GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5696 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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11(Z),14(Z)-Eicosadienoic Acid Ethanolamide
CAS:
- 162758-92-1
11(Z),14(Z)-Eicosadienoic acid ethanolamide is an ethanolamide derivative of 11(Z),14(Z)-eicosadienoic acid.
Formula:C₂₂H₄₁NO₂
Color and Shape:Solid
Molecular weight:351.57
Ref: TM-T85017
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Robotnikinin
CAS:
- 1132653-79-2
Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2.
Formula:C₂₅H₂₇ClN₂O₄
Purity:98%
Color and Shape:Solid
Molecular weight:454.95
Ref: TM-T26110
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15(R)-Prostaglandin E2
CAS:
- 38873-82-4
15(R)-Prostaglandin E2, the C-15 epimer of the more physiologically abundant 15(S)-PGE2 (sc-201225) isomer, is produced mainly from arachidonic acid (sc-200770) via the action of COX and PGES enzymes. Present in nearly all cell types, PGE2 interacts with four distinct receptors, EP1 to EP4, leading to a wide range of biological effects. However, 15(R)-Prostaglandin E2 exhibits significantly lower efficacy in most biological assays compared to its 15(S) counterpart. Notably, acid catalyzed epimerization can transform 15(R)-Prostaglandin E2 into the more active 15(S)-Prostaglandin E2 form.
Formula:C₂₀H₃₂O₅
Color and Shape:Solid
Molecular weight:352.471
Ref: TM-T84587
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Mesembrine
CAS:
- 468-53-1
Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).
Formula:C₁₇H₂₃NO₃
Color and Shape:Solid
Molecular weight:289.37
Ref: TM-T73857
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RXFP1 receptor agonist-8
CAS:
- 2941271-76-5
Example 2 (RXFP1 receptor agonist-8) is a potent RXFP1 receptor agonist that suppresses cAMP production in HEK293 cells expressing human RXFP1, exhibiting an
Formula:C₄₀H₃₆F₅N₃O₇
Color and Shape:Solid
Molecular weight:765.72
Ref: TM-T81239
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Hydroxydione
CAS:
- 303-01-5
Hydroxydione, a neuroactive steroid with general anesthetic properties, is utilized in anesthesia-related research [1] [2].
Formula:C₂₁H₃₂O₃
Color and Shape:Solid
Molecular weight:332.48
Ref: TM-T82146
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BMY-42393
CAS:
- 136451-58-6
BMY-42393 is an oral prostacyclin agonist and platelet aggregation inhibitor with IC50 of 0.3-2μM and stimulates adenylate cyclase (EC50 = 25nM).
Formula:C₂₅H₂₁NO₄
Color and Shape:Solid
Molecular weight:399.44
Ref: TM-T70865
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MK3577
CAS:
- 1019112-29-8
MK3577 is a glucagon receptor antagonist.
Formula:C₃₀H₃₀ClFN₂O₃
Color and Shape:Solid
Molecular weight:521.02
Ref: TM-T28057
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Frovatriptan
CAS:
- 158747-02-5
Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.
Formula:C₁₄H₁₇N₃O
Color and Shape:Solid
Molecular weight:243.3
Ref: TM-T60345
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Droxicam
CAS:
- 90101-16-9
Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal
Formula:C₁₆H₁₁N₃O₅S
Purity:99.04%
Color and Shape:Solid
Molecular weight:357.34
Ref: TM-T27209
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GYKI-46903 HCl
CAS:
- 142999-59-5
GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.
Formula:C₁₇H₂₁ClFNO₂
Color and Shape:Solid
Molecular weight:325.81
Ref: TM-T32033
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LY-368975
CAS:
- 163059-33-4
LY-368975 is a potent and selective inhibitor of the norepinephrine (NE) reuptake site. LY-368975 reduces food consumption in rodents.
Formula:C₁₇H₂₁NOS
Color and Shape:Solid
Molecular weight:287.42
Ref: TM-T27948
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Lidamidine
CAS:
- 66871-56-5
Lidamidine (Lidamidinum) is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle
Formula:C₁₁H₁₆N₄O
Purity:99.98%
Color and Shape:Solid
Molecular weight:220.27
Ref: TM-T25719
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Satigrel
CAS:
- 111753-73-2
Satigrel is a new antiplatelet agent. It also inhibits platelet accumulation in prosthetic arterial grafts.
Formula:C₂₀H₁₉NO₄
Purity:98%
Color and Shape:Solid
Molecular weight:337.37
Ref: TM-T24760
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Quinotolast sodium
CAS:
- 101193-62-8
Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.
Formula:C₁₇H₁₂N₆NaO₃
Purity:98%
Color and Shape:Solid
Molecular weight:371.312
Ref: TM-T13855
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SLIGRL-NH2 TFA
CAS:
- 2828432-39-7
SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1].
Formula:C₃₁H₅₇F₃N₁₀O₉
Color and Shape:Solid
Molecular weight:770.84
Ref: TM-T75902
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Thromboxane A2
CAS:
- 57576-52-0
Thromboxane A2: unstable, leads to thromboxane B2, induces platelet aggregation, causes vasoconstriction.
Formula:C₂₀H₃₂O₅
Color and Shape:Solid
Molecular weight:352.47
Ref: TM-T34862
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CI-949
CAS:
- 104961-19-5
CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).
Formula:C₂₀H₂₀N₆O₃
Purity:98%
Color and Shape:Solid
Molecular weight:392.41
Ref: TM-T10054
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Ro-70-0004
CAS:
- 186386-21-0
Ro-70-0004 is a selective antagonist of alpha1A-adrenoceptor.
Formula:C₂₀H₂₄F₄N₄O₃
Color and Shape:Solid
Molecular weight:444.42
Ref: TM-T28606
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(2R,3S)-E1R
CAS:
- 1424832-60-9
(2R,3S)-E1R, an enantiomer of E1R, is a sigma-1 receptor modulator for treating cognitive disorders.
Formula:C₁₃H₁₆N₂O₂
Purity:98%
Color and Shape:Solid
Molecular weight:232.28
Ref: TM-T10094