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Metabolismo

Metabolismo

Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.

Subcategorias de "Metabolismo"

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Foram encontrados 8626 produtos de "Metabolismo"

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  • Logotipo do CymitQuimica
    Targetmol
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    Octocog alfa

    CAS:
    <p>Octocog alfa, a second-generation, full-length recombinant antihemophilic factor VIII (AHF), is utilized for the treatment of Hemophilia A [1].</p>
    Cor e Forma:Solid

    Ref: TM-T81622

  • MK-8262
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    MK-8262

    CAS:
    <p>MK-8262: oral CETP inhibitor, potent (IC50 = 53 nM, log D = 5.3), may impact HDL/LDL and CHD research.</p>
    Fórmula:C35H25F9N2O5
    Cor e Forma:Solid
    Peso molecular:724.58

    Ref: TM-T38908

  • Logotipo do CymitQuimica
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    Lipoxygenase

    CAS:
    <p>Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.</p>
    Cor e Forma:Solid

    Ref: TM-T76164

  • Caffeoylcalleryanin
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    Caffeoylcalleryanin

    CAS:
    <p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>
    Fórmula:C22H24O11
    Cor e Forma:Solid
    Peso molecular:464.4

    Ref: TM-TN7391

  • Teprotide
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    Teprotide

    CAS:
    <p>Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].</p>
    Fórmula:C53H76N14O12
    Cor e Forma:Solid
    Peso molecular:1101.26

    Ref: TM-TP2636

  • PROTAC CYP1B1 degrader-2
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    PROTAC CYP1B1 degrader-2

    CAS:
    <p>PROTAC CYP1B1 degrader-2 (compound PV2), a VHL (von Hippel - Landau) E3 ligase-based degrader of CYP1B1, exhibits a DC50 of 1.0 nM after 24 hours in A549/Taxol cells. Furthermore, it effectively inhibits the growth, migration, and invasion of A549/Taxol cells.</p>
    Fórmula:C49H56ClN7O5S3
    Cor e Forma:Solid
    Peso molecular:954.66

    Ref: TM-T88545

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    BAY-277

    <p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>
    Fórmula:C44H52N8O5
    Cor e Forma:Solid
    Peso molecular:772.93

    Ref: TM-T205262

  • Logotipo do CymitQuimica
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    FABP4-IN-4

    <p>FABP4-IN-4 (Compound 30) is an orally effective inhibitor of FABP, with an IC50 value of 1.18 μM against FABP1. In a mouse model of diet-induced obesity, FABP4-IN-4 improves glucose tolerance, reduces levels of blood sugar, lipids, and liver inflammation markers, alleviates hepatic steatosis, and exhibits anti-inflammatory activity.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T89572

  • Logotipo do CymitQuimica
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    α-Amylase-IN-11

    <p>α-Amylase-IN-11 (compound C5f) is an α-amylase inhibitor with an IC50 of 0.56 μM, effective in reducing glucose levels in vivo. Additionally, it exhibits moderate inhibitory activity against α-glucosidase with an IC50 of 11.03 μM. In mouse models, α-Amylase-IN-11 significantly decreases glucose concentrations, indicating its potential for diabetes research.</p>
    Fórmula:C22H18N4OS
    Cor e Forma:Solid
    Peso molecular:386.47

    Ref: TM-T205363

  • 11β-HSD1 inibitor 19
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    11β-HSD1 inibitor 19

    CAS:
    <p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>
    Fórmula:C19H16ClF4N3O2S
    Pureza:99.58%
    Cor e Forma:Soild
    Peso molecular:461.86

    Ref: TM-T72022

  • N,S-Bis-Fmoc-Glutathione
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    N,S-Bis-Fmoc-Glutathione

    CAS:
    <p>N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a K i of 0.32 mM [1].</p>
    Fórmula:C40H37N3O10S
    Cor e Forma:Solid
    Peso molecular:751.8

    Ref: TM-T80098

  • Methionylserine
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    Methionylserine

    CAS:
    <p>Methionylserine (H-MET-SER-OH), a dipeptide, binds hPEPT1 (Km 0.2 mM), inhibits ACE, used in hypertension research.</p>
    Fórmula:C8H16N2O4S
    Cor e Forma:Solid
    Peso molecular:236.29

    Ref: TM-T77199

  • KT-362 free base
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    KT-362 free base

    CAS:
    <p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>
    Fórmula:C22H28N2O3S
    Pureza:99.76%
    Cor e Forma:Soild
    Peso molecular:400.53

    Ref: TM-T73587

  • 11β-HSD1 inibitor 17
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    11β-HSD1 inibitor 17

    CAS:
    <p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>
    Fórmula:C22H20F3N3O2S
    Pureza:99.26% - 99.72%
    Cor e Forma:Soild
    Peso molecular:447.47

    Ref: TM-T67903

  • Dimethylaminomicheliolide HCl
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    Dimethylaminomicheliolide HCl

    CAS:
    <p>Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate</p>
    Fórmula:C17H28ClNO3
    Pureza:99.55%
    Cor e Forma:Soild
    Peso molecular:329.86

    Ref: TM-T60102L

  • CUDA
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    CUDA

    CAS:
    <p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>
    Fórmula:C19H36N2O3
    Pureza:97.585%
    Cor e Forma:Solid
    Peso molecular:340.5

    Ref: TM-T10900

  • N-Fmoc-D-glutamine
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    N-Fmoc-D-glutamine

    CAS:
    <p>N-Fmoc-D-glutamine is Fmoc-protected alpha-glutamine. Alpha-glutamine is an α-amino acid and the most abundant free amino acid in human blood.</p>
    Fórmula:C20H20N2O5
    Pureza:99.14%
    Peso molecular:368.38

    Ref: TM-TP3278

  • SY-640
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    SY-640

    CAS:
    <p>SY-640, an acetamide derivative, strongly protects the liver and lessens Propionibacterium acnes and lipopolysaccharide-induced damage in mice.</p>
    Fórmula:C11H13NO3
    Pureza:99.51% - 99.66%
    Cor e Forma:Solid
    Peso molecular:207.23

    Ref: TM-T37859

  • Sirtuin modulator 2
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    Sirtuin modulator 2

    CAS:
    <p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>
    Fórmula:C19H15N3O2S
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:349.41

    Ref: TM-T9999

  • Ercalcitriol
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    Ercalcitriol

    CAS:
    <p>Ercalcitriol, active Vitamin D2 metabolite, boosts immunity by regulating CAMP and DEFB4 genes against infections.</p>
    Fórmula:C28H44O3
    Pureza:99.02%
    Cor e Forma:Solid
    Peso molecular:428.65

    Ref: TM-TQ0216