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Metabolismo

Metabolismo

Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.

Subcategorias de "Metabolismo"

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Foram encontrados 9054 produtos de "Metabolismo"

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  • Creatine-d3

    CAS:
    Creatine-d3 is an isotopically labeled version of creatine. Creatine is an endogenous amino acid metabolite that plays a crucial role in cellular energy, particularly within muscles and the brain.
    Fórmula:C4H9N3O2
    Cor e Forma:Solid
    Peso molecular:134.15
  • 21-Deoxy Cortisone

    CAS:
    <p>21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.</p>
    Fórmula:C21H28O4
    Cor e Forma:Solid
    Peso molecular:344.44
  • 514O6,10

    CAS:
    514O6,10 functions as an ionizable cationic lipid utilized in creating lipid nanoparticles (LNPs) for in vivo mRNA delivery. In mice, LNPs incorporating 514O6,10 and containing an mRNA reporter primarily target the spleen, lungs, and liver.
    Fórmula:C87H172N4O8
    Peso molecular:1402.32
  • N-Lactylvaline

    CAS:
    N-Lactylvaline is an endogenous metabolite detectable in patients with intermediate maple syrup urine disease.
    Fórmula:C8H15NO4
    Cor e Forma:Solid
    Peso molecular:189.21
  • BuChE-IN-15


    BuChE-IN-15, a chemical compound, exhibits potent inhibitory activity with IC50 values of 81 nM and 400 nM, respectively. It also demonstrates good blood-brain barrier permeability and neuroprotective properties, making it suitable for research in Alzheimer's disease.
    Fórmula:C18H18FNO4
    Cor e Forma:Solid
    Peso molecular:331.34
  • WVSAV


    <p>WVSAV is a ligand for the PDZ2 domain (tyrosine phosphatase) with a dissociation constant (Kd) of 111 μM. It is utilized in studies of protein-ligand interactions.</p>
    Fórmula:C27H40N6O7
    Cor e Forma:Solid
    Peso molecular:560.64
  • 1,2-bis(heptanoylthio) Glycerophosphocholine

    CAS:
    Diheptanoyl Thio-PC, a PLA2s substrate, doesn't work with cPLA2/PAF-AH. Interacts with PLA2, sn-2 cleavage produces free thiol, detected using DTNB/DTP.
    Fórmula:C22H44NO6PS2
    Cor e Forma:Solid
    Peso molecular:513.69
  • Cucumarioside H

    CAS:
    Cucumarioside H is a triterpene glycoside
    Fórmula:C60H92O29S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1309.43
  • AV22-149


    AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .
    Fórmula:C23H28F3N3O6S2
    Cor e Forma:Solid
    Peso molecular:563.61
  • ST8 α-2,8-Sialyltransferase 4


    ST8 alpha-2,8-Sialyltransferase 4 (ST8SIA4) is a sialyltransferase enzyme involved in the sialylation process. It is also associated with breast cancer progression, facilitating cancer cell proliferation and invasion in a sialyltransferase-dependent manner.
  • RMC-4630

    CAS:
    <p>RMC-4630 (SHP2-IN-7) is an inhibitor of SHP2.</p>
    Fórmula:C20H27ClN6O2S
    Pureza:99.07% - 99.65%
    Cor e Forma:Solid
    Peso molecular:450.99
  • 4-Nitrophenyl Phenylphosphonate

    CAS:
    4-Nitrophenyl phenylphosphonate: stable, easy-to-make 5'-nucleotide phosphodiesterase substrate; hydrolyzes faster than natural options.
    Fórmula:C12H10NO5P
    Cor e Forma:Solid
    Peso molecular:279.19
  • L 645164

    CAS:
    L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.
    Fórmula:C22H23FO3
    Cor e Forma:Solid
    Peso molecular:354.41
  • Acetaminophen Glucuronide sodium salt

    CAS:
    Acetaminophen Glucuronide sodium salt (APAP-glu) is a compound with antipyretic and analgesic activity and potential nephrotoxicity.
    Fórmula:C14H16NNaO8
    Cor e Forma:Off-White Cyrstalline Solid
    Peso molecular:349.27
  • FTI-2148 diTFA

    CAS:
    FTI-2148 diTFA inhibits FT-1 and GGT-1 with IC50s of 1.4 nM and 1.7 μM; a RAS-mimetic compound.
    Fórmula:C26H29F3N4O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:566.6
  • Leucomyosuppressin

    CAS:
    Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
    Fórmula:C59H84N16O15
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1257.418
  • Lentztrehalose A

    CAS:
    Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase—an enzyme involved in trehalose metabolism—more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and >20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enhances survival rates and impedes tumor growth in a Sarcoma 180 murine sarcoma model.
    Fórmula:C17H32O13
    Cor e Forma:Solid
    Peso molecular:444.43
  • 3-Hydroxyanisole

    CAS:
    3-Hydroxyanisole has inhibitory activity against MAO-A (IC50 = 24 ± 2.8 μM) and can be used to study neurological and psychiatric diseases.
    Fórmula:C7H8O2
    Pureza:98.96%
    Cor e Forma:Clear Pink To Red Liquid With The Odor Of Phenol And Carmel
    Peso molecular:124.14
  • 6-O-Demethyl Griseofulvin

    CAS:
    6-O-demethyl Griseofulvin is a metabolite of the antifungal griseofulvin .1,2
    Fórmula:C16H15ClO6
    Cor e Forma:Solid
    Peso molecular:338.74
  • Bam 12P acetate


    <p>Bam 12P acetate is the putative enkephalin precursor in bovine adrenal, pituitary, and hypothalamus.</p>
    Fórmula:C64H101N21O18S
    Pureza:98.84%
    Cor e Forma:Solid
    Peso molecular:1484.68