GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(3,031 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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3D-Monophosphoryl Lipid A-5 triethylamine
3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) triethylamine is a TLR agonist that acts as an adjuvant for vaccines, enhancing their immunogenicity.Formula:C88H170N3O20PMolecular weight:1621.27Wy 41747
CAS:Wy 41747 is a long-acting somatostatin analogue utilized in research of diabetes mellitus [1].Formula:C73H92N18O16S2Molecular weight:1541.75PNMT-IN-1
PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and anColor and Shape:Odour SolidOnzigolide
CAS:Onzigolide (BIM-23A760) is a dual agonist for D2R and SSTR2 with strong dopamine and somatostatin properties.Formula:C86H116N16O12S4Color and Shape:SolidMolecular weight:1694.21(Iso)-WAY-260022
CAS:(Iso)-WAY-260022 ((Iso)-NRI-022) is a stereoisomer of WAY-260022, a norepinephrine reuptake inhibitor and selective inhibitor of 5-hydroxytryptamine and dopamine transport proteins.Formula:C21H31F3N2O2Purity:97.68% - 99.36%Color and Shape:SoildMolecular weight:400.48[Ala11,D-Leu15]-Orexin B acetate
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).Formula:C122H210N44O37SPurity:98.18%Color and Shape:SolidMolecular weight:2917.31Triamterene
CAS:Triamterene is a barosensitive epithelial sodium channel (ENaC) blocker with a diuretic effect. It can also act as an inhibitor of the TGR5 receptor, reducing GLP-1 secretion and cAMP level increases induced by TGR5 activation in a dose-dependent manner.Formula:C12H11N7Purity:99.77%Color and Shape:Yellow Yellow SolidMolecular weight:253.26Isoprenaline
CAS:Isoprenaline is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Formula:C11H17NO3Purity:99.31%Color and Shape:SolidMolecular weight:211.26CCR6 inhibitor 1
CAS:CCR6 inhibitor 1 selectively blocks CCR6 (0.45 nM in monkeys, 6 nM in humans), aiding in vitro/vivo disease studies.
Formula:C24H23F3N4O3SPurity:99.89%Color and Shape:SolidMolecular weight:504.52AG 045572
CAS:AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 isFormula:C30H37NO5Purity:99.96%Color and Shape:SolidMolecular weight:491.62CCR8 agonist 1
CCR8 agonist1 (Compound 2) is an activator of CCR8 and is applicable in studies related to autoimmune diseases.Formula:C22H29NO3Color and Shape:SolidMolecular weight:355.47Adrenocorticotropic Hormone (ACTH) (4-10), human
CAS:Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .Formula:C44H59N13O10SPurity:98%Color and Shape:SolidMolecular weight:962.09Metipranolol
CAS:Metipranolol (Betamann) is a type of β- Adrenergic receptors（ β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta blocking potentials (pA2) of 8.3 and 8.4, respectively. It is also a potent substituent in the 3H DHA binding assay, with a ligand concentration of 0.7 nM and a Ki of 39 ± 24 nM.Formula:C17H27NO4Purity:98.37%Color and Shape:SolidMolecular weight:309.4W140 HBr
CAS:[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.Formula:C16H28BrN2O4PPurity:99.85%Color and Shape:SoildMolecular weight:423.28Ref: TM-T60204
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€1mL*10mM (DMSO)284.00€Noladin ether
CAS:Noladin ether (2-AG ether) is a cannabinoid CB1 receptor agonist.Formula:C23H40O3Color and Shape:SolidMolecular weight:364.56GRK2-IN-1 hydrochloride (2055990-90-2 free base)
GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).Formula:C24H26ClFN4O4Purity:98%Color and Shape:SolidMolecular weight:488.94FSCPX
CAS:FSCPX is a potent and selective irreversible antagonist of the A1 adenosine receptor (A1AR), exhibiting low nanomolar binding potency.
Formula:C23H27FN4O6SPurity:98%Color and Shape:SolidMolecular weight:506.55rac Desmethyl Citalopram Hydrochloride
CAS:rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.Formula:C19H20ClFN2OPurity:99.24%Color and Shape:SolidMolecular weight:346.83BMY-14802
CAS:BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formula:C18H22F2N4OPurity:99.84%Color and Shape:SoildMolecular weight:348.39Ref: TM-T67739
2mg35.00€5mg52.00€10mg90.00€25mg164.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€Calcitonin-13C6,15N4 TFA
Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.Formula:C1401C5H240N4315NO48S2·5C2HF3O2Color and Shape:SolidMolecular weight:4007.93
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