GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,997 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(40 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5958 products of "GPCR/G-Protein"
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Milveterol HCl
CAS:Milveterol HCl is a long-acting β(2) -adrenergic receptor agonist for the potential treatment of chronic obstructive pulmonary disease (COPD).Formula:C25H30ClN3O4Purity:99.9%Color and Shape:SolidMolecular weight:471.98FK-453
CAS:FK-453 is a potent antagonist of non-xanthine adenosine A1 receptor with diuretic and renal vasodilatory activity.Formula:C23H25N3O2Purity:99.44%Color and Shape:SolidMolecular weight:375.46ST 91
CAS:ST-91 is an agonist of α2-adrenoceptor with a mixed α-adrenergic receptor type/subtype selection profile.Formula:C13H20ClN3Purity:99.83%Color and Shape:SolidMolecular weight:253.77Ref: TM-T23397
5mg49.00€10mg72.00€25mg142.00€50mg245.00€100mg354.00€200mg497.00€1mL*10mM (DMSO)50.00€Femoxetine hydrochloride
CAS:Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.Formula:C20H26ClNO2Purity:99.63%Color and Shape:SolidMolecular weight:347.88DA-6886
CAS:DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.Formula:C19H28Cl2N6O2Purity:99.91% - 99.99%Color and Shape:SolidMolecular weight:443.37Isbogrel
CAS:Isbogrel (CV4151) is a TXA2 synthase inhibitor for researching arrhythmias, ischemic attacks, and thrombosis.Formula:C18H19NO2Purity:99.58%Color and Shape:SolidMolecular weight:281.35Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Formula:C15H23NOPurity:98.77% - 99.67%Color and Shape:SolidMolecular weight:233.35BMS 182874
CAS:BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.Formula:C17H19N3O3SPurity:99.73%Color and Shape:SolidMolecular weight:345.42DF-1111301
CAS:DF-1111301 is a novel anti-allergic compound with anti-histamine H1 and anti-PAF activity.Formula:C15H25Cl2N3OPurity:99.17%Color and Shape:SolidMolecular weight:334.29Proxyfan
CAS:Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.Formula:C13H16N2OPurity:99.68%Color and Shape:SolidMolecular weight:216.28E6801
CAS:E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.Formula:C17H18ClN5O2S2Purity:96.32% - 97.24%Color and Shape:SolidMolecular weight:423.94CB2R PAM
CAS:CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.Formula:C21H24BrFN2O2Purity:99.09%Color and Shape:SolidMolecular weight:435.33Lensiprazine
CAS:Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder andFormula:C24H27FN4O2Purity:97.86%Color and Shape:SolidMolecular weight:422.5MrgprX2 antagonist-8
CAS:MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.Formula:C24H24ClF3N4O3SPurity:98.61%Color and Shape:SolidMolecular weight:540.99U 99194 maleate
CAS:U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice.Formula:C21H31NO6Purity:99.45%Color and Shape:SolidMolecular weight:393.47Itriglumide
CAS:Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD).Formula:C33H38N2O4Purity:99.95%Color and Shape:SolidMolecular weight:526.67Runcaciguat
CAS:Runcaciguat, a soluble guanylate cyclase stimulator, aids in cardiovascular and renal research.Formula:C23H22Cl2F3NO3Purity:99.17%Color and Shape:SolidMolecular weight:488.33NGD 94-1
CAS:NGD 94-1 is a D4 receptor antagonist that can be used to study psychiatric disorders such as cognitive impairment.Formula:C18H20N6Purity:99.61%Color and Shape:SolidMolecular weight:320.39ASP-4058
CAS:ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.Formula:C19H12F6N4O2Purity:99.92% - 99.96%Color and Shape:SolidMolecular weight:442.31NF-56-EJ40
CAS:NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.Formula:C27H29N3O3Purity:99.65%Color and Shape:SolidMolecular weight:443.54Ticalopride
CAS:Ticalopride: 5-HT3 agonist for digestive, orofacial, ENT disorders, and bulimia, GERD, IBS research.Formula:C14H20ClN3O3Purity:99.51%Color and Shape:SolidMolecular weight:313.785-HT2 antagonist 1
CAS:5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.Formula:C22H29FN4O2Purity:99.76%Color and Shape:SolidMolecular weight:400.49Ref: TM-T12597
1mg642.00€5mg1,288.00€10mg1,738.00€25mg2,583.00€50mg3,484.00€100mg4,708.00€1mL*10mM (DMSO)1,521.00€Litoxetine
CAS:Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.Formula:C16H19NOPurity:99.68%Color and Shape:SolidMolecular weight:241.33Ref: TM-T67956
1mg92.00€5mg207.00€10mg309.00€25mg527.00€50mg755.00€100mg1,044.00€500mg2,088.00€1mL*10mM (DMSO)178.00€Evodenoson
CAS:Evodenoson (ATL313), a potent A2aR agonist, treats eye diseases, tumors, and immune disorders; potential for glaucoma and blood cancer studies.Formula:C23H29N7O6Purity:99.75% - 99.83%Color and Shape:SolidMolecular weight:499.52L-161982
CAS:L-161982 is a selective EP4 receptor antagonist that inhibits PGE2-induced ERK phosphorylation and cell proliferation in HCA-7 cells.Cost-effective and quality-assured.Formula:C32H29F3N4O4S2Purity:99.58% - 99.6%Color and Shape:SolidMolecular weight:654.72Ref: TM-T15681
1mg66.00€5mg122.00€10mg200.00€25mg424.00€50mg608.00€100mg848.00€200mg1,144.00€1mL*10mM (DMSO)170.00€Tildacerfont
CAS:Tildacerfont inhibits CRF1, lowers ACTH/adrenal androgens, and aids in congenital adrenal hyperplasia research.Formula:C20H26ClN5OSPurity:>99.99%Color and Shape:SolidMolecular weight:419.97Neldazosin
CAS:Neldazosin is used as a potent α1-adrenoceptor antagonist.Formula:C18H25N5O4Purity:99.76% - 99.97%Color and Shape:SolidMolecular weight:375.42ANR 94
CAS:ANR94 is a potent hAA2AR antagonist (Ki 46 nM) with potential for Parkinson's research.Formula:C9H13N5OPurity:98.9%Color and Shape:SolidMolecular weight:207.23Ref: TM-T22031
5mg46.00€10mg71.00€25mg130.00€50mg219.00€100mg309.00€200mg434.00€1mL*10mM (DMSO)46.00€GSK299115A
CAS:GSK299115A (GSK-299115A) is a selective ROCK1 Inhibitor. GSK299115A exhibits IC50 of 8nM, 620nM, 560nM for ROCK1, RSK1, p70S6K, respectively.Formula:C20H16Cl2N4O2Purity:99.81%Color and Shape:SolidMolecular weight:415.27Ref: TM-T27471
1mg319.00€5mg772.00€10mg1,074.00€25mg1,596.00€50mg2,147.00€100mg2,822.00€1mL*10mM (DMSO)945.00€Thiethylperazine dimaleate
CAS:Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor.Formula:C30H37N3O8S2Purity:99.88%Color and Shape:SolidMolecular weight:631.76LAS38096
CAS:LAS38096 is an A2B adenosine receptor antagonist (Ki : 17 nM) that is potent, selective and efficient .Formula:C17H12N6OPurity:99.18% - 99.95%Color and Shape:SolidMolecular weight:316.32Dimethindene maleate
CAS:Dimethindene maleate (SU 6518) is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis.Formula:C24H28N2O4Purity:99.79%Color and Shape:SolidMolecular weight:408.49Ref: TM-T21472
1mg34.00€5mg71.00€10mg105.00€25mg236.00€50mg313.00€100mg409.00€200mg582.00€1mL*10mM (DMSO)82.00€SCH-336
CAS:SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.
Formula:C23H25NO8S3Purity:95.01%Color and Shape:SolidMolecular weight:539.64Bavisant
CAS:Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist.Formula:C19H27N3O2Purity:99.21% - 99.65%Color and Shape:SolidMolecular weight:329.44Ref: TM-TQ0046
1mg43.00€5mg96.00€10mg134.00€25mg221.00€50mg325.00€100mg465.00€500mgTo inquire1mL*10mM (DMSO)94.00€CMF019
CAS:CMF019 is a potent agonist of the Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ (pKis: 8.58, 8.49, and 8.71 for the human, rat, and mouse).Formula:C25H33N3O3SPurity:99.5%Color and Shape:SolidMolecular weight:455.61Vadocaine
CAS:Vadocaine (Vadocaina) is a novel analgesic compound for local anaesthesia and can be used to study the central nervous system and cardiovascular system.Formula:C18H28N2O2Purity:99.7%Color and Shape:SolidMolecular weight:304.43ORM-10921
CAS:ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies.Formula:C18H23NO2Purity:99.46% - 99.98%Color and Shape:SolidMolecular weight:285.38Amosulalol
CAS:Amosulalol is a combined alpha and beta adrenoceptor antagonist.Formula:C18H24N2O5SPurity:99.5%Color and Shape:SolidMolecular weight:380.46Ref: TM-T30027
1mg185.00€2mg279.00€5mg425.00€10mg625.00€25mg938.00€50mg1,311.00€100mg1,795.00€1mL*10mM (DMSO)454.00€Tiospirone
CAS:Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.Formula:C24H32N4O2SPurity:99.74%Color and Shape:SolidMolecular weight:440.6Ref: TM-T24885
1mg123.00€5mg293.00€10mg537.00€25mg863.00€50mg1,161.00€100mg1,558.00€1mL*10mM (DMSO)354.00€Butofilolol
CAS:Butofilolol is a novel beta-blocker with antihypertensive activity and can be used to study hypertension.Formula:C17H26FNO3Purity:98.96% - >99.99%Color and Shape:SolidMolecular weight:311.392A-437203
CAS:A-437203 (Lu201640), selective D3 antagonist with Ki: D2-71nM, D3-1.6nM, D4-6220nM; based on 1H-pyrimidin-2-one scaffold.Formula:C20H27F3N6OSPurity:98.80%Color and Shape:SolidMolecular weight:456.53Ref: TM-T10213
1mg94.00€5mg188.00€10mg264.00€25mg411.00€50mg532.00€100mg740.00€200mg982.00€1mL*10mM (DMSO)215.00€cis-Urocanic acid
CAS:cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM).Formula:C6H6N2O2Purity:99.81%Color and Shape:SolidMolecular weight:138.12Bedoradrine
CAS:Bedoradrine (MN-221) free base is a novel, highly selective β2-adrenoceptor agonist.Cost-effective and quality-assured.Formula:C24H32N2O5Purity:>99.99%Color and Shape:SolidMolecular weight:428.52SR144528
CAS:SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).Formula:C29H34ClN3OPurity:99.63%Color and Shape:SolidMolecular weight:476.05D18024
CAS:D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.Formula:C29H31ClFN3OPurity:99.86%Color and Shape:SolidMolecular weight:492.03Ref: TM-T10945
1mg349.00€5mg697.00€10mg888.00€25mg1,395.00€50mg1,783.00€100mg2,530.00€1mL*10mM (DMSO)880.00€Ancriviroc
CAS:Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.Formula:C28H37BrN4O3Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:557.533Compound C108
CAS:Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).
Formula:C15H14N2O3Purity:99.77%Color and Shape:SolidMolecular weight:270.28PD 168568 dihydrochloride
CAS:PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).Formula:C22H29Cl2N3OPurity:99.71%Color and Shape:SolidMolecular weight:422.39Ref: TM-T12383
5mg46.00€10mg55.00€25mg111.00€50mg166.00€100mg235.00€200mg329.00€1mL*10mM (DMSO)57.00€Tedatioxetine
CAS:Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Formula:C18H21NSPurity:99.76% - >99.99%Color and Shape:SolidMolecular weight:283.43Egis-11150
CAS:Egis-11150 is a potent inhibitor of adrenergic alpha1, alpha2c, 5-HT2a, 5HT7 receptors.Formula:C19H21ClFN5O2Purity:97.49% - >99.99%Color and Shape:SolidMolecular weight:405.85
