GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,027 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Bambuterol
CAS:long acting beta-adrenoceptor agonistFormula:C18H29N3O5Purity:98%Color and Shape:Off-White PowderMolecular weight:367.44TMPPAA
CAS:TMPPAA is an allosteric agonist of 5-HT3 receptor.Formula:C15H21NO2Purity:98%Color and Shape:SolidMolecular weight:247.33Oxypertine
CAS:Oxypertine, an indole-derived antipsychotic, treats psychoses like mania, schizophrenia, and severe anxiety, akin to chlorpromazine.Formula:C23H29N3O2Color and Shape:SolidMolecular weight:379.5Adriforant hydrochloride
CAS:Adriforant hydrochloride is an antagonist of histamine H4 receptor.Formula:C13H25Cl3N6Purity:98%Color and Shape:SolidMolecular weight:371.74A2AAR antagonist 1
CAS:Compound 21a, A2AAR antagonist with 20 nM Ki, useful in neurodegenerative disease study.Formula:C12H8BrN3OColor and Shape:SolidMolecular weight:290.12PNU-96415E
CAS:dopamine D4 and serotonergic 5-HT2A receptor antagonistFormula:C21H27Cl2FN2OPurity:98%Color and Shape:SolidMolecular weight:413.36ZD 7114 hydrochloride
CAS:β3-adrenoceptor agonistFormula:C22H31ClN2O6Purity:98%Color and Shape:SolidMolecular weight:454.94Calhex 231 hydrochloride
CAS:Calhex 231 hydrochloride a potent CaSR negative-conversion modulator that blocks the increase in [3H]inositol phosphate, inhibits mir-208a-mediated .Formula:C25H28Cl2N2OPurity:99.36%Color and Shape:SolidMolecular weight:443.41SKF-75670 Hydrobromide
CAS:SKF-75670 hydrobromide is an atypical D1DR (dopamine receptor) agonist. It displays agonist activity in vivo and antagonist activity in vitro.Formula:C17H20BrNO2Color and Shape:SolidMolecular weight:350.25Zicronapine
CAS:Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.Formula:C22H27ClN2Color and Shape:SolidMolecular weight:354.925-HT7 agonist 2
CAS:Potent 5-HT7 agonist with 28.7 nM IC50; promising for CNS disorder research.Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.5Mianserin
CAS:Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family.Formula:C18H20N2Purity:99.85%Color and Shape:SolidMolecular weight:264.36CCR4 antagonist 3-1
CAS:CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.Formula:C14H12N2SPurity:99.87%Color and Shape:SolidMolecular weight:240.32Anitrazafen
CAS:Anitrazafen is a locally effective anti-inflammatory agent that has been shown to have COX-2 inhibitor activity.Formula:C18H17N3O2Purity:98%Color and Shape:SolidMolecular weight:307.35Ancarolol
CAS:Ancarolol is a blocking agent of beta-adrenergic.Formula:C18H24N2O4Purity:98%Color and Shape:SolidMolecular weight:332.39A 55453
CAS:A 55453 is a radiated ionophore used as a reversibl, high-affinity alpha 1-adrenergic receptor probe.Formula:C25H32N6O3Color and Shape:SolidMolecular weight:464.56mPGES-1 Inhibitor-1
CAS:mPGES-1 Inhibitor-1 is an mPGES-1 inhibitor with anti-inflammatory and analgesic activity, which can be used to study acute liver injury.Formula:C16H19ClN4O2Purity:96.84% - 98.75%Color and Shape:SolidMolecular weight:334.8EP4 receptor antagonist 4
CAS:EP4 receptor antagonist 4 is an agonist of EP4 receptor (human pEC 50 = 6.3) [1].Formula:C19H14N2OSColor and Shape:SolidMolecular weight:318.39FRG8701
CAS:FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.Formula:C22H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:418.55Guanethidine
CAS:Guanethidine sulphate, made in 1959, lowers blood pressure by disrupting neurotransmitters in sympathetic nerves.Formula:C10H22N4Color and Shape:SolidMolecular weight:198.31NAEPA
CAS:NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor.Formula:C20H40NO5PPurity:98%Color and Shape:SolidMolecular weight:405.51GSK-269984B
CAS:GSK-269984B is a novel antagonist of EP1 receptor.Formula:C20H14Cl2FNO3Purity:98%Color and Shape:SolidMolecular weight:406.23EP2 receptor antagonist-1
CAS:EP2 receptor antagonist-1: reversible, potent, depends on agonist; anti-inflammatory.Formula:C24H22N4O5Color and Shape:SolidMolecular weight:446.46LY288513
CAS:Selective CCK2 receptor antagonistFormula:C22H18BrN3O2Purity:98%Color and Shape:SolidMolecular weight:436.3Dothiepin HCl
CAS:Dothiepin HCl: TCA, SNRI, with antihistamine, antiadrenergic, anticholinergic, and sodium block properties.Formula:C19H22ClNSColor and Shape:SolidMolecular weight:331.9CP-195543
CAS:CP-195543 is an effective leukotriene B4 antagonist for the treatment of inflammatory diseases.Formula:C24H19F3O4Color and Shape:SolidMolecular weight:428.4Zenidolol
CAS:Zenidolol (ICI-118551) is a β2 adrenoceptor blocker with K i values: β2 (0.7 nM), β1 (49.5 nM), β3 (611 nM); used in eye disease research.Formula:C17H27NO2Color and Shape:SolidMolecular weight:277.4WB403
CAS:WB403 activates TGR5, lowers fasting/postprandial glucose and HbA1c, enhances glucose tolerance, and normalizes pancreatic α/β-cells in diabetic mice.Formula:C19H19BrN2OSPurity:98%Color and Shape:SolidMolecular weight:403.34UK 1745
CAS:UK 1745 is a novel drug of cardiotonic.Formula:C16H23ClN2O2Color and Shape:SolidMolecular weight:310.82QCC-374
CAS:QCC-374 is a prostanoid agonist. It potentially for the treatment of pulmonary arterial hypertension.Formula:C28H33N3O2Purity:98%Color and Shape:SolidMolecular weight:443.58GSK-269984A
CAS:GSK-269984A is an antagonist of Prostaglandin E2 Receptor 1 (EP1) (pIC50: 7.9).Formula:C20H14Cl2FNNaO3Purity:98%Color and Shape:SolidMolecular weight:429.22SB 207710
CAS:SB 207710 is a selective and high affinity antagonist of 5-HT4 receptor.Formula:C19H27IN2O4Color and Shape:SolidMolecular weight:474.33Fluprostenol methyl ester
CAS:Fluprostenol, a vet-approved luteolytic, has an isopropyl ester, travoprost, used as an eye pressure reducer. CAY10532 is its methyl ester form.Formula:C24H31F3O6Color and Shape:SolidMolecular weight:472.49(Rac)-HAMI 3379
CAS:HAMI 3379: potent CysLT2 receptor blocker; protects against acute/subacute brain injury; reduces microglia inflammation.Formula:C34H45NO8Purity:98%Color and Shape:SolidMolecular weight:595.72PD-135666
CAS:PD-135666 is an antagonist of CCK receptor.Formula:C33H39N3O5Purity:98%Color and Shape:SolidMolecular weight:557.68BRL 37344 sodium
CAS:BRL 37344 sodium is a specific agonist of the β3-adrenergic receptor. The treatment of BRL 37344 sodium significantly lowers the bodyweight of obese mice.Formula:C19H22ClNNaO4Purity:98%Color and Shape:SolidMolecular weight:386.83A-943931
CAS:A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.Formula:C17H21N5Purity:99.79%Color and Shape:SolidMolecular weight:295.38Methyldopate hydrochloride
CAS:Methyldopate HCl is an agent of antihypertensive.Formula:C12H18ClNO4Color and Shape:SolidMolecular weight:275.73MK-8133
CAS:MK-8133 is an antagonist of orexin-2 selective receptor with favorable development properties.Formula:C23H21N5O2Color and Shape:SolidMolecular weight:399.45Isamoltane
CAS:Isamoltane is a serotonin 5-HT1 Receptor AntagonistFormula:C16H23ClN2O2Color and Shape:SolidMolecular weight:310.822-Methyl-5-HT maleate
CAS:2-Methyl-5-HT maleate, a selective 5-HT3 agonist, shows anti-depressive effects.Formula:C15H18N2O5Purity:98%Color and Shape:SolidMolecular weight:306.31VUF14862
CAS:VUF14862 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Formula:C26H32N4O2Color and Shape:SolidMolecular weight:432.56Izuforant
CAS:Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).Formula:C12H12BrN7Color and Shape:SolidMolecular weight:334.17Autotaxin-IN-6
CAS:Autotaxin-IN-6 is a strong ATX inhibitor with a 30 nM IC50, potentially aiding anticancer research by hindering cell migration.Formula:C35H54BNO6Color and Shape:SolidMolecular weight:595.62PQ-69
CAS:PQ-69 is a selective adenosine A1 receptor antagonist with inverse agonist activity.Formula:C20H19FN4OColor and Shape:SolidMolecular weight:350.39Way 100135
CAS:WAY-100135: research drug, phenylpiperazine, potent 5-HT1A antagonist, partial 5-HT1D agonist, minor 5-HT1B activity.Formula:C24H33N3O2Color and Shape:SolidMolecular weight:395.54Naronapride
CAS:Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.Formula:C27H41ClN4O5Color and Shape:SolidMolecular weight:537.09LY 219057
CAS:LY 219057 is a potent, competitive, and specific antagonist of CCK receptor on the exocrine pancreas.Formula:C23H17ClF3N3OSColor and Shape:SolidMolecular weight:475.91LY314228
CAS:LY314228 is an antagonist of 5-HT2A receptor.Formula:C20H24N4O3Color and Shape:SolidMolecular weight:368.43VPC 23019
CAS:VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively).Formula:C17H29N2O5PPurity:98%Color and Shape:SolidMolecular weight:372.4
