GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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Ebopiprant HCl
CAS:Ebopiprant (OBE-022) is an oral, selective PGF2α antagonist for preterm labor, safer than indomethacin.Formula:C30H35ClFN3O5S2Color and Shape:SolidMolecular weight:636.1944FAUC-312
CAS:FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.Formula:C21H26N4Purity:98%Color and Shape:SolidMolecular weight:334.46SGC agonist 1
CAS:SGC agonist 1 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 1 is able to increase solubility and has high cell permeability.Formula:C22H19F2N7OColor and Shape:SolidMolecular weight:435.43SQ 26655
CAS:SQ 26655 is an antagonist of thromboxane A2/prostaglandin H2.Formula:C21H34O4Purity:98%Color and Shape:SolidMolecular weight:350.49AC-099 hydrochloride
CAS:AC-099 hydrochloride is a full agonist of neuropeptide FF2 receptor NPFF2R and a partial agonist of neuropeptide FF1 receptor NPFF1R.Formula:C9H9Cl2F3N4Purity:99.86%Color and Shape:SolidMolecular weight:301.1Flesinoxan HCl
CAS:Flesinoxan HCl is the salt form of Flesinoxan, which is a selective 5-HT1A receptor agonist.Formula:C22H27ClFN3O4Color and Shape:SolidMolecular weight:451.92TRAP-6-IN-1
CAS:TRAP-6-IN-1 inhibits collagen/TRAP-6, IC50: 17.12/11.88 μM, blocks platelet aggregation.Formula:C18H20O3Color and Shape:SolidMolecular weight:284.35Robotnikinin
CAS:Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2.Formula:C25H27ClN2O4Purity:98%Color and Shape:SolidMolecular weight:454.95Carbidine dihydrochloride
CAS:Carbidine, a gamma-carboline derivative, is an atypical antipsychotic that modulates dopamine release and tyrosine hydroxylase activity.Formula:C13H20Cl2N2Purity:98.59%Color and Shape:SolidMolecular weight:275.21717-Phenyl trinor prostaglandin A2
CAS:17-Phenyl trinor prostaglandin A2 is a synthetic analog of prostaglandin [1].Formula:C23H28O4Color and Shape:SolidMolecular weight:368.473Quinotolast sodium
CAS:Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.Formula:C17H12N6NaO3Purity:98%Color and Shape:SolidMolecular weight:371.312NAS-181 free base
CAS:NAS-181 free base is a 5-HT(1B) receptor antagonist.Formula:C19H26N2O4Color and Shape:SolidMolecular weight:346.42RXFP1 receptor agonist-2
CAS:RXFP1 Receptor Agonist-2 (Example 124), an EC50 value of 1 nM [1].Formula:C33H32F7N3O5Color and Shape:SolidMolecular weight:683.61Indacaterol xinafoate
CAS:Indacaterol xinafoate is an ultra-long-acting beta-adrenoceptor agonist.Formula:C35H36N2O6Color and Shape:SolidMolecular weight:580.675-HT2A antagonist 1
CAS:5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.Formula:C26H28N4O2Purity:98%Color and Shape:SolidMolecular weight:428.53CB 65
CAS:CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.Formula:C22H28ClN3O3Purity:99.53%Color and Shape:SolidMolecular weight:417.93H3 receptor antagonist 1
CAS:H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.Formula:C20H28F2N2OPurity:98%Color and Shape:SolidMolecular weight:350.45Naxagolide free base
CAS:Naxagolide is a sustained release formulation. It is a dopamine agonist.Formula:C15H21NO2Purity:98%Color and Shape:SolidMolecular weight:247.33LM-1484
CAS:LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.Formula:C28H24N4O3Purity:98%Color and Shape:SolidMolecular weight:464.52Setipafant
CAS:Setipafant is an antagonist of the platelet-activating factor.Formula:C26H23ClN6O2SPurity:98%Color and Shape:SolidMolecular weight:519.02Ritodrine
CAS:Ritodrine (DU21220) is a β-adrenergic agonist as well as an effective uterine relaxant that can be used in arrest premature labor research[1] [2].Formula:C17H21NO3Color and Shape:SolidMolecular weight:287.359-keto Fluprostenol
CAS:9-Keto Fluprostenol, a potent analog of prostaglandin E2 (PGE2), features structural modifications aimed at enhancing its half-life and potency. It derives from Fluprostenol, a thoroughly researched, potent analog of PGF2α, primarily interacting with the FP receptor. The creation of 9-Keto Fluprostenol through the oxidation at C-9 of Fluprostenol suggests a high affinity for EP receptors, potentially functioning as a PGE2 agonist.Formula:C23H27F3O6Color and Shape:SolidMolecular weight:456.458Indeloxazine hydrochloride
CAS:Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.Formula:C14H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:267.75MB-28767
CAS:MB-28767 is an agonist of prostaglandin E2 (PGE2) receptor.Formula:C22H30O5Color and Shape:SolidMolecular weight:374.47SCH 206272
CAS:SCH 206272 is a potent, orally active antagonist of tachykinin NK(1), NK(2), and NK(3) receptor.Formula:C33H41Cl4N5O4Color and Shape:SolidMolecular weight:713.52Siramesine Fumarate
CAS:Siramesine Fumarate, a sigma receptor agonist, is used potentially for the treatment of generalized anxiety disorder.Formula:C34H35FN2O5Purity:98%Color and Shape:SolidMolecular weight:570.65SSTR5 antagonist 1
CAS:SSTR5 antagonist 1: selective, oral SSTR5 blocker; IC50: 9.6 nM (human), 57 nM (mouse).Formula:C28H34FN3O5Purity:98%Color and Shape:SolidMolecular weight:511.59Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Formula:C17H23NO3Color and Shape:SolidMolecular weight:289.37RXFP1 receptor agonist-6
CAS:RXFP1 receptor agonist-6 (Example 7) serves as an agonist for the RXFP1 receptor and effectively suppresses cAMP production in HEK293 cells that stably expressFormula:C38H32F5N3O7Color and Shape:SolidMolecular weight:737.67Prostaglandin D2 serinol amide
CAS:Prostaglandin D2 serinol amide serves as a mild inhibitor against the hydrolysis of [3H]2-oleoylglycerol [1].Formula:C23H39NO6Color and Shape:SolidMolecular weight:425.566O-Arachidonoyl glycidol
CAS:O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].Formula:C23H36O3Color and Shape:SolidMolecular weight:360.53PF-06748962
CAS:PF-06748962 is a potent and selective lactam-based prostaglandin EP3 receptor antagonist.Formula:C21H21N3O2Color and Shape:SolidMolecular weight:347.41(R)-Casopitant
CAS:(R)-Casopitant ((R)-GW679769), an NK1-receptor antagonist, is used in chemotherapy-induced nausea research.Formula:C30H35F7N4O2Color and Shape:SolidMolecular weight:616.61L-749329
CAS:L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.Formula:C28H29NO8SPurity:98%Color and Shape:SolidMolecular weight:539.6SC 34301
CAS:SC 34301 (Enisoprost), a strong oral PGE1 analog, decreases bacterial translocation and increases burned mice survival.Formula:C22H36O5Color and Shape:SolidMolecular weight:380.52LY3154885
CAS:LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).Formula:C23H23Cl2N3O2Color and Shape:SolidMolecular weight:444.35GSK726701A
CAS:GSK726701A is a new type of prostaglandin E2 receptor 4 (EP4) partial agonist (pEC50: 7.4).Formula:C24H22FNO5Purity:98%Color and Shape:SolidMolecular weight:423.43GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Formula:C17H21ClFNO2Color and Shape:SolidMolecular weight:325.81S1PR1-MO-1
CAS:S1PR-MO-1 is a modulator of sphingosine-1-phosphate receptor and is used to study hyperproliferative inflammatory diseases.Formula:C25H29N3O3Purity:98%Color and Shape:SolidMolecular weight:419.52CB-52
CAS:CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].Formula:C26H43NO3Color and Shape:SolidMolecular weight:417.62L 640035
CAS:L 640035 inhibits human platelet aggregation which is induced by arachidonic acid, collagen, and the prostaglandin-endoperoxide analog of U44069.Formula:C15H12O3SPurity:98%Color and Shape:SolidMolecular weight:272.32MK-1421
CAS:MK-1421 is a potent and selective sstr3 antagonist.Formula:C27H24FN9O2Color and Shape:SolidMolecular weight:525.54Emicerfont
CAS:Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).Formula:C22H24N6O2Purity:98%Color and Shape:SolidMolecular weight:404.46(-)-Isoproterenol hydrochloride
CAS:(-)-Isoproterenol hydrochloride is used as a β-adrenergic receptor agonist in the treatment of bradycardia and as a bronchodilator.Formula:C11H17NO3·CIHColor and Shape:SolidMolecular weight:247.72Binedaline
CAS:Binedaline is a selective norepinephrine reuptake inhibitor with Ki value of 25 nM.Formula:C19H23N3Purity:98%Color and Shape:SolidMolecular weight:293.41TGR5 Receptor Agonist 4
CAS:TGR5 Receptor Agonist 4, a selective agonist for the Bile Acid Receptor (TGR5), exhibits potent activity with an EC50 of 2 nM for human TGR5 (hTGR5) and 3 nMFormula:C25H27ClN2O5Color and Shape:SolidMolecular weight:470.95IWP-051
CAS:IWP-051: potent oral sGC stimulator, >99% protein bound, stable, permeable, no Caco-2 efflux, potential for daily dose.Formula:C17H11F2N5O2Color and Shape:SolidMolecular weight:355.3GLP-1R agonist 12
CAS:GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。Formula:C34H36N6O4Color and Shape:SolidMolecular weight:592.69TGR5 agonist 3
CAS:Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1].Formula:C28H48O5Color and Shape:SolidMolecular weight:464.68MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Formula:C25H26Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:538.85
