GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,037 products)
- Adenosine Receptor(214 products)
- Adrenergic Receptor(3,159 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(63 products)
- CXCR(165 products)
- CaSR(31 products)
- Cannabinoid Receptor(223 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(447 products)
- Endothelin Receptor(85 products)
- GNRH Receptor(88 products)
- GPCR19(38 products)
- GRK(40 products)
- GTPase(24 products)
- Glucagon Receptor(204 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(390 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(54 products)
- Opioid Receptor(334 products)
- PAFR(12 products)
- PKA(57 products)
- S1P Receptor(18 products)
- SGLT(32 products)
- Sigma receptor(48 products)
Show 19 more subcategories
Found 5940 products for "GPCR/G-Protein".
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TGR5 agonist 4
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].Formula:C24H38F2O5Color and Shape:SolidMolecular weight:444.55Iloperidone metabolite P95
CAS:Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Formula:C23H25FN2O5Color and Shape:SolidMolecular weight:428.46VIP(6-28)(human, rat, porcine, bovine)
CAS:VIP(6-28) blocks VIP-induced cAMP signaling in humans, rats, pigs, and cows.Formula:C126H207N37O34SPurity:98%Color and Shape:SolidMolecular weight:2816.2816-phenoxy tetranor Prostaglandin F2α
CAS:16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.Formula:C22H30O6Color and Shape:SolidMolecular weight:390.47Dabelotine, (R)-
CAS:Dabelotine, (R)- is the R-isomer of Dabelotine. Dabelotine is an adrenergic agonist used in the study of dementia.Formula:C15H22N2O2Color and Shape:SolidMolecular weight:262.35Vedaprofen
CAS:Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at IC50 222 μM, Ki 131 μM.Formula:C19H22O2Purity:99.24% - 99.70%Color and Shape:SolidMolecular weight:282.38CCR6 antagonist 1
CAS:CCR6 antagonist 1 blocks CCL20/CCR6, aiding autoimmune and IBD research.Formula:C17H12F3NO2Purity:99.83%Color and Shape:SolidMolecular weight:319.28Ref: TM-T60145
1mg34.00€2mg49.00€5mg74.00€1mL*10mM (DMSO)82.00€10mg105.00€25mg215.00€50mg313.00€100mg484.00€200mg683.00€CUR61414 hydrochloride
CUR61414 hydrochloride: potent cell-permeable Hedgehog pathway inhibitor, IC50=100-200 nM, selectively targets Smo (Ki=44 nM), induces cancer cell apoptosis.Formula:C31H43ClN4O5Purity:94.05%Color and Shape:SolidMolecular weight:587.15Dehydro Aripiprazole (hydrochloride)
CAS:Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.Formula:C23H26Cl3N3O2Color and Shape:SolidMolecular weight:482.83Thromboxane B1
CAS:Thromboxane B1 (TXB1) is a lipid eicosanoid, part of the TXB family, involved in blood clotting.Formula:C20H36O6Color and Shape:SolidMolecular weight:372.5Cenicriviroc Mesylate
CAS:Cenicriviroc Mesylate (TBR-652 Mesylate) is an oral dual CCR2/CCR5 antagonist exhibiting anti-inflammatory and anti-fibrotic effects for liver fibrosis.Formula:C42H56N4O7S2Purity:98.81%Color and Shape:SolidMolecular weight:793.05Ref: TM-T10756
1mg75.00€5mg120.00€1mL*10mM (DMSO)167.00€10mg192.00€25mg385.00€50mg655.00€100mg875.00€TRAP-6 amide
CAS:TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.Formula:C34H57N11O8Color and Shape:SolidMolecular weight:747.899a-Helical Corticotropin Releasing Factor (12-41)
CAS:α-Helical CRF (12-41), a 30-aa analog, curbs CRF's ACTH-stimulating effect.Formula:C152H251N43O47S2Color and Shape:SolidMolecular weight:3497.01TNP-ATP tetrasodium
TNP-ATP is an antagonist of purinergic P2Y1, P2X3, and P2X2/3 receptors, exhibiting IC50 values of 6, 0.9, and 7 nM, respectively, in HEK293 cells expressing human receptors. It reduces acetic acid-induced calcium flux in 1321N1 cells expressing P2X3 and P2X2/3 receptors with IC50 values of 100 and 62 nM, respectively. TNP-ATP also dose-dependently alleviates acetic acid-induced writhing responses in a visceral pain model in mice, with an ED50 of 6.35 µmol/kg.Color and Shape:Odour SolidCCR8 agonist 1
CCR8 agonist1 (Compound 2) is an activator of CCR8 and is applicable in studies related to autoimmune diseases.Formula:C22H29NO3Color and Shape:SolidMolecular weight:355.47YFLLRNP
CAS:YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.Formula:C45H67N11O10Color and Shape:SolidMolecular weight:922.08AG 045572
CAS:AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 isFormula:C30H37NO5Purity:99.96%Color and Shape:White SolidMolecular weight:491.62Pancreatic Polypeptide, human
CAS:Endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.Formula:C185H287N53O54S2Purity:98%Color and Shape:SolidMolecular weight:4181.71Ecraprost
CAS:Ecraprost is used as a prodrug of prostaglandin E1.Formula:C28H48O6Color and Shape:SolidMolecular weight:480.68Benzomalvin C
CAS:Benzomalvin C, isolated from Penicillium, inhibits NK1 receptor and IDO with IC50 of 130 μM, and has a unique epoxide group at C-19/C-20.Formula:C24H17N3O3Color and Shape:SolidMolecular weight:395.418
