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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5838 products of "GPCR/G-Protein"

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  • Neuropeptide SF(mouse,rat) acetate
    Targetmol
    + Info

    Neuropeptide SF(mouse,rat) acetate

    Neuropeptide SF (mouse,rat) acetate is a NPFF receptor agonist with Ki of 48.4 nM (NPFF1) & 12.1 nM (NPFF2), enhancing ASIC3 current.
    Formula:C42H69N13O12
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:948.08

    Ref: TM-TP1884L1

  • BPTU
    Targetmol
    + Info

    BPTU

    CAS:
    <p>BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM).</p>
    Formula:C23H22F3N3O3
    Purity:99.37% - 99.89%
    Color and Shape:Solid
    Molecular weight:445.43

    Ref: TM-T4132

  • Siponimod hemifumarate
    Targetmol
    + Info

    Siponimod hemifumarate

    CAS:
    Siponimod (BAF-312) is a potent S1P receptor modulator for multiple sclerosis research.
    Formula:C62H74F6N4O10
    Color and Shape:Solid
    Molecular weight:1149.282

    Ref: TM-T64065

  • Ki16425
    Targetmol
    + Info

    Ki16425

    CAS:
    Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
    Formula:C23H23ClN2O5S
    Purity:97.6% - 97.78%
    Color and Shape:Solid
    Molecular weight:474.96

    Ref: TM-T6108

  • Zatebradine
    Targetmol
    + Info

    Zatebradine

    CAS:
    Zatebradine is a potent hyperpolarization-activated cyclic nucleotide-gated (HCN) channels inhibitor(IC50 of 1.96 μM).
    Formula:C26H36N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:456.57

    Ref: TM-T13387

  • Carbazochrome
    Targetmol
    + Info

    Carbazochrome

    CAS:
    <p>Carbazochrome (Adchnon) is an antihemorrhagic that promotes platelet aggregation to stop bleeding, possibly for surgeries and hemorrhoids treatment.</p>
    Formula:C10H12N4O3
    Purity:98.36%
    Color and Shape:Nacarat Crystalline Powder
    Molecular weight:236.23

    Ref: TM-T3616

  • CGP71683 hydrochloride
    Targetmol
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    CGP71683 hydrochloride

    CAS:
    CGP71683 hydrochloride: NPY5 receptor antagonist, Ki=1.3 nM; inactive at Y1 (Ki >4000 nM) and Y2 (Ki=200 nM).
    Formula:C26H30ClN5O2S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:512.07

    Ref: TM-T5587

  • Albiglutide TFA (782500-75-8 free base)
    Targetmol
    + Info

    Albiglutide TFA (782500-75-8 free base)

    <p>Albiglutide TFA (782500-75-8 free base) (Albiglutide TFA) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM).</p>
    Formula:C150H225F3N40O47
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:3397.63

    Ref: TM-TP1796

  • Quipazine maleate
    Targetmol
    + Info

    Quipazine maleate

    CAS:
    Quipazine maleate is a 5-HT agonist affecting L-02 hepatocytes and raphe neurons, causing smooth muscle contracture and bronchospasm.
    Formula:C17H19N3O4
    Color and Shape:Solid
    Molecular weight:329.356

    Ref: TM-T71792

  • Fenspiride
    Targetmol
    + Info

    Fenspiride

    CAS:
    <p>Fenspiride: oral non-steroidal anti-inflammatory, treats respiratory infections/otitis, inhibits H1-histamine receptors and PDE 3, 4, 5.</p>
    Formula:C15H20N2O2
    Color and Shape:Solid
    Molecular weight:260.33

    Ref: TM-T60417

  • CJC-1295 acetate(863288-34-0 free base)
    Targetmol
    + Info

    CJC-1295 acetate(863288-34-0 free base)

    CJC-1295 acetate is a synthetic GHRH analogue and GHS.
    Formula:C154H256N44O44
    Purity:97.29%
    Color and Shape:Solid
    Molecular weight:3428.01

    Ref: TM-TP2328L

  • Lidamidine Hydrochloride
    Targetmol
    + Info

    Lidamidine Hydrochloride

    CAS:
    Lidamidine HCl: α2-adrenergic agonist; lowers gut secretion, slows transit, stops muscle contractions.
    Formula:C11H17ClN4O
    Color and Shape:Solid
    Molecular weight:256.73

    Ref: TM-T27829

  • Desvenlafaxine succinate hydrate
    Targetmol
    + Info

    Desvenlafaxine succinate hydrate

    CAS:
    Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
    Formula:C20H33NO7
    Purity:99.26%
    Color and Shape:White Crystalline Powde
    Molecular weight:399.48

    Ref: TM-T6188

  • Sarpogrelate
    Targetmol
    + Info

    Sarpogrelate

    CAS:
    Sarpogrelate (MCI-9042), an oral 5-HT2 antagonist, boosts platelet aggregation and aids in studying Buerger's disease.
    Formula:C24H31NO6
    Color and Shape:Solid
    Molecular weight:429.51

    Ref: TM-T62374

  • SSR240612
    Targetmol
    + Info

    SSR240612

    CAS:
    SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors,
    Formula:C42H53ClN4O7S
    Purity:98.59% - 99.16%
    Color and Shape:Solid
    Molecular weight:793.41

    Ref: TM-T5048

  • CP 376395
    Targetmol
    + Info

    CP 376395

    CAS:
    CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
    Formula:C21H30N2O
    Purity:99.86% - 99.94%
    Color and Shape:Solid
    Molecular weight:326.48

    Ref: TM-T4329

  • Tolazoline
    Targetmol
    + Info

    Tolazoline

    CAS:
    <p>Tolazoline (Benzalolin), a vasodilator, treats vessel spasms and reverses 5-HT2A drug overdose effects.</p>
    Formula:C10H12N2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:160.22

    Ref: TM-T21447

  • Clomipramine
    Targetmol
    + Info

    Clomipramine

    CAS:
    <p>Clomipramine treats OCD, depression, chronic pain, and may lower suicide risk in seniors; works by hindering serotonin reuptake.</p>
    Formula:C19H23ClN2
    Purity:99.31% - 99.71%
    Color and Shape:Solid
    Molecular weight:314.85

    Ref: TM-T21013

  • Brimonidine Tartrate
    Targetmol
    + Info

    Brimonidine Tartrate

    CAS:
    Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM).
    Formula:C15H16BrN5O6
    Purity:99.95%
    Color and Shape:Off-White Crystalline Solid
    Molecular weight:442.22

    Ref: TM-T6422

  • Substance P 1-9 aceate
    Targetmol
    + Info

    Substance P 1-9 aceate

    Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.
    Formula:C54H81N15O14
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:1164.31

    Ref: TM-TP1819L

  • ESI-09
    Targetmol
    + Info

    ESI-09

    CAS:
    ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.
    Formula:C16H15ClN4O2
    Purity:97.24% - 99.57%
    Color and Shape:Solid
    Molecular weight:330.77

    Ref: TM-T2244

  • Olcegepant
    Targetmol
    + Info

    Olcegepant

    CAS:
    Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4
    Formula:C38H47Br2N9O5
    Purity:96.08% - 97.24%
    Color and Shape:Solid
    Molecular weight:869.65

    Ref: TM-T12293L

  • Protease-Activated Receptor-1, PAR-1 Agonist acetate
    Targetmol
    + Info

    Protease-Activated Receptor-1, PAR-1 Agonist acetate

    PAR-1 Agonist acetate is a selective PAR-1 agonist that mimics thrombin action.
    Formula:C37H62N10O11
    Purity:98.1800%
    Color and Shape:Solid
    Molecular weight:822.95

    Ref: TM-T38836L

  • Sigma-LIGAND-1 hydrochloride
    Targetmol
    + Info

    Sigma-LIGAND-1 hydrochloride

    CAS:
    <p>Sigma-LIGAND-1 HCl: selective sigma receptor ligand; DTG IC50: 16 nM, PPP IC50: 19 nM; weak D2 receptor affinity, Ki: 4000 nM.</p>
    Formula:C27H34ClNO4
    Color and Shape:Solid
    Molecular weight:472.02

    Ref: TM-T63048

  • RG7713
    Targetmol
    + Info

    RG7713

    CAS:
    <p>RG7713 (RO 5028442) has been used in trials studying Autistic Disorder.</p>
    Formula:C25H28ClN3O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:437.96

    Ref: TM-T4141

  • Volinanserin
    Targetmol
    + Info

    Volinanserin

    CAS:
    Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.
    Formula:C22H28FNO3
    Purity:98.94% - 99.95%
    Color and Shape:Solid
    Molecular weight:373.46

    Ref: TM-T5389

  • Betahistine EP Impurity C
    Targetmol
    + Info

    Betahistine EP Impurity C

    CAS:
    <p>Betahistine EP Impurity C (NSC19005) is structurally related to Betahistine. Betahistine EP Impurity C is a dimer of Betahistine.</p>
    Formula:C15H19N3
    Purity:≥95%
    Color and Shape:Solid
    Molecular weight:241.33

    Ref: TM-T4196

  • Enprofylline
    Targetmol
    + Info

    Enprofylline

    CAS:
    <p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>
    Formula:C8H10N4O2
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:194.19

    Ref: TM-T21389

  • Moxisylyte
    Targetmol
    + Info

    Moxisylyte

    CAS:
    Moxisylyte (thymoxamine) treats erectile dysfunction, Reynaud's syndrome, and reverses eye mydriasis; it's an α1-adrenergic blocker.
    Formula:C16H25NO3
    Color and Shape:Solid
    Molecular weight:279.37

    Ref: TM-T69127

  • KB-5492 anhydrous
    Targetmol
    + Info

    KB-5492 anhydrous

    CAS:
    KB 5492 is an agent of anti-ulcer. It preventing cysteamine-induced duodenal ulcers by stimulating duodenal HCO3- secretion.
    Formula:C27H34N2O10
    Color and Shape:Solid
    Molecular weight:546.57

    Ref: TM-T24254

  • Niaprazine
    Targetmol
    + Info

    Niaprazine

    CAS:
    <p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>
    Formula:C20H25FN4O
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:356.44

    Ref: TM-T36949

  • MK-3697
    Targetmol
    + Info

    MK-3697

    CAS:
    <p>MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).</p>
    Formula:C23H21N5O3S
    Purity:97.69% - 98.15%
    Color and Shape:Solid
    Molecular weight:447.51

    Ref: TM-T1913

  • Selexipag
    Targetmol
    + Info

    Selexipag

    CAS:
    Selexipag (ACT-293987, NS-304) is a drug for PAH that dilates pulmonary vessels.
    Formula:C26H32N4O4S
    Purity:99.98% - >99.99%
    Color and Shape:Solid
    Molecular weight:496.62

    Ref: TM-T3216

  • [Des-Arg9]-Bradykinin TFA
    Targetmol
    + Info

    [Des-Arg9]-Bradykinin TFA

    CAS:
    [Des-Arg9]-Bradykinin is an agonist of Bradykinin (B1) receptor that displays selectivity for B1 over B2 receptors.
    Formula:C46H62F3N11O12
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:1018.05

    Ref: TM-T8809

  • AZD4635
    Targetmol
    + Info

    AZD4635

    CAS:
    AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
    Formula:C15H11ClFN5
    Purity:99.15% - 99.90%
    Color and Shape:Solid
    Molecular weight:315.73

    Ref: TM-T4265

  • Etilevodopa hydrochloride
    Targetmol
    + Info

    Etilevodopa hydrochloride

    CAS:
    Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.
    Formula:C11H16ClNO4
    Purity:95.00%
    Color and Shape:Solid
    Molecular weight:261.7

    Ref: TM-T24047

  • Pizuglanstat
    Targetmol
    + Info

    Pizuglanstat

    CAS:
    Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor.
    Formula:C27H36N6O4
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:508.61

    Ref: TM-T8883

  • RVD-Hpα acetate(1193362-76-3 free base)
    Targetmol
    + Info

    RVD-Hpα acetate(1193362-76-3 free base)

    <p>RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>
    Formula:C67H109N19O19
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:1484.71

    Ref: TM-TP1939L1

  • BIM-23190 aceate
    Targetmol
    + Info

    BIM-23190 aceate

    <p>BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.</p>
    Formula:C59H83N13O14S2
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:1262.5

    Ref: TM-T39262L

  • ELA-14(human) acetate
    Targetmol
    + Info

    ELA-14(human) acetate

    <p>ELA-14(human) acetate, a fragment of ELA, targets APJ, activates Gαi1 and β-arrestin-2, and prompts receptor internalization like its parent peptide.</p>
    Formula:C77H123N25O19S2
    Purity:97.2%
    Color and Shape:Solid
    Molecular weight:1767.09

    Ref: TM-TP1923L1

  • Droxidopa hydrochloride
    Targetmol
    + Info

    Droxidopa hydrochloride

    CAS:
    Droxidopa (L-DOPS) HCI is an oral norepinephrine precursor for nOH and ADHD research, raising standing BP and easing orthostatic hypotension.
    Formula:C9H12ClNO5
    Color and Shape:Solid
    Molecular weight:249.65

    Ref: TM-T60369

  • Cannabigerol
    Targetmol
    + Info

    Cannabigerol

    CAS:
    Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also
    Formula:C21H32O2
    Purity:99.59% - 99.92%
    Color and Shape:Solid
    Molecular weight:316.48

    Ref: TM-TN1465

  • Relenopride hydrochloride
    Targetmol
    + Info

    Relenopride hydrochloride

    CAS:
    Relenopride, a 5-HT agonist, is used potentially for the treatment of chronic constipation.
    Formula:C24H31Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:529.43

    Ref: TM-T28512

  • Trazodone
    Targetmol
    + Info

    Trazodone

    CAS:
    <p>Trazodone (AF-1161), a 5-HT 2A/2C receptor antagonist, is used as an antidepressant for treating major anxiety disorders and depressive disorder.</p>
    Formula:C19H22ClN5O
    Purity:99.79% - 99.92%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:371.86

    Ref: TM-T22442

  • LP-211
    Targetmol
    + Info

    LP-211

    CAS:
    LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
    Formula:C30H34N4O
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:466.62

    Ref: TM-T5387

  • Desipramine
    Targetmol
    + Info

    Desipramine

    CAS:
    <p>Desipramine: tricyclic antidepressant that blocks norepinephrine reuptake and helps reduce sleep-related pharyngeal collapsibility.</p>
    Formula:C18H22N2
    Color and Shape:Solid
    Molecular weight:266.38

    Ref: TM-T60445

  • JNJ-7777120
    Targetmol
    + Info

    JNJ-7777120

    CAS:
    JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist, exhibits >1000-fold selectivity over the other histamin receptors.
    Formula:C14H16ClN3O
    Purity:99.83% - 99.96%
    Color and Shape:Solid
    Molecular weight:277.75

    Ref: TM-T2232

  • JD-5037
    Targetmol
    + Info

    JD-5037

    CAS:
    JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.
    Formula:C27H27Cl2N5O3S
    Purity:99.54% - 99.84%
    Color and Shape:Solid
    Molecular weight:572.51

    Ref: TM-T4453

  • Liraglutide
    Targetmol
    + Info

    Liraglutide

    CAS:
    <p>Liraglutide (Liraglutida) is a synthetic analog of GLP-1, an agonist of the GLP-1 receptor. Liraglutide is an antidiabetic agent. Cost effective and quality assured.</p>
    Formula:C172H265N43O51
    Purity:97.65% - 99.04%
    Color and Shape:Solid
    Molecular weight:3751.25

    Ref: TM-T6876

  • Melanin Concentrating Hormone, salmon acetate
    Targetmol
    + Info

    Melanin Concentrating Hormone, salmon acetate

    Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.
    Formula:C91H143N27O26S4
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:2157

    Ref: TM-TP1104L