GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,004 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(192 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(326 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5968 products of "GPCR/G-Protein"
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GLP-1 receptor agonist 8
CAS:GLP-1 receptor agonist 8, potent for diabetes and obesity research, may also study NAFLD.Formula:C34H36ClFN6O4Color and Shape:SolidMolecular weight:647.14[Des-His1,Glu9]-Glucagon amide
CAS:Glucagon blocker with pA2 of 7.2; no agonist effect. Boosts insulin; prevents glucagon-driven hyperglycemia in rabbits and diabetic rats.Formula:C148H221N41O47SPurity:98%Color and Shape:SolidMolecular weight:3358.68ARC 239 dihydrochloride
CAS:ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively).Formula:C24H31Cl2N3O3Purity:99.72%Color and Shape:SolidMolecular weight:480.43BMS-604992 free base
CAS:BMS-604992 (EX-1314), a selective GHSR agonist, binds strongly (ki=2.3 nM), is orally active, and increases rodent food intake.Formula:C24H31N7O5Color and Shape:SolidMolecular weight:497.556FXR/TGR5 agonist 1
CAS:FXR/TGR5 agonist 1 acts as an agonist on both FXR and TGR5 receptors and is utilized for treating fatty liver disease.Formula:C31H32ClN3O3Color and Shape:SolidMolecular weight:530.07GLP-1R agonist 27
GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).Formula:C32H33N5O4SeColor and Shape:SolidMolecular weight:630.6Benzomalvin A
CAS:Benzomalvin A is a filamentous fungal secondary metabolite.Formula:C24H19N3O2Color and Shape:SolidMolecular weight:381.4315-keto Latanoprost
CAS:Latanoprost, a PG analog for ocular pressure, metabolizes into 15-keto latanoprost, a less potent variant reducing intraocular pressure and pupil size.Formula:C26H38O5Color and Shape:SolidMolecular weight:430.58L-threo Lysosphingomyelin (d18:1)
CAS:L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).Formula:C23H49N2O5PColor and Shape:SolidMolecular weight:464.62[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS:Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.Formula:C50H75N15O10Purity:98%Color and Shape:SolidMolecular weight:1046.23Ramelteon metabolite M-II
CAS:Ramelteon M-II binds MT1/MT2 with IC50s: 208/1470 pM; it's the main metabolite and a melatonin receptor agonist.Formula:C16H21NO3Purity:98%Color and Shape:SolidMolecular weight:275.34HTL22562
CAS:HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formula:C40H49N11O5Color and Shape:SolidMolecular weight:763.904tetranor-PGJM
CAS:Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.
Formula:C16H22O6Color and Shape:SolidMolecular weight:310.346Cetirizine Impurity D
CAS:Cetirizine Impurity D, an antihistamine derivative, acts as a long-lasting H1-receptor antagonist with antiallergic effects.Formula:C30H28Cl2N2Color and Shape:SolidMolecular weight:487.46KwFwLL-NH2
CAS:KwFwLL-NH2 is a hexapeptide that serves as a ligand for the ghrelin receptor (ghrelin receptor). This compound acts as a specific inverse agonist for the ghrelin receptor, exhibiting moderate potency (EC50=45.6 nM).Formula:C49H66N10O6Color and Shape:SolidMolecular weight:891.11Sarafotoxin S6b
CAS:non-selective endothelin receptor agonistFormula:C110H163N27O34S5Purity:98%Color and Shape:SolidMolecular weight:2567.96GLP-1R agonist 15
CAS:GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .Formula:C46H47FN8O7SColor and Shape:SolidMolecular weight:874.98Amitraz
CAS:Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.Formula:C19H23N3Purity:99.88%Color and Shape:White/Pale Yellow Crystalline SolidMolecular weight:293.41Adenosine receptor agonist 1
Compound 6m, an A3 adenosine receptor (AR) partial agonist, exhibits a K i value of 6.7 nM as an adenosine receptor agonist.Formula:C12H14ClN5O2SeColor and Shape:SolidMolecular weight:374.68Y1 receptor antagonist 1 formic
H 409-22 isomer formic, a formate salt of Y1 receptor antagonist 1, is an antagonist of the neuropeptide Y1 receptor (neuropeptide Y1 receptor). This compound effectively blocks the actions of the receptor, playing a crucial role in modulating physiological responses.Formula:C29H35N5O5Color and Shape:SolidMolecular weight:533.62
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