GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,028 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(61 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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Afurolol Hydrochloride
CAS:Afurolol Hydrochloride (DL 071-IT) is a non-selective β-adrenergic receptor antagonist. DL 071 IT exhibits intrinsic sympathomimetic activity.Formula:C15H22ClNO4Purity:98.86%Color and Shape:SolidMolecular weight:315.79PNU-96391
CAS:PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.Formula:C15H23NO2SPurity:99.53%Color and Shape:SolidMolecular weight:281.41Ref: TM-T28435
1mg73.00€1mL*10mM (DMSO)138.00€5mg146.00€10mg210.00€25mg319.00€50mg447.00€100mg600.00€200mg800.00€GR 55562 dihydrochloride
CAS:5-HT1B (5-HT1Dβ) silent antagonistFormula:C23H27Cl2N3O2Purity:99.45%Color and Shape:SolidMolecular weight:448.39Salmefamol
CAS:Salmefamol is a beta-adrenergic agonist. It may also be used as a bronchodilator.Formula:C19H25NO4Purity:99.89%Color and Shape:SolidMolecular weight:331.41D2343
CAS:D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor.Formula:C20H27NO3Purity:98%Color and Shape:SolidMolecular weight:329.43Sulfinalol
CAS:Sulfinalol is a compound that acts as an orally active β-adrenoceptor antagonist and directly induces vasodilation [1].Formula:C20H27NO4SColor and Shape:SolidMolecular weight:377.52-Methylthio-ATP tetrasodium
CAS:2-Methylthio-ATP tetrasodium is a non-specific P2 receptor agonist, which can activate P2X2 and P2Y1 receptors and inhibiti ADP-induced platelet aggregation.Formula:C11H14N5Na4O13P3SPurity:98%Color and Shape:SolidMolecular weight:641.2Laropiprant
CAS:Laropiprant (MK-0524) is a potent and selective antagonist of prostaglandin D2 (PGD2) receptor (DP) such as and DP/DP1 receptor(Ki = 0.57 nM) and TP Receptor(KiFormula:C21H19ClFNO4SPurity:98.24% - 99.89%Color and Shape:SolidMolecular weight:435.9Ref: TM-T15712
1mg35.00€5mg82.00€1mL*10mM (DMSO)90.00€10mg107.00€25mg207.00€50mg319.00€100mg457.00€200mg623.00€AS19
CAS:AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM).Formula:C18H25N3Purity:98%Color and Shape:SolidMolecular weight:283.41ReN-1869 hydrochloride
CAS:ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor.Formula:C24H28ClNO2Purity:98%Color and Shape:SolidMolecular weight:397.94Efaroxan hydrochloride
CAS:Efaroxan hydrochloride a selective, oral α2-adrenoceptor antagonist significantly potentiates adrenaline-induced increases in insulin levels.Formula:C13H17ClN2OPurity:98%Color and Shape:SolidMolecular weight:252.742-Arachidonoylglycerol
CAS:In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligandFormula:C23H38O4Purity:95%Color and Shape:LiquidMolecular weight:378.55SK1-I hydrochloride
CAS:SK1-I hydrochloride is a selective and competitive SphK1 inhibitor and sphingosine analog ,anti-leukemic to inhibit tumor cell growth and promote apoptosis.Formula:C17H28ClNO2Purity:99.80%Color and Shape:SolidMolecular weight:313.86Carboprost
CAS:Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic.Formula:C21H36O5Purity:98.18%Color and Shape:White Or Almost White PowderMolecular weight:368.51Ref: TM-T22285
1mg43.00€5mg110.00€1mL*10mM (DMSO)122.00€10mg166.00€25mg290.00€50mg425.00€100mg577.00€200mg778.00€PNU-142633
CAS:PNU-142633: anti-migraine, selective 5-HT1D agonist, Ki=6 nM; >18,000 nM for 5-HT1B.Formula:C24H30N4O3Purity:98%Color and Shape:SolidMolecular weight:422.52hGPR91 antagonist 3
CAS:hGPR91 antagonist 3 is an hGPR91 antagonist. hGPR91 antagonist 3 can be used to study diseases in hypertension and retinal angiogenesis.Formula:C23H18F4N4O2Purity:98.82% - 99.347%Color and Shape:SolidMolecular weight:458.41Ref: TM-T62858
1mg123.00€5mg295.00€1mL*10mM (DMSO)299.00€10mg490.00€25mg792.00€50mg1,071.00€100mg1,468.00€200mg1,972.00€Reversan
CAS:Reversan(CBLC4H10) is a potent, nontoxic, and glioblastoma-associated inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp).Formula:C26H27N5O2Purity:99.05%Color and Shape:SolidMolecular weight:441.53Ref: TM-T12714
1mg44.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg130.00€25mg250.00€50mg401.00€100mg640.00€200mg884.00€2-Methyl-5-HT maleate
CAS:2-Methyl-5-HT maleate, a selective 5-HT3 agonist, shows anti-depressive effects.Formula:C15H18N2O5Purity:98%Color and Shape:SolidMolecular weight:306.31ML179
CAS:ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM.Formula:C21H25F3N4O2Purity:99.77%Color and Shape:SolidMolecular weight:422.44Ref: TM-T8954
1mg34.00€5mg75.00€1mL*10mM (DMSO)92.00€10mg110.00€25mg220.00€50mg321.00€100mg469.00€200mg645.00€Etrasimod arginine
CAS:Etrasimod arginine is used in the Treatment of Autoimmune and Inflammatory Diseases.Formula:C32H40F3N5O5Color and Shape:SolidMolecular weight:631.69BRL 44408 Maleate Salt
CAS:BRL 44408 Maleate is an α2A-adrenoceptor antagonist with antidepressant and analgesic activity.Formula:C17H21N3O4Purity:98.71%Color and Shape:SolidMolecular weight:331.37cis-Epoxysuccinic acid
CAS:cis-Epoxysuccinic acid is a potential agonist of Succinate receptor 1 and inhibitor of Isocitrate lyase 1 for use in biochemical experiments.Formula:C4H4O5Purity:99.81%Color and Shape:SolidMolecular weight:132.07Fallypride
CAS:Fallypride is a potent and selective dopamine D2/D3 receptor antagonist.Formula:C20H29FN2O3Purity:98.97% - >99.99%Color and Shape:SolidMolecular weight:364.45Ref: TM-T70302
1mg340.00€1mL*10mM (DMSO)640.00€5mg797.00€10mg982.00€25mg1,575.00€50mg1,963.00€100mg2,520.00€Bemesetron
CAS:Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.Formula:C15H17Cl2NO2Purity:99.77%Color and Shape:SolidMolecular weight:314.21BMY-25271
CAS:BMY-25271 is an antagonist of histamine H2 receptor.Formula:C12H19N5O2S2Purity:98%Color and Shape:SolidMolecular weight:329.44Alniditan
CAS:Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.Formula:C17H26N4OPurity:98%Color and Shape:SolidMolecular weight:302.415-HT7 agonist 1
CAS:5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).Formula:C19H20ClN3Purity:98.61%Color and Shape:SolidMolecular weight:325.84Ref: TM-T10170
1mg109.00€2mg163.00€5mg241.00€1mL*10mM (DMSO)241.00€10mg355.00€25mg532.00€50mg745.00€100mg1,018.00€TSI-01
CAS:TSI-01,Pro-inflammatory phospholipid mediator. Inhibits LPCAT2 (IC50=0.47 μM). Suppresses PAF biosynthesis in macrophages.Formula:C14H11Cl2NO4Purity:99.87%Color and Shape:SolidMolecular weight:328.15Ref: TM-T24904
1mg83.00€5mg175.00€1mL*10mM (DMSO)193.00€10mg305.00€25mg659.00€50mg1,046.00€100mg1,607.00€200mg2,164.00€Repinotan HCl
CAS:Repinotan HCl (Bay-x-3702) is a 5-HT1A receptor agonist with potent neuroprotective effects for the study of ischemic stroke and traumatic brain injury.Formula:C21H25ClN2O4SPurity:99.57%Color and Shape:SolidMolecular weight:436.95ZK-90055 hydrochloride
CAS:ZK-90055 hydrochloride is a β2 adrenergic receptor agonist used to study asthma.Formula:C16H23ClN2O4Purity:99.26%Color and Shape:SolidMolecular weight:342.82Apadenoson
CAS:Apadenoson: potent A2 agonist, A3 inhibitor (IC 45 nM), anti-inflammatory, for neurological research.Formula:C23H30N6O6Purity:98%Color and Shape:SolidMolecular weight:486.52Lintopride
CAS:Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.Formula:C14H19ClN4O2Purity:98%Color and Shape:SolidMolecular weight:310.78Cinitapride Hydrogen Tartrate
CAS:Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptorsFormula:C25H36N4O10Purity:98%Color and Shape:SolidMolecular weight:552.581EP3 antagonist 3
CAS:EP3 antagonist 3, potent and selective oral, inhibited GR63799- or acetic acid-induced reduction in bladder capacity and PGE2-induced overactive bladder model.Formula:C21H18N2O4Color and Shape:SolidMolecular weight:362.38ONO-8713
CAS:ONO-8713 is a selective prostaglandin E receptor subtype EP1 antagonist that can be used to study diseases of the biblical system and metabolism-relatedFormula:C25H24F3NO6SPurity:99.97%Color and Shape:SolidMolecular weight:523.52CP-226269
CAS:CP-226269 is a potent dopamine D4 receptor agonist that regulates calcium flux and has an EC50 value of 32.0 nM.
Formula:C18H19FN4Purity:99.08%Color and Shape:SolidMolecular weight:310.37L-740093
CAS:L-740093 is a specific antagonist of CCK-B receptor.Formula:C26H31N5O2Purity:98%Color and Shape:SolidMolecular weight:445.56S 16924
CAS:S 16924 is a 5-HT 1A agonist with potential anxiolytic effects and may be useful in the study of neurologic disorders.Formula:C22H24FNO4Purity:99.35% - 99.6%Color and Shape:SolidMolecular weight:385.43ESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formula:C20H23N3OSPurity:97.17%Color and Shape:SolidMolecular weight:353.48Dicarbine
CAS:Double carbene blocks dopamine receptors, aiding schizophrenia and alcoholism research; it maintains defense reflexes despite mid-brain stimulation.Formula:C13H18N2Purity:98%Color and Shape:SolidMolecular weight:202.3Aganepag
CAS:Aganepag: Potent EP2 agonist, EC50 0.19 nM, inactive at EP4, used in wound healing and scar/wrinkle treatment research.Formula:C24H31NO4SPurity:98%Color and Shape:SolidMolecular weight:429.57Atrasentan hydrochloride
CAS:Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).Formula:C29H39ClN2O6Purity:99.75%Color and Shape:SolidMolecular weight:547.08A2AR-agonist-1
CAS:A2AR-agonist-1 targets A2A Receptor/ENT1 for neuroprotection; potent with Ki of 4.39 (A2AR), 3.47 (ENT1).Formula:C20H22N6O4Purity:99.9%Color and Shape:SolidMolecular weight:410.43Ref: TM-T10212
1mg90.00€2mg127.00€5mg178.00€1mL*10mM (DMSO)207.00€10mg269.00€25mg427.00€50mg610.00€100mg820.00€500mg1,603.00€SB-269970
CAS:SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).Formula:C18H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:352.49WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Formula:C24H25NO10SPurity:98%Color and Shape:SolidMolecular weight:519.52VNA-932
CAS:VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay).Formula:C23H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:402.88GBR 13069 dihydrochloride
CAS:GBR 13069 dihydrochloride is a dopamine uptake inhibitor.Formula:C28H32Cl2F2N2OPurity:98%Color and Shape:SolidMolecular weight:521.47(R)-SLV 319
CAS:(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.Formula:C23H20Cl2N4O2SColor and Shape:SolidMolecular weight:487.4DS-3801b
CAS:DS-3801b is a non-macrolide GPR38 agonist with an N-methylaniline structure for the study of functional gastrointestinal disorders.Formula:C28H39N3O3Purity:99.21%Color and Shape:SolidMolecular weight:465.63GSK1059865
CAS:GSK1059865 is a potent antagonist of the orexin 1 receptor.Formula:C20H23BrFN3O2Color and Shape:SolidMolecular weight:436.32
