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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5938 products of "GPCR/G-Protein"

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  • AFP-07 free acid

    CAS:
    AFP 07 free acid is a 7,7-difluoroprostacyclin derivative. It also acts as a selective and highly potent agonist for the IP receptor.
    Formula:C22H30F2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:412.47
  • AMG-369

    CAS:
    <p>AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.</p>
    Formula:C26H22FN3O2S
    Purity:98.04% - 98.92%
    Color and Shape:Solid
    Molecular weight:459.54
  • Cendifensine

    CAS:
    Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).
    Formula:C14H17Cl2NO
    Color and Shape:Solid
    Molecular weight:286.197
  • Tiprenolol hydrochloride

    CAS:
    Tiprenolol hydrochloride is a β-adrenoceptor (β-adrenoceptor) antagonist. This compound is effective in eliminating ventricular arrhythmias in dogs caused by intravenous administration of adrenaline, following inhalation of halothane.
    Formula:C13H22ClNO2S
    Color and Shape:Solid
    Molecular weight:291.84
  • H-Glu-Thr-OH

    CAS:
    H-Glu-Thr-OH (L-α-Glutamyl-L-threonine) is a dipeptide composed of two amino acids—glutamic acid (Glu) and threonine (Thr)—linked by a peptide bond and functions as an agonist of the extracellular calcium-sensing receptor (CaSR).
    Formula:C9H16N2O6
    Color and Shape:Solid
    Molecular weight:248.23
  • MRGPRX1 agonist 3


    Compound 1f, a potent MRGPRX1 agonist, has an EC50 of 0.22 μM, useful for neuropathic pain studies.
    Formula:C14H11FN2OS
    Color and Shape:Solid
    Molecular weight:274.31
  • (R)-MrgprX2 antagonist-3

    CAS:
    (R)-MrgprX2 antagonist-3 is an antagonist of MrgprX2. It is applicable in the study of inflammatory skin diseases. For more detailed information, please refer to compound E118 in patent document WO2021092240A1.
    Formula:C16H20FN3O2S
    Molecular weight:337.41
  • SGL5213

    CAS:
    <p>SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.</p>
    Formula:C37H55N3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:669.85
  • D3/5-HT receptor modulator-1

    CAS:
    D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.
    Formula:C24H29N3O2
    Color and Shape:Solid
    Molecular weight:391.506
  • FDU-PB-22

    CAS:
    FDU-PB-22, a novel synthetic cannabinoid, undergoes rapid metabolism in human liver microsomes (HLM) with a half-life of 12.4 minutes.
    Formula:C26H18FNO2
    Color and Shape:Solid
    Molecular weight:395.43
  • 1'-Naphthoyl-2-methylindole

    CAS:
    1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 μM.
    Formula:C20H15NO
    Color and Shape:Solid
    Molecular weight:285.34
  • UMB24

    CAS:
    UMB24 is an effective antagonist of the σ2 receptor, exhibiting dissociation constants (Ki values) of 170 nM for the σ2 receptor and 322 nM for the σ1 receptor. This compound mitigates cocaine-induced convulsions and hyperactivity without causing mortality.
    Formula:C17H21N3
    Color and Shape:Solid
    Molecular weight:267.37
  • R-96544 hydrochloride

    CAS:
    5-HT2 receptor antagonist
    Formula:C22H29NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:355.47
  • Zaladenant

    CAS:
    Zaladenant is an adenosine receptor antagonist with antitumor properties.
    Formula:C19H15F3N6O
    Color and Shape:Solid
    Molecular weight:400.357
  • YM-49598 iodide

    CAS:
    YM-49598 iodide is a tachykinin NK-1 receptor antagonist. It inhibits drug-induced bladder contractions in rats with an IC50 of 11 μg/kg.
    Formula:C36H45Cl2IN2O2
    Color and Shape:Solid
    Molecular weight:735.57
  • Thielavin B

    CAS:
    Thielavin B, from Thielavia terricola, inhibits prostaglandin E2 synthesis and reduces rat oedema.
    Formula:C31H34O10
    Color and Shape:Solid
    Molecular weight:566.6
  • hA3AR agonist 1


    hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .
    Formula:C10H14N6OS
    Color and Shape:Solid
    Molecular weight:266.32
  • IMP-1575

    CAS:
    IMP-1575 is a highly effective inhibitor of hedgehog acyltransferase (HHAT), with an IC50 of 0.75 μM when inhibiting purified HHAT. IMP-1575 has potential applications in cancer research.
    Formula:C19H25N3OS
    Molecular weight:343.49
  • LY 215840

    CAS:
    5-HT2/5-HT7 receptor antagonist
    Formula:C24H33N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:395.54
  • CS-003 Free base

    CAS:
    CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.
    Formula:C34H38Cl2N2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.65