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Metabolismo

Metabolismo

Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.

Subcategorias de "Metabolismo"

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Foram encontrados 8628 produtos de "Metabolismo"

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  • Logotipo do CymitQuimica
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    Galactose 1-dehydrogenase

    <p>Galactose 1-dehydrogenase, pseudomonas fluorescens, a dehydrogenase found in Pseudomonas fluorescens, facilitates the oxidation of L-arabinose and D-galactose, utilizing NADP+/NAD+ as a cofactor. This enzyme is employed in diagnostic assays to quantify total galactose levels and serves as a biocatalyst in the production of galacturonic acid salts.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T200393

  • 4-Hydroxyphenylbutazone
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    4-Hydroxyphenylbutazone

    CAS:
    <p>4-Hydroxyphenylbutazone, a Phenylbutazone metabolite, enhances PHS's peroxidase activity as an NSAID.</p>
    Fórmula:C19H20N2O3
    Cor e Forma:Solid
    Peso molecular:324.38

    Ref: TM-T39152

  • DHODH-IN-23
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    DHODH-IN-23

    CAS:
    <p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>
    Fórmula:C24H21ClFNO4
    Pureza:99.7%
    Cor e Forma:Solid
    Peso molecular:441.88

    Ref: TM-T67875

  • ESI1
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    ESI1

    <p>ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.</p>
    Fórmula:C18H18ClN5O
    Cor e Forma:Solid
    Peso molecular:355.82

    Ref: TM-T200212

  • Trifluoperazine N-Glucuronide
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    Trifluoperazine N-Glucuronide

    CAS:
    <p>Trifluoperazine N-Glucuronide is a metabolite of Trifluoperazine with antidepressant and antipsychotic activity.</p>
    Fórmula:C27H32F3N3O6S
    Cor e Forma:Solid
    Peso molecular:583.62

    Ref: TM-T29009

  • Mebeverine acid
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    Mebeverine acid

    CAS:
    <p>Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.</p>
    Fórmula:C16H25NO3
    Pureza:99.66%
    Cor e Forma:Solid
    Peso molecular:279.37

    Ref: TM-T11986

  • Toddacoumalone
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    Toddacoumalone

    CAS:
    <p>Toddacoumalone, a natural PDE4 inhibitor, shows promise for inflammatory disease research.</p>
    Fórmula:C31H31NO6
    Cor e Forma:Solid
    Peso molecular:513.58

    Ref: TM-T75486

  • Diphlorethohydroxycarmalol
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    Diphlorethohydroxycarmalol

    CAS:
    <p>Diphlorethohydroxycarmalol is a useful organic compound for research related to life sciences and the catalog number is T125953.</p>
    Fórmula:C24H16O13
    Cor e Forma:Solid
    Peso molecular:512.379

    Ref: TM-T125953

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    Glycerol-3-phosphate dehydrogenase

    CAS:
    <p>Glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is an enzyme that catalyzes the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP), playing a crucial role in glycerol metabolism and energy production. This enzyme acts as the rate-limiting step in glycerol production within Saccharomyces cerevisiae, regulating glycerol formation and accumulation to aid the yeast in adapting to hyperosmotic environments. Additionally, glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is relevant in research within the field of metabolic engineering.</p>
    Cor e Forma:Solid

    Ref: TM-T89979

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    Maurocalcine TFA

    <p>Maurocalcine TFA acts as an agonist for ryanodine receptor (RyR) channels 1, 2, and 3, demonstrating cell-penetrating capabilities. It induces binding of [3H]ryanodine to RyR1 with an EC50 of 2558 nM and exhibits an apparent affinity of 14 nM for RyR2. This compound is applicable for in vivo cell tracking or other cellular imaging techniques.</p>
    Fórmula:C156H270N56O46S6·xC2HF3O2
    Cor e Forma:Solid
    Peso molecular:3858.55 (free base)

    Ref: TM-TP2868

  • (S)-3,4-Dihydroxybutyric acid
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    (S)-3,4-Dihydroxybutyric acid

    CAS:
    (S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.
    Fórmula:C4H8O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:120.1

    Ref: TM-T13978

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    Epoxide hydrolase

    CAS:
    <p>Epoxide hydrolase, an enzyme responsible for catalyzing the reaction of epoxides with water to convert epoxy groups into diols, plays a crucial role in the metabolism of environmental pollutants and lipids. It is instrumental in detoxification, inflammatory responses, and regulating the health of the cardiovascular system. Additionally, Epoxide hydrolase is used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, which are important for the synthesis of chiral pharmaceutical molecules.</p>
    Cor e Forma:Solid

    Ref: TM-T200049

  • CP-610431
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    CP-610431

    CAS:
    <p>CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.</p>
    Fórmula:C30H37N3O2
    Cor e Forma:Solid
    Peso molecular:471.645

    Ref: TM-T40675

  • 2-Hydroxyquinoline
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    2-Hydroxyquinoline

    CAS:
    <p>Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Fórmula:C9H7NO
    Cor e Forma:White Solid
    Peso molecular:145.15

    Ref: TM-PDK0291

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    THX6

    <p>THX6 is an activator of human mitochondrial protease ClpP, with an EC50 of 1.18 μM. It displays cytotoxicity in ONC201-resistant SU-DIPG-VI cells, with an IC50 of 0.13 μM. THX6 inhibits the expression of mitochondria-related proteins (such as parkin, TFAM, NRF1, SDHA), leading to impaired mitochondrial function. Additionally, THX6 affects cell membrane lipid metabolism and exhibits antitumor potential.</p>
    Fórmula:C22H18Cl2N4O2
    Cor e Forma:Solid
    Peso molecular:441.31

    Ref: TM-T205692

  • Hydroxycotinine
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    Hydroxycotinine

    CAS:
    <p>Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.</p>
    Fórmula:C10H12N2O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:192.218

    Ref: TM-T19361

  • Seco Rapamycin sodium salt
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    Seco Rapamycin sodium salt

    CAS:
    <p>Seco Rapamycin sodium salt is a ring-opened product of Rapamycin.</p>
    Fórmula:C51H79NNaO13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:937.177

    Ref: TM-T19558

  • 7-Hydroxymethotrexate
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    7-Hydroxymethotrexate

    CAS:
    7-Hydroxymethotrexate, major Methotrexate metabolite, inhibits dihydrofolate reductase and DNA synthesis by blocking folic acid conversion.
    Fórmula:C20H22N8O6
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:470.44

    Ref: TM-T20339

  • Logotipo do CymitQuimica
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    DSPE-PEG5000-YIGSR

    <p>DSPE-PEG5000-YIGSR is a PEG compound comprised of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, such as endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG5000-YIGSR is applicable for drug delivery.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01115

  • 8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside
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    8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside

    CAS:
    <p>8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside (Compound 3), a natural product isolated from Bidens bipinnata, exhibits a 22% inhibition against α-amylase at</p>
    Fórmula:C21H20O11
    Cor e Forma:Solid
    Peso molecular:448.38

    Ref: TM-T75701