GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,997 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(40 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5958 products of "GPCR/G-Protein"
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Rafabegron
CAS:Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.Formula:C21H23ClN2O4Purity:99.81%Color and Shape:SolidMolecular weight:402.87Isbogrel
CAS:Isbogrel (CV4151) is a TXA2 synthase inhibitor for researching arrhythmias, ischemic attacks, and thrombosis.Formula:C18H19NO2Purity:99.58%Color and Shape:SolidMolecular weight:281.35SDZ-62-434
CAS:SDZ-62-434 is a platelet-activating factor inhibitor with antitumor activity and may be used in the study of leukemia.Formula:C23H27Cl2N3Purity:98.38%Color and Shape:SolidMolecular weight:416.39L-161982
CAS:L-161982 is a selective EP4 receptor antagonist that inhibits PGE2-induced ERK phosphorylation and cell proliferation in HCA-7 cells.Cost-effective and quality-assured.Formula:C32H29F3N4O4S2Purity:99.58% - 99.6%Color and Shape:SolidMolecular weight:654.72Ref: TM-T15681
1mg66.00€5mg122.00€10mg200.00€25mg424.00€50mg608.00€100mg848.00€200mg1,144.00€1mL*10mM (DMSO)170.00€Nonabine
CAS:Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.Formula:C25H33NO2Purity:99.82% - 99.94%Color and Shape:SolidMolecular weight:379.54SPD-473 citrate
CAS:SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.Formula:C23H31Cl2NO8SPurity:99.37%Color and Shape:SolidMolecular weight:552.47JZP-361
CAS:JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.Formula:C22H20ClN5OPurity:99.82%Color and Shape:SolidMolecular weight:405.88Taprizosin
CAS:Taprizosin（UK-338003） is a selective and orally active α1-adrenoceptor antagonist for vasodilatation in the treatment of benign prostatic hyperplasia.Formula:C25H26N6O4SPurity:98.10% - 99.11%Color and Shape:SolidMolecular weight:506.58Cianopramine
CAS:Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.Formula:C20H23N3Purity:99.92% - 99.92%Color and Shape:SolidMolecular weight:305.42Soquinolol
CAS:Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a longFormula:C17H26N2O3Purity:97.48% - 98.63%Color and Shape:SolidMolecular weight:306.4ML-354
CAS:ML354 is a selective antagonist of PAR4 with an IC 50 of 140 nM [1].Formula:C16H14N2O3Purity:99.44%Color and Shape:SolidMolecular weight:282.29Midaglizole hydrochloride
CAS:Midaglizole hydrochloride (DG5128) is an α2-adrenoceptor antagonist with 7.4x more affinity than α1-adrenoceptors (pKi=6.28).Formula:C16H19Cl2N3Purity:99.39% - 99.82%Color and Shape:SolidMolecular weight:324.25Ref: TM-T11015
1mg54.00€5mg119.00€10mg188.00€25mg306.00€50mg416.00€100mg532.00€200mg705.00€1mL*10mM (DMSO)152.00€Liafensine
CAS:Liafensine(BMS-820836): Selective inhibitor for serotonin, norepinephrine, dopamine reuptake; targets major depression, CNS disorders.Formula:C24H22N4Purity:99.91%Color and Shape:SolidMolecular weight:366.46PF-00217830
CAS:PF-00217830: agonist at serotonin 1A & dopamine D2, antagonist at serotonin 2A, potential schizophrenia study drug.Formula:C26H30N4O2Purity:98.72%Color and Shape:SolidMolecular weight:430.54DA-6886
CAS:DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.Formula:C19H28Cl2N6O2Purity:99.91% - 99.99%Color and Shape:SolidMolecular weight:443.37Molindone
CAS:Molindone: antipsychotic for schizophrenia; blocks dopamine, often paired with serotonin; dosage affects error/response rates.Formula:C16H24N2O2Purity:99.46% - 99.67%Color and Shape:Off-White SolidMolecular weight:276.37LX-2931
CAS:LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.Formula:C9H15N3O5Purity:98.85% - 99.83%Color and Shape:SolidMolecular weight:245.23Irdabisant
CAS:Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.Formula:C18H23N3O2Purity:99.96%Color and Shape:SolidMolecular weight:313.39CYM5181
CAS:CYM5181 is related to the body's immune system and can be used to study multiple sclerosis, transplant rejection, and adult respiratory distress syndrome.
Formula:C17H17N3O3Purity:99.51%Color and Shape:SolidMolecular weight:311.34Bedoradrine
CAS:Bedoradrine (MN-221) free base is a novel, highly selective β2-adrenoceptor agonist.Cost-effective and quality-assured.Formula:C24H32N2O5Purity:>99.99%Color and Shape:SolidMolecular weight:428.525HT6-ligand-1
CAS:5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).Formula:C20H22BrN3O2SPurity:99.24% - 99.93%Color and Shape:SolidMolecular weight:448.38NF-56-EJ40
CAS:NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.Formula:C27H29N3O3Purity:99.65%Color and Shape:SolidMolecular weight:443.54RS 42358-197
CAS:RS 42358-197 (RS 25259-007) is a competitive 5-HT3 receptor antagonist.Formula:C19H23ClN2OPurity:99.70%Color and Shape:SolidMolecular weight:330.85Ref: TM-T20739
1mg158.00€5mg351.00€10mg527.00€25mg783.00€50mg1,054.00€100mg1,414.00€200mg1,908.00€1mL*10mM (DMSO)349.00€NP10679
CAS:NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.Formula:C23H26F3N3O3Purity:99.43%Color and Shape:SolidMolecular weight:449.47SB228357
CAS:SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.Formula:C22H17F4N3O2Purity:99.82%Color and Shape:SolidMolecular weight:431.38R 59-022 hydrochloride
CAS:R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.
Formula:C27H27ClFN3OSPurity:97.7%Color and Shape:SolidMolecular weight:496.045-HT6/7 antagonist 1
CAS:5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
Formula:C22H20FN3O3Purity:98.78% - 99.26%Color and Shape:SolidMolecular weight:393.41Parogrelil Free Base
CAS:Parogrelil Free Base is a phosphodiesterase inhibitor, improves claudication-limited exercise performance in patients with peripheral arterial disease.Formula:C19H18BrClN4O2Purity:99.16% - 99.17%Color and Shape:SolidMolecular weight:449.73Ref: TM-T70793
1mg164.00€2mg234.00€5mg389.00€10mg532.00€25mg820.00€50mg1,063.00€100mg1,423.00€200mg1,945.00€Xamoterol hemifumarate
CAS:Xamoterol hemifumarate is a potent and selective β1-adrenoceptor agonist.Xamoterol hemifumarate is a potential compound for the study of the relationshipFormula:C36H54N6O14Purity:99.79%Color and Shape:White SolidMolecular weight:794.37SR144528
CAS:SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).Formula:C29H34ClN3OPurity:99.63%Color and Shape:SolidMolecular weight:476.05Octimibate
CAS:Octimibate: non-prostaglandin antiplatelet, treats cardiovascular disease, aids atherosclerosis/thrombosis research.Formula:C29H30N2O3Purity:99.86%Color and Shape:SolidMolecular weight:454.56TASP0390325
CAS:TASP0390325, a potent and orally active V1B receptor antagonist, has antidepressant and anxiolytic activities in rodents.Formula:C25H30Cl2FN5O4Purity:98.62%Color and Shape:SolidMolecular weight:554.44E6801
CAS:E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.Formula:C17H18ClN5O2S2Purity:96.32% - 97.24%Color and Shape:SolidMolecular weight:423.94Pipoxazole
CAS:Pipoxazole, an adrenergic receptor antagonist, is used potentially for the treatment of depression.Formula:C14H20N4OPurity:98.58% - 99.53%Color and Shape:SolidMolecular weight:260.33Pirmagrel
CAS:pirmagrel is a potent thromboxane synthase inhibitor.Formula:C13H16N2O2Purity:98.02%Color and Shape:SolidMolecular weight:232.28GBR 12783 dihydrochloride
CAS:GBR 12783 dihydrochloride inhibits dopamine uptake in rats/mice; IC50s: 1.8/1.2 nM. Enhances memory, boosts hippocampal acetylcholine.Formula:C28H34Cl2N2OPurity:98.08%Color and Shape:SolidMolecular weight:485.49rel-(1R,2R)-Vesamicol Hydrochloride
CAS:rel-(1R,2R)-Vesamicol Hydrochloride is a acetylcholine transport inhibitor.Formula:C17H26ClNOPurity:99.88%Color and Shape:SolidMolecular weight:295.85Tiospirone
CAS:Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.Formula:C24H32N4O2SPurity:99.74%Color and Shape:SolidMolecular weight:440.6Ref: TM-T24885
1mg123.00€5mg293.00€10mg537.00€25mg863.00€50mg1,161.00€100mg1,558.00€1mL*10mM (DMSO)354.00€Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Formula:C15H23NOPurity:98.77% - 99.67%Color and Shape:SolidMolecular weight:233.35Butofilolol
CAS:Butofilolol is a novel beta-blocker with antihypertensive activity and can be used to study hypertension.Formula:C17H26FNO3Purity:98.96% - >99.99%Color and Shape:SolidMolecular weight:311.392Nemazoline Free Base
CAS:Nemazoline Free Base: a long-lasting nasal decongestant, better than oxymetazoline, with no systemic effects or toxicity in dogs and rats.Formula:C10H11Cl2N3Purity:98.06% - 98.83%Color and Shape:SolidMolecular weight:244.12Quinupramine
CAS:Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.Formula:C21H24N2Purity:99.77%Color and Shape:SolidMolecular weight:304.43Oxyfedrine L-form HCl
CAS:Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.Formula:C19H24ClNO3Purity:99.5% - 99.57%Color and Shape:SolidMolecular weight:349.85Ref: TM-T24579
1mg92.00€5mg178.00€10mg313.00€25mg485.00€50mg700.00€100mg893.00€200mg1,198.00€1mL*10mM (DMSO)203.00€Tiopinac
CAS:Tiopinac: tricyclic with anti-inflammatory, analgesic, antipyretic properties; inhibits prostaglandin synthesis; mild anti-platelet effects in humans.Formula:C16H12O3SPurity:>99.99%Color and Shape:SolidMolecular weight:284.33ST-1535
CAS:ST 1535: potent, oral A2A adenosine receptor antagonist with antiparkinsonian and antitremor effects, promising for Parkinson's research.Formula:C12H16N8Purity:99.64% - 99.69%Color and Shape:SolidMolecular weight:272.31Edonentan
CAS:Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.Formula:C28H32N4O5SPurity:98.07% - 99.6%Color and Shape:SolidMolecular weight:536.64K6PC-5
CAS:K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels.Formula:C19H37NO4Purity:99.9%Color and Shape:SolidMolecular weight:343.5Teniloxazine
CAS:Teniloxazine is an orally available antidepressant compound with anti-hypoxic properties.Formula:C16H19NO2SPurity:99.29%Color and Shape:SolidMolecular weight:289.39U 99194 maleate
CAS:U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice.Formula:C21H31NO6Purity:99.45%Color and Shape:SolidMolecular weight:393.47Dabelotine
CAS:Dabelotine (UNII-6RY56RB98P) is an adrenergic agonist used in the study of dementia.
Formula:C15H22N2O2Purity:98.55%Color and Shape:SolidMolecular weight:262.35
