Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65576 products of "Quinazoline and Quinoline Derivatives"
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3,4-Dihydro-7-hydroxyquinoline-2(1H)-one
CAS:Formula:C9H9NO2Color and Shape:NeatMolecular weight:163.17Sitagliptin Monohydrochloride Monohydrate
CAS:<p>Applications Sitagliptin Monohydrochloride Monohydrate has therapeutic applications and is used in pharmaceutical compositions in the form of immediate release tablets.<br>References Arroyo Hidalgo, S., & Pladevall Roses, M.: PCT Int. Appl. (2015), WO 2015114152 A1<br></p>Formula:C16H15F6N5O·HCl·H2OColor and Shape:NeatMolecular weight:407.31 + 36.46 + 18.02(S)-4-Nitrophenyl 1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS:Controlled Product<p>Applications (S)-4-Nitrophenyl 1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate is a reactant in the synthesis of solifenacin succinate, an antimuscarinic agent.<br>References Niphade, N.C., et. al.: Monatshefte fuer Chemie, 142, 1181 (2011)<br></p>Formula:C22H18N2O4Color and Shape:NeatMolecular weight:374.396-Bromo-2-chloro-4-phenyl-quinazoline
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:319.5899963378906Tolcapone
CAS:Controlled Product<p>Applications Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian.<br>References Dingemanse, J., et al.: Clin. Pharmacol. Ther., 57, 508 (1995), Keating, K.A., Drugs, 19, 165 (2005),<br></p>Formula:C14H11NO5Color and Shape:ColourlessMolecular weight:273.246-Hydroxy-2-mercaptobenzimidazole
CAS:Controlled ProductFormula:C7H6N2OSColor and Shape:NeatMolecular weight:166.20Mirtazapine-d4
CAS:Controlled Product<p>Applications Mirtazapine-d4 is the labeled analogue of Mirtazapine (M365000), which is an α2-Adrenergic blocker, analogue of Mianserin, and antidepressant.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990);<br></p>Formula:C17H15D4N3Color and Shape:White To Light YellowMolecular weight:269.38Atipamezole
CAS:<p>Atipamezole (Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.</p>Formula:C14H16N2Purity:99.88%Color and Shape:Off-White To Light Yellow Crystal PowderMolecular weight:212.29Oxyphenbutazone-d9
CAS:Controlled ProductFormula:C192H9H11N2O3Color and Shape:BeigeMolecular weight:333.43Decloxizine Dihydrochloride
CAS:Controlled Product<p>Impurity Hydroxyzine EP Impurity B<br>Applications Decloxizine Dihydrochloride (Hydroxyzine EP Impurity B) is a Hydroxyzine (H996500) impurity.<br>References Lulling, J., et al.: Medicina Pharmacol. Exp., 16 48 (1967),<br></p>Formula:C21H28N2O2·2ClHColor and Shape:NeatMolecular weight:413.381,3-Bis(9H-carbazol-4-yloxy)-2-propanol(Carvedilol Impurity)
CAS:Controlled Product<p>Applications A carvedilol Impurity.<br></p>Formula:C27H22N2O3Color and Shape:NeatMolecular weight:422.48(-)-trans-Phenothrin
CAS:<p>Applications (-)-trans-Phenothrin is used in exhaustive parallel conformational search of pyrethroids and structural similarity study. Also used as an active compound combination having insecticidal properties, a synthetic reagent in the preparation and optical purity of benzylic ester pyrethroid enantiomers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bertok, B., et al.: J. Environ. Sci. Health, Part B., 31, 495 (1996); Chuman, H., et al.: Journal of Chemical Software, 4, 143 (1998); Thielert, W., et al.: PCT Int. Appl. (2015), WO 2015132140 A1 20150911;<br></p>Formula:C23H26O3Color and Shape:Colourless To YellowMolecular weight:350.451,4-bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
CAS:Controlled Product<p>Impurity Aripiprazole Diquinoline Butanediol Impurity (USP)<br>Applications An impurity found in the process for the preparation of Aripiprazole (A771000). Aripiprazole Diquinoline Butanediol Impurity (USP).<br>References Burris, K., et al.: J. Pharmacol. Exp. Ther., 302, 381 (2002), Harrison, T., et al.: Drugs, 64, 1715 (2004),<br></p>Formula:C22H24N2O4Color and Shape:Off-WhiteMolecular weight:380.444-(thiophen-3-yl)-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-6-carboxylic acid
CAS:Purity:95.0%Molecular weight:249.28999328613282-Methylimidazole
CAS:<p>Applications 2-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 2-Methylimidazole as well as other imidazoles can be use as catalyst for refolding of enhanced coloured fluorescent protein. 2-Methylimidazole has been identified as a byproduct of fermentation and is detected in foods and mainstream and side-stream tobacco smoke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, R. et al.: Arch. Biochem. Biophys., 459, 122 (2007); Chan, P.C. et al.: Arch. Toxicol., 82, 399 (2008); Nishie, K. et al.: Toxicol. Appl. Pharmacol., 14, 301 (1969);<br></p>Formula:C4H6N2Color and Shape:NeatMolecular weight:82.10R-(-)-N-Demethyl Deprenyl-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Deprenyl (D288641) (Selegiline).<br>References Dyck, L., et al.: Drug Metab. Dispos., 29, 1156 (2001), Damaj, M., et al.: J. Pharmacol. Exp. Ther., 320, 250 (2007),<br></p>Formula:C12H10D5NColor and Shape:NeatMolecular weight:178.294,7-dimethoxy-N-(pyridin-4-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:301.3599853515625rac-Paroxetine-d4 Hydrochloride
CAS:Controlled Product<p>Applications rac-Paroxetine-d4 Hydrochloride is a racemic labeled analogue of Paroxetine Hydrochloride (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978); Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982)<br></p>Formula:C19H17D4ClFNO3Color and Shape:White To Light BrownMolecular weight:369.85Gabapentin Related Compound B
CAS:<p>Impurity Gabapentin EP Impurity B; Gabapentin USP Related Compound B<br>Applications Gabapentin Related Compound B (Gabapentin EP Impurity B; Gabapentin USP Related Compound B) is a Gabapentin analogue for treatment of neurological disorders.<br>References Sit, S., et al.: J. Med. Chem., 33, 2982 (1990), O'Brien, P., et al.: J. Med. Chem., 37, 1810 (1994), Bryans, J., et al.: Med. Res. Rev., 19, 149 (1999),<br></p>Formula:C9H13NO2Color and Shape:NeatMolecular weight:167.20Tert-Butyl-4-(isoquinolin-5-yl)piperazine-1-carboxylate
CAS:Purity:97%Molecular weight:313.4010009765625Pefloxacin Mesylate
CAS:Controlled Product<p>Applications Pefloxacin is a fluorinated quinolone antibacterial; analog of Norfloxacin.<br>References Barre, J., et al.: J. Pharm. Sci., 73, 1379 (1984), Contrepois, A., et al.: J. Antimicrob. Chemother., 14, 51 (1984),<br></p>Formula:C17H20FN3O3·CH4O3SColor and Shape:Off-WhiteMolecular weight:429.4610,11-Dihydro-10-hydroxy Carbamazepine-D4 (Major)
CAS:Controlled ProductFormula:C152H4H10N2O2Color and Shape:BrownMolecular weight:258.312-(5-cyclopropyl-3-(thiophen-2-yl)-1H-pyrazol-1-yl)acetonitrile
CAS:Purity:95.0%Molecular weight:229.3000030517578Nafronyl
CAS:<p>Applications Nafronyl is a selective inhibitor of serotonin receptors. Nafronyl is a vasodilator used in the treatment of intermittent claudication.<br>References Fontaine, et al.: Chim. Ther., 4, 44 (1969), Bessin, P., et al.: Eur. J. Med. Chem., 10, 291 (1975), Clyne, C.A., et al.: Br. J. Surg., 67, 347 (1980),<br></p>Formula:C24H33NO3Color and Shape:NeatMolecular weight:383.52Thioridazine Disulfoxide
CAS:Controlled ProductFormula:C21H26N2O2S2Color and Shape:NeatMolecular weight:402.57Rilpivirine
CAS:Controlled Product<p>Applications A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.<br>References Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001),<br></p>Formula:C22H18N6Color and Shape:YellowMolecular weight:366.424-Amino-N-(1,1-dimethylethyl)-4,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide
CAS:Controlled Product<p>Applications 4-Amino-N-(1,1-dimethylethyl)-4,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide is a triazolinone herbicide with a broad spectrum of weed control.<br>References Dayan, F., et al.: Weed Science, 57, 579 (2009); Elmore, M., et al.: Weed Technol., 27, 596 (2013)<br></p>Formula:C10H19N5O2Color and Shape:NeatMolecular weight:241.296,7-DIMETHOXY-2-METHYL-4-(PIPERAZIN-1-YL)QUINAZOLINE
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:288.35101318359375Naloxegol Oxalate
CAS:<p>Applications Naloxegol Oxalate is an oxalate form of Naloxegol (N284470) which is a peripherally-selective opioid antagonist.<br>References Seifert, R., et al.: G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity, 227 (2012)<br></p>Formula:C34H53NO11•C2H2O4Color and Shape:NeatMolecular weight:651.7990033-Phenyl-1-propanol
CAS:Controlled Product<p>Impurity Alverine EP Impurity B<br>Applications 3-Phenyl-1-propanol is used as a reagent in the synthesis of Dihydrocinnamyl Cilnidipine (D448605) and is a potent aroma biotransformation product.<br>References Bosse, A.K., et al.: Food Chem., 141, 2952 (2013)<br></p>Formula:C9H12OColor and Shape:ColourlessMolecular weight:136.19Danofloxacin
CAS:<p>Applications Danofloxacin is a broad spectrum fluoroquinolone antibacterial compound.<br>References Golet, E., et al.: Anal. Chem., 73, 3632 (2001); Golet, E., et al.: Environ. Sci. Technol., 36, 3645 (2002); Huet, A., et al.: J. Agric. Food Chem., 54, 2822 (2006);<br></p>Formula:C19H20FN3O3Color and Shape:Off-WhiteMolecular weight:357.383-Isopropylamino-1,2-propanediol
CAS:<p>Impurity Metoprolol EP Impurity N<br>Applications 3-Isopropylamino-1,2-propanediol (Metoprolol EP Impurity N) is a versatile organic building block, used in different chemical synthesis. It is used in the preparation of heterocyclic propanolamines, which are shown to have β-adrenergic antagonist activity.<br>References Dean, V. et al.: Drug Design and Discovery,10, 89 (1993);<br></p>Formula:C6H15NO2Color and Shape:ColourlessMolecular weight:133.193-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one Hydrochloride
CAS:Controlled Product<p>Impurity Ondansetron EP Impurity A/ Ondansetron USP Related Compound A<br>Applications 3-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one (Ondansetron EP Impurity A) is an impurity of Ondansetron (O655000), an antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackinnon, J.W.M., et al.: Eur. J. Cancer Clin. Oncol., 25, 61 (1989);<br></p>Formula:C16H20N2O·ClHColor and Shape:NeatMolecular weight:292.80KAD-1229 Calcium Hydrate
CAS:Controlled ProductFormula:C19H24NO3·Ca·2H2OColor and Shape:NeatMolecular weight:704.91Cimetidine Sulfoxide
CAS:Controlled Product<p>Impurity Cimetidine EP Impurity E<br>Applications Cimetidine Sulfoxide (Cimetidine EP Impurity E) is a metabolite of the H2-receptor antagonist Cimetidine (C441650). Cimetidine Sulfoxide is detected in the blood and urine of patients with kidney diseases.<br>References Luksa, J. et al.: J. Chrom. B Biomed. Appl., 667, 321 (1995); Lee, R.M. et al.: J. Chrom. Biomed. Appl., 146, 354 (1978);<br></p>Formula:C10H16N6OSColor and Shape:NeatMolecular weight:268.344'-O-Methylcatechin
CAS:<p>Applications A metabolite of (+)-Catechin, a major polyphenol in many fruits and vegetables.<br>References Heptinstall, S., et al.: J. Cardiovas. Pharmacol., 47, S197 (2006), Gonzalez-Manzano, S., et al.: J. Agric. Food Chem., 57, 1231 (2009), Frank, J., et al.: J. Nut., 139, 58 (2009),<br></p>Formula:C16H16O6Color and Shape:NeatMolecular weight:304.29ent-Valsartan
CAS:<p>Impurity Valsartan USP Related Compound A<br>Applications ent-Valsartan (Valsartan USP Related Compound A) is the (R)-enantiomer of Valsartan (V095750).<br>References Corea, L., et al.: Clin. Pharmacol. Ther., 60, 341 (1996), Satana, E;., et al.: J. Pharm. Biomed. Anal., 25, 1009 (2001), Sironi, L., et al.: Hypertension, 37, 961 (2001),<br></p>Formula:C24H29N5O3Color and Shape:WhiteMolecular weight:435.523-Picoline
CAS:Controlled Product<p>Applications A useful precursor to agrochemicals and antidotes for organophosphate poisoning.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Qiao, L., et al.: Bioorg. Med. Chem. Lett., 19, 6122 (2009), Giri, A., et al.: Food Chem., 120, 621 (2010), Farrer, N., et al.: Chem. Res. Toxicol., 23, 413 (2010),<br></p>Formula:C6H7NColor and Shape:ColourlessMolecular weight:93.136,7-Dimethoxyquinazoline-4-one
CAS:<p>Applications Gefitinib intermediate.<br>References Kelly, L., et al.: Cancer Cell., 1, 421 (2002), Pandey, A., et al.: J. Med. Chem., 45, 3772 (2002), Ciardiello, F., et al.: Exp. Opin Emerg. Drugs, 8, 501 (2003), Caponigro, F., et al.: Curr. Opin Oncol., 16, 225 (2004),<br></p>Formula:C10H10N2O3Color and Shape:NeatMolecular weight:206.204-(1-Ethyl-3-methyl-1 H -pyrazol-4-yl)-thiazol-2-ylamine
CAS:Formula:C9H12N4SColor and Shape:SolidMolecular weight:208.28NAP 226-90
CAS:<p>Impurity Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C<br>Applications NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Br. Med. J., 318, 633 (1999), Jann, M., et al.: Clin. Pharmacokinet., 41, 719 (2002), Frankfort, S., et al.: Int. J. Clin. Pract., 60, 646 (2006),<br></p>Formula:C10H15NOColor and Shape:WhiteMolecular weight:165.23N-Methylnitroacetamide
CAS:Controlled Product<p>Impurity Ranitidine EP Impurity H<br>Applications N-Methylnitroacetamide (Ranitidine EP Impurity H) is a degradation product of Ranitidine (R120000).<br>References Sharma, N. et al.: Sci. Pharmac., 79, 309 (2011); Haywood, P.A. et al.: J. Chem. Soc., 5, 951 (1987);<br></p>Formula:C3H6N2O3Color and Shape:NeatMolecular weight:118.094-[2-(4-quinolinyl)vinyl]phenol
CAS:Purity:95.0%Color and Shape:Solid, Yellow powderMolecular weight:247.29699707031255-Chloro-N-cyclohexylpentanamide
CAS:<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>Formula:C11H20ClNOColor and Shape:NeatMolecular weight:217.7364-Amino-2-ethoxy-5-nitro-N-4-piperidinyl-benzamide Hydrobromide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Intermediate in the preparation Cinitapride (C441990).<br></p>Formula:C14H21BrN4O4Color and Shape:NeatMolecular weight:389.24Desmethyl Fondenafil
CAS:<p>Applications Desmethyl Fondenafil is an impurity of the drug Fondenafil/Carbodenafil (F685400) a Sildenafil (S435000) related compound found in health foods.<br>References Hamilton, et al.: J. Med. Chem., 30, 91 (1987),<br></p>Formula:C23H30N6O3Color and Shape:White To Light BeigeMolecular weight:438.52N,N’-Desethylene Ofloxacin Hydrochloride
CAS:Controlled Product<p>Impurity Ofloxacin Desethylene Impurity<br>Applications N,N’-Desethylene Ofloxacin Hydrochloride is an Ofloxacin (O245750) derivative.<br></p>Formula:C16H19ClFN3O4Color and Shape:NeatMolecular weight:371.792-Chloro-5-fluoroquinoline
CAS:Formula:C9H5ClFNPurity:95%Color and Shape:SolidMolecular weight:181.59rac Mepindolol
CAS:Controlled Product<p>Applications Mepindolol is a non-selective β-adrenoceptor blocking agent. Mepindolol is used in the treatment of glaucoma.<br>References Luque Otero, M. et al.: Br. J. Clin. Pharmacol., 17, 361 (1984); Beckmann, R. et al.: Arzneim.-Forsch., 36, 811 (1986);<br></p>Formula:C15H22N2O2Color and Shape:NeatMolecular weight:262.35Marbofloxacin
CAS:<p>Applications Fluorinated quinolone antibacterial.<br>References Gruet, P., et al.: Vet. Rec., 140, 199 (1977), Lefebvre, H.P., et al.: J. Vet. Pharmacol. Ther., 21, 453 (1998),<br></p>Formula:C17H19FN4O4Color and Shape:Off-WhiteMolecular weight:362.36Dimepranol-d6
CAS:Controlled Product<p>Stability Volatile<br>Applications Labelled analiogue of Dimepranol, a component of Inosine pranobex (I822350) that produces a small but significant inhibition of the histamine release from human mast cells. Dimepranol is one of the compounds used to identify the illegal manufacture of methadone.<br>References Gielsdorf, W. et al.: Arch. Kriminol., 164, 83 (1979); Schmutzler, W. et al.: Int. Arch. Allergy Appl. Immunol., 88, 244 (1989);<br></p>Formula:C5H7D6NOColor and Shape:NeatMolecular weight:109.2Vortioxetine Hydrobromide
CAS:<p>Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formula:C18H22N2S·BrHColor and Shape:Beige To Light YellowMolecular weight:379.3584-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-[4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]phenyl]-1-butanone
CAS:<p>Applications 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-[4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]phenyl]-1-butanone is an impurity of Haloperidol (H103700), an antipsychotic agent.<br>References Morris, A.P., et al.: Drug. Meta. Lett., 2, 275 (2008); Morris, A.P., et al.: Int. J. Pharma., 367, 44 (2009);<br></p>Formula:C32H36Cl2N2O3Color and Shape:NeatMolecular weight:567.5510H-Phenothiazine
CAS:Purity:95.0%Color and Shape:Solid, Crystalline Powder or Flakes or Pellets or PowderMolecular weight:199.270004272460946-Methyl-2-pyridin-4-yl-quinoline-4-carboxylic acid
CAS:Purity:90.0%Molecular weight:264.28399658203125[2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone
CAS:<p>Impurity Clozapine EP Impurity D<br>Applications [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone (Clozapine EP Impurity D) is used in the synthesis of substituted dibenzodiazepines. Also an impurity in the synthesis of Clozepine (C587500), an antipsychotic.<br>References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)<br></p>Formula:C18H21ClN4OColor and Shape:Light Red To RedMolecular weight:344.841,3-Adamantanediol
CAS:Controlled Product<p>Applications 1,3-Adamantanediol is used in the synthesis of novel dimethacrylate as possible dental monomers for dental resin mixtures.<br>References Wang, K. et al.: Mat. Sci. Eng. Mat. Biol. Appl., 32, 1141 (2012); Horino, Y. et al.: J. Mol. Catal. A. Chem.,<br></p>Formula:C10H16O2Color and Shape:NeatMolecular weight:168.239,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one (90%)
CAS:Controlled Product<p>Applications Intermediate in the preparation of Ketotifen.<br></p>Formula:C13H10OSPurity:90%Color and Shape:NeatMolecular weight:214.28Dothiepin
CAS:Controlled Product<p>Applications A tricyclic antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metysova, J., et al.: Arzneim.-Forsch., 13, 1039 (1963), Maguire, K.P., et al.: Br. J. Clin. Pharmacol., 12, 405 (1981), Donovan, S., et al.: Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 18, 1143 (1994),<br></p>Formula:C19H21NSColor and Shape:Light Yellow Solid With A Low Melting PointMolecular weight:295.44rac-Hesperetin 7-O-Sulfate Sodium Salt
CAS:<p>Applications rac-Hesperetin 7-O-Sulfate Sodium Salt is a metabolite of rac-Hesperetin (H289501); a derivative of Hesperidine (H281185) with potential antihyperglycemic activity.<br>References Zhang, B., et al.: Bioorg. Med. Chem. Lett., 22, 7194 (2012)<br></p>Formula:C16H13NaO9SColor and Shape:NeatMolecular weight:404.324-(Trifluoromethyl)aniline
CAS:Controlled Product<p>Impurity Leflunomide EP Impurity A; Leflunomide USP Related Compound A<br>Applications 4-(Trifluoromethyl)aniline (Leflunomide EP Impurity A; Leflunomide USP Related Compound A) is a 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weber, W., et al.: Pharmacol. Rev., 37, 25 (1985), Hein, D., et al.: Carcinogenesis, 14, 1633 (1993), Payton, M., et al.: Microbiology, 147, 1137 (2001), Mushtaq, A., et al.: J. Biol. Chem., 277, 12175 (2002),<br></p>Formula:C7H6F3NColor and Shape:NeatMolecular weight:161.12Zileuton
CAS:Controlled Product<p>Applications An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic.<br>References Carter, G.W., et al.: J. Pharmacol. Exp. Ther., 256, 929 (1991), Weinblatt, M.E., et al.: J. Rheumatol., 19, 1537 (1992), McGill, K and Busse, W.W.: Lancet, 348, 519 (1996)<br></p>Formula:C11H12N2O2SColor and Shape:NeatMolecular weight:236.29Ambrisentan Methyl Ester
CAS:Controlled Product<p>Applications (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate is a useful intermediate in the preparation of Ambrisentan. Ambrisentan is an Antihypertensive. Ambrisentan Impurity (A575860).<br>References Peng, X., et al.: J. Org. Chem., 77, 701 (2012), Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003)<br></p>Formula:C23H24N2O4Color and Shape:Off-WhiteMolecular weight:392.45Loratadine N-Oxide
CAS:Controlled Product<p>Applications Loratadine N-oxide nonsedating-type histamine.<br></p>Formula:C22H23ClN2O3Color and Shape:NeatMolecular weight:398.88Dibenzyloxy Tezacaftor-D4
Controlled ProductFormula:C40H35D4F3N2O6Color and Shape:NeatMolecular weight:704.78Vemurafenib
CAS:Controlled Product<p>Applications Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Potent B-Raf inhibitor<br>References Halaban, R. et al.: Pigm. Cell. Melonoma Res., 23, 190 (2010); Yang, H. et al.: Cancer Res., 70, 5518 (2010); Comin-Anduix, B. et al.: Clin. Cancer Res., 16, 6040 (2010);<br></p>Formula:C23H18ClF2N3O3SColor and Shape:NeatMolecular weight:489.92Desfluoro Ezetimibe
CAS:Controlled Product<p>Impurity Ezetimibe Desfluoroaniline Analog (USP)<br>Stability Hygroscopic<br>Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).<br>References Anon.: IP.com J., 7, 4 (2007);<br></p>Formula:C24H22FNO3Color and Shape:White To Off-WhiteMolecular weight:391.43S-Amisulpride
CAS:Controlled Product<p>Applications S-Amisulpride is an isomer of the antipsychotic Amisulpride (A633250). S-Amisulpride has been shown to produce a maximal increase in prolactin level similar to that of the racemic form of Amisulpride.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985); Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997); Marchese, G., et. al.: Eur. J. Pharmacol., 448, 263 (2002)<br></p>Formula:C17H27N3O4SColor and Shape:NeatMolecular weight:369.485-(Imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS:Purity:95.0%Molecular weight:250.26100158691406Ref: 10-F435175
1gTo inquire5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire4'-[(1,7'-Dimethyl-2'-propyl[2,5'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic Acid
CAS:Controlled Product<p>Impurity Telmisartan EP Impurity B; Timolol USP Related Compound B<br>Applications 4’-Desmethyl-7’-methyl Telmisartan (Telmisartan EP Impurity B; Timolol USP Related Compound B) is an impurity of Telmisartan (T017000), an angiotensin II receptor antagonist.<br></p>Formula:C33H30N4O2Color and Shape:Off-WhiteMolecular weight:514.625-(2,6-DIMETHOXYPHENYL)-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID
Purity:90.0%Molecular weight:342.32598876953125Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
CAS:Purity:95.0%Molecular weight:351.4599914550781N”Nitrosoprotriptyline
CAS:Controlled ProductFormula:C19H20N2OColor and Shape:NeatMolecular weight:292.375(E)-Dihydro Efavirenz
CAS:<p>Impurity Efavirenz USP Related Compound B<br>Applications (E)-Dihydro Efavirenz (Efavirenz USP Related Compound B) is an impurity of the nonnucleoside HIV-1 reverse transcriptase inhibitor Efavirenz (E425000).<br>References Weissburg, R.P. et al.: J. Pharmac. Biomed. Anal., 28, 45 (2002); Ribeiro, J.A.A. et al.: J. Pharmac. Biomed. Anal., 43, 298 (2007);<br></p>Formula:C14H11ClF3NO2Color and Shape:NeatMolecular weight:317.69Loxoprofen Ethyl Ester
CAS:Controlled ProductFormula:C17H22O3Color and Shape:NeatMolecular weight:274.355rac threo-Dihydro Bupropion Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications rac threo-Dihydro Bupropion Hydrochloride a metabolite of the drug Bupropion (B689625), a selective inhibitor of dopamine uptake. An antidepressant of the aminoketone class; aid in smoking cessation.<br>References Soroko, F., et al.: J. Pharm. Pharmacol., 29, 769 (1977); Tucker, W.E., J. Clin. Psychiatry, 44, 60 (1983); Hsyu, P-H., et al.: J. Clin. Pharmacol., 37, 737 (1997); West, R., et al.: Expert Opin. Pharmacother., 4, 533 (2003)<br></p>Formula:C13H20ClNO·HClColor and Shape:NeatMolecular weight:241.763646(R)-4-Hydroxy Propranolol Hydrobromide
CAS:Controlled Product<p>Applications The main metabolite of (R)-Propranolol.<br>References Shwed, J., et al.: Xenobiotica, 22, 973 (1992), Fujita, K., et al.: Biol. Pharm. Bull., 22, 446 (1999), Walle, U., et al.: Drug Metab. Dispos., 30, 564 (2002),<br></p>Formula:C16H21NO3·HBrColor and Shape:NeatMolecular weight:356.25N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride
CAS:Controlled Product<p>Applications Hydrochloride Salt of N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester is an intermediate in the preparation of angiotensin II type 1 receptor antagonists.<br>References Goossen, L.J. et al.: J. Org. Chem., 72, 7473 (2007); Nie, Y. et al.: Bioorg. Med. Chem., 20, 2747 (2012);<br></p>Formula:C20H22N2O2·ClHColor and Shape:NeatMolecular weight:358.866-methyl-2-(5-methyl-2-thienyl)quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:283.35000610351563-Chloro-4-nitropyridine N-oxide
CAS:Formula:C5H3ClN2O3Purity:95%Color and Shape:SolidMolecular weight:174.54N-Formyl Linagliptin
Controlled Product<p>Stability Hygroscopic<br>Applications N-Formyl Linagliptin is a derivative of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formula:C26H28N8O3Color and Shape:NeatMolecular weight:500.55α-(4-Chlorophenyl)-2-ethyl-1,3-dioxolane-2-acetonitrile
CAS:Controlled Product<p>Applications α-(4-Chlorophenyl)-2-ethyl-1,3-dioxolane-2-acetonitrile is an impurity of Pyrimethamine (P997240), a dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983); Leport, C., et al.: Am. J. Med., 84, 94 (1988); McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998); Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004);<br></p>Formula:C13H14ClNO2Color and Shape:NeatMolecular weight:251.715-Hydroxy Lansoprazole Potassium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor.<br>References Uno, T., et al.: J. Clin. Pharmacol., 45, 690 (2005), Saito, M., et al.: Brit. J. Clin. Pharmacol., 59, 302 (2005),<br></p>Formula:C16H13F3N3O3S·KColor and Shape:NeatMolecular weight:423.45
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