GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,002 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(192 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5966 products of "GPCR/G-Protein"
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Femoxetine hydrochloride
CAS:Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.Formula:C20H26ClNO2Purity:99.63%Color and Shape:SolidMolecular weight:347.88SCH-336
CAS:SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.
Formula:C23H25NO8S3Purity:95.01%Color and Shape:SolidMolecular weight:539.64ML 10302 hydrochloride
CAS:ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3.Formula:C15H22Cl2N2O3Purity:99.99%Color and Shape:SolidMolecular weight:349.25SB-277011
CAS:SB-277011A: dopamine D3 antagonist, pKi 8.0 (D3), 6.0 (D2), 5.0 (5-HT1D), <5.2 (5-HT1B).Formula:C28H30N4OPurity:99.39%Color and Shape:SolidMolecular weight:438.56Ref: TM-T12861
1mg47.00€5mg58.00€10mg93.00€25mg158.00€50mg254.00€100mgTo inquire1mL*10mM (DMSO)60.00€ASP-4058
CAS:ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.Formula:C19H12F6N4O2Purity:99.92% - 99.96%Color and Shape:SolidMolecular weight:442.31GW-493838
CAS:GW-493838 is a potent adenosine A1A receptor agonist for the treatment of dyslipidemia and neuropathic pain, with analgesic effects on post-herpetic neuralgiaFormula:C21H21ClFN7O4Purity:99.11% - 99.58%Color and Shape:SolidMolecular weight:489.89Ref: TM-T27509
1mg143.00€5mg346.00€10mg492.00€25mg740.00€50mg999.00€100mg1,350.00€500mg2,647.00€1mL*10mM (DMSO)399.00€Molindone
CAS:Molindone: antipsychotic for schizophrenia; blocks dopamine, often paired with serotonin; dosage affects error/response rates.Formula:C16H24N2O2Purity:99.46% - 99.67%Color and Shape:Off-White SolidMolecular weight:276.37Lensiprazine
CAS:Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder andFormula:C24H27FN4O2Purity:97.86%Color and Shape:SolidMolecular weight:422.5Soquinolol
CAS:Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a longFormula:C17H26N2O3Purity:97.48% - 98.63%Color and Shape:SolidMolecular weight:306.4Medifoxamine
CAS:Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.MedifoxamineFormula:C16H19NO2Purity:98.88%Color and Shape:SolidMolecular weight:257.33Ref: TM-T24444
1mg94.00€5mg222.00€10mg334.00€25mg602.00€50mg845.00€100mg1,099.00€1mL*10mM (DMSO)245.00€OPC-51803
CAS:OPC-51803 is an orally available nonapeptidylpressor (AVP) V(2) receptor selective agonist for the treatment of urinary incontinence and nocturia.Formula:C26H32ClN3O2Purity:98.93% - >99.99%Color and Shape:SolidMolecular weight:454Ancriviroc
CAS:Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.Formula:C28H37BrN4O3Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:557.533Ecastolol
CAS:Ecastolol has anti-angina activity and is an adrenergic receptor antagonist.Formula:C26H33N3O6Purity:99.89%Color and Shape:SolidMolecular weight:483.56Ref: TM-T11148
1mg349.00€5mg697.00€10mg888.00€25mg1,395.00€50mg1,783.00€100mg2,530.00€1mL*10mM (DMSO)880.00€Imiloxan
CAS:Imiloxan (RS-21361) is an α2 adrenergic receptor antagonist used in the treatment of major depressive disorder.Formula:C14H16N2O2Purity:98.13% - 99.8%Color and Shape:SolidMolecular weight:244.29Milenperone
CAS:Milenperone (R 34009) is a novel anti-invasive compound for the control of behavioral disorders in patients with epilepsy and alcoholism.Formula:C22H23ClFN3O2Purity:98.09% - 99.84%Color and Shape:SolidMolecular weight:415.89PPTN hydrochloride
CAS:PPTN hydrochloride is a potent, high-affinity, competitive, highly selective P2Y14 receptor antagonist (KB: 434 pM), but no agonist or antagonist activity atFormula:C29H25ClF3NO2Purity:99.80%Color and Shape:SolidMolecular weight:511.9648740 RP
CAS:48740 RP (RP 55779) is an antagonist of platelet-activating factor.Formula:C12H11N3OSPurity:99.79%Color and Shape:SolidMolecular weight:245.3Ref: TM-T10159
1mg356.00€5mg567.00€10mg907.00€25mg1,339.00€50mg1,815.00€100mg2,432.00€1mL*10mM (DMSO)567.00€Remogliflozin etabonate
CAS:Remogliflozin etabonate is a prodrug SGLT2 inhibitor; Ki for hSGLT2: 1.95μM, rSGLT2: 2.14μM, rSGLT1: 8.57μM, hSGLT1: 43.1μM.Formula:C26H38N2O9Purity:98.98%Color and Shape:SolidMolecular weight:522.59Ref: TM-T34286
2mg34.00€5mg50.00€10mg92.00€25mg156.00€50mg231.00€100mg323.00€200mg447.00€1mL*10mM (DMSO)58.00€Octimibate
CAS:Octimibate: non-prostaglandin antiplatelet, treats cardiovascular disease, aids atherosclerosis/thrombosis research.Formula:C29H30N2O3Purity:99.86%Color and Shape:SolidMolecular weight:454.56Impromidine hydrochloride
CAS:Impromidine hydrochloride is a very potent and specific histamine H2 receptor agonist for conducting cardiovascular studies.Formula:C14H26Cl3N7SPurity:99.82%Color and Shape:SolidMolecular weight:430.83Amosulalol
CAS:Amosulalol is a combined alpha and beta adrenoceptor antagonist.Formula:C18H24N2O5SPurity:99.5%Color and Shape:SolidMolecular weight:380.46Ref: TM-T30027
1mg185.00€2mg279.00€5mg425.00€10mg625.00€25mg938.00€50mg1,311.00€100mg1,795.00€1mL*10mM (DMSO)454.00€NF-56-EJ40
CAS:NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.Formula:C27H29N3O3Purity:99.65%Color and Shape:SolidMolecular weight:443.54L-168049
CAS:L-168049: Human glucagon receptor antagonist, IC50 - 3.7 nM human, 63 nM murine, 60 nM canine.Formula:C24H20BrClN2OPurity:>99.99%Color and Shape:SolidMolecular weight:467.79Ref: TM-T22893
1mg50.00€5mg105.00€10mg170.00€25mg358.00€50mg530.00€100mg758.00€500mg1,558.00€1mL*10mM (DMSO)116.00€KP136
CAS:KP136 is an orally effective antiallergic compound (IC50: 76.1 μg/mL for histamine release and 63 ug/mL for degranulation).Formula:C16H18N4O3Purity:98.3% - 98.61%Color and Shape:SolidMolecular weight:314.34CL 316243
CAS:CL316243 is a highly potent selective agonist of β3-adrenoceptor.Cost-effective and quality-assured.Formula:C20H18ClNNa2O7Purity:98.00% - 99.68%Color and Shape:SolidMolecular weight:465.79BP14979
CAS:BP14979 is D3R-selective partial agonist.Formula:C23H34N4O2Purity:98.29% - 99.73%Color and Shape:SolidMolecular weight:398.54FK-453
CAS:FK-453 is a potent antagonist of non-xanthine adenosine A1 receptor with diuretic and renal vasodilatory activity.Formula:C23H25N3O2Purity:99.44%Color and Shape:SolidMolecular weight:375.46Ronacaleret HCl
CAS:Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.Formula:C25H32ClF2NO4Purity:99.97%Color and Shape:SolidMolecular weight:483.98(R)-ZINC-3573
CAS:ZINC-3573: Potent, selective MRGPRX2 activator; triggers mast cell degranulation and calcium release.
Formula:C18H21N5Purity:99.75%Color and Shape:SolidMolecular weight:307.39AM-1235
CAS:AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.Formula:C24H21FN2O3Purity:99.92%Color and Shape:SolidMolecular weight:404.43Isbogrel
CAS:Isbogrel (CV4151) is a TXA2 synthase inhibitor for researching arrhythmias, ischemic attacks, and thrombosis.Formula:C18H19NO2Purity:99.58%Color and Shape:SolidMolecular weight:281.35Pipoxazole
CAS:Pipoxazole, an adrenergic receptor antagonist, is used potentially for the treatment of depression.Formula:C14H20N4OPurity:98.58% - 99.53%Color and Shape:SolidMolecular weight:260.33GP2-114
CAS:GP2-114 is a catecholamine motility mimetic that produces current-dependent cardiovascular effects.Cost-effective and quality-assured.Formula:C19H24N2O4Purity:99.32%Color and Shape:SolidMolecular weight:344.4SK609 HCl
CAS:SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.Formula:C10H15Cl2NPurity:99.02%Color and Shape:SolidMolecular weight:220.14Repinotan
CAS:Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.Formula:C21H24N2O4SPurity:99%Color and Shape:SolidMolecular weight:400.49Tiospirone
CAS:Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.Formula:C24H32N4O2SPurity:99.74%Color and Shape:SolidMolecular weight:440.6Ref: TM-T24885
1mg123.00€5mg293.00€10mg537.00€25mg863.00€50mg1,161.00€100mg1,558.00€1mL*10mM (DMSO)354.00€AZD1940
CAS:AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.Formula:C20H29F2N3O2SPurity:98.68%Color and Shape:SolidMolecular weight:413.52Ref: TM-T30252
1mg130.00€5mg311.00€10mg535.00€25mg847.00€50mg1,169.00€100mg1,586.00€1mL*10mM (DMSO)344.00€Nemazoline Free Base
CAS:Nemazoline Free Base: a long-lasting nasal decongestant, better than oxymetazoline, with no systemic effects or toxicity in dogs and rats.Formula:C10H11Cl2N3Purity:98.06% - 98.83%Color and Shape:SolidMolecular weight:244.12Felcisetrag
CAS:Felcisetrag (TD-8954), an oral 5-HT4 agonist with GI prokinetic effects, has a high affinity (pKi 9.4) for h5-HT4(c) receptors.Formula:C25H37N5O3Purity:99.99%Color and Shape:SolidMolecular weight:455.59Ref: TM-T28934
1mg87.00€5mg215.00€10mg318.00€25mg510.00€50mg692.00€100mg928.00€200mg1,251.00€1mL*10mM (DMSO)235.00€SB-209670
CAS:SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.Formula:C29H28O9Purity:98.29% - 99.40%Color and Shape:SolidMolecular weight:520.53Ref: TM-T34541
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€1mL*10mM (DMSO)755.00€Cianopramine
CAS:Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.Formula:C20H23N3Purity:99.92% - 99.92%Color and Shape:SolidMolecular weight:305.42(S)-(+)-Niguldipine hydrochloride
CAS:(S)-(+)-Niguldipine hydrochloride is a selective α1A-AR antagonist used in the study of depression and epilepsy.Formula:C36H40ClN3O6Purity:98.27%Color and Shape:SolidMolecular weight:646.17Perphenazine dihydrochloride
CAS:Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.Formula:C21H28Cl3N3OSPurity:99.67%Color and Shape:SolidMolecular weight:476.89Roxindole
CAS:Roxindole: dopamine agonist, serotonin reuptake inhibitor, 5-HT1A agonist, developed for schizophrenia.Formula:C23H26N2OPurity:98.03% - 98.93%Color and Shape:SolidMolecular weight:346.47Compound C108
CAS:Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).
Formula:C15H14N2O3Purity:99.77%Color and Shape:SolidMolecular weight:270.28Evodenoson
CAS:Evodenoson (ATL313), a potent A2aR agonist, treats eye diseases, tumors, and immune disorders; potential for glaucoma and blood cancer studies.Formula:C23H29N7O6Purity:99.75% - 99.83%Color and Shape:SolidMolecular weight:499.52Dimethindene
CAS:Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.Formula:C20H24N2Purity:98.3% - 98.99%Color and Shape:SolidMolecular weight:292.42Quinupramine
CAS:Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.Formula:C21H24N2Purity:99.77%Color and Shape:SolidMolecular weight:304.43CyPPA
CAS:CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.
Formula:C16H23N5Purity:99.88%Color and Shape:SolidMolecular weight:285.39NP10679
CAS:NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.Formula:C23H26F3N3O3Purity:99.43%Color and Shape:SolidMolecular weight:449.47
