
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,003 products)
- Adenosine Receptor(247 products)
- Adrenergic Receptor(3,010 products)
- Bombesin Receptor(33 products)
- Bradykinin Receptor(60 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(215 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(435 products)
- Endothelin Receptor(83 products)
- GNRH Receptor(82 products)
- GPCR19(33 products)
- GRK(32 products)
- GTPase(22 products)
- Glucagon Receptor(190 products)
- Hedgehog/Smoothened(48 products)
- Histamine Receptor(381 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(321 products)
- PAFR(13 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5838 products of "GPCR/G-Protein"
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Clobenpropit 2HBr
CAS:Clobenpropit 2HBr is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain.Formula:C14H17ClN4SColor and Shape:SolidMolecular weight:308.83L-DOPA methyl ester (hydrochloride)
CAS:<p>L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.</p>Formula:C10H14ClNO4Purity:98.69% - 99.81%Color and Shape:White SolidMolecular weight:247.675Phentolamine
CAS:Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonistFormula:C17H19N3OPurity:99.86% - 99.94%Color and Shape:Crystals SolidMolecular weight:281.35Fluparoxan HCl
CAS:<p>Fluparoxan is a potent α2-adrenergic receptor antagonist (pKB = 7.9) with excellent α2/α1 selectivity (2630 fold).</p>Formula:C10H11ClFNO2Color and Shape:SolidMolecular weight:231.65Vilanterol trifenatate
CAS:Vilanterol trifenatate is a long-acting agonist of β2-adrenoceptor (β2-AR) with inherent 24-hour activity(β2-AR, β1-AR and β3-AR pEC50s of 10.37, 6.98 and 7.36, respectively)Formula:C44H49Cl2NO7Purity:99.51% - >99.99%Color and Shape:SolidMolecular weight:774.77BGC-20-1531 hydrochloride(1186532-61-5 free base)
CAS:<p>BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine.</p>Formula:C26H25ClN2O6SPurity:98.94% - 99.85%Color and Shape:SolidMolecular weight:529Bromodiphenhydramine hydrochloride
CAS:<p>Bromodiphenhydramine hydrochloride is a new antihistaminic in the control of cutaneous.</p>Formula:C17H21BrClNOPurity:97.29%Color and Shape:SolidMolecular weight:370.71Benzotript
CAS:<p>Benzotript is an gastrin-receptor antagonist, with anti-gastrinic.</p>Formula:C18H15ClN2O3Purity:97.82%Color and Shape:SolidMolecular weight:342.776Nonapeptide-1
CAS:Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.Formula:C61H87N15O9SPurity:100%Color and Shape:SolidMolecular weight:1206.5Xanthine amine congener hydrochloride
CAS:Xanthine amine congener (XAC) hydrochloride is a non-selective adenosine receptor antagonist that induces convulsions in mice.Formula:C21H29ClN6O4Color and Shape:SolidMolecular weight:464.95ACTH 1-14 acetate(25696-21-3 free base)
<p>ACTH 1-14 acetate regulates cortisol and androgen, is part of the hypothalamic-pituitary-adrenal stress response.</p>Formula:C79H113N21O22SPurity:>99.99%Color and Shape:SolidMolecular weight:1740.96Ambrisentan sodium
CAS:<p>Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).</p>Formula:C22H21N2NaO4Color and Shape:SolidMolecular weight:400.41LM11A-31 dihydrochloride
CAS:LM11A-31 dihydrochloride is a water-soluble, BBB-penetrating p75NTR ligand and proNGF antagonist.Formula:C12H27Cl2N3O2Purity:99.9%Color and Shape:SolidMolecular weight:316.27SCH-37370
CAS:<p>SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.</p>Formula:C21H21ClN2OPurity:99.07%Color and Shape:SolidMolecular weight:352.86Zuclopenthixol dihydrochloride
CAS:Zuclopenthixol dihydrochloride is an D1 and D2 dopamine receptors antagonist.Formula:C22H27Cl3N2OSPurity:98%Color and Shape:SolidMolecular weight:473.89Icatibant Acetate
CAS:Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.Formula:C61H93N19O15SPurity:99.68% - 99.90%Color and Shape:SolidMolecular weight:1364.57MK-2894 sodium salt
CAS:MK-2894 sodium salt is a highly potent and selective antagonist of second generation EP4.Formula:C25H22F3NNaO3SPurity:98%Color and Shape:SolidMolecular weight:496.5Terazosin
CAS:Terazosin: oral α1-blocker, relaxes blood vessels, treats BPH and hypertension.Formula:C19H25N5O4Color and Shape:SolidMolecular weight:387.43Melanotan I
CAS:Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an α-melanocyte-stimulating hormone (α-MSH) analog, which is injected subcutaneously toFormula:C78H111N21O19Purity:>99.99%Color and Shape:SolidMolecular weight:1646.85Ambrisentan
CAS:<p>Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.</p>Formula:C22H22N2O4Purity:99.65% - 99.86%Color and Shape:SolidMolecular weight:378.42Emedastine
CAS:<p>Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.</p>Formula:C17H26N4OPurity:97.1% - 97.76%Color and Shape:OilMolecular weight:302.41Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Formula:C36H47ClN8O3Purity:98.93%Color and Shape:SolidMolecular weight:675.3LUN42518 HCl 47142-51-8(free base)
<p>LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.</p>Formula:C17H20ClN3OPurity:99.96%Color and Shape:SolidMolecular weight:317.81Eltoprazine
CAS:Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.Formula:C12H16N2O2Color and Shape:SolidMolecular weight:220.27EST64454 hydrochloride
CAS:EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.Formula:C18H23ClF2N4O2Purity:99.15%Color and Shape:SolidMolecular weight:400.85Dobutamine
CAS:Dobutamine, a synthetic catecholamine, boosts cardiac output and improves blood flow, mainly targeting β1-AR.Formula:C18H23NO3Color and Shape:SolidMolecular weight:301.38Cimetidine hydrochloride
CAS:Cimetidine (SKF-92334) is an oral H2 blocker with Ki 0.6 μM, anti-cancer and anti-inflammatory properties, used for ulcer research.Formula:C10H17ClN6SColor and Shape:SolidMolecular weight:288.8ML-18
CAS:ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.Formula:C32H35N5O5Purity:98.62% - >99.99%Color and Shape:SolidMolecular weight:569.65Men 10376 TFA(135306-85-3,free)
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4Formula:C59H69F3N12O12Purity:99.22%Color and Shape:SolidMolecular weight:1195.25Lidamidine Hydrochloride
CAS:Lidamidine HCl: α2-adrenergic agonist; lowers gut secretion, slows transit, stops muscle contractions.Formula:C11H17ClN4OColor and Shape:SolidMolecular weight:256.73Temanogrel
CAS:<p>Temanogrel (APD791) is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).</p>Formula:C24H28N4O4Purity:99.24%Color and Shape:SolidMolecular weight:436.52'-O-Methylisoliquiritigenin
CAS:2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-Formula:C16H14O4Purity:98.75%Color and Shape:SolidMolecular weight:270.28Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColor and Shape:SolidMolecular weight:467.92Phentolamine hydrochloride
CAS:Phentolamine hydrochloride is a blocking agent of adrenergic α receptor that is orally active [1].Formula:C17H20ClN3OColor and Shape:SolidMolecular weight:317.82Ziprasidone mesylate
CAS:Ziprasidone mesylate (CP-88059), an oral 5-HT & dopamine blocker, binds D2, 5-HT2A, 5-HT1A with Ki values: 4.8, 0.42, 3.4 nM.Formula:C22H25ClN4O4S2Color and Shape:SolidMolecular weight:509.04ENMD-1068 HBr
CAS:ENMD-1068 HBr is a novel Proteinase-Activated Receptor 2 antagonist.Formula:C15H30BrN3O2Color and Shape:SolidMolecular weight:364.32Nifenalol
CAS:Nifenalol is an adrenergic beta-blocker with good antiarrhythmic properties. It tends to lower blood pressure and provide protection against angina.Formula:C11H16N2O3Purity:98%Color and Shape:SolidMolecular weight:224.26Syk Inhibitor II dihydrochloride dihydrate
CAS:Potent, selective ATP-competitive Syk Inhibitor II (IC50: 41 nM), with anti-allergic properties, in dihydrochloride dihydrate form.Formula:C14H21Cl2F3N6O3Color and Shape:SolidMolecular weight:449.26Cinaciguat hydrochloride
CAS:Cinaciguat( BAY582667, BAY58-2667) is a soluble guanosine cyclase activator that can prevent cardiac dysfunction in rat models of type 1 diabetes.Formula:C36H40ClNO5Color and Shape:SolidMolecular weight:602.17Risperidone hydrochloride
CAS:Risperidone hydrochloride blocks 5-HT2, inhibits P-glycoprotein, and antagonizes D2 receptors (Ki: 5-HT2A - 4.8 nM, D2 - 5.9 nM).Formula:C23H28ClFN4O2Color and Shape:SolidMolecular weight:446.95Cinanserin
CAS:Cinanserin is a serotonin 5-HT2 antagonist.Formula:C20H24N2OSColor and Shape:SolidMolecular weight:340.48Alosetron (Hydrochloride(1:X))
CAS:<p>Alosetron Hydrochloride is a selective 5-HT3 antagonist for treating IBS.</p>Formula:C17H18ClN4OColor and Shape:SolidMolecular weight:329.11691Laropiprant sodium
<p>Laropiprant sodium is a potent and selective DP receptor antagonist with Ki values of 0.57 nM for TP receptors and 2.95 nM for DP receptors.</p>Color and Shape:SolidApraclonidine
CAS:Apraclonidine (ALO 2145), an α2/weak α1 agonist, lowers IOP; used as eye drops.Formula:C9H10Cl2N4Color and Shape:SolidMolecular weight:245.11Napitane Mesylate
CAS:Napitane Mesylate inhibits norepinephrine transporter and blocks CNS CA uptake as an alpha 2-adrenoceptor antagonist.Formula:C23H29NO5SPurity:98%Color and Shape:SolidMolecular weight:431.55S 14506 HCl
CAS:S 14506 HCl: Strong 5-HT1A agonist; pKi - 9.0 (5-HT1A), 6.6 (5-HT1B/C), <6.0 (5-HT3).Formula:C24H26FN3O2Color and Shape:SolidMolecular weight:407.48PD 168568
CAS:PD 168568: Oral DRD4 antagonist, selective over D2/D3, K_i - 8.8 nM. Used in GBM research.Formula:C22H27N3OColor and Shape:SolidMolecular weight:349.47Xamoterol
CAS:Xamoterol is a cardiac stimulant.Formula:C16H25N3O5Color and Shape:SolidMolecular weight:339.39T-1095
CAS:T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Formula:C26H28O11Purity:99.78%Color and Shape:SolidMolecular weight:516.49Regadenoson hydrate
CAS:Regadenoson is an A2A adenosine receptor agonist, a coronary vasodilator commonly used in pharmacologic stress testing.Formula:C15H20N8O6Purity:98%Color and Shape:SolidMolecular weight:408.37

