Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(271 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(98 produtos)
- Lipídio(58 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(165 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8628 produtos de "Metabolismo"
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11-cis Retinol
CAS:<p>11-cisRetinol, a vitamin A isomer, forms from a retinyl ester via RPE65. It's crucial for the visual cycle and cone pigment formation.</p>Fórmula:C20H30OCor e Forma:SolidPeso molecular:286.4591-Deoxysphingosine (m18:1(4E))
CAS:<p>1-Deoxysphingosine, an atypical sphingolipid with a 4E double bond, is linked to increased levels in CIAP and DSPN patients.</p>Fórmula:C18H37NOCor e Forma:SolidPeso molecular:283.5Concizumab
CAS:<p>Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.76 kDaIsariin C
CAS:<p>Isariin C is a flavonoid glucoside derived from the Epimedium plant genus. It stimulates angiogenesis and exhibits antioxidant activity.</p>Fórmula:C28H49N5O7Cor e Forma:SolidPeso molecular:567.72Moth Cytochrome C (MCC) (88-103)
CAS:Moth Cytochrome C (88-103) peptide induces positive TCR selection in thymocytes; key for self-tolerant T cell development.Fórmula:C79H133N23O25Pureza:98%Cor e Forma:SolidPeso molecular:1805.04Mefox
CAS:<p>Mefox is a bioactive chemical.</p>Fórmula:C20H23N7O7Cor e Forma:SolidPeso molecular:473.44Spaglumic acid acetate
Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.Fórmula:C13H20N2O10Pureza:99.49%Cor e Forma:SolidPeso molecular:364.31BMS 195614
CAS:<p>BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.</p>Fórmula:C29H24N2O3Pureza:97.7%Cor e Forma:SolidPeso molecular:448.51Pancreatic lipase-IN-2
Pancreatic lipase-IN-2 (compound 7r) is a potent inhibitor of pancreatic lipase (PL), with an IC50 value of 2.67 μM, and exhibits anti-obesity effects.Fórmula:C32H33N3O2SPeso molecular:523.22935Mannose 6 phosphate
CAS:Mannose 6-phosphate (M6P) features a type I integral membrane receptor.Fórmula:C6H13O9PPeso molecular:260.14Dimethylpropiothetin hydrochloride
CAS:Dimethylpropiothetin hydrochloride (s,s-Dimethyl-β-propionic acid thetine) represents the hydrochloride variant of dimethylpropiothetin. This compound is extractable from marine algae and serves as a precursor to dimethylsulfide (DMS). Additionally, it plays a role in the osmoregulation processes within Hymenomonas carterae.Fórmula:C5H11ClO2SPeso molecular:170.66RORγ allosteric probe-1
CAS:RORγ Allosteric Probe-1 (Compound 12h), with excitation and emission wavelengths of 490/524 nm respectively, serves as an allosteric fluorescent probe for investigating RORγ allosteric inhibitors and the function of RORγ [1].Fórmula:C50H37ClF3N5O11SPeso molecular:1008.37Carboxypeptidase Y, Baker's yeast (S. cerevisiae)
CarboxypeptidaseY, Baker's yeast (S. cerevisiae) serves as a biocatalyst and is a crucial enzyme in advanced biocatalyst technology. Enzyme engineering focuses on improving the kinetics of enzyme reactions, substrate selectivity, and performance under challenging conditions, such as low or high pH. Introducing stimulus-responsive modifications to these enzymes also enables dynamic control of their activity.(±)-Δ7-Mesembrenone
CAS:(±) - Δ 7-Mesembrenone is an alkaloid found in S.tortuosum.Fórmula:C17H21NO3Peso molecular:287.353α,7α-Dihydroxycoprostanic acid
CAS:3α,7α-Dihydroxycoprostanic acid, an endogenous metabolite and bile acid, serves as the precursor to chenodeoxycholic acid [1].Fórmula:C27H46O4Peso molecular:434.65(Z)-7-Dodecen-1-ol
CAS:(Z)-7-Dodecen-1-ol counteracts the attractive properties of Z-7-dodecen-1-yl acetate.Fórmula:C12H24OPeso molecular:184.32Nε,Nε,Nε-Trimethyllysine chloride
CAS:<p>Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine and a component of histone proteins.</p>Fórmula:C9H21ClN2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:224.73RSRGVFF
<p>RSRGVFF (FOXP3 inhibitor P60) is a mixed angiotensin-converting enzyme (ACE) inhibitor with the ability to penetrate the blood-brain barrier, exhibiting an IC50 value of 5.01 μM. It binds to both active and inactive sites of ACE and its substrate HHL complex, thereby reducing the catalytic activity of ACE. RSRGVFF can be further explored for hypertension research.</p>Fórmula:C40H61N13O9Cor e Forma:SolidPeso molecular:867.994CUDA
CAS:<p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>Fórmula:C19H36N2O3Pureza:97.585%Cor e Forma:SolidPeso molecular:340.5Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Fórmula:C77H118N26O25S3Cor e Forma:SolidPeso molecular:1904.11Glucoiberin potassium
CAS:Glucoiberin potassium is an active compound.Fórmula:C11H21KNO10S3Cor e Forma:SolidPeso molecular:462.58Acifluorfen-sodium
CAS:Acifluorfen-sodium is a herbicide.Fórmula:C14H6ClF3NNaO5Cor e Forma:White Crystalline PowderPeso molecular:383.64α-Amylase/α-Glucosidase-IN-17
<p>α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.</p>Fórmula:C19H18FNOCor e Forma:SolidPeso molecular:295.35Cy3-PEG-DSPE (MW 3400)
Cy3-PEG-DSPE (MW 3400) is a PEG phospholipid that incorporates Cy3 dye, utilized for labeling proteins/nucleic acids and in fluorescence microscopy. It can self-assemble in aqueous solutions to form micelles/lipid bilayers, and is employed in the creation of liposomes or nanoparticles for delivering nutrients such as mRNA or DNA vaccines.Cor e Forma:SolidPeso molecular:3400 (Average)Sirtuin modulator 2
CAS:<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>Fórmula:C19H15N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:349.41IGUANA-1
CAS:<p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>Fórmula:C27H26ClN3O4Pureza:99.08%Cor e Forma:SolidPeso molecular:491.97α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid
CAS:<p>α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid was identified as possible dual inhibitors for hLTA4H and hLTC4S enzymes by the computer-aided</p>Fórmula:C23H23NO3Pureza:97.19% - 99.36%Cor e Forma:SoildPeso molecular:361.43LEI110
CAS:<p>LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.</p>Fórmula:C25H23F3N2O3Pureza:98.66% - 98.8%Cor e Forma:SolidPeso molecular:456.46α-Glucosidase-IN-79
<p>α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-glucosidase inhibitor with an IC50 of 2.11 μM, demonstrating greater inhibitory potency than the existing α-glucosidase inhibitors Acarbose (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research in type 2 diabetes.</p>Fórmula:C21H22N2O5SCor e Forma:SolidPeso molecular:414.475Melittin Acetate
<p>Melittin Acetate, a PLA2 activator, enhances low-weight PLA2 activity but not high-weight PLA2.</p>Fórmula:C133H233N39O33Pureza:99.78%Cor e Forma:SoildPeso molecular:2906.51h-NTPDase-IN-1
<p>h-NTPDase-IN-1 (Compound 3i) is an inhibitor of human NTPDase (h-NTPDase) with IC50 values of 2.88 μM for h-NTPDase1 and 0.72 μM for h-NTPDase3, indicating its</p>Fórmula:C17H16BrClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:459.74hCYP3A4-IN-1
<p>hCYP3A4-IN-1 (compound C6) is a potent, orally active inhibitor of hCYP3A4, exhibiting IC50 values of 43.93 nM in human liver microsomes (HLMs) and 153.00 nM in</p>Cor e Forma:Odour Solidα-Glucosidase-IN-41
<p>α-Glucosidase-IN-41 (compound 5o), a potent inhibitor of α-glucosidase, induces alterations in the secondary structure of the enzyme, thereby impeding its</p>Pureza:98%Cor e Forma:Odour Solidω-Conotoxin SO3
CAS:<p>ω-Conotoxin SO3 is an analgesic peptide that functions as an antagonist to N-type voltage-sensitive calcium channels, and can be isolated from the venom of</p>Fórmula:C100H166N36O31S6Pureza:98%Cor e Forma:SolidPeso molecular:2561hCA/VEGFR-2-IN-1
<p>hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (</p>Fórmula:C21H17FN6O3SPureza:98%Cor e Forma:SolidPeso molecular:452.46Acetildenafil
CAS:<p>Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.</p>Fórmula:C25H34N6O3Cor e Forma:Off-White To Pale Yelow SolidPeso molecular:466.58UDP-glucosamine disodium
CAS:<p>UDP-GlcNAc disodium is a substrate for O-GlcNAc transferase and removed by O-GlcNAcase, produced in the hexosamine pathway regulated by GFAT.</p>Fórmula:C15H23N3Na2O16P2Cor e Forma:SolidPeso molecular:609.28Terpendole I
CAS:<p>Terpendole I, from A. yamanashiensis, inhibits ACAT (IC50=145 μM), fights B. cereus/subtilis (MIC=100 μg/ml), and kills HeLa cells (IC50=52.6 μM).</p>Fórmula:C27H35NO5Cor e Forma:SolidPeso molecular:453.579Calcitroic acid
CAS:<p>Calcitroic acid is a vitamin D receptor (VDR) agonist that activates VDR-mediated transcription. It is the primary metabolite of 1,25-dihydroxyvitamin D3, showing the highest concentrations in the liver and mucosa of mice. The compound exhibits metabolic stability and extremely low toxicity.</p>Fórmula:C23H34O4Cor e Forma:SolidPeso molecular:374.514Ledelabricin alfa
<p>Ledelabricin alfa, an isoform A variant of human proteoglycan 4 (PRG4), functions as a lubricant for joints and boundaries.</p>Pureza:98%Cor e Forma:Odour LiquidIHMT-IDH1-053
<p>IHMT-IDH1-053 (compound 16) is an irreversible inhibitor exhibiting high selectivity for the IDH1 R132H mutant, achieving an IC50 of 4.7 nM.</p>Fórmula:C25H33FN6O4SPureza:98%Cor e Forma:SolidPeso molecular:532.63Carbonic anhydrase inhibitor 15
<p>Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].</p>Fórmula:C27H33N5O2S2Pureza:98%Cor e Forma:SolidPeso molecular:523.71Denecimig
CAS:<p>Denecimig (Mim8) is a bispecific and humanized IgG4κ antibody, hemophilia A, activated coagulation factors IXa (FIXa) and X (FX) arresting bleeding.</p>Pureza:95%Cor e Forma:LiquidCA inhibitor 2
<p>Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].</p>Fórmula:C7H9N7O3S3Pureza:98%Cor e Forma:SolidPeso molecular:335.39Valinotricin
CAS:<p>Valinotricin is a minor fungal metabolite.</p>Fórmula:C12H22N2O4Cor e Forma:SolidPeso molecular:258.31Ovalbumin (154-159)
CAS:<p>Ovalbumin (154-159), a peptide fragment derived from ovalbumin, acts as a potent inhibitor of the angiotensin-converting enzyme (ACE) and is utilized in</p>Fórmula:C28H52N10O9Pureza:98%Cor e Forma:SolidPeso molecular:672.77DSPE-PEG2000-CTT2
<p>DSPE-PEG2000-CTT2 is a PEG compound consisting of DSPE and the gelatinase inhibitor CTT2 (CTTHWGFTLC). It possesses the ability to specifically target tumors. DSPE-PEG2000-CTT2 is suitable for drug delivery applications.</p>Cor e Forma:Odour SolidMortatarin F
<p>Mortatarin F (Compound 1), a renyleted flavonoid derived from mulberry leaves, functions as an α-glucosidase inhibitor with an IC50 value of 8.7 μM, making it</p>Fórmula:C25H30O7Pureza:98%Cor e Forma:SolidPeso molecular:442.5α-Amylase/α-Glucosidase-IN-5
<p>α-Amylase/α-Glucosidase-IN-5 (compound 4l) functions as a dual inhibitor, effectively inhibiting both α-glucosidase (Glucosidase) and α-amylase (Amylases) with</p>Fórmula:C30H27BrN3O3PPureza:98%Cor e Forma:SolidPeso molecular:588.43Aculene A
CAS:<p>Aculene A is a unique type of norsesquiterpene from Aspergillus aculeatus [1] .</p>Fórmula:C19H25NO3Cor e Forma:SolidPeso molecular:315.41MAGL-IN-11
<p>MAGL-IN-11 (compound 29) is a selective, reversible inhibitor of monoacylglycerol lipase (MAGL), with potential in researching inflammation, cancer, and</p>Pureza:98%Cor e Forma:Odour SolidFructosyl-lysine dihydrochloride
CAS:<p>Fructoselysine dihydrochloride, a Maillard reaction product and precursor to diabetes marker glucosepane.</p>Fórmula:C12H26Cl2N2O7Cor e Forma:SolidPeso molecular:381.25HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Fórmula:C26H24N6O2Cor e Forma:SolidPeso molecular:452.51IDO1-IN-7
CAS:IDO1-IN-7 is a potent IDO1 inhibitor with a 6.1 nM IC50 and immunomodulatory effects for cancer research.Fórmula:C22H19ClFN3O3Cor e Forma:SolidPeso molecular:427.86α-Glucosidase-IN-25
<p>α-Glucosidase-IN-25 (Compound (R)-8k) serves as a competitive inhibitor for α-glucosidase, demonstrating an inhibitory concentration 50 (IC50) of 1.19μM, making</p>Fórmula:C29H22N6O3Pureza:98%Cor e Forma:SolidPeso molecular:502.52DDC 3′-O-β-D glucuronide
<p>Compound 5, DDC 3′-O-β-D-glucuronide, is a drug metabolite with properties that inhibit the fibrillization and oligomerization of Aβ42, suggesting its potential</p>Pureza:98%Cor e Forma:Odour SolidPDE1-IN-5
<p>PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor with an IC50 of 15 nM, exhibiting anti-inflammatory properties through the inhibition of iNOS, TNF-α, IL</p>Fórmula:C27H29FN4OCor e Forma:SolidPeso molecular:444.54(+)-Geodin
CAS:<p>(+)-Geodin, a fungal metabolite, boosts fibrinolysis in BAECs (50-150 μM) and glucose uptake in rat adipocytes (1-100 μg/ml).</p>Fórmula:C17H12Cl2O7Cor e Forma:SolidPeso molecular:399.18TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Fórmula:C21H18N6O4SCor e Forma:SolidPeso molecular:450.47ω-conotoxin MoVIA
<p>ω-Conotoxin MVIIA is a potent, selective inhibitor of Ca_v2.2, exhibiting an IC_50 of 0.33 μM in the SH-SY5Y fluorimetric hCa_v2.2 assay [1].</p>Fórmula:C147H233N45O47S7Pureza:98%Cor e Forma:SolidPeso molecular:3607.15DSPE-PEG1000-CREKA
<p>DSPE-PEG1000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide has the capability to target tumor cells and tumor vasculature, exhibiting anti-tumor activity. Additionally, DSPE-PEG1000-CREKA can be utilized for drug delivery.</p>Cor e Forma:Odour SolidInostamycin A
CAS:<p>Inostamycin A, a anticancer bacterial metabolite isolated from Streptomyces, is a selective inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase.</p>Fórmula:C38H68O11Cor e Forma:SolidPeso molecular:700.94O-Desmethylcarvedilol
CAS:<p>O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of Carvedilol, a non-selective β-adrenergic receptor (β-AR) antagonist. This compound inhibits store overload-induced calcium release in HEK293 cells expressing the RyR2 R4496C mutation (IC50= 7.62 µM). Additionally, O-Desmethylcarvedilol slows the increase in heart rate and prevents diastolic pressure reduction induced by Isoproterenol in conscious rabbits (ED50s = 32 and 5 µg/kg).</p>Fórmula:C23H24N2O4Cor e Forma:SolidPeso molecular:392.45N-Desmethyl clotiazepam
CAS:<p>N-Desmethyl clotiazepam (Desmethylclotiazepam) is an active metabolite of Clotiazepam.</p>Fórmula:C15H13ClN2OSCor e Forma:SolidPeso molecular:304.8α-Glucosidase-IN-77
<p>α-Glucosidase-IN-77 (Compound H7) is a non-competitive α-glucosidase inhibitor with an IC50 of 1.25 μM. It reduces blood glucose levels, improves glucose tolerance, regulates gut microbiota, and exhibits hepatoprotective effects in a mouse model of type 2 diabetes.</p>Fórmula:C25H16F3NO5SCor e Forma:SolidPeso molecular:499.46Asperaculane B
CAS:<p>Asperaculane B, a fungal metabolite, inhibits P. falciparum (IC50: asexual 3 µM, transmission 7.89 µM) and is non-toxic to human cells.</p>Fórmula:C14H20O3Cor e Forma:SolidPeso molecular:236.31SH7s
<p>SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.</p>Fórmula:C24H19ClF3N5O4SCor e Forma:SolidPeso molecular:565.958-iso Prostaglandin A1
CAS:<p>8-iso PGA1: an isoprostane, non-COX prostanoid, minor PGE1 impurity, biological effects unstudied.</p>Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472DPTIP hydrochloride
CAS:<p>DPTIP hydrochloride is a potent inhibitor of neutral sphingomyelinase (N-SMase 2) that can cross the blood-brain barrier. It acts as an exosome inhibitor with an IC50 value of 30 nM.</p>Fórmula:C21H19ClN2O3SCor e Forma:SolidPeso molecular:414.91Enniatin A
CAS:<p>Enniatin A, a Fusarium toxin, blocks rat liver ACAT with 22 μM IC50.</p>Fórmula:C36H63N3O9Pureza:98%Cor e Forma:SolidPeso molecular:681.9Resinacein L
CAS:<p>Resinacein L is an inhibitor of α-glucosidase with an IC50 of 0.635 mM. This compound can slow the digestion and absorption of carbohydrates, thereby reducing postprandial blood glucose levels.</p>Fórmula:C30H40O8Cor e Forma:SolidPeso molecular:528.6310-Formyldihydrofolate
CAS:<p>10-Formyldihydrofolate is a Methotrexate metabolite. It inhibits thymidylate synthetase and glycinamide ribotide transformylase.</p>Fórmula:C20H21N7O7Cor e Forma:SolidPeso molecular:471.43(S)-O-Desmethyl Venlafaxine N-Oxide
CAS:<p>(S)-O-Desmethyl Venlafaxine N-Oxide is the N-oxide metabolite of Venlafaxine, an SNRI antidepressant.</p>Fórmula:C16H25NO3Cor e Forma:SolidPeso molecular:279.375-Aminolevulinic acid
CAS:<p>5-Aminolevulinic acid: heme synthesis intermediate, photosensitizer, antineoplastic, prodrug, treats actinic keratosis with blue light.</p>Fórmula:C5H9NO3Pureza:98%Cor e Forma:SolidPeso molecular:131.13YYLLVR
CAS:<p>YYLLVR is an inhibitory peptide of angiotensin-converting enzyme (ACE) with an inhibition rate of 89.10%. It demonstrates a low binding energy to ACE at -35.98 kcal/mol. YYLLVR can be utilized in hypertension research.</p>Fórmula:C41H63N9O9Cor e Forma:SolidPeso molecular:825.99Norfenfluramine hydrochloride
CAS:<p>Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, resulting from its N-dealkylation. It serves as a potent anorectic agent and can modulate serotonin neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects following acute administration.</p>Fórmula:C10H13ClF3NCor e Forma:SolidPeso molecular:239.67ChAT IN-1
<p>ChAT IN-1 is a selective inhibitor of Choline Acetyltransferase (ChAT) that is utilized in studying mechanisms related to non-neuronal ChAT overexpression in cancers such as colon cancer and lung cancer, as well as in research concerning Alzheimer's disease (AD).</p>Fórmula:C21H15N3O2Cor e Forma:SolidPeso molecular:341.36tetranor-PGEM
CAS:<p>Tetranor-PGEM, the primary urinary byproduct of PGE1 and PGE2, marks PGE2 production; humans excrete 7-40 μg daily.</p>Fórmula:C16H24O7Cor e Forma:SolidPeso molecular:328.361DSPE-PEG5000-ESBP
<p>DSPE-PEG5000-ESBP is a PEG compound composed of DSPE and E-selectin binding peptide (ESBP). Acting as a tumor-targeting peptide, ESBP has the ability to specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Cor e Forma:Odour SolidDSPE-PEG2000-octreotide
<p>DSPE-PEG2000-Octreotide is a PEG compound composed of DSPE and Octreotide. Octreotide serves as a somatostatin receptor agonist with antitumor properties, mediating apoptosis and applicable in acromegaly research. DSPE-PEG2000-Octreotide is employed in drug delivery systems.</p>Cor e Forma:Odour SolidcMCoFx1
CAS:<p>cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.</p>Fórmula:C146H232N52O44S6Cor e Forma:SolidPeso molecular:3612.12CNBCA
<p>CNBCA, a selective and potent competitive inhibitor of the SHP2 enzyme, exhibits an IC50 value of 0.87 μM.</p>Fórmula:C26H34O5Cor e Forma:SolidPeso molecular:426.55FXR agonist 11
CAS:<p>FXR agonist11 (Compound 14) is an FXR activator with an EC50 of 1.2 μM and a maximal effect of 73.7%. It significantly increases GSH levels in the liver and is used to study drug-induced liver injury.</p>Fórmula:C18H16N2O5Cor e Forma:SolidPeso molecular:340.33LH10
<p>LH10 is an FXR agonist based on fexaramine, with an EC50 of 0.14 μM. It offers hepatoprotective effects, mitigating conditions such as cholestasis induced by alpha naphthylisothiocyanate (ANIT), acute liver injury caused by APAP, and non-alcoholic steatohepatitis (NASH).</p>Fórmula:C34H33N3O2Cor e Forma:SolidPeso molecular:515.64UCM-13207
CAS:UCM-13207 is a specific ICMT inhibitor that improves progeria.Fórmula:C24H32N2O2Pureza:99.83%Cor e Forma:SoildPeso molecular:380.521-Palmitoyl-2-linoleoyl PE
CAS:Phosphatidylethanolamine PLPE: a cell membrane component, studied for anandamide biosynthesis, sPLA2-IIA activity substrate.Fórmula:C39H74NO8PCor e Forma:SolidPeso molecular:715.994SHP2 protein degrader-2
CAS:SHP2 protein degrader-2 (SHP2-D26), a PROTAC degrader targeting the SHP2 protein, effectively diminishes its expression levels across various cancer cell typesFórmula:C56H79ClN12O6S2Cor e Forma:SolidPeso molecular:1115.89Anticancer agent 260
CAS:<p>Anticanceragent 260 (Compound 3g/4d) is an orally effective anticancer agent that inhibits the proliferation of cancer cells HCT-116, MIA-PaCa2, and MDA-MB231, with IC50 values of 98.7, 81.0, and 77.2 µg/mL, respectively. It also promotes ulcer formation and lipid peroxidation, and exhibits anti-inflammatory and analgesic activities.</p>Fórmula:C14H11N3OCor e Forma:SolidPeso molecular:237.265-hydroxy Omeprazole
CAS:<p>5-hydroxy omeprazole, major omeprazole metabolite, formed by CYP2C19, affects gastric H+/K+ pump inhibition.</p>Fórmula:C17H19N3O4SCor e Forma:SolidPeso molecular:361.42TDO-IN-2
<p>TDO-IN-2 is an orally active TDO inhibitor with an IC50 of 1.25 μM. It exhibits antitumor activity in a Hepa1-6 liver cancer allograft mouse model. Additionally, TDO-IN-2 works synergistically with PD-1/PD-L1 inhibitor BMS-202, making it useful for studying tumor immune tolerance.</p>Fórmula:C20H15N3O3Cor e Forma:SolidPeso molecular:345.11134SPL-334
CAS:<p>SPL-334 is an inhibitor of S-nitrosoglutathione reductase.</p>Fórmula:C22H15N3O3S2Pureza:98%Cor e Forma:SolidPeso molecular:433.50b-Cortolone
CAS:<p>b-Cortolone, a metabolite of Cortisol, exhibits relatively lower biological activity.</p>Fórmula:C21H34O5Cor e Forma:SolidPeso molecular:366.49Creatine riboside
CAS:<p>Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.</p>Fórmula:C9H17N3O6Pureza:98%Cor e Forma:SolidPeso molecular:263.2511-Hydroxy cannabinol
CAS:<p>11-Hydroxy cannabinol (Compound 5b) is an active metabolite of cannabinol.</p>Fórmula:C21H26O3Cor e Forma:SolidPeso molecular:326.43DSPE-PEG2000-CGKRK
<p>DSPE-PEG2000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is suitable for use in drug delivery.</p>Cor e Forma:Odour SolidAPP-018
CAS:<p>APP-018 (D-4F) is an 18 D-amino acid peptide that mimics apolipoprotein A-I (apoA-I). It enhances the anti-inflammatory properties of high-density lipoprotein (HDL) and is applicable in cardiovascular disease research.</p>Fórmula:C114H156N24O28Cor e Forma:SolidPeso molecular:2310.6N-Desmethyl Bendamustine
CAS:<p>N-DesmethylBendamustine is a metabolite of Bendamustine. It exerts cytotoxic effects on various lymphoma cell lines and peripheral blood lymphocytes.</p>Fórmula:C15H19Cl2N3O2Cor e Forma:SolidPeso molecular:344.242-Methylnicotinamide
CAS:<p>2-Methylnicotinamide is an endogenous metabolite of nicotinamide and can be used for related research in the life sciences.</p>Fórmula:C7H8N2OPureza:99.84%Cor e Forma:SolidPeso molecular:136.15DPPD-Q
CAS:<p>DPPD-Q, an antioxidant and an oxidative derivative of substituted p-phenylenediamine (DPPD), is identified in tire wear particles, rubber debris, particulate matter 2.5 (PM2.5), and wastewater influents and effluents. At a concentration of 5 µM, DPPD-Q inhibits soybean urease by 91.4%.</p>Fórmula:C18H14N2O2Cor e Forma:SolidPeso molecular:290.32Antibacterial agent 132
CAS:<p>Antibacterial agent 132 showed antimicrobial activity against C.</p>Fórmula:C24H17ClN4OSPureza:98%Cor e Forma:SolidPeso molecular:444.94
