GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,018 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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Hedgehog Antagonist VIII
CAS:Hh antagonist VIII is a quinazolinyl-urea that inhibits Gli transcription in the Hh pathway, linked to cancer, with an IC50 of 70 nM.Formula:C23H15ClF4N4O2Color and Shape:SolidMolecular weight:490.84RS 79948 hydrochloride
CAS:α2-adrenoreceptor antagonistFormula:C19H29ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:400.96CAY10535
CAS:CAY10535 is a selective TPβ antagonist (IC50 = 99 nM for TPβ vs 1970 nM for TPα), weakly affects platelets (IC50 = 985 nM).Formula:C18H21N3O7SColor and Shape:SolidMolecular weight:423.444-Chloro Trazodone hydrochloride
CAS:4-Chloro Trazodone HCl is a Trazodone isomer, an antidepressant for anxiety disorders.Formula:C19H23Cl2N5OColor and Shape:SolidMolecular weight:408.32Noberastine maleate
CAS:Noberastine maleate, a fast-acting furan-derived H1 antagonist, peaks at 4 hours with minimal CNS effects and maximal efficacy at 30 mg/day.Formula:C25H29N5O9Color and Shape:SolidMolecular weight:543.53ASP1126
CAS:ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist (EC50s: 7.12 nM, 517 nM for hS1P1 and hS1P3).Formula:C26H26ClF6NO5Purity:98%Color and Shape:SolidMolecular weight:581.93Fertirelin acetate
CAS:Fertirelin acetate is a gonadotropin-releasing hormone (GnRH) agonist.Formula:C55H74N16O13Color and Shape:SolidMolecular weight:1167.29S-14671
CAS:S-14671: 5-HT1A agonist (pKi 9.3), potent in vivo; 5-HT2A/2C antagonist (pKi 7.8).Formula:C22H25N3O2SColor and Shape:SolidMolecular weight:395.52Anitrazafen
CAS:Anitrazafen is a locally effective anti-inflammatory agent that has been shown to have COX-2 inhibitor activity.Formula:C18H17N3O2Purity:98%Color and Shape:SolidMolecular weight:307.35LY 225910
CAS:LY 225910 is a CCK2 receptor antagonist.Formula:C27H24BrN3O2Purity:98%Color and Shape:SolidMolecular weight:502.4Q8 hydrochloride
CAS:Q8 is an antagonist of cysteinyl leukotreine receptor. Q8 inhibits VEGF-independent angiogenesis.Formula:C17H14ClNO2Purity:98%Color and Shape:SolidMolecular weight:299.75Clopenthixol
CAS:Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.Formula:C22H25ClN2OSColor and Shape:SolidMolecular weight:400.96SB-221284
CAS:5-HT2C/2B receptor antagonistFormula:C16H14F3N3OSPurity:98%Color and Shape:SolidMolecular weight:353.36SB-226552
CAS:SB-226552 is an aryloxypropanolamine selective beta3AR agonist.Formula:C25H36NO5PColor and Shape:SolidMolecular weight:461.53A68930
CAS:A 68930 is a dopamine D-1 receptor antagonist. A 68930 inhibits NLRP3 inflammasome activity.Formula:C16H17NO3Color and Shape:SolidMolecular weight:271.31LY 203647
CAS:LY 203647 is a antagonist of leukotriene D4 and E4 receptor.Formula:C21H30N8O3Purity:98%Color and Shape:SolidMolecular weight:442.51AB-MECA
CAS:AB-MECA is a high affinity A3 adenosine receptor agonist. It has high affinity for recombinant A1 and A3 receptors.Formula:C18H21N7O4Purity:98%Color and Shape:SolidMolecular weight:399.4A1/A3 AR antagonist 2
CAS:The compound is an a1/a3 adenosine receptor antagonist, which helps to treat (neurological) inflammatory diseases.Formula:C22H16N2O3SColor and Shape:SolidMolecular weight:388.44Detomidine
CAS:Detomidine is a nonnarcotic, synthetic α2-adrenergic agonist. Detomidine produces dose-dependent sedative and analgesic effects.Formula:C12H14N2Purity:98%Color and Shape:White Crystalline PowderMolecular weight:186.25Indatraline hydrochloride
CAS:Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET)Formula:C16H16Cl3NPurity:98%Color and Shape:SolidMolecular weight:328.66Antiplatelet agent 2
CAS:Antiplatelet agent 2 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies.Formula:C21H24F2N6O4SColor and Shape:SolidMolecular weight:494.51JHW 007 hydrochloride
CAS:JHW 007 hydrochloride is a Dopamine uptake inhibitor.Formula:C24H30ClF2NOPurity:98%Color and Shape:SolidMolecular weight:421.95(S)-Carvedilol
CAS:(S)-Carvedilol is a non-selective β/α-1 blocker.It exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).Formula:C24H26N2O4Purity:98%Color and Shape:Less Crystalline Solid Colourless Crystalline SolidMolecular weight:406.47GT 2016
CAS:GT 2016 is a H3 receptor antagonist.Formula:C19H31N3OPurity:98%Color and Shape:SolidMolecular weight:317.47CAY10788
CAS:CAY10788 is an antagonist of CysLT1 receptor.Formula:C18H15NO3Color and Shape:SolidMolecular weight:293.32ONO-AE-248
CAS:ONO-AE-248 is a selective agonist of EP3 receptor.Formula:C22H36O5Purity:98%Color and Shape:SolidMolecular weight:380.52AVN-101 free base
CAS:AVN-101: potent 5-HT7 antagonist, also targets 5-HT6, 5-HT2A, 5-HT2C. Aims to treat CNS disorders.Formula:C21H24N2Color and Shape:SolidMolecular weight:304.43PD168,077
CAS:PD168,077 is an agonist of dopamine D4 receptor. It has a facilitatory effect on memory consolidation.Formula:C20H22N4OPurity:98%Color and Shape:SolidMolecular weight:334.412-Acetylbenzoic acid
CAS:2-Acetylbenzoic acid outperforms 2-propionyloxybenzoic in hindering platelet function and PG synthesis; both similar in blocking PGI2 creation.Formula:C9H8O3Purity:99.62%Color and Shape:Off-White SolidMolecular weight:164.16WAY 629
CAS:WAY 629 is a selective SR-2C agonist that also act as potent 5-HT2C receptor agonists.Formula:C15H18N2Color and Shape:SolidMolecular weight:226.32Pargolol
CAS:Pargolol is a beta adrenergic receptor antagonist.Formula:C16H23NO3Color and Shape:SolidMolecular weight:277.36BN-81,674
CAS:BN-81,674 is a bioactive chemical.Formula:C30H38N4Color and Shape:SolidMolecular weight:454.65Ridazolol
CAS:Ridazolol is a vasodilating and cardioselective beta adrenergic blocker.Formula:C15H18Cl2N4O3Purity:99.05%Color and Shape:SolidMolecular weight:373.23(1R,1'S,3'R/1R,1'R,3'S)-L-054,264
CAS:somatostatin sst2 receptor agonistFormula:C33H41N5O2Purity:98%Color and Shape:SolidMolecular weight:539.71CP 66713
CAS:CP-66713 is an adenosine A2 receptor antagonist.Formula:C15H10ClN5Color and Shape:SolidMolecular weight:295.73UK-9040
CAS:UK-9040 inhibits gastric secretory.Formula:C23H31NSPurity:98%Color and Shape:SolidMolecular weight:353.56S 32212 hydrochloride
CAS:S 32212 hydrochloride is a high-affinity inverse agonist at the 5-HT2C receptor and an antagonist at the α2-adrenergic receptor, which is antidepressant .Formula:C25H29ClN4O2Purity:97.11% - 99.57%Color and Shape:SolidMolecular weight:452.98BMS-192364
CAS:BMS-192364 is a bio-active chemical.Formula:C15H9ClF3N3O2Color and Shape:SolidMolecular weight:355.70Fenmetozole HCl
CAS:Fenmetozole HCl is an antagonist of the actions of ethanol. It attenuates the ethanol-induced reduction in cerebellar cyclic guanosine monophosphate content.Formula:C10H11Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:281.57Protokylol hydrochloride
CAS:Protokylol hydrochloride is a β-adrenergic agonist and bronchodilator, marketed as Asmetil, Caytine, Palison, Ventaire.Formula:C18H22ClNO5Color and Shape:SolidMolecular weight:367.83Landiolol
CAS:Landiolol is used as a highly cardioselective ultra short-acting beta-blocker.Formula:C25H39N3O8Purity:98%Color and Shape:White Crystalline PowderMolecular weight:509.59MK-4256
CAS:MK-4256 is an effective and selective SSTR3 antagonist (IC50s: 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively).Formula:C27H23FN8OColor and Shape:SolidMolecular weight:494.52Y2 Antagonist 36
CAS:Y2 Antagonist 36 is a highly potent, soluble and selective antagonist of NPY Y2.Formula:C27H29ClN4O3Color and Shape:SolidMolecular weight:493Talipexole
CAS:Talipexole (B-HT920) is an agonist of dopamine, and is an antiparkinsonian agent.Formula:C10H15N3SPurity:98%Color and Shape:SolidMolecular weight:209.31SMM-189
CAS:SMM-189 is a potent and selective CB2 inverse agonist.Formula:C19H12Cl2O3Color and Shape:SolidMolecular weight:359.2CYM-5478
CAS:CYM-5478 is a highly selective S1P2 agonist with an EC50 value of 119 nM and can reduce the toxicity of cisplatin to neurogenic cell lines.Formula:C21H19F3N2O2Purity:98%Color and Shape:SolidMolecular weight:388.38PD 120697
CAS:PD 120697 is a dopamine antagonist with central dopamine agonist properties.Formula:C11H15N3SPurity:98%Color and Shape:SolidMolecular weight:221.32GSK-269984A
CAS:GSK-269984A is an antagonist of Prostaglandin E2 Receptor 1 (EP1) (pIC50: 7.9).Formula:C20H14Cl2FNNaO3Purity:98%Color and Shape:SolidMolecular weight:429.22LG 82-4-01
CAS:LG 82-4-01 is an inhibitor of thromboxane (TX) synthetase.Formula:C10H10Cl2N2O3SPurity:98%Color and Shape:SolidMolecular weight:309.17GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37
