GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5964 products of "GPCR/G-Protein"
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SB-215505
CAS:SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, 5-HT2A - 6.77).Formula:C19H16ClN3OPurity:98.33%Color and Shape:SolidMolecular weight:337.8Regrelor disodium
CAS:Regrelor disodium (INS 50589) is a p2y12 receptor antagonist that prevents thrombosis, effectively inhibits vascular smooth muscle cell contraction, inhibitsFormula:C22H23N6Na2O8PPurity:99.89%Color and Shape:SolidMolecular weight:576.41PF-00217830
CAS:PF-00217830: agonist at serotonin 1A & dopamine D2, antagonist at serotonin 2A, potential schizophrenia study drug.Formula:C26H30N4O2Purity:98.72%Color and Shape:SolidMolecular weight:430.54Ordopidine
CAS:Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity.Formula:C14H20FNO2SPurity:97.09%Color and Shape:SolidMolecular weight:285.38ML-354
CAS:ML354 is a selective antagonist of PAR4 with an IC 50 of 140 nM [1].Formula:C16H14N2O3Purity:99.44%Color and Shape:SolidMolecular weight:282.29Enerisant hydrochloride
CAS:Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteinsFormula:C22H31ClN4O3Purity:99.95%Color and Shape:SolidMolecular weight:434.96SR144528
CAS:SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).Formula:C29H34ClN3OPurity:99.63%Color and Shape:SolidMolecular weight:476.05CCG 203769
CAS:CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.Formula:C8H14N2O2SPurity:99.88%Color and Shape:SolidMolecular weight:202.27Ref: TM-T10705
1mg84.00€5mg177.00€10mg250.00€25mg444.00€50mg622.00€100mg893.00€500mg1,783.00€1mL*10mM (DMSO)195.00€Isbogrel
CAS:Isbogrel (CV4151) is a TXA2 synthase inhibitor for researching arrhythmias, ischemic attacks, and thrombosis.Formula:C18H19NO2Purity:99.58%Color and Shape:SolidMolecular weight:281.35CL 316243
CAS:CL316243 is a highly potent selective agonist of β3-adrenoceptor.Cost-effective and quality-assured.Formula:C20H18ClNNa2O7Purity:98.00% - 99.68%Color and Shape:SolidMolecular weight:465.79E6801
CAS:E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.Formula:C17H18ClN5O2S2Purity:96.32% - 97.24%Color and Shape:SolidMolecular weight:423.94APNEA
CAS:APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) is a non-selective agonist of adenosine A3 receptor.Formula:C18H22N6O4Purity:99.88%Color and Shape:SolidMolecular weight:386.41BMS CCR2 22
CAS:BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.Formula:C28H34F3N5O4SPurity:99.65%Color and Shape:SolidMolecular weight:593.66Ref: TM-T14688
1mg55.00€5mg110.00€10mg173.00€25mg349.00€50mg532.00€100mg718.00€200mg964.00€1mL*10mM (DMSO)147.00€SLP9101555
SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 90 nM.SLP9101555 has a high affinity for SphK2, which is 200-fold
Formula:C16H22BrClN2Purity:99.45%Color and Shape:SolidMolecular weight:357.72Ref: TM-T63047
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€JZP-361
CAS:JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.Formula:C22H20ClN5OPurity:99.82%Color and Shape:SolidMolecular weight:405.88Medifoxamine
CAS:Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.MedifoxamineFormula:C16H19NO2Purity:98.88%Color and Shape:SolidMolecular weight:257.33Ref: TM-T24444
1mg94.00€5mg222.00€10mg334.00€25mg602.00€50mg845.00€100mg1,099.00€1mL*10mM (DMSO)245.00€Bedoradrine
CAS:Bedoradrine (MN-221) free base is a novel, highly selective β2-adrenoceptor agonist.Cost-effective and quality-assured.Formula:C24H32N2O5Purity:>99.99%Color and Shape:SolidMolecular weight:428.52AS-35
CAS:AS-35, an oral selective leukotriene antagonist, counters ileum contractions with IC50: 8 nM (LTC4), 4 nM (LTD4), 3 nM (LTE4); shows antiallergic effects.Formula:C21H20N6O4Purity:96.69%Color and Shape:SolidMolecular weight:420.42Perphenazine dihydrochloride
CAS:Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.Formula:C21H28Cl3N3OSPurity:99.67%Color and Shape:SolidMolecular weight:476.89SK609 HCl
CAS:SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.Formula:C10H15Cl2NPurity:99.02%Color and Shape:SolidMolecular weight:220.14KSK68
CAS:KSK68 is a sigma-1 and histamine H3 receptor antagonist with analgesic activity, inhibits H3 receptors and can be used to study pain.Formula:C23H28N2O2Purity:99.11%Color and Shape:SolidMolecular weight:364.48Taprizosin
CAS:Taprizosin（UK-338003） is a selective and orally active α1-adrenoceptor antagonist for vasodilatation in the treatment of benign prostatic hyperplasia.Formula:C25H26N6O4SPurity:98.10% - 99.11%Color and Shape:SolidMolecular weight:506.58SF-22
CAS:SF-22 is a Y2R antagonist with potential anti-inflammatory activity that can be used to study diseases associated with neurological disorders.
Formula:C28H26N2O3SPurity:99.09%Color and Shape:SolidMolecular weight:470.58Viloxazine
CAS:Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activityFormula:C13H19NO3Purity:99.65%Color and Shape:SolidMolecular weight:237.29Ricasetron
CAS:Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used in the study of anxiety disorders and anxiety disorders.Formula:C19H27N3OPurity:99.52%Color and Shape:SolidMolecular weight:313.44Anpirtoline hydrochloride
CAS:Anpirtoline hydrochloride (D-16949 hydrochloride) is a 5-HT1B receptor agonist and 5-HT3 receptor antagonist used in the study of dyskinesia.Formula:C10H14Cl2N2SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:265.20Camonagrel
CAS:Camonagrel is a compound that has inhibitory effects on Prostaglandin E2.Formula:C15H16N2O3Purity:98.71% - 99.25%Color and Shape:SolidMolecular weight:272.3BAY 60-6583
CAS:BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3Formula:C19H17N5O2SPurity:98.46% - 99.8%Color and Shape:SolidMolecular weight:379.44Ref: TM-T14506
1mg39.00€2mg50.00€5mg84.00€10mg116.00€25mg233.00€50mg376.00€100mg567.00€200mg797.00€1mL*10mM (DMSO)101.00€Thonzylamine hydrochloride
CAS:Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.Formula:C16H23ClN4OPurity:99.67%Color and Shape:White Crystalline PowderMolecular weight:322.83Rilapine
CAS:Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders.Formula:C22H20ClN3Purity:97.76% - 99.20%Color and Shape:SolidMolecular weight:361.87GW438014A
CAS:GW438014A 是一种有效且具有选择性的 NPY-Y5 受体拮抗剂。GW438014A 对食物摄入并减少肥胖啮齿动物的体重增加具有抑制作用。Formula:C23H23N3O4SPurity:99.94%Color and Shape:SolidMolecular weight:437.51O-1602
CAS:O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatmentFormula:C17H22O2Purity:99.85%Color and Shape:SolidMolecular weight:258.36Ref: TM-T23097
1mg44.00€5mg95.00€10mg137.00€25mg254.00€50mg358.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)95.00€CGRP antagonist 1
CAS:CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for theFormula:C29H26N4O4Purity:99.55%Color and Shape:SolidMolecular weight:494.54Oxyfedrine L-form HCl
CAS:Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.Formula:C19H24ClNO3Purity:99.5% - 99.57%Color and Shape:SolidMolecular weight:349.85Ref: TM-T24579
1mg92.00€5mg178.00€10mg313.00€25mg485.00€50mg700.00€100mg893.00€200mg1,198.00€1mL*10mM (DMSO)203.00€TASP0390325
CAS:TASP0390325, a potent and orally active V1B receptor antagonist, has antidepressant and anxiolytic activities in rodents.
Formula:C25H30Cl2FN5O4Purity:98.62%Color and Shape:SolidMolecular weight:554.44Amosulalol
CAS:Amosulalol is a combined alpha and beta adrenoceptor antagonist.Formula:C18H24N2O5SPurity:99.5%Color and Shape:SolidMolecular weight:380.46Ref: TM-T30027
1mg185.00€2mg279.00€5mg425.00€10mg625.00€25mg938.00€50mg1,311.00€100mg1,795.00€1mL*10mM (DMSO)454.00€Repinotan
CAS:Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.Formula:C21H24N2O4SPurity:99%Color and Shape:SolidMolecular weight:400.49Roxindole
CAS:Roxindole: dopamine agonist, serotonin reuptake inhibitor, 5-HT1A agonist, developed for schizophrenia.Formula:C23H26N2OPurity:98.03% - 98.93%Color and Shape:SolidMolecular weight:346.47GSK299115A
CAS:GSK299115A (GSK-299115A) is a selective ROCK1 Inhibitor. GSK299115A exhibits IC50 of 8nM, 620nM, 560nM for ROCK1, RSK1, p70S6K, respectively.Formula:C20H16Cl2N4O2Purity:99.81%Color and Shape:SolidMolecular weight:415.27Ref: TM-T27471
1mg319.00€5mg772.00€10mg1,074.00€25mg1,596.00€50mg2,147.00€100mg2,822.00€1mL*10mM (DMSO)945.00€Irdabisant
CAS:Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.Formula:C18H23N3O2Purity:99.96%Color and Shape:SolidMolecular weight:313.39Antihistamine-1
CAS:Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。Formula:C23H24FN5Purity:99.69%Color and Shape:SolidMolecular weight:389.47Linetastine
CAS:Linetastine (TMK-688) inhibits 5-LOX, blocks leukotrienes, counters histamine; researched for asthma, atherosclerosis, ulcers.Formula:C35H40N2O6Purity:99.99%Color and Shape:SolidMolecular weight:584.7BL-1020 Mesylate
CAS:BL-1020 Mesylate (CYP-1020 Mesylate) is a GABA A receptor agonist and D2 antagonist used in studies of neurodegeneration.Formula:C28H45ClN4O11S4Purity:>99.99%Color and Shape:SolidMolecular weight:777.39SB228357
CAS:SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.Formula:C22H17F4N3O2Purity:99.82%Color and Shape:SolidMolecular weight:431.38SCH-336
CAS:SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.
Formula:C23H25NO8S3Purity:95.01%Color and Shape:SolidMolecular weight:539.64BP14979
CAS:BP14979 is D3R-selective partial agonist.Formula:C23H34N4O2Purity:98.29% - 99.73%Color and Shape:SolidMolecular weight:398.54Seridopidine
CAS:Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.Formula:C14H20FNO2SPurity:99.77%Color and Shape:SolidMolecular weight:285.38A-437203
CAS:A-437203 (Lu201640), selective D3 antagonist with Ki: D2-71nM, D3-1.6nM, D4-6220nM; based on 1H-pyrimidin-2-one scaffold.Formula:C20H27F3N6OSPurity:98.80%Color and Shape:SolidMolecular weight:456.53Ref: TM-T10213
1mg94.00€5mg188.00€10mg264.00€25mg411.00€50mg532.00€100mg740.00€200mg982.00€1mL*10mM (DMSO)215.00€2'-MeCCPA
CAS:2'-MeCCPA is an A1AR agonist that inhibits trichothecene-stimulated adenylate cyclase activity and has analgesic activity for the study of HCV.Formula:C16H22ClN5O4Purity:99.93%Color and Shape:SolidMolecular weight:383.83RS 67333 hydrochloride
CAS:RS 67333 hydrochloride is a selective 5-HT4R partial agonist (pKi=8.7) with neuroprotective properties for Alzheimer's research.Formula:C19H30Cl2N2O2Purity:98.78%Color and Shape:SolidMolecular weight:389.36
