Carboxylic Acids

<p>Applications Furan-2-boronic acid<br></p>

<p>Applications Ethyl 4,4-Difluoroacetoacetate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.<br>References Qi, J.L., et al.: Euro. J. Medn. Chem., 46, 934 (2011); Schirlin, D., et al.: J. Enzymes. Inhibition., 1, 243 (1987);<br></p>

<p>Applications Triacontanoic Acid has agricultural applications and is a useful compound in the removal of residual pesticides from fruit via ozone-microbubble treatment.<br>References Li, C., et al.: Food Control, 120, 107548 (2020)<br></p>

<p>Applications 4-Thiazolecarboxylic Acid (cas# 3973-08-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Hydroxycyclohexane-1-carboxylic acid<br></p>

<p>Applications 3,4-Dimethyl-3-cyclopentene-1-carboxylic Acid is a useful intermediate for organic synthesis.<br>References Otake, K., et al.: Chem. Pharm. Bull., 63, 998 (2015); Bartlett, P. D., et al.: J. Am. Chem. Soc., 87, 1297 (1965)<br></p>

<p>Applications Methacrylic Acid And Methyl Methacrylate Copolymer (cas# 25086-15-1) is a useful research chemical.<br></p>

<p>Applications Methyl 2-Bromo-1-cyclopentenecarboxylate is a versatile reactant that can be derived from Cyclopentanone (C988395), which is a compound used in the synthesis of various simple and complex organic compounds. Cyclopentanone is also used in the synthesis of peptidase IV inhibitors for the treatment of type 2 diabetes.<br>References Imamoto, T. et al.: J. Am. Chem. Soc., 112, 5244 (1990); Augeri, D. et al.: J. Med. Chem., 48, 5025 (2005);<br></p>

<p>Applications 2-Acetylthioisobutyric Acid (cas# 135937-96-1) is a compound useful in organic synthesis.<br>References Souers, A., et al.: Bioorg. Med. Chem. Lett., 8, 2297 (1998), Deaton, D., et al.: Bioorg. Med. Chem. Lett., 18, 732 (2008),<br></p>

<p>Applications 5-[2-(Trifluoromethyl)phenyl]-2-furoic Acid is a chemical reagent used in the preparation of novel TRPV1 antagonists. Also used in the preparation of potent inhibitors of FeII and MnII E, coli Methionine Aminopeptidase as antibacterial agents.<br>References Huguet, F. et al.: ChemMedChem. 7, 1020 (2012); Kim, N. et al.: Chem. Asian J., 8, 400 (2013);<br></p>

<p>Applications 2,2-Dimethyl-3-(4-mercaptophenyl)propionic Acid (cas# 887354-80-5) is a compound useful in organic synthesis.<br></p>

<p>Applications (+/-)-Nipecotic Acid (cas# 498-95-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Hydroxy-4-phenylbenzoic Acid is a useful reagent for the preparation of spiro[3,4-dihydro-2H-pyrrolo[1,2-a]pyrazine-1,4'-piperidine] derivatives as modulators of sodium ion channel.<br>References Hadida Ruah, S. S., et al.: U.S. Pat. Appl. Publ. (2012), US 20120196869 A1<br></p>

<p>Applications Trimethyl Bromoorthoacetate is an intermediate in the synthesis of 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid (B444100), an impurity of Clavulanic Acid (C563750).<br>References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003),<br></p>

<p>Applications 5-Oxo-1,3-dioxolane-4,4-diacetic Acid is used as a reagent to synthesize vibrioferrin, a siderophore. It can also be used as a building block of lipophilic isosteres of nucleoside triphosphates which are potential inhibitors of HIV reverse transcriptase.<br>References Takeuchi, Y., et al.: Chem. Pharm. Bull., 47, 459 (1999); Weaver, R., et al.: Bioorg. Med. Chem. Lett., 6, 2405 (1996)<br></p>

<p>Applications Methyl 2-(2-Hydroxyphenyl)acetate is used as a reactant in the preparation of caffeic acid phenylethyl esters as  antiproliferative agents.<br>References Xie, Jin, et al.: Bioorg. &amp; Med. Chem. Let., 27(2), 131-134 (2017)<br></p>

<p>Applications A more base-stable alternative to Ellman’s reagent for the quantification of thiol contents and enzymatic assays under basic pH conditions. . It reacts with free thiols similar to Ellman’s reagent but has dramatically improved stability under alkaline conditions, making it an excellent alternative to Ellman’s reagent.<br>References Zhang, H., et al.: Bioorg. Chem., 26, 356 (1998), Chen, Y., et al.: Biochem., 43, 11491 (2004),<br></p>

<p>Applications 5-Hexynoic Acid<br></p>

<p>Applications Pentachlorophenyl Cyanoacetate is an intermediate used in the synthesis of Cefacetrile (C231500), which is a cephalosporin antibiotic. Antibacterial.<br>References Dajan, A., et al.: Vet. Microbiol., 35, 213 (1993), Becker, M., et al.: Anal. Chim. Acta, 520, 19 (2004), El-Shaboury, S., et al.: J. Pharm. Biomed. Anal., 45, 1 (2007),<br></p>

<p>Applications A reagent used in the synthesis of glycidol, a stabilizer in manufacturing of vinyl polymers; intermediate in synthesis of glycerol, glycidyl ethers, and amines; additive for oil and synthetic hydraulic fluids; epoxy resin diluent.<br>References Palomo, J.M. et al.: Tetrahedron Asymm., 16, 869 (2005); Hiles, R.A., et al.: Food Cosmet. Toxicol., 19, 347 (1981); Thompson, E.D., et al.: Food Chem. Toxicol., 22, 665 (1984);<br></p>

<p>Applications 4-Hydroxy-3,5-dimethylbenzoic Acid is used in the synthesis of Mexiletine (M340800) derivatives as orally bioavailable inhibitors. Also, used as a chemical reagent in the preparation of potent transthyretin (TTR) amyloidogenesis inhibitors affecting thyroid hormone.<br>References Frederickson, M. et al.: J. Med. Chem., 51, 183 (2008); Johnson, S. et al.: J. Med. Chem., 51, 260 (2008);<br></p>

<p>Applications 6-chloro-imidazo[2,1-b]thiazole-5-sulfonic acid amide (cas# 112582-89-5) is a useful research chemical.<br></p>

<p>Applications rel-N-[(1R,4R)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]carbamic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of the HIV reverse transcriptase inhibitor ziagen.<br>References Grumann, A., et al.: Tetrahedron. Lett., 36, 7767 (1995);<br></p>

<p>Stability Hygroscopic<br>Applications tert-Butyl (((mesityl)sulfonyl)oxy)carbamate is a useful reagent for the enantioselective aziridination of α,β-unsaturated aldehydes.<br>References Arai, H., et l.: Tetrahedron Lett., 50, 3329(2009)<br></p>

<p>Applications Methyl Phenylacetate is used as a reagent in the synthesis of various organic reactions, one of which is the synthesis of Vulpinic Acid (V850000); a lichen metabolite with anti-inflammatory properties.<br>References Shachak, M., et al.: Science, 236, 1098 (1987); Froberg, L., et al.: Lichenologist, 25, 83 (1993); Hesbacher, S., et al.: J. Chem. Ecology, 21, 233 (1995)<br></p>

<p>Applications Used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.<br>References Leeman, M. et al.: Angew. Chem. Int. Ed., 47, 1287 (2008); Eur. J. Med. Chem., 45, 3564 (2010);<br></p>

<p>Applications Ethyl 2-(2,6-Dichlorophenyl)acetate (cas# 90793-64-9) is a useful research chemical.<br></p>

<p>Stability Epimerize in solution<br>Applications 5-Hydroxy-1,3-oxathiolane-2-carboxylic Acid is used in the synthesis of potent antiviral agent (-)-2’-Deoxy-3’-thiacytidine and its enantiomer.<br>References Jin, H.L., et al.: J. Org. Chem., 60, 2621 (1995);<br></p>

<p>Stability Air Sensitive<br>Applications methyl 2-(2-formylphenyl)acetate (cas# 63969-83-5) is a useful research chemical.<br></p>

<p>Applications Used for production of peptide thioester.<br>References Gaeta, A., et al.: Bioorg. Med. Chem. Lett., 20, 4649 (2010),<br></p>

<p>Applications 9-Acridinecarboxylic acid is used in the synthesis of short DNA-binding peptides.<br></p>

<p>Applications 3-FERROCENOYLPROPIONIC ACID (cas# 1291-72-1) is a useful research chemical.<br></p>

<p>Applications 5-(3-Benzyloxyphenyl)nicotinic acid<br></p>

<p>Applications 2-Carboxyfuran-5-boronic acid, pinacol ester<br></p>

<p>Applications 5-Chlorohexanoic acid CAS#: 112176-22-4 is a building block used in organic synthesis.<br>References Liang, S., et al., Green Chemistry., 20, 680 (2018)<br></p>

<p>Applications Allylboronic acid pinacol ester<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (R)-Benzyl (3-Oxo-1-(phenylthio)heptan-2-yl)carbamate is a derivative of N-Carbobenzyloxy-3-phenylthio-L-alanine (C176530) which is an intermediate in the synthesis of Nelfinavir.<br>References Kaldor, S., et al.: J. Med. Chem., 40, 3979 (1997),<br></p>

<p>Applications 2-amino-3-hydroxy-3-phenylpropanoic acid (cas# 7695-56-9) is a useful research chemical.<br></p>

<p>Applications 3-(N,N-Dimethylamino)phenylboronic Acid (cas# 178752-79-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications tert-Butyl 2-(3-Aminophenyl)acetate can be used as anti-heparanase to treat diseases and disorders associated with heparanase activity.<br>References Giannini, G., et.al.: PCT Int. Appl., 103, (2018);<br></p>

<p>Applications (6,7-dimethoxy-4-oxoquinazolin-3(4H)-yl)acetic acid (cas# 877140-09-5) is a useful research chemical.<br></p>

<p>Applications 3-(2-Aminoethoxy)propionic Acid (cas# 144942-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications tert-butyl 2-ethynylmorpholine-4-carboxylate (cas# 1416229-07-6) is a useful research chemical.<br></p>

<p>Please enquire for more information about Methyl 4-methoxy-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Aluminum diacetate hydroxide is a white powder that is soluble in water. It is used as a laser ablation material and can be used to seal chemical reactions. Aluminum diacetate hydroxide also functions as a gas sensor, with its sensitivity to aromatic hydrocarbons and fatty acids. This compound has clinical use in detergent compositions, where it prevents the formation of foam.</p>

<p>Glycerolipid metabolism component</p>

<p>Please enquire for more information about rac-cis despropionyl mefentanyl N-trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Isopropoxyphenylboronic acid is a boronic acid that can be used as a cross-coupling partner in palladium-catalyzed cross-coupling reactions. It is synthesized by reacting 4-hydroxyphenylacetic acid with 2 equivalents of naphthoquinone diazide. The addition of the 4-isopropoxy group to the phenyl substituent increases the reactivity of this boronic acid. This compound has been used in the synthesis of rofecoxib and cyclooxygenase inhibitors, such as aspirin and ibuprofen. The presence of an electron withdrawing group on one phenyl ring enhances the reactivity of this boronic acid towards nucleophiles, such as amines or alcohols.</p>

<p>L-Aspartic acid alpha-tert-butyl ester is a synthetic amino acid that can be used as a substrate for the synthesis of L-cysteine in the presence of selenomethionine. This compound is an auxotroph and cannot be synthesized by the body, so it must be obtained through diet or supplementation. It has been shown to have anti-cancer properties, which may be due to its role in regulating cell proliferation, apoptosis, and angiogenesis. L-Aspartic acid alpha-tert-butyl ester may also inhibit colon cancer cells by preventing them from recycling proteins. This compound was shown to inhibit HCT116 human colon cancer cells in both experimentally and computationally studies. Additionally, this molecule was seen to induce tumor regression in mice with colitis by inhibiting eukaryotic protein synthesis. This inhibition was found to be mediated through a trifluoromethyl group on the molecule's</p>

<p>(2,4-Dimethylphenyl)boronic acid is an arylboronic acid that is used in organic synthesis. The boron atom of the 2,4-dimethylphenyl group coordinates with the metal atom in the catalyst to form a stable complex. This allows for a multilayer reaction and fluorescence to occur. The activated fluorine atoms can be used to boost the reaction by adding them to the substrate and increasing the rate of oxidation. Astragalus membranaceus and rapeseed extracts have been shown to increase the rate of oxidation as well as inhibiting the formation of disaccharides. These extracts also have shown anti-inflammatory effects when tested on rats. (2,4-Dimethylphenyl)boronic acid has also been found to interact with dihydroisoquinolines, which are compounds that are structurally similar to morphine and codeine.</p>

<p>Please enquire for more information about tert-Butyl 4-(2-oxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-1-yl)piperidine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-(2-Oxopyrrolidin-1-yl)benzoic acid (4-OPBA) is a hydrogen bonding inhibitor that is used to study the interactions of cavity proteins. It has shown to interact with glutathione and prostaglandin D2, which are important for hematopoietic and inflammatory responses. 4-OPBA has been observed to bind with a water molecule in the cavity, which may explain its affinity for these molecular targets. The crystal structure of 4-OPBA shows that it forms an interaction with two water molecules and one other molecule in the cavity. This may be due to its ability to form hydrogen bonds with both water molecules as well as the molecule in the cavity.</p>

<p>Please enquire for more information about D-Glyceric acid calcium dihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethylcyclobutanecarboxylate is an organic compound that is used as a drug for the treatment of cancer. It has been shown to inhibit cholesterol ester transfer and has been used in the treatment of pancreatitis, autoimmune diseases, dyslipoproteinemia, and inflammatory diseases. This drug has been shown to reduce insulin resistance and can be used as a treatment for diabetes-associated complications. Ethylcyclobutanecarboxylate is also metabolized into a pharmacologically active form by cb2 receptor. The biological samples that have been studied include plasma and urine; however, it can also be detected in other types of tissue such as brain, stomach, and kidney.</p>

<p>Please enquire for more information about alpha,alpha-Difluorophenylacetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Diethyl 1-[2-(1H-indol-3-yl)ethyl]-2,5-dimethyl-1H-pyrrole-3,4-dicarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (trans)-2-Cyclopropylvinylboronic acid pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Cyano-2-methylphenylboronic acid, pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 8-Ethyl-1,3,4,9-tetrahydro-1-(1-methylethyl)pyrano[3,4-b]indole-1-acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Boc-L-aspartic acid 4-tert-butyl ester is a synthetic aminoacylase that is used in the synthesis of ergosterol. It is an efficient and economical reagent for the preparation of esters of aspartic acid, which are used in fungal antifungal agents. Boc-L-aspartic acid 4-tert-butyl ester has been shown to have various physiological functions, including the ability to inhibit ergosterol synthesis by inhibiting the enzyme polymeric ergosterol synthase in fungi. This compound can also be used to synthesize n-substituted aspartates.</p>

<p>Please enquire for more information about 1-Boc-4-aminopiperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Gibberellic acid methyl ester is a specialized plant growth regulator, which is synthetically derived from the naturally occurring gibberellins found in plants. These gibberellins are vital phytohormones that regulate various aspects of growth and development in higher plants. Gibberellic acid methyl ester functions by mimicking these natural gibberellins, interacting with plant cellular processes to stimulate and enhance growth. Its mode of action involves promoting cell elongation, division, and differentiation, thereby accelerating plant growth and influencing the lifecycle.</p>

<p>Please enquire for more information about 17-Methylestra-3,5-diene-3,17b-diol diacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Eltrombopag olamine is an orally active drug that belongs to the class of thiazolidinones. It has been used for the treatment of thrombocytopenia in patients with chronic liver disease and myelodysplastic syndrome. Eltrombopag olamine inhibits platelet aggregation by binding to glycoprotein IIb/IIIa receptors on the surface of platelets. The drug is a prodrug that is metabolized in vivo to its active form, eltrombopag. This conversion is catalysed by CYP3A4 and CYP2D6 enzymes and can be inhibited by drugs that inhibit these enzymes, such as trifluoroacetic acid and hydroxyl group-containing compounds. Eltrombopag olamine binds to erythrocytes, which may be due to its ability to form intramolecular hydrogen bonds with nitrogen atoms. The synthesis of elt</p>

<p>3,5-Di-tert-butyl-4-hydroxyphenylacetic acid (BHT) is an antiaging agent that has been used in food packaging and cosmetics. BHT is a functionalized triethoxysilane with phenyl groups attached to the silicon atoms. BHT is an antioxidant that protects against lipid peroxidation and prevents the formation of free radicals by reacting with peroxy radicals. It has been shown to have a protective effect on skin cells when applied topically. BHT also has protective effects against environmental stressors such as UV radiation, ozone, and cigarette smoke.</p>

<p>Please enquire for more information about 4-Chloro-3,5-difluorobenzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is an antimicrobial agent that inhibits bacterial growth by binding to the penicillin binding protein (PBP), which prevents the synthesis of peptidoglycan. This drug has shown effectiveness against gram positive bacteria, including aerobacter aerogenes, as well as infectious diseases in wastewater treatment plants. It has also been demonstrated to be effective in experimental models of infection due to high resistance and cell signaling pathways. The reaction solution was analyzed by plasma mass spectrometry.</p>

<p>4-Chloro-6-methylnicotinic acid (4C6MNA) is a chemical substance that is used in the study of plant leaves and their permeability. This substance has been found to be an excellent indicator of chlorophyll content, as it stains leaf cells with a green color. 4C6MNA is taken up by healthy plant cells and mitochondria, where it binds to the chromophore molecule in the mitochondria. The binding of 4C6MNA to the chromophore molecule leads to the production of fluorescence, which can be detected via microscopy. This substance has been used for laser microbeam studies on natural leaves and tobacco plants.</p>

<p>Please enquire for more information about 3-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)isoxazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The 4-chloro-benzenesulfinic acid sodium salt is a type of sulfinic acid. It can be used to control experiments involving methides, halides, and human macrophages. Sodium salts of this compound have been shown to inhibit the growth of Candida glabrata and Galleria mellonella in vitro. The 4-chloro-benzenesulfinic acid sodium salt reacts with chloride ion to form a nucleophilic trifluoroacetate anion, which reacts with thiosulfonates to produce type strain. Trifluoroacetic acid is used as a solvent in the reaction.</p>

<p>Please enquire for more information about (D-His1)-Exenatide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Bromo-2-methylbenzoic acid is a nucleophilic compound that can be used for the synthesis of esters, amides and peptides. It is also an intermediate in the synthesis of 4-bromo-2-methylbenzoic acid methyl ester, which can be used as a cardiac marker. The hydroxylamine group on this molecule reacts with electrophiles such as benzoate to form bromoacetic acid derivatives. This reaction is catalyzed by palladium and other metals. The multidimensional nature of this reaction means it can be used for cross-coupling reactions.</p>

<p>Please enquire for more information about 1-(3-Chloro-2-methylphenyl)-5-oxopyrrolidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Phenobarbital-1-butyric acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride is an optical, amide, and epoxidation derivatizing agent that is used to chiralify amines. It is a liquid at room temperature with a molecular weight of 123.87 g/mol. This chemical reacts with alcohols to form esters, which can be identified by their different retention times in chromatography. It also reacts with hydroxyl groups to form ethers and esters, as well as hydroxyls on other molecules such as amino acids, peptides, and proteins. S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride has been used for the synthesis of bisoprolol from metoprolol and triethylphosphite.</p>

<p>4b-Hydoxy cholesterol 4-acetate is a pleiotropic drug with a wide range of pharmacological activities. It is an inhibitor of the sirtuin family of proteins and may have anti-cancer effects. It has also been shown to be effective in the treatment of depression and myelodysplastic syndrome. The mechanism of action for this agent is not well understood, but it may be due to its ability to inhibit DNA methyltransferases, which would lead to a change in DNA methylation patterns. 4b-Hydroxy cholesterol 4-acetate has also been shown to decrease lipid levels in the blood and increase the activity of liver enzymes that metabolize fatty acids. This drug can also modify lamellar bodies and short-chain fatty acids by inhibiting the enzyme ATP citrate lyase, which catalyzes citrate cleavage into acetyl CoA and oxaloacetate.</p>