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Metabolismo

Metabolismo

Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.

Subcategorias de "Metabolismo"

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Foram encontrados 8628 produtos de "Metabolismo"

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  • PFKFB3-IN-2
    Targetmol
    + Info

    PFKFB3-IN-2

    CAS:
    PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor.
    Fórmula:C14H11NO7S
    Pureza:99.15%
    Cor e Forma:Solid
    Peso molecular:337.3

    Ref: TM-T67874

  • ISM012-042
    Targetmol
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    ISM012-042

    <p>ISM012-042 is an orally active inhibitor of PHD1 and PHD2, with IC50 values of 1.9 and 2.5 nM, respectively. At a concentration of 2.5 μM, ISM012-042 protects Caco-2 cells from DSS-induced barrier damage. Additionally, in LPS-induced bone marrow-derived dendritic cells (BMDC) from mice, ISM012-042 exhibits anti-inflammatory properties by dose-dependently reducing the expression of IL-12 subunit IL-12p35 and TNF. It also restores intestinal barrier function and alleviates intestinal inflammation in various experimental colitis models. ISM012-042 is useful for studying intestinal mucosal repair and immune disorders.</p>
    Fórmula:C26H28N6O4
    Cor e Forma:Solid
    Peso molecular:488.538

    Ref: TM-T204762

  • Methiocarb
    Targetmol
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    Methiocarb

    CAS:
    Methiocarb is a carbamate insecticide acting as a reversible AChE or ChE inhibitor, inducing oxidative stress in rats.
    Fórmula:C11H15NO2S
    Pureza:98.49%
    Cor e Forma:Colorless Crystals Immobilizing Agent For Birds Acaricide And Molluscicide (Epa 1998)
    Peso molecular:225.31

    Ref: TM-T21464

  • CA IX/VEGFR-2-IN-3
    Targetmol
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    CA IX/VEGFR-2-IN-3

    <p>CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.</p>
    Fórmula:C19H16ClN3O5S2
    Cor e Forma:Solid
    Peso molecular:465.93

    Ref: TM-T204735

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    ω-Conotoxin FVIA

    <p>ω-Conotoxin FVIA is an inhibitor of N-type Ca²⁺ channels (Caᵥ2.2), shown to alleviate mechanical and thermal pain abnormalities in a rat model of caudal nerve</p>
    Fórmula:C98H164N36O33S6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2566.96

    Ref: TM-T80446

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Cy3-PEG-DSPE (MW 5000)

    <p>Cy3-PEG-DSPE (MW 5000) is a fluorescent PEG phospholipid that incorporates Cy3 dye and is utilized for protein/nucleic acid labeling. It can self-assemble into micelles or lipid bilayers in aqueous solutions and is employed in the preparation of liposomes or nanoparticles for the delivery of substances such as mRNA or DNA vaccines.</p>
    Cor e Forma:Solid
    Peso molecular:5000 (Average)

    Ref: TM-T204790

  • LEI110
    Targetmol
    + Info

    LEI110

    CAS:
    <p>LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.</p>
    Fórmula:C25H23F3N2O3
    Pureza:98.66% - 98.8%
    Cor e Forma:Solid
    Peso molecular:456.46

    Ref: TM-T9753

  • LDHA-IN-8
    Targetmol
    + Info

    LDHA-IN-8

    CAS:
    <p>LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.</p>
    Fórmula:C15H14N4O2
    Pureza:99.73%
    Cor e Forma:Solid
    Peso molecular:282.3

    Ref: TM-T200300

  • (±)-threo-3-Methylglutamic acid
    Targetmol
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    (±)-threo-3-Methylglutamic acid

    CAS:
    <p>glutamate transport blocker</p>
    Fórmula:C6H11NO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:161.16

    Ref: TM-T22485

  • Fumarate hydratase-IN-2 sodium salt
    Targetmol
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    Fumarate hydratase-IN-2 sodium salt

    CAS:
    <p>Fumarate hydratase-IN-2 Na salt: cell-permeable, competitive inhibitor (Ki=4.5μM), nutrient-dependent cytotoxicity.</p>
    Fórmula:C25H25N2NaO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:440.47

    Ref: TM-T11336

  • α-Glucosidase-IN-84
    Targetmol
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    α-Glucosidase-IN-84

    <p>α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.</p>
    Fórmula:C25H29N7O3S
    Cor e Forma:Solid
    Peso molecular:507.608

    Ref: TM-T205575

  • Calcium Channel antagonist 3
    Targetmol
    + Info

    Calcium Channel antagonist 3

    CAS:
    <p>Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>
    Fórmula:C23H26N2O4S
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:426.53

    Ref: TM-T77712

  • SW209049
    Targetmol
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    SW209049

    CAS:
    <p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>
    Fórmula:C25H18N2O4S
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:442.49

    Ref: TM-T9859

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    α-Glucosidase-IN-36

    <p>α-Glucosidase-IN-36 (compound 5g) is a potent inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and inhibition constants Ki and Kis of 1.65</p>
    Fórmula:C26H24BrN5O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:566.47

    Ref: TM-T78881

  • Dimethylaminomicheliolide HCl
    Targetmol
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    Dimethylaminomicheliolide HCl

    CAS:
    <p>Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate</p>
    Fórmula:C17H28ClNO3
    Pureza:99.55%
    Cor e Forma:Soild
    Peso molecular:329.86

    Ref: TM-T60102L

  • Penicillide
    Targetmol
    + Info

    Penicillide

    CAS:
    <p>Penicillide: fungal metabolite, inhibits calpain 2/ACAT (IC50 = 7.1/22.9 μM), blocks oxytocin receptors (IC50 = 67 μM), stops RNA synthesis in P388 cells.</p>
    Fórmula:C21H24O6
    Cor e Forma:Solid
    Peso molecular:372.417

    Ref: TM-T36931

  • L-Isoleucyl-L-arginine
    Targetmol
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    L-Isoleucyl-L-arginine

    CAS:
    <p>L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in</p>
    Fórmula:C12H25N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:287.36

    Ref: TM-T80096

  • 11β-HSD1 inibitor 17
    Targetmol
    + Info

    11β-HSD1 inibitor 17

    CAS:
    <p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>
    Fórmula:C22H20F3N3O2S
    Pureza:99.26% - 99.72%
    Cor e Forma:Soild
    Peso molecular:447.47

    Ref: TM-T67903

  • MK-4074
    Targetmol
    + Info

    MK-4074

    CAS:
    <p>MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).</p>
    Fórmula:C33H31N3O6
    Cor e Forma:Solid
    Peso molecular:565.62

    Ref: TM-T12062

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    PTPσ Inhibitor, ISP

    <p>PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling.</p>
    Fórmula:C177H306N66O54S3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4318.93

    Ref: TM-T80544