GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,023 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5988 products of "GPCR/G-Protein"
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RS 39604
CAS:potent and selective 5-HT4 antagonistFormula:C26H37Cl2N3O6SPurity:98%Color and Shape:SolidMolecular weight:590.564-Chloro Trazodone hydrochloride
CAS:4-Chloro Trazodone HCl is a Trazodone isomer, an antidepressant for anxiety disorders.Formula:C19H23Cl2N5OColor and Shape:SolidMolecular weight:408.32Ronactolol
CAS:Ronactolol is an aminopropanol derivative with beta-adrenoreceptor blocking activity.Formula:C20H26N2O4Color and Shape:SolidMolecular weight:358.43Noberastine maleate
CAS:Noberastine maleate, a fast-acting furan-derived H1 antagonist, peaks at 4 hours with minimal CNS effects and maximal efficacy at 30 mg/day.Formula:C25H29N5O9Color and Shape:SolidMolecular weight:543.53PSB 11 hydrochloride
CAS:PSB 11 hydrochloride is a human adenosine A3 receptor antagonist.Formula:C16H18ClN5OPurity:98%Color and Shape:SolidMolecular weight:331.8SCH-202676 HBr
CAS:SCH-202676 HBr is an allosteric agonist. It also an GPCR antagonist.Formula:C15H13N3SPurity:98%Color and Shape:SolidMolecular weight:267.35KW-8232 free base
CAS:KW-8232 free base can reduces the biosynthesis of PGE2, is an anti-osteoporotic agent.Formula:C36H37ClN4O3Purity:98%Color and Shape:SolidMolecular weight:609.16GBR-13069 dimethanesulfonate
CAS:GBR-13069 dimethanesulfonate is a dopamine reuptake inhibitor.Formula:C30H38F2N2O7S2Color and Shape:SolidMolecular weight:640.76Anitrazafen
CAS:Anitrazafen is a locally effective anti-inflammatory agent that has been shown to have COX-2 inhibitor activity.Formula:C18H17N3O2Purity:98%Color and Shape:SolidMolecular weight:307.35Tiamenidine hydrochloride
CAS:Tiamenidine hydrochloride is a centrally-acting alpha1 adrenergic receptor antagonist.Formula:C8H11Cl2N3SColor and Shape:SolidMolecular weight:252.16AZ8838
CAS:AZ8838 is an effective, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pK i of 6.4 for hPAR2 [1].Formula:C13H15FN2OColor and Shape:SolidMolecular weight:234.27BMS-193884
CAS:BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.Formula:C20H17N3O4SColor and Shape:SolidMolecular weight:395.43Clopenthixol
CAS:Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.Formula:C22H25ClN2OSColor and Shape:SolidMolecular weight:400.96Substance P Receptor Antagonist 1
CAS:Substance P Receptor Antagonist 1 may aid in treating GI, inflammatory, respiratory, and CNS disorders.Formula:C24H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:434.495-HT7 receptor ligand 1
CAS:Compound 5c: 5-HT7 receptor ligand, K i = 8 nM, not hepatotoxic, moderate CYP3A4/CYP2D6 interaction.Formula:C21H23N7Color and Shape:SolidMolecular weight:373.45Ulimorelin
CAS:Ulimorelin, ghrelin receptor agonist (EC50: 29 nM, Ki: 16 nM), is a prokinetic and vasorelaxant via α1-adrenoceptor antagonism.Formula:C30H39FN4O4Purity:98%Color and Shape:SolidMolecular weight:538.65SC 53116 Hydrochloride
CAS:SC 53116 Hydrochloride is selective agonist of the newly identified serotonin 5-HT4 receptor subtype.Formula:C16H23Cl2N3O2Color and Shape:SolidMolecular weight:360.28Daledalin
CAS:Daledalin, an unmarketed 1970s antidepressant, is a selective norepinephrine reuptake inhibitor without serotonergic or dopaminergic effects.Formula:C19H24N2Color and Shape:SolidMolecular weight:280.41Fenspiride-d5
CAS:Fenspiride-d5: internal standard for GC/LC-MS quantification, H1 antagonist, NSAID, anti-inflammatory, selective PDE4,5,3 inhibitor.Formula:C15H15D5N2O2Color and Shape:SolidMolecular weight:265.36SGC agonist 2
CAS:SGC agonist 2 is a potent activator for cardiovascular and fibrotic diseases, per patent WO2021219088A1, compound 031.Formula:C23H17F2N7O2Color and Shape:SolidMolecular weight:461.42Tesofensine
CAS:Tesofensine, a serotonin–noradrenaline–dopamine reuptake inhibitor, is used potentially for the treatment of obesity.Formula:C17H23Cl2NOPurity:98%Color and Shape:SolidMolecular weight:328.28ChemR23-IN-4
CAS:ChemR23-IN-4 is a potent inhibitor of orally active ChemR23, capable of acting on human ChemR23 (IC50: 17 nM).Formula:C27H26N6O3Color and Shape:SolidMolecular weight:482.53JNJ 10181457 dihydrochloride
CAS:JNJ 10181457 dihydrochloride is a Histamine H3 receptor antagonist.Formula:C20H28N2OPurity:98%Color and Shape:SolidMolecular weight:312.45Cetrorelix Acetate
CAS:Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.Formula:C70H92ClN17O14·xC2H4O2Purity:97.96%Color and Shape:SolidMolecular weight:1491.11AM-6538
CAS:AM6538: long-acting, high-affinity CB antagonist similar to rimonabant, useful for studying cannabinoid agonists.Formula:C26H25Cl2N5O4Color and Shape:SolidMolecular weight:542.41Alniditan dihydrochloride
CAS:Alniditan dihydrochloride is a potent 5-HT1D agonist and migraine-abortive agent.Formula:C17H28Cl2N4OColor and Shape:SolidMolecular weight:375.34p-MPPF dihydrochloride
CAS:p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H29Cl2FN4O2Purity:99.55%Color and Shape:SolidMolecular weight:507.43Phenoprolamine Hydrochloride
CAS:Phenoprolamine HCl: α1 blocker with anti-hypertensive, brain, and heart protection; inhibits CYP2D/3A, crosses the blood-brain barrier.Formula:C21H30ClNO3Color and Shape:SolidMolecular weight:379.92BX 667
CAS:BX 667, a P2Y12 antagonist, inhibits ADP-induced platelet clumping in humans, dogs, rats with IC50s: 97, 317, 3000 nM.Formula:C29H38N4O9Purity:98%Color and Shape:SolidMolecular weight:586.63Guanadrel Sulfate
CAS:Guanadrel Sulfate, a postganglionic blocker, is stored in neurons via the norepinephrine pump.Formula:C10H21N3O6SColor and Shape:White To Off-White Crystalline PowderMolecular weight:311.35A-940894
CAS:A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.Formula:C17H21N5Color and Shape:SolidMolecular weight:295.38ANEB-001
CAS:ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.Formula:C22H24ClF3N2O2Color and Shape:SolidMolecular weight:440.89GAT229
CAS:GAT229 is a CB1 positive modulator, enhancing CB agonist activity without direct activation; influences binding, signaling, and lowers ocular pressure in mice.Formula:C22H18N2O2Color and Shape:SolidMolecular weight:342.39MRS 1334
CAS:antagonist for the human adenosine A3 receptorFormula:C31H26N2O6Purity:98%Color and Shape:SolidMolecular weight:522.555-HT6/5-HT2A receptor ligand-2
CAS:Compound 42: brain-penetrant, dual 5-HT6/5-HT2A antagonist, Ki of 25 nM/32 nM, pro-cognitive.Formula:C20H18FN3O2Color and Shape:SolidMolecular weight:351.37Pargolol
CAS:Pargolol is a beta adrenergic receptor antagonist.Formula:C16H23NO3Color and Shape:SolidMolecular weight:277.36CP-809101
CAS:CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).Formula:C15H17ClN4OPurity:98%Color and Shape:SolidMolecular weight:304.772-Methyl-5-HT maleate
CAS:2-Methyl-5-HT maleate, a selective 5-HT3 agonist, shows anti-depressive effects.Formula:C15H18N2O5Purity:98%Color and Shape:SolidMolecular weight:306.31Seprilose
CAS:Seprilose, prostaglandin E2 inhibitor, inhibits prostaglandin E2 synthesis.Formula:C16H30O6Color and Shape:SolidMolecular weight:318.41Reversan
CAS:Reversan(CBLC4H10) is a potent, nontoxic, and glioblastoma-associated inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp).Formula:C26H27N5O2Purity:99.05%Color and Shape:SolidMolecular weight:441.53Ref: TM-T12714
1mg44.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg130.00€25mg250.00€50mg401.00€100mg640.00€200mg884.00€SNT-207707
CAS:SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor).Formula:C32H44ClN5OPurity:98%Color and Shape:SolidMolecular weight:550.18hGPR91 antagonist 3
CAS:hGPR91 antagonist 3 is an hGPR91 antagonist. hGPR91 antagonist 3 can be used to study diseases in hypertension and retinal angiogenesis.Formula:C23H18F4N4O2Purity:98.82% - 99.347%Color and Shape:SolidMolecular weight:458.41Ref: TM-T62858
1mg123.00€5mg295.00€1mL*10mM (DMSO)299.00€10mg490.00€25mg792.00€50mg1,071.00€100mg1,468.00€200mg1,972.00€(Rac)-SEP-363856
CAS:(Rac)-SEP-363856 is the racemate of SEP-363856. SEP-363856 is an orally active and CNS active psychotropic agent with a uniqueFormula:C9H13NOSPurity:98%Color and Shape:SolidMolecular weight:183.27L-694,247
CAS:L-694,247 is a 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases.Formula:C20H21N5O3SPurity:98.36%Color and Shape:White SolidMolecular weight:411.48Org-10490
CAS:Org-10490 is an dopamine D1 receptor and dopamine D2 receptor antagonist, and treatment for psychiatric disease.Formula:C17H19NOPurity:98%Color and Shape:SolidMolecular weight:253.346-Chloromelatonin
CAS:6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.Formula:C13H15ClN2O2Purity:97.26% - 99.25%Color and Shape:SolidMolecular weight:266.72Ref: TM-T22530
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€Methyldopa hydrochloride
CAS:L-(-)-α-Methyldopa HCl: alpha-adrenergic agonist, antihypertensive, inhibits DOPA decarboxylase.Formula:C10H14ClNO4Purity:98%Color and Shape:SolidMolecular weight:247.68LASSBio-1359
CAS:LASSBio-1359 is an adenosine receptor agonist. It acts by inducing relaxation of the corpus cavernosum. It also acts as a novel selective phosphodiesterase.Formula:C17H18N2O3Purity:98%Color and Shape:SolidMolecular weight:298.34CM398
CAS:CM398, a sigma-2 receptor selective ligand (Ki=0.43 nM), also binds dopamine and serotonin transporters, shows anti-inflammatory analgesic effects.Formula:C23H29N3O3Color and Shape:SolidMolecular weight:395.49LY 334370 hydrochloride
CAS:5-HT1F receptor agonistFormula:C21H23ClFN3OPurity:98%Color and Shape:SolidMolecular weight:387.88
