GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,017 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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Fenspiride-d5
CAS:Fenspiride-d5: internal standard for GC/LC-MS quantification, H1 antagonist, NSAID, anti-inflammatory, selective PDE4,5,3 inhibitor.Formula:C15H15D5N2O2Color and Shape:SolidMolecular weight:265.36SGC agonist 2
CAS:SGC agonist 2 is a potent activator for cardiovascular and fibrotic diseases, per patent WO2021219088A1, compound 031.Formula:C23H17F2N7O2Color and Shape:SolidMolecular weight:461.42ChemR23-IN-4
CAS:ChemR23-IN-4 is a potent inhibitor of orally active ChemR23, capable of acting on human ChemR23 (IC50: 17 nM).Formula:C27H26N6O3Color and Shape:SolidMolecular weight:482.53PRX933 hydrochloride
CAS:PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.Formula:C16H22ClN5O2Purity:99.51% - 99.89%Color and Shape:SolidMolecular weight:351.84Ref: TM-T12565
1mg338.00€5mg538.00€10mg858.00€25mg1,269.00€50mg1,720.00€100mg2,305.00€1mL*10mM (DMSO)618.00€Naxifylline
CAS:Naxifylline is an A1 adenosine receptor blocker that increases urine and protects kidneys during edema treatment in heart failure.Formula:C18H24N4O3Color and Shape:SolidMolecular weight:344.41ADRA1D receptor antagonist 1 HCl
CAS:ADRA1D receptor antagonist 1 HCl is a selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) with potential antiproliferative activity.Formula:C15H14Cl2N4OPurity:98.13%Color and Shape:SolidMolecular weight:337.2CAY10788
CAS:CAY10788 is an antagonist of CysLT1 receptor.Formula:C18H15NO3Color and Shape:SolidMolecular weight:293.32ONO-AE-248
CAS:ONO-AE-248 is a selective agonist of EP3 receptor.Formula:C22H36O5Purity:98%Color and Shape:SolidMolecular weight:380.52AVN-101 free base
CAS:AVN-101: potent 5-HT7 antagonist, also targets 5-HT6, 5-HT2A, 5-HT2C. Aims to treat CNS disorders.Formula:C21H24N2Color and Shape:SolidMolecular weight:304.43Guanadrel Sulfate
CAS:Guanadrel Sulfate, a postganglionic blocker, is stored in neurons via the norepinephrine pump.Formula:C10H21N3O6SColor and Shape:White To Off-White Crystalline PowderMolecular weight:311.35Colterol (free base)
CAS:Colterol: short-acting β2 agonist; Bitolterol prodrug treats asthma, COPD bronchospasm.Formula:C12H19NO3Color and Shape:SolidMolecular weight:225.28CP 66713
CAS:CP-66713 is an adenosine A2 receptor antagonist.Formula:C15H10ClN5Color and Shape:SolidMolecular weight:295.73GSK-269984B
CAS:GSK-269984B is a novel antagonist of EP1 receptor.Formula:C20H14Cl2FNO3Purity:98%Color and Shape:SolidMolecular weight:406.23M-25
CAS:M-25 is a Smoothened antagonist and inhibitor of the Hedgehog pathway.Formula:C23H29N3O2Color and Shape:SolidMolecular weight:379.5Y2 Antagonist 36
CAS:Y2 Antagonist 36 is a highly potent, soluble and selective antagonist of NPY Y2.Formula:C27H29ClN4O3Color and Shape:SolidMolecular weight:493CAY10412
CAS:Anandamide (AEA) is an endocannabinoid with neural reuptake. CAY10412, an AEA analog, inhibits this reuptake without binding to CB receptors.Formula:C25H36O2SColor and Shape:SolidMolecular weight:400.62Licogliflozin
CAS:Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).Formula:C23H28O7Purity:98%Color and Shape:SolidMolecular weight:416.46L-692429
CAS:L-692429 (MK-0751) is a GHS agonist with high affinity for G protein-coupled receptors and can be used to study acromegaly and obesity.Formula:C29H31N7O2Purity:98.64% - 99.90%Color and Shape:SolidMolecular weight:509.614Ref: TM-T11798
1mg147.00€5mg356.00€10mg530.00€25mg848.00€50mg1,153.00€100mg1,549.00€1mL*10mM (DMSO)400.00€T-0509
CAS:T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-
Formula:C18H23NO5Purity:97.52% - 98.43%Color and Shape:SolidMolecular weight:333.38Thiothixene hydrochloride
CAS:Thiothixene hydrochloride is an antipsychotic agent that can be used in the study of schizophrenia and bipolar mania.Formula:C23H30ClN3O2S2Color and Shape:SolidMolecular weight:480.08PGN-9856
CAS:PGN-9856 is an EP2 receptor ligand and EP2 receptor agonist with anti-inflammatory and intraocular pressure-lowering properties, useful for glaucoma research.Formula:C21H15F2NO4Purity:99.27%Color and Shape:SolidMolecular weight:383.35MK-2894
CAS:MK-2894 is a highly potent and selective antagonist of second generation EP4 .Formula:C25H22F3NO3SPurity:99.22%Color and Shape:SolidMolecular weight:473.51Ref: TM-T12061
1mg57.00€5mg120.00€10mg205.00€25mg497.00€50mg879.00€100mg1,161.00€500mg2,367.00€1mL*10mM (DMSO)128.00€LY288513
CAS:Selective CCK2 receptor antagonistFormula:C22H18BrN3O2Purity:98%Color and Shape:SolidMolecular weight:436.3Photoregulin1
CAS:Photoregulin1 modulates Nr2e3, slows photoreceptor degeneration in RhoP23H, Pde6brd1 mouse RP models.Formula:C21H23N3O2SColor and Shape:SolidMolecular weight:381.49L-694,247
CAS:L-694,247 is a 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases.Formula:C20H21N5O3SPurity:98.36%Color and Shape:White SolidMolecular weight:411.48NR2F1 agonist 1
CAS:NR2F1 agonist 1 activates cancer cell dormancy, suppresses growth in HNSCC, and inhibits tumor growth in mice.Formula:C28H30N4OSColor and Shape:SolidMolecular weight:470.63(S)-Azelastine
CAS:(S)-Azelastine is an antihistamine reducing receptors H1R, M1R, M3R, and inhibiting HNEpC cell growth.Formula:C22H24ClN3OColor and Shape:SolidMolecular weight:381.9SC 51089
CAS:SC 51089 is a somatic PGE2 antagonist with anti-injurious activity and may rescue memory loss.Formula:C22H20Cl2N4O3Purity:98%Color and Shape:SolidMolecular weight:459.33Efpeglenatide
CAS:Efpeglenatide is a long-acting GLP-1 receptor agonist that improves insulin sensitivity, lowers blood glucose, delays weight gain, and supports metabolic disease research.Purity:100% - 100%Color and Shape:SolidVPC12249
CAS:VPC12249, a lysophosphatidic acid receptor type 1 (LPA1) antagonist, plays a functional role in osteoclast differentiation and bone resorption activity.Formula:C34H52NO6PColor and Shape:SolidMolecular weight:601.75CB1R Allosteric modulator 3
CAS:CB1R Allosteric modulator 3 is a CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP, and can be used for the study of obesity and nicotine addiction.Formula:C22H17ClN2O2Purity:98.18%Color and Shape:SolidMolecular weight:376.84L 651142
CAS:L 651142 is a weak inhibitor of the platelet-activating factor receptor. It is also binding to polymorphonuclear leukocytes.Formula:C21H23NO4SColor and Shape:SolidMolecular weight:385.48Octoclothepin maleate salt
CAS:Octoclothepin maleate salt is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist.Formula:C23H25ClN2O4SColor and Shape:SolidMolecular weight:460.97EA-230
CAS:Ea-230 is an immunomodulator that may be used in the treatment of renal failure.Formula:C15H27N5O6Color and Shape:SolidMolecular weight:373.4Lesopitron dihydrochloride
CAS:Lesopitron dihydrochloride with IC50 of 125 nM in rat hippocampal membranes, is a full and selective 5-HT1A receptor agonist.Formula:C15H23Cl3N6Purity:98%Color and Shape:SolidMolecular weight:393.74mPGES-1 Inhibitor-1
CAS:mPGES-1 Inhibitor-1 is an mPGES-1 inhibitor with anti-inflammatory and analgesic activity, which can be used to study acute liver injury.Formula:C16H19ClN4O2Purity:96.84% - 98.75%Color and Shape:SolidMolecular weight:334.8Org-13011 fumarate
CAS:Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders.Formula:C22H29F3N4O5Purity:98.92%Color and Shape:SolidMolecular weight:486.48CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Formula:C22H22ClN7O2Purity:99.43% - 99.44%Color and Shape:SolidMolecular weight:451.91Azelastine
CAS:Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.Formula:C22H24ClN3OPurity:99.35% - 99.99%Color and Shape:White Crystal PowderMolecular weight:381.90Nexopamil racemate
CAS:Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.Formula:C24H40N2O3Purity:98.61%Color and Shape:SolidMolecular weight:404.59CCR1 antagonist 9
CAS:CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.Formula:C20H16FN5O3SPurity:99.13%Color and Shape:SolidMolecular weight:425.44Ref: TM-T10710
1mg101.00€5mg241.00€10mg402.00€25mg727.00€50mg1,046.00€100mg1,525.00€1mL*10mM (DMSO)265.00€GPR183 antagonist-2
CAS:GPR183 antagonist-2 (compound 32), a selective antagonist of GPR183, exhibits excellent water solubility and pharmacokinetic properties. This compound effectively diminishes paw and joint swelling, and reduces gene expression of pro-inflammatory cytokines (MCP-1, MMPs, and VEGF) in a dose-dependent manner within a collagen-induced arthritis (CIA) mouse model. GPR183 antagonist-2 is applicable in researching autoimmune diseases [1].Formula:C20H18F2N4O5Color and Shape:SolidMolecular weight:432.38SMANT hydrochloride
CAS:SMANT hydrochloride (N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide hydrochloride) is an antagonist of Smoothened accumulation.Formula:C16H24BrClN2OPurity:99.81%Color and Shape:SolidMolecular weight:375.73Enciprazine
CAS:Enciprazine (D-3112) shows anxiolytic activity, is used to treat anxiety disorders, and can be used to study depression.Formula:C23H32N2O6Purity:98.63%Color and Shape:SolidMolecular weight:432.51GPR183-IN-2
CAS:GPR183-IN-2 (compound 23) is an effective, orally active inhibitor of GPR183, displaying an IC50 value of 39.45 nM in Ca2+ mobilization assays. This compound has potential applications in research related to cancer, autoimmune diseases, pain, and osteoporosis.Formula:C19H23BrN2O3Color and Shape:SolidMolecular weight:407.3Zatosetron maleate
CAS:Zatosetron maleate（LY 277359 maleate） is a potent and selective serotonin 5HT3 receptor antagonist for the study of acute migraine.Formula:C23H29ClN2O6Purity:98.07%Color and Shape:SolidMolecular weight:464.94LRH-1 Inhibitor-3
CAS:LRH-1 Inhibitor-3 is an antagonist that inhibits LRH-1 transcriptional activity, reducing SHP, cyclin E1 (CCNE1), and G0S2,antiproliferation anticancer.Formula:C23H25N3O2Purity:98%Color and Shape:SolidMolecular weight:375.46Medroxalol
CAS:Medroxalol (RMI81968), an oral α- & β-adrenergic blocker, has antihypertensive and vasodilatory effects.Formula:C20H24N2O5Color and Shape:SolidMolecular weight:372.42Tecalcet Hydrochloride
CAS:Tecalcet Hydrochloride, an allosteric CaSR modulator, enhances extracellular Ca2+ sensitivity.Formula:C18H23Cl2NOPurity:99.97%Color and Shape:SolidMolecular weight:340.29Ref: TM-T13918
2mg34.00€5mg47.00€10mg72.00€25mg146.00€50mg230.00€100mg335.00€200mgTo inquire1mL*10mM (DMSO)52.00€SARS-CoV-2-IN-57
CAS:SARS-CoV-2-IN-57 (compound (+)-R-26) is a potent inhibitor of SARS-CoV-2 with an IC50 of 80 nM and demonstrates high affinity for the Sigma Receptor, exhibitingFormula:C23H37N3OPurity:98%Color and Shape:SolidMolecular weight:371.56
