GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,023 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5988 products of "GPCR/G-Protein"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BI-6901
CAS:BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.Formula:C23H27N5O3SPurity:99.83% - 99.94%Color and Shape:SolidMolecular weight:453.56S(-)-8-Hydroxy-DPAT hydrobromide
CAS:S(-)-8-Hydroxy-DPAT hydrobromide is an agonist of 5-HT1A serotonin receptor.Formula:C16H26BrNOPurity:98%Color and Shape:SolidMolecular weight:328.29PD 118440
CAS:PD 118440 is a Dopamine antagonist. PD 118440 is an orally active dopamine (DA) agonists with pronounced central nervous system effects.Formula:C11H17N3SPurity:98%Color and Shape:SolidMolecular weight:223.34NVP-QAV-680
CAS:NVP-QAV-680: Powerful, selective CRTh2 antagonist with nM potency inhibiting eosinophil/Th2 activation.Formula:C18H18N2O4SPurity:98%Color and Shape:SolidMolecular weight:358.41GW-876167
CAS:GW-876167, a 5-HT2C agonist, is used potentially for the treatment of obesity and glaucoma.Formula:C16H21N5O2Purity:98%Color and Shape:SolidMolecular weight:315.37EP1-antagonist-1
CAS:EP1-antagonist-1 (EP1 antagonist 1) is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).Formula:C19H15BrCl2N2O3Purity:97.06%Color and Shape:SolidMolecular weight:470.14SB 272183
CAS:SB 272183 is a highly potent dual 5-HT1A and 5-HT1B antagonists as potential antidepressant drug.Formula:C29H28ClN5OPurity:98%Color and Shape:SolidMolecular weight:498.02Sch 24518
CAS:Sc h24518 is an antagonist of D1 receptor.Formula:C16H17BrClNOPurity:98%Color and Shape:SolidMolecular weight:354.67EMD 56551
CAS:EMD 56551 is a selective small molecule 5-HT1A receptor agonist with anxiolytic activity for the study of anxiety disorders.Formula:C24H31N3O2Purity:95.64% - 99.39%Color and Shape:SolidMolecular weight:393.522Tilisolol HCl
CAS:Tilisolol, a nonselective beta-blocker, dilates dog coronary arteries via ATP-sensitive K(+) channels.Formula:C17H25ClN2O3Purity:98%Color and Shape:SolidMolecular weight:340.85mPGES-1 Inhibitor-1
CAS:mPGES-1 Inhibitor-1 is an mPGES-1 inhibitor with anti-inflammatory and analgesic activity, which can be used to study acute liver injury.Formula:C16H19ClN4O2Purity:96.84% - 98.75%Color and Shape:SolidMolecular weight:334.8MK-0249
CAS:MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).
Formula:C23H24F3N3O2Purity:99.90%Color and Shape:SolidMolecular weight:431.45H3 receptor-MO-1
CAS:H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.Formula:C20H27N3O2Purity:99.11%Color and Shape:SolidMolecular weight:341.45Rocastine
CAS:Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.Formula:C13H19N3OSPurity:98.26%Color and Shape:SolidMolecular weight:265.37QF0301B
CAS:QF0301B is a potent α1-adrenergic receptor antagonist with inhibitory effects on α2-adrenergic receptors, 5-HT2A and histamine H1 receptors.Formula:C23H28N2O2Purity:>99.99%Color and Shape:SolidMolecular weight:364.48Tulopafant
CAS:Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival.Formula:C25H19N3O2SPurity:99.38%Color and Shape:SolidMolecular weight:425.5CL-216303 HCl
CAS:CL-216303 HCl, a dopamine transporter inhibitor and a 5-HT inhibitor, is used potentially for the treatment of depression.Formula:C11H12Cl3NPurity:98%Color and Shape:SolidMolecular weight:264.58Oxiperomide
CAS:Oxiperomide is a dopamine D2 and muscarinic M1 receptor ligand. It also has putative antipsychotic and pro-cognitive potential.Formula:C20H23N3O2Purity:98%Color and Shape:SolidMolecular weight:337.42(S)-(-)-Propranolol hydrochloride
CAS:(S)-(-)-Propranolol hydrochloride 是一种有效的肾上腺素能受体 (β-adrenergic receptor) 拮抗剂，具有抗高血压活性和潜在的抗癌活性，对β1，β2，和β3受体有抑制作用。(S)-(-)-Propranolol hydrochloride 可改善严重烧伤患者的预后，可用于研究酒精症。Formula:C16H22ClNO2Purity:99.02% - 99.91%Color and Shape:SolidMolecular weight:295.8Befetupitant
CAS:Befupupitant(Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization.Formula:C29H29F6N3O2Purity:98.72%Color and Shape:SolidMolecular weight:565.55Alosetron ((Z)-2-butenedioate)
CAS:Alosetron (GR 68755) (Z)-2-butenedioate is a Serotonin 5HT3-receptor antagonist that is used in the treatment of irritable bowel syndrome.Formula:C21H22N4O5Purity:98%Color and Shape:SolidMolecular weight:410.42Aminaftone
CAS:Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.Formula:C18H15NO4Purity:96.31% - 99.39%Color and Shape:SolidMolecular weight:309.32Glucagon receptor antagonists-2
CAS:Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.Formula:C22H30FNO2Purity:98%Color and Shape:SolidMolecular weight:359.48Isoproterenol-d7 HCl
CAS:Isoproterenol-d7: internal standard for GC/LC-MS. β1-/β2-AR agonist, not for β3. Lowers blood pressure, tackles bradydysrhythmias, asthma.Formula:C11H18ClNO3Color and Shape:SolidMolecular weight:254.76LY 163443
CAS:LY 163443 is an dual receptor antagonist of LTD4 and LTE4.Formula:C20H22N4O3Color and Shape:SolidMolecular weight:366.41CCK-A receptor inhibitor 1
CAS:CCK-A receptor inhibitor 1 is a potent inhibitor of the cholecystokinin A (CCK-A) receptor (IC50: 340 nM).CCK-A receptor inhibitor 1 can be used for the studyFormula:C25H35NO6SPurity:99.47%Color and Shape:SolidMolecular weight:477.61Pamatolol
CAS:Pamatolol is a selective and potent beta-adrenoceptor antagonist that has not shown sympathomimetic activity in ex vivo experiments.Formula:C16H26N2O4Purity:>99.99%Color and Shape:SolidMolecular weight:310.39Cicloprolol hydrochloride
CAS:Cicloprolol hydrochloride is a new potent and selective beta 1-adrenoceptor antagonist with partial agonist activity for the study of coronary heart disease.Formula:C18H30ClNO4Purity:97.26%Color and Shape:SolidMolecular weight:359.89Bamirastine
CAS:Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect onFormula:C31H37N5O3Purity:96.68%Color and Shape:SolidMolecular weight:527.66(4E)-SUN9221
CAS:(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity inFormula:C25H31FN4O3Purity:97.79%Color and Shape:SolidMolecular weight:454.54L-733060 hydrochloride
CAS:Potent NK1 antagonistFormula:C20H20ClF6NOPurity:98%Color and Shape:SolidMolecular weight:439.82L-771688
CAS:L-771688 (SNAP 6383) is a novel potent and selective α1A-adrenoceptor antagonist with a Ki value of 0.43±0.02 nM.L-771688 KE is used for the treatment of benignFormula:C28H33F2N5O5Purity:94.15%Color and Shape:SolidMolecular weight:557.59JNJ-10191584
CAS:JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammationFormula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.74ONO4057
CAS:ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM.Formula:C27H34O7Purity:>99.99%Color and Shape:SolidMolecular weight:470.55PAF-AN-1
CAS:PAF-AN-1 is a novel potent platelet-activating factor receptor (PAF) antagonist involved in the study of anaphylactic death.Formula:C28H28N2O3Purity:98.06%Color and Shape:SolidMolecular weight:440.53L-803087
CAS:L-803087: potent sst4 receptor agonist, 0.7 nM Ki, 280x selectivity, boosts AMPA responses & seizures in mice.Formula:C25H29F2N5O3Purity:99.37%Color and Shape:SolidMolecular weight:485.53Ref: TM-T11800
1mg50.00€5mg112.00€1mL*10mM (DMSO)126.00€10mg175.00€25mg366.00€50mg585.00€100mg928.00€200mg1,234.00€CP-66948
CAS:CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa.Formula:C13H20N6SPurity:99.14%Color and Shape:SolidMolecular weight:292.4Indanidine
CAS:Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in theFormula:C11H13N5Purity:>99.99%Color and Shape:SolidMolecular weight:215.25RS-601
CAS:RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in aFormula:C22H23F6NO4SPurity:99.31%Color and Shape:SolidMolecular weight:511.48Alimemazine
CAS:Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.Formula:C18H22N2SPurity:98%Color and Shape:Crystals SolidMolecular weight:298.45Loratadine N-oxide
CAS:Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.Formula:C22H23ClN2O3Color and Shape:SolidMolecular weight:398.88TD-5471 hydrochloride
CAS:TD-5471 hydrochloride is a selective and potent long-acting human β2-adrenergic receptor agonist for the treatment of chronic obstructive pulmonary disease (Formula:C32H32ClN3O4Purity:99.57%Color and Shape:SolidMolecular weight:558.07Masupirdine mesylate
CAS:Masupirdine mesylate (SUVN-502 mesylate) is a 5-HT6 receptor antagonist.Masupirdine mesylate is used to study neurological disorders such as Alzheimer's diseaseFormula:C23H32BrN3O9S3Purity:99.57%Color and Shape:SolidMolecular weight:670.61Odapipam
CAS:Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).Formula:C19H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:329.82NGB 2904 hydrochloride
CAS:dopamine D3 receptor antagonistFormula:C28H30Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:530.92Org-13011 fumarate
CAS:Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders.Formula:C22H29F3N4O5Purity:98.92%Color and Shape:SolidMolecular weight:486.48MRGPRX1 agonist 2
CAS:MRGPRX1 agonist 2 is a potent modulator with 0.48 μM EC50, potential for neuropathic pain research.Formula:C15H14N2OSColor and Shape:SolidMolecular weight:270.35PF-03654764
CAS:PF-03654764, an oral H3 receptor blocker, Ki: human 1.2 nM, rat 7.9 nM, used with Fexofenadine for allergic rhinitis.Formula:C20H28F2N2OPurity:>99.99%Color and Shape:SolidMolecular weight:350.45Napitane
CAS:napitane (A 75200) is a novel catecholamine uptake inhibitor with inhibitory effects on α-adrenergic receptors and potential antidepressant activity for the
Formula:C22H25NO2Purity:99.77% - 99.89%Color and Shape:SolidMolecular weight:335.44Etersalate
CAS:Etersalate inhibits platelet function. It also reduces thromboxane A2 (TXA2) levels.Formula:C19H19NO6Purity:98%Color and Shape:SolidMolecular weight:357.36
