19%Color and Shape:SolidMolecular weight:1705.73Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFormula:C21H32O2Purity:99.59% - 99.92%Color and Shape:SolidMolecular weight:316.48Ref: TM-TN1465
1mg145.00€2mg215.00€5mg314.00€10mg474.00€25mg808.00€50mg1,111.00€100mg1,501.00€1mL*10mM (DMSO)324.00€Fenoprofen Calcium
CAS:Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.Formula:C30H26CaO6Purity:99.24% - 99.66%Color and Shape:SolidMolecular weight:522.6Levobetaxolol hydrochloride
CAS:Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride) is a beta blocker, used to lower the pressure in the eye in treating conditions such as glaucoma.Formula:C18H29NO3·HClPurity:98.80% - 99.69%Color and Shape:SolidMolecular weight:343.89Pimozide
CAS:Pimozide: antipsychotic that blocks type 2 dopamine, alpha-adrenergic, and 5-HT2 receptors, reducing tics and delusions.Formula:C28H29F2N3OPurity:99.63% - >99.99%Color and Shape:SolidMolecular weight:461.55TRAP-6 amide acetate
TRAP-6 amide acetate is a PAR-1 thrombin receptor agonist peptide[1].
Formula:C36H61N11O10Purity:98.55%Color and Shape:SolidMolecular weight:807.94RTICBM-189
CAS:RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay.Formula:C15H14Cl2N2OPurity:99.96%Color and Shape:SolidMolecular weight:309.19Ref: TM-T9466
2mg34.00€5mg52.00€10mg84.00€25mg161.00€50mg250.00€100mg369.00€200mg522.00€1mL*10mM (DMSO)67.00€Cyclopiazonic acid
CAS:Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.Formula:C20H20N2O3Purity:99.27% - 99.80%Color and Shape:SolidMolecular weight:336.38SB756050
CAS:SB756050 is a specific TGR5 agonist.Formula:C21H28N2O8S2Purity:98.78% - >99.99%Color and Shape:SolidMolecular weight:500.59ENMD-1068 HBr
CAS:ENMD-1068 HBr is a novel Proteinase-Activated Receptor 2 antagonist.Formula:C15H30BrN3O2Color and Shape:SolidMolecular weight:364.32Afamelanotide acetate
CAS:Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist.
Formula:C80H115N21O21Purity:98% - 99.494%Color and Shape:SolidMolecular weight:1706.9Naftopidil hydrochloride
CAS:Naftopidil HCl (BM-15275) is a selective alpha1 blocker with Ki: α1a-3.7 nM, α1b-20 nM, α1d-1.2 nM; it also inhibits cell growth.Formula:C24H29ClN2O3Purity:99.5%Color and Shape:SolidMolecular weight:428.95Ref: TM-T9220
1mg44.00€5mg87.00€10mg117.00€25mg202.00€50mg304.00€100mg437.00€200mg612.00€1mL*10mM (DMSO)97.00€Bevantolol hydrochloride
CAS:Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.Formula:C20H28ClNO4Purity:99.49%Color and Shape:SolidMolecular weight:381.9ML-193
CAS:ML-193: GPR55 antagonist, IC50 221nM, 27x selective over GPR35/CB1/CB2, may aid Parkinson's symptoms.Formula:C28H25N5O4SPurity:97.74%Color and Shape:SolidMolecular weight:527.59Neurokinin A(4-10) TFA(97559-35-8 free base)
Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].Formula:C36H55F3N8O12SPurity:>99.99%Color and Shape:SolidMolecular weight:880.93Tripelennamine citrate
CAS:Tripelennamine citrate, an ethylenediamine derivative, blocks H1 receptors to treat allergies and anaphylaxis.Formula:C22H29N3O7Color and Shape:SolidMolecular weight:447.488Tecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFormula:C18H22ClNOColor and Shape:SolidMolecular weight:303.83Dolasetron Mesylate hydrate
CAS:Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.Formula:C20H26N2O7SPurity:99.86% - 99.99%Color and Shape:SolidMolecular weight:438.49Naratriptan
CAS:Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.Formula:C17H25N3O2SPurity:99.08%Color and Shape:SolidMolecular weight:335.47Ref: TM-T8666
1mg42.00€2mg52.00€5mg77.00€10mg97.00€25mg170.00€50mg254.00€100mg380.00€1mL*10mM (DMSO)93.00€LY2828360
CAS:LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.Formula:C22H27ClN6OPurity:98.45% - 99.51%Color and Shape:SolidMolecular weight:426.94FAUC 213
CAS:FAUC 213 is a selective full antagonist of the dopamine D4 receptor.Formula:C18H19ClN4Purity:99.84%Color and Shape:SolidMolecular weight:326.82SCH442416
CAS:SCH442416: selective A2A adenosine receptor antagonist; Ki: 0.048 nM (human), 0.5 nM (rat).
Formula:C20H19N7O2Purity:99.58%Color and Shape:SolidMolecular weight:389.41Darusentan
CAS:Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteriesFormula:C22H22N2O6Purity:98.72%Color and Shape:SolidMolecular weight:410.43Ref: TM-T5458
2mg46.00€5mg69.00€10mg105.00€25mg183.00€50mg304.00€100mg437.00€200mg615.00€1mL*10mM (DMSO)71.00€BMY-25368
CAS:BMY-25368 is a long-acting antagonist of the H2-receptor.Formula:C19H25N3O3Color and Shape:SolidMolecular weight:343.42ML 154
CAS:ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.Formula:C29H26BrN2PSPurity:99.53%Color and Shape:SolidMolecular weight:545.47Fluoroclebopride
CAS:Fluoroclebopride is a dopamine (DA) D2 receptor ligand.Formula:C20H23ClFN3O2Purity:99.68% - 99.91%Color and Shape:SolidMolecular weight:391.87Ref: TM-T3187
1mg35.00€5mg74.00€10mg96.00€25mg159.00€50mg235.00€100mg376.00€500mg867.00€1mL*10mM (DMSO)96.00€GRK5-IN-2
CAS:GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.Formula:C20H20N4O4Purity:99.92%Color and Shape:SolidMolecular weight:380.4Ref: TM-T9609
2mg35.00€5mg50.00€10mg80.00€25mg145.00€50mg226.00€100mg335.00€200mg469.00€1mL*10mM (DMSO)55.00€Mebhydrolin
CAS:Mebhydrolin (Mebhydroline) is a specific histamine H1 receptor antagonist.Formula:C19H20N2Purity:99.3% - ≥98%Color and Shape:SolidMolecular weight:276.38BisfluoroModafinil
CAS:CRL-40940 is a selective dopaminergic reuptake inhibitorFormula:C15H13F2NO2SPurity:99.19%Color and Shape:SolidMolecular weight:309.33NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Formula:C19H21N3OPurity:97.13%Color and Shape:SolidMolecular weight:307.39Ref: TM-T8457
5mg42.00€10mg64.00€25mg111.00€50mg187.00€100mg306.00€200mg423.00€1mL*10mM (DMSO)To inquireZafirlukast
CAS:Zafirlukast (ICI 204219) is an orally leukotriene D4 receptor (LTD4) antagonist. Zafirlukast has anti-asthmatic and anti-inflammatory effects. Cost-effective and quality-assured.Formula:C31H33N3O6SPurity:99% - 99.83%Color and Shape:SolidMolecular weight:575.68Cerlapirdine
CAS:Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.Formula:C22H23N3O3SPurity:98.77%Color and Shape:SolidMolecular weight:409.5Ref: TM-T30798
1mg81.00€5mg170.00€10mg274.00€25mg543.00€50mg780.00€100mg1,074.00€1mL*10mM (DMSO)198.00€LY310762
CAS:LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM.Formula:C24H27FN2O2·HClPurity:99.8%Color and Shape:SolidMolecular weight:430.94CAY10526
CAS:CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.Formula:C12H7BrO3SPurity:98.75%Color and Shape:SolidMolecular weight:311.15Blarcamesine hydrochloride
CAS:Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).Formula:C19H24ClNOPurity:99.57% - 99.9%Color and Shape:SolidMolecular weight:317.85Ref: TM-T4111
1mg35.00€2mg48.00€5mg70.00€10mg104.00€25mg207.00€50mg359.00€100mg588.00€200mg833.00€1mL*10mM (DMSO)78.00€Pramlintide acetate(151126-32-8 free base)
CAS:Pramlintide acetate is a polypeptide analogue of human amylin. It serves as an antidiabetic agent and exhibits antineoplastic activity in colorectal cancer.Formula:C173H271N51O55S2Purity:>99.99%Color and Shape:SolidMolecular weight:4009Liraglutide
CAS:Liraglutide (Liraglutida) is a synthetic analog of GLP-1, an agonist of the GLP-1 receptor. Liraglutide is an antidiabetic agent. Cost effective and quality assured.Formula:C172H265N43O51Purity:97.65% - 99.04%Color and Shape:SolidMolecular weight:3751.25Ref: TM-T6876
1mg111.00€2mg197.00€5mg447.00€10mg527.00€25mg843.00€50mg1,144.00€100mg1,521.00€200mg2,052.00€
