Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(165 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8597 produtos de "Metabolismo"
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ICMT-IN-6
CAS:<p>ICMT-IN-6 (compound 29) serves as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an inhibitory concentration 50 (IC50) value of</p>Fórmula:C23H31NO2Cor e Forma:SolidPeso molecular:353.5AR453588
CAS:<p>AR453588 is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>Fórmula:C25H25N7O2S2Cor e Forma:SolidPeso molecular:519.64Diethyl-pythiDC
CAS:<p>Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.</p>Fórmula:C14H14N2O4SPureza:99.98%Cor e Forma:SolidPeso molecular:306.34LX-1031
CAS:<p>LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.</p>Fórmula:C28H25F3N4O4Pureza:97.123% - 98.97%Cor e Forma:SolidPeso molecular:538.52IDH1 Inhibitor 3
CAS:<p>IDH1 Inhibitor 3 is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor (IC50: 45 nM for IDH1R132H).</p>Fórmula:C31H25F4N5O3Pureza:98%Cor e Forma:SolidPeso molecular:591.56sEH/AChE-IN-3
CAS:<p>sEH/AChE-IN-3 -15: potent dual sEH & AChE inhibitor; crosses BBB; IC50: hsEH 0.4nM, hAChE 1.94nM, hBChE 615nM, msEH 4.3nM, mAChE 2.61nM.</p>Fórmula:C35H39ClF3N5O3Cor e Forma:SolidPeso molecular:670.16PPARγ agonist 8
CAS:<p>PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferator</p>Fórmula:C19H12F4O2SPureza:98%Cor e Forma:SolidPeso molecular:380.36CMI-392
CAS:<p>CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).</p>Fórmula:C31H37ClN2O8SPureza:98%Cor e Forma:SolidPeso molecular:633.15Glucocerebrosidase-IN-1 hydrochloride
CAS:<p>Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent, selective GCase (glucocerebrosidase) inhibitor with IC50 and Ki values of 29.3 μM and 18.5 μM</p>Fórmula:C13H28ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:281.82PF-04937319
CAS:<p>PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.</p>Fórmula:C22H20N6O4Pureza:99.89%Cor e Forma:SolidPeso molecular:432.43S-(p-Nitrobenzyl)glutathione
CAS:<p>S-(p-Nitrobenzyl)glutathione acts as a competitive inhibitor of glutathionase.</p>Fórmula:C17H22N4O8SCor e Forma:SolidPeso molecular:442.44AZD-6605
CAS:<p>AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.</p>Fórmula:C18H21F4N3O6SCor e Forma:SolidPeso molecular:483.431,2-Dimyristoyl-3-palmitoyl-rac-glycerol
CAS:<p>1,2-Dimyristoyl-3-palmitoyl-rac-glycerol (MMP) is a triacylglycerol comprising myristic acid and palmitic acid [1].</p>Fórmula:C47H90O6Cor e Forma:SolidPeso molecular:751.21C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0)
CAS:<p>C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is a lipid molecule that can be used in life science related research. The CAS number of C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is 34249-41-7.</p>Fórmula:C36H71NO4Cor e Forma:SolidPeso molecular:581.967PDE5-IN-42
CAS:<p>PDE5-IN-42 is a selective inhibitor of second-generation phosphodiesterase type 5 (PDE5).</p>Fórmula:C23H31N7O3Pureza:98%Cor e Forma:SolidPeso molecular:453.541-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium
CAS:<p>1-Oleoyl-2-hydroxy-sn-glycero-3-PG (sodium salt), a lysophospholipid with oleic acid (18:1) at the sn-1 position, finds application in creating micelles, liposomes, and various artificial membranes, notably in lipid-based drug delivery systems.</p>Fórmula:C24H46NaO9PCor e Forma:SolidPeso molecular:532.587ICMT-IN-28
CAS:<p>ICMT-IN-28 (compound 65) serves as an inhibitor of ICMT, exhibiting significant potency with an IC50 value of 0.008 μM [1].</p>Fórmula:C22H28FNO2Cor e Forma:SolidPeso molecular:357.46SR11237
CAS:<p>SR11237 is a Pan retinoid X receptor (RXR) agonist.</p>Fórmula:C24H28O4Pureza:98.79%Cor e Forma:SolidPeso molecular:380.48Quetiapine sulfoxide hydrochloride
<p>Quetiapine sulfoxide hydrochloride is a main metabolite of Quetiapinem. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.</p>Fórmula:C21H26ClN3O3SPureza:98%Cor e Forma:SolidPeso molecular:435.97Cholesterol 24-hydroxylase-IN-2
CAS:<p>Cholesterol 24-hydroxylase-IN-2 is a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), exhibiting an IC50 value of 5.4 nM, and has potential</p>Fórmula:C20H23FN4OCor e Forma:SolidPeso molecular:354.42ICMT-IN-14
CAS:<p>ICMT-IN-14 (compound 50) serves as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting potent activity with an IC50 of 0.025 μM [1].</p>Fórmula:C21H25ClFNOCor e Forma:SolidPeso molecular:361.88GSK-8062
CAS:<p>GSK-8062 is an agonist of farnesoid X receptor (FXR).</p>Fórmula:C30H23Cl2NO4Pureza:98%Cor e Forma:SolidPeso molecular:532.41FXIa-IN-1
CAS:<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Fórmula:C20H19F3N4O5Pureza:98%Cor e Forma:SolidPeso molecular:452.38GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Fórmula:C21H24F3N7OPureza:99.86% - 99.86%Cor e Forma:SolidPeso molecular:447.46Autotaxin-IN-4
CAS:<p>Autotaxin-IN-4 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.</p>Fórmula:C22H21N9O2Pureza:98%Cor e Forma:SolidPeso molecular:443.4614,15-Epoxyeicosatrienoic acid
CAS:<p>14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.47Glycosidase-IN-2
CAS:<p>Glycosidase-IN-2 is a glycosidase inhibitor with hypoglycemic activity.</p>Fórmula:C13H23NO5Pureza:98%Cor e Forma:SolidPeso molecular:273.331-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol
CAS:<p>1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol, a triacylglycerol, features myristic acid, linoleic acid, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. This compound is prevalent in mature human milk, infant formula fats, and butterfat.</p>Fórmula:C53H96O6Cor e Forma:SolidPeso molecular:829.33IDH889
CAS:<p>IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).</p>Fórmula:C23H25FN6O2Pureza:≥98%Cor e Forma:SolidPeso molecular:436.48XR3054
CAS:<p>XR3054 is a farnesyl protein transferase inhibitor that blocks proliferation in certain cancer cells, not dependent on ras mutation status.</p>Fórmula:C13H22O2Cor e Forma:SolidPeso molecular:210.31JNJ-40929837
CAS:<p>JNJ-40929837 is an oral inhibitor of LTA4 hydrolase, which catalyzes LTB4 production.</p>Fórmula:C22H24N4O2SCor e Forma:SolidPeso molecular:408.521,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE
CAS:<p>1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.</p>Fórmula:C39H78NO8PCor e Forma:SolidPeso molecular:720.026(±)-HIP-A
CAS:<p>(±)-HIP-A is an excitatory amino acid transporter blocker.</p>Fórmula:C6H8N2O4Pureza:98%Cor e Forma:SolidPeso molecular:172.14SHP2-IN-21
CAS:<p>SHP2-IN-21 (compound 208) is an inhibitor of SHP2, exhibiting an IC50 of 3 nM, and is utilized in glioblastoma research [1].</p>Fórmula:C27H26FN7Cor e Forma:SolidPeso molecular:467.54BI-11634
CAS:<p>BI-11634 is a factor Xa inhibitor.</p>Fórmula:C22H23ClN4NaO4Pureza:98%Cor e Forma:SolidPeso molecular:465.891,2-Distearoyl-3-Oleoyl-rac-glycerol
CAS:<p>1,2-Distearoyl-3-oleoyl-rac-glycerol, a triacylglycerol, comprises stearic acid at the sn-1 and sn-2 positions and oleic acid at the sn-3 position. This compound is present in cocoa butter and vegetable oils.</p>Fórmula:C57H108O6Cor e Forma:SolidPeso molecular:889.46FR-186054
CAS:<p>FR-186054, a potent ACAT inhibitor with high oral efficacy, outperforms others in vitro regardless of dosage.</p>Fórmula:C26H27N5OS2Pureza:98%Cor e Forma:SolidPeso molecular:489.66(S)-(-)-Bay-K-8644
CAS:<p>(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.</p>Fórmula:C16H15F3N2O4Pureza:98.28% - 99.37%Cor e Forma:SolidPeso molecular:356.3DNCA
CAS:<p>DNCA, a neutral lipid, facilitates the creation of lipid nanoparticles (LNPs) and is instrumental in [nucleic acid delivery](1).</p>Fórmula:C45H82N4O4Cor e Forma:SolidPeso molecular:743.16ICMT-IN-31
CAS:<p>ICMT-IN-31 (compound 68) serves as an ICMT inhibitor, demonstrating significant potency with an IC50 value of 0.0038 μM [1].</p>Fórmula:C19H24ClNOSCor e Forma:SolidPeso molecular:349.921-Palmitoyl-2-Oleoyl-3-Stearoyl-rac-glycerol
CAS:<p>1-Palmitoyl-2-oleoyl-3-stearoyl-rac-glycerol, a primary triacylglycerol in cocoa butter, features palmitic acid (at the sn-1 position), oleic acid (at the sn-2 position), and stearic acid (at the sn-3 position).</p>Fórmula:C55H104O6Cor e Forma:SolidPeso molecular:861.41SHP2-IN-18
CAS:<p>SHP2-IN-18 (compound 183) is a potent SHP2 inhibitor, exhibiting an IC50 of 3 nM and applicable to glioblastoma research [1].</p>Fórmula:C26H27FN6Cor e Forma:SolidPeso molecular:442.53JTV-803 mesylate
CAS:<p>JTV-803 inhibits factor Xa (K(i) 0.019 µM, IC(50) 0.081 µM), 100x more selective vs thrombin, extends clotting times dose-dependently.</p>Fórmula:C23H31N5O6SPureza:98%Cor e Forma:SolidPeso molecular:505.59cis-13-Octadecenoic Acid
CAS:<p>Cis-13-Octadecenoic acid, a monounsaturated fatty acid, is identified in bovine milk fat.</p>Fórmula:C18H34O2Cor e Forma:SolidPeso molecular:282.46ATX inhibitor 21
CAS:<p>ATX inhibitor 21 is a potent inhibitor of ATX (IC50: 3490 nM).</p>Fórmula:C26H25F2N5O2SCor e Forma:SolidPeso molecular:509.57S-Fcme
CAS:<p>S-Fcme activates multidrug resistance transporter by boosting ATPase activity and competing for drug binding.</p>Fórmula:C19H33NO2SCor e Forma:SolidPeso molecular:339.54S-Benzylglutathione
CAS:<p>S-Benzylglutathione acts as a competitive inhibitor of glutathionase and undergoes conversion by rat kidney microsomes into its cysteine derivatives.</p>Fórmula:C17H23N3O6SCor e Forma:SolidPeso molecular:397.45Prostaglandin F2α-1-glyceryl ester
CAS:<p>Prostaglandin F2α-1-glyceryl ester undergoes oxidation via 15-hydroxyprostaglandin dehydrogenase (15-HPGDH) [1].</p>Fórmula:C23H40O7Cor e Forma:SolidPeso molecular:428.566KD-026
CAS:<p>KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.</p>Fórmula:C31H25F3N2O4Pureza:99.74%Cor e Forma:SolidPeso molecular:546.54Quetiapine sulfoxide dihydrochloride
CAS:<p>Quetiapine sulfoxide dihydrochloride, a major metabolite of second-gen antipsychotic Quetiapine, modulates 5-HT and dopamine receptors.</p>Fórmula:C21H27Cl2N3O3SPureza:98%Cor e Forma:SolidPeso molecular:472.43Tisolagiline
CAS:<p>Tisolagiline (KDS2010) is a potent, highly selective and reversible MAO-B inhibitor oral activity for the treatment of Alzheimer's disease and obesity.</p>Fórmula:C17H17F3N2OPureza:99.65%Cor e Forma:SolidPeso molecular:322.33Quercetin 7-glucuronide
CAS:<p>Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL</p>Fórmula:C21H18O13Pureza:98%Cor e Forma:SolidPeso molecular:478.363-Oxo-5β-cholanoic acid
CAS:<p>3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation of TH17 cells by directly</p>Fórmula:C24H38O3Pureza:98.01% - 99.86%Cor e Forma:SolidPeso molecular:374.56DORI
CAS:<p>DORI, a cationic lipid, efficiently delivers plasmid DNA in vitro, exhibiting lower cytotoxicity and high transfection efficiency [1].</p>Fórmula:C43H82BrNO5Cor e Forma:SolidPeso molecular:773.02AR453588 hydrochloride
CAS:<p>AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>Fórmula:C25H26ClN7O2S2Pureza:98%Cor e Forma:SolidPeso molecular:556.1N-Palmitoyl Taurine
CAS:<p>N-Palmitoyl taurine, an amino-acyl endocannabinoid prominent in rat brain lipidomics profiling, accompanies multiple arachidonoyl amino acids isolated from bovine brain, including N-arachidonoylethanolamine (NADA) and N-arachidonoyl serine (ARA-S). Mass spectral lipidomic analysis of rat brain additionally revealed a series of fatty acyl amides with taurine. The function of N-Palmitoyl taurine is under investigation.</p>Fórmula:C18H37NO4SCor e Forma:SolidPeso molecular:363.6MMV009085
CAS:<p>MMV009085 is a potent inhibitor of the Plasmodium falciparum hexose transporter (Pf HT1), with potential as an anti-malarial agent.</p>Fórmula:C22H22N2O6Cor e Forma:SolidPeso molecular:410.42CM-10-18
CAS:<p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>Fórmula:C17H35NO5Cor e Forma:SolidPeso molecular:333.46MK-8189
CAS:<p>MK-8189 is a potent and selective pyrimidine PDE10A inhibitor, with excellent PDE (phosphodiesterase) selectivity for the treatment of schizophrenia.</p>Fórmula:C19H22N6OSPureza:99.38% - 99.67%Cor e Forma:SolidPeso molecular:382.48Glycosidase-IN-1
CAS:<p>Glycosidase-IN-1, a D-mannose-derived inhibitor, has hypoglycemic effects and aids in creating immunosuppressants and β-glucosidase blockers.</p>Fórmula:C13H23NO5Pureza:98%Cor e Forma:SolidPeso molecular:273.33FASN-IN-1
CAS:<p>FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme</p>Fórmula:C18H25N3O3S2Pureza:99.92% - >99.99%Cor e Forma:SolidPeso molecular:395.54h-NTPDase-IN-5
CAS:<p>h-NTPDase-IN-5 (compound 3b) serves as a pan-inhibitor of NTPDase, exhibiting inhibitory concentration 50 (IC50) values of 1.10 μM (h-NTPDase1), 44.73 μM (h-</p>Fórmula:C23H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:403.5SHP2-IN-19
CAS:<p>SHP2-IN-19 (compound 183) is a SHP2 inhibitor exhibiting potent activity with an IC50 of 3 nM, and is utilized in glioblastoma research [1].</p>Fórmula:C27H28N6O2Cor e Forma:SolidPeso molecular:468.55RORγt Inverse agonist 6
CAS:<p>RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.</p>Fórmula:C28H29ClN6O5Pureza:99.52%Cor e Forma:SolidPeso molecular:565.02MSI-1436
CAS:<p>MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)</p>Fórmula:C37H72N4O5SPureza:98%Cor e Forma:SolidPeso molecular:685.06Lateritin
CAS:<p>Lateritin (Bassiatin) is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor from the mycelial cake of Gibberella</p>Fórmula:C15H19NO3Pureza:99.23%Cor e Forma:SolidPeso molecular:261.32UK 357903
CAS:<p>UK 357903, a phosphodiesterase 5A (PDE5A) inhibitor, is used potentially for the treatment of erectile dysfunction.</p>Fórmula:C27H34N8O5SCor e Forma:SolidPeso molecular:582.67hMAO-B-IN-32
CAS:<p>hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.</p>Fórmula:C16H19NO4Pureza:99.65%Cor e Forma:SolidPeso molecular:289.335(S)-HETrE
CAS:<p>5(S)-HETrE, made by 5-LO from mead acid, has unknown biological activity and metabolic fate.</p>Fórmula:C20H34O3Cor e Forma:SolidPeso molecular:322.484′-DTMP
CAS:<p>4′-DTMP (4-Demethyltrimethoprim) is a DHFR inhibitor with antimicrobial activity against Escherichia coli.</p>Fórmula:C13H16N4O3Pureza:98%Cor e Forma:SolidPeso molecular:276.29DGAT1-IN-1
CAS:<p>DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).</p>Fórmula:C30H28F3N3O4Pureza:99.14%Cor e Forma:SolidPeso molecular:551.56Efipladib
CAS:<p>Efipladib is a phospholipase inhibitor. Efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid.</p>Fórmula:C40H35Cl3N2O4SCor e Forma:SolidPeso molecular:746.14Me-Indoxam
CAS:<p>Me-Indoxam is an inhibitor of sPLA2. It has no effect on arachidonic acid release and platelet activating factor synthesis.</p>Fórmula:C26H22N2O5Pureza:98%Cor e Forma:SolidPeso molecular:442.46Prostaglandin B2
CAS:<p>Prostaglandin B2 is a dehydration product of PGE2/PGA2 with weak TP receptor activity, raising rabbit pulmonary pressure at >5 ug/kg.</p>Fórmula:C20H30O4Cor e Forma:SolidPeso molecular:334.45FXIa-IN-7
CAS:<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Fórmula:C28H28N2O4Pureza:98.55%Cor e Forma:SolidPeso molecular:456.53NC1
CAS:<p>NC1 is a potent allosteric inhibitor of lymphoid-specific PTPN22, a protein tyrosine phosphatase.</p>Fórmula:C29H26N2O7SCor e Forma:SolidPeso molecular:546.59PDE5-IN-2
CAS:<p>PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)</p>Fórmula:C25H21N3O6SPureza:98%Cor e Forma:SolidPeso molecular:491.52GLX481304
CAS:<p>GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.</p>Fórmula:C23H29N7OCor e Forma:SolidPeso molecular:419.52BBT
CAS:<p>BBT has anti-hyperglycemic activity, protecting beta cells from cytokine or streptozotocin-induced cell death, and restoring beta cell function.</p>Fórmula:C18H12BrNO2SPureza:99.02%Cor e Forma:SolidPeso molecular:386.26TMP780
CAS:<p>TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders.</p>Fórmula:C31H30N2O4Pureza:98%Cor e Forma:SolidPeso molecular:494.58C82
CAS:<p>C82 acts as an inhibitor of Mycobacterium tuberculosis (Mtb) cyclic dinucleotide phosphodiesterase (CdnP), with an IC50 value of 17.5 µM. This particular enzyme is responsible for breaking down cyclic di-AMP (c-di-AMP) into adenosine 5'-monophosphate (AMP). Notably, C82 demonstrates selectivity for Mtb CdnP over other bacterial cyclic dinucleotide phosphodiesterases (CDN PDEs) such as Yybt, RocR, and Group B Streptococcus (GBS) CdnP, as well as the mammalian CDN PDE ENPP1, and the viral CDN PDE poxin, showing effectiveness at a concentration of 200 µM.</p>Fórmula:C17H17N3O3SCor e Forma:SolidPeso molecular:343.4JP104
CAS:<p>JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].</p>Fórmula:C25H30N2O3Pureza:98%Cor e Forma:SolidPeso molecular:406.52Temocaprilat
CAS:<p>Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor.</p>Fórmula:C21H24N2O5S2Pureza:99.31%Cor e Forma:White To Off-White SolidPeso molecular:448.56Iganidipine
CAS:<p>Iganidipine（NKY 722） is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.</p>Fórmula:C28H38N4O6Pureza:96.3%Cor e Forma:SolidPeso molecular:526.62NOX2-IN-2
CAS:<p>NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.</p>Fórmula:C25H25N7O3Cor e Forma:SolidPeso molecular:471.51HSD17B13-IN-3
CAS:<p>HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].</p>Fórmula:C22H21NO6S2Cor e Forma:SolidPeso molecular:459.541-Deazaadenosine
CAS:<p>1-Deazaadenosine, an adenosine deaminase inhibitor (Ki: 0.66 μM), may treat cancer, particularly lymphoproliferative disorders.</p>Fórmula:C11H14N4O4Pureza:98%Cor e Forma:SolidPeso molecular:266.254-Methylumbelliferyl-α-D-Glucopyranoside
CAS:<p>4-Methylumbelliferyl-α-D-Glucopyranoside (4MU-αGlc) is a fluorescence substrate for α-glucosidase, serving as a biomarker for Fabry disease and Pompe disease</p>Fórmula:C16H18O8Pureza:99.97%Cor e Forma:SolidPeso molecular:338.31ICMT-IN-19
CAS:<p>ICMT-IN-19 (compound 53) serves as a potent inhibitor of ICMT, demonstrating an IC50 value of 0.026 μM [1].</p>Fórmula:C21H26N2O3Cor e Forma:SolidPeso molecular:354.44DPM-1001
CAS:<p>DPM-1001 is an orally bioavailable and non-competitive protein-tyrosine phosphatase (PTP1B) inhibitor (IC50: 100 nM) with the anti-diabetic property.</p>Fórmula:C35H57N3O3Pureza:98%Cor e Forma:SolidPeso molecular:567.85TMDJ-035
CAS:<p>TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2).</p>Fórmula:C16H12F3N5OPureza:98%Cor e Forma:SolidPeso molecular:347.29hCAIX-IN-15
CAS:<p>hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer</p>Fórmula:C18H14FN7O2SPureza:98%Cor e Forma:SolidPeso molecular:411.41α-Glucosidase-IN-28
CAS:<p>α-Glucosidase-IN-28 (Compound 18) is an α-glucosidase inhibitor with an IC50 of 0.62 μM and Ki value of 3.93 μM.</p>Fórmula:C29H22Br2O7Pureza:98%Cor e Forma:SolidPeso molecular:642.293,5-Dinitrocatechol
CAS:<p>OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.</p>Fórmula:C6H4N2O6Pureza:99.8%Cor e Forma:SolidPeso molecular:200.11hCAIX/XII-IN-8
CAS:<p>hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.</p>Fórmula:C16H13Cl2N5O3SPureza:98%Cor e Forma:SolidPeso molecular:426.28R1498
CAS:<p>R1498 inhibits CDK2, targets angiogenesis and mitosis, and is an oral treatment for liver and stomach cancer.</p>Fórmula:C18H15ClN4OPureza:98%Cor e Forma:SolidPeso molecular:338.79Cav 3.2 inhibitor 4
CAS:<p>Cav 3.2 Inhibitor 4 (Compound 21) is a selective and potent inhibitor of the T-type calcium channel (Ca v 3.2), demonstrating peripheral restriction with an</p>Fórmula:C21H32Cl2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:459.41RORγt inverse agonist 14
CAS:<p>RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an EC50 of 2.5 nM, exhibiting anti-inflammatory activity.</p>Fórmula:C26H26F8N2O6S2Pureza:98%Cor e Forma:SolidPeso molecular:678.61GGTI-2133
CAS:<p>GGTI-2133: potent GGTase I inhibitor, IC50=38 nM; blocks inflammatory cell invasion in mice asthma.</p>Fórmula:C27H28N4O3Pureza:99.75%Cor e Forma:SolidPeso molecular:456.54PDP-EA
CAS:<p>PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.</p>Fórmula:C25H43NO3Pureza:99.59%Cor e Forma:SolidPeso molecular:405.61Tetramyristoylcardiolipin
CAS:<p>Tetramyristoylcardiolipin (TMCL), an anionic lipid, plays a crucial role in studying cell membrane function and drug delivery mechanisms [1].</p>Fórmula:C65H132N2O17P2Cor e Forma:SolidPeso molecular:1275.69FXa-IN-1
CAS:<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Fórmula:C24H18F5N5OCor e Forma:SolidPeso molecular:487.42LNP Lipid-8
CAS:<p>LNP Lipid-8 (11-A-M), an ionizable lipid, is utilized in lipid nanoparticles (LNP) for siRNA delivery to T cells without ligand targeting. When loaded with GFP siRNA (siGFP), it significantly silences the GFP gene in a mouse model [1].</p>Fórmula:C42H71NO7Cor e Forma:SolidPeso molecular:702.02AMC Arachidonoyl Amide
CAS:<p>Arachidonoyl amide (AMC-AA) is a fatty acid amide among several that serve to quantify fatty acid amide hydrolase (FAAH) activity. FAAH, with its relative lack of selectivity, processes various amide head groups beyond ethanolamine, the head group of its primary endogenous substrate, anandamide (AEA). The interaction of AMC-AA with FAAH leads to the liberation of fluorescent aminomethyl coumarin, which has an absorption peak at 360 nm and emission at 465 nm. This fluorescence release facilitates the rapid and efficient assessment of FAAH activity through the utilization of either a standard cuvette or a microplate fluorometer.</p>Fórmula:C30H39NO3Cor e Forma:SolidPeso molecular:461.6LY-338979
CAS:<p>LY-338979 is an impurity of pemetrexedone.</p>Fórmula:C20H21N5O7Pureza:98%Cor e Forma:SolidPeso molecular:443.41DHODH-IN-22
CAS:<p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>Fórmula:C21H21ClF4N6O5Cor e Forma:SolidPeso molecular:548.88Glyoxalase I inhibitor 3
CAS:<p>Compound 22g: potent GLO1 inhibitor; IC50=0.011 μM; potential for depression, anxiety research.</p>Fórmula:C22H21N3O3Cor e Forma:SolidPeso molecular:375.42ICMT-IN-54
CAS:<p>ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated by</p>Fórmula:C29H45NO3SCor e Forma:SolidPeso molecular:487.74(Rac)-Lonafarnib
CAS:<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Fórmula:C27H31Br2ClN4O2Cor e Forma:SolidPeso molecular:638.82Sampatrilat
CAS:<p>Sampatrilat, an oral vasopeptidase inhibitor, more potently blocks C-domain ACE (Ki=13.8 nM) over N-domain (Ki=171.9 nM).</p>Fórmula:C26H40N4O9SPureza:98%Cor e Forma:SolidPeso molecular:584.68α-Glucosidase-IN-11
CAS:<p>α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM).</p>Fórmula:C23H20N2O6Cor e Forma:SolidPeso molecular:420.4117(S)-HpDHA
CAS:<p>17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].</p>Fórmula:C22H32O4Cor e Forma:SolidPeso molecular:360.49DOG-IM4
CAS:<p>DOG-IM4 is a chemical compound instrumental in synthesizing nanoparticles for delivering antigen-encoding nucleic acids, targeting a broad range of conditions including autoimmune diseases, rare blood or metabolic disorders, allergies, cancer, and infectious diseases [1].</p>Fórmula:C51H95N3O7Cor e Forma:SolidPeso molecular:862.32FR-190809
CAS:<p>FR-190809 is a nonadrenotoxic and orally efficacious inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) (IC50: 45 nM).</p>Fórmula:C29H34FN3O6S2Pureza:98%Cor e Forma:SolidPeso molecular:603.73Lp-PLA2-IN-14
CAS:<p>Lp-PLA2-IN-14 (Compound 19), an inhibitor of rhLp-PLA2, exhibits a potent inhibitory effect with a pIC50 value of 8.4.</p>Fórmula:C16H14F3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:353.3Bemfivastatin hemicalcium
CAS:<p>Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.</p>Fórmula:C34H36FN2O6CaCor e Forma:SolidPeso molecular:607.67QH536
CAS:<p>QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.</p>Fórmula:C33H49N3O3Cor e Forma:SolidPeso molecular:535.76MAGL-IN-6
CAS:<p>MAGL-IN-6, a powerful MAGL blocker, IC50 at 4.71 nM, may assist in neurological disease research.</p>Fórmula:C24H19F3N4OCor e Forma:SolidPeso molecular:436.43Aladotrilat
CAS:<p>Aladotrilat is an inhibitor of neutral endopeptidase. Its prodrug is aladrotril.</p>Fórmula:C14H17NO5SCor e Forma:SolidPeso molecular:311.35ICMT-IN-21
CAS:<p>ICMT-IN-21 (compound 6ag) is an ICMT inhibitor with an IC50 value of 8.8 µM, featuring sulfonamide-modified farnesyl cysteine (SMFC).</p>Fórmula:C22H33NO4S3Cor e Forma:SolidPeso molecular:471.7Biliverdin
CAS:<p>Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].</p>Fórmula:C33H34N4O6Cor e Forma:SolidPeso molecular:582.65Tiracizine HCl
CAS:<p>Tiracizine HCl, a new class I antiarrhythmic drug, was studied in patients with ischemic heart disease and shown to decrease myocardial contractile function.</p>Fórmula:C21H26ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:403.9N-type calcium channel blocker-1
CAS:<p>N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.</p>Fórmula:C31H47N3Pureza:98%Cor e Forma:SolidPeso molecular:461.73(R)-IDO/TDO-IN-1
CAS:<p>(R)-IDO/TDO-IN-1 (compound 25), an indoleamine-2,3-dioxygenase (IDO) inhibitor, demonstrates good pharmacokinetic properties and exerts anti-tumor effects in the MC38 xenograft model. This compound exhibits synergy when combined with the anti-PD-1 monoclonal antibody (SHR-1210) [1].</p>Fórmula:C25H24FN5Cor e Forma:SolidPeso molecular:413.49M5N36
CAS:<p>M5N36: selective Cdc25C inhibitor, IC50: 0.15µM A, 0.19µM B, 0.06µM C; halts cell growth, boosts p-CDK1/2.</p>Fórmula:C20H16ClN5O3Cor e Forma:SolidPeso molecular:409.83AalphaC
CAS:<p>AalphaC (2-Amino-alpha-carboline) is a potential carcinogen.</p>Fórmula:C11H9N3Pureza:99.32%Cor e Forma:Crystalline SolidPeso molecular:183.218(Z)-Eicosenoic Acid
CAS:<p>8(Z)-Eicosenoic acid, a cis-unsaturated free fatty acid featuring a 20-carbon chain, enhances acetylcholine (ACh) receptor channel currents without causing depression and augments PCKε phosphorylation of a substrate peptide in Xenopus oocytes. This acid comprises 6% of the fatty acid composition in seed oil extracted from B. collina.</p>Fórmula:C20H38O2Cor e Forma:SolidPeso molecular:310.522C24:1 dihydro 1-Deoxyceramide (m18:0/24:1)
CAS:<p>C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) is 1246298-60-1.</p>Fórmula:C42H83NO2Cor e Forma:SolidPeso molecular:634.11Safinamide Acid
CAS:<p>Safinamide acid, a potential impurity in commercial safinamide preparations and a degradation product of safinamide under thermal and oxidative stress, is encountered in the pharmaceutical formulation process.</p>Fórmula:C17H18FNO3Cor e Forma:SolidPeso molecular:303.33SREBP/SCAP-IN-1
CAS:<p>SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].</p>Fórmula:C28H40F2N4OCor e Forma:SolidPeso molecular:486.64IDO-IN-9
CAS:<p>IDO-IN-9 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.011 μM (Kinase) and 0.0018 μM (Hela Cell).</p>Fórmula:C13H13BrFN7O3SPureza:98%Cor e Forma:SolidPeso molecular:446.25cis-8-Octadecenoic Acid
CAS:<p>Cis-8-Octadecenoic acid, a monounsaturated fatty acid and isomer of oleic acid, trans-vaccenic acid, trans-petroselinic acid, and cis-petroselinic acid, is present in partially hydrogenated vegetable oil and milk fat.</p>Fórmula:C18H34O2Cor e Forma:SolidPeso molecular:282.46Arachidonoyl-N-methyl amide
CAS:<p>Anandamide (AEA), an endogenous cannabinoid, interacts with both central (CB1) and peripheral (CB2) cannabinoid receptors. Its effects are concluded through the cellular uptake and enzymatic breakdown of its amide bond by fatty acid amide hydrolase. Arachidonoyl-N-methyl amide, an analog of anandamide, specifically targets the human CB1 receptor, displaying a binding affinity with a Ki of 60 nM. It completely inhibits rat glial gap junction intercellular communication at a concentration of 50 µM.</p>Fórmula:C21H35NOCor e Forma:SolidPeso molecular:317.5Hypogeic acid
CAS:<p>Hypogeic acid is isolable from cultures of autotrophic bacteria linked to sulfate accumulation in biofilters [1].</p>Fórmula:C16H30O2Cor e Forma:SolidPeso molecular:254.4112(R)-HEPE
CAS:<p>12(R)-HEPE, a monohydroxy fatty acid derived from EPA in the eggs of the sea urchin S. purpuratus, has a biological activity that, while not extensively documented, may resemble that of 12(R)-HETE (Catalog No.34560).</p>Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.5ICMT-IN-27
CAS:<p>ICMT-IN-27, also known as compound 64, is an inhibitor of the enzyme ICMT, demonstrating potent activity with an IC50 value of 0.1 µM [1].</p>Fórmula:C22H28FNO2Cor e Forma:SolidPeso molecular:357.46Oxalomalic acid trisodium
CAS:<p>Oxalomalic acid (Oxalomalate) trisodium, an inhibitor of aconitase and NADP-dependent isocitrate dehydrogenase, suppresses nitrite production and inducible nitric oxide synthase (iNOS) protein expression in lipopolysaccharide-activated J774 macrophages [1].</p>Fórmula:C6H3Na3O8Cor e Forma:SolidPeso molecular:272.05GNE-6468
CAS:<p>GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).</p>Fórmula:C23H16ClN3O4Cor e Forma:SolidPeso molecular:433.84SCD1/5-IN-1
CAS:<p>SCD1/5-IN-1 (Compound 10), a selective SCD1/5 inhibitor, is utilized in the research of neurological diseases [1].</p>Fórmula:C12H10N4O3Cor e Forma:SolidPeso molecular:258.237MGAT2-IN-2
CAS:<p>MGAT2-IN-2 is a potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) (IC50 of 3.4 nM).</p>Fórmula:C26H21F5N4O4SPureza:98%Cor e Forma:SolidPeso molecular:580.53ICMT-IN-45
CAS:<p>ICMT-IN-45 (compound 24) serves as an ICMT inhibitor, demonstrating an IC50 value of 0.132 μM [1].</p>Fórmula:C24H33NOCor e Forma:SolidPeso molecular:351.52L-CCG-lll
CAS:<p>inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate.</p>Fórmula:C6H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:159.14Cholesterylamine
CAS:<p>Cholesterylamine, a cationic lipid, can be incorporated into PLGA to create particles with a charged surface, facilitating its use in drug delivery systems and</p>Fórmula:C27H47NCor e Forma:SolidPeso molecular:385.675-PAHSA
CAS:<p>5-PAHSA, a FAHFA formed through the formal condensation of the carboxy group of palmitic acid with the hydroxy group of 5-hydroxystearic acid, serves as a human metabolite, possesses anti-inflammatory and hypoglycemic properties, and is categorized as a long-chain fatty acid. This compound, deriving from hexadecanoic acid and octadecanoic acid, is the conjugate acid of a 5-PAHSA(1-).</p>Fórmula:C34H66O4Cor e Forma:SolidPeso molecular:538.898ICMT-IN-41
CAS:<p>ICMT-IN-41 (compound 20) serves as a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.069 μM [1].</p>Fórmula:C23H31NOCor e Forma:SolidPeso molecular:337.5CHK-336
CAS:<p>CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria</p>Fórmula:C24H20F2N4O4S2Cor e Forma:SolidPeso molecular:530.57FAAH inhibitor 2
CAS:<p>FAAH Inhibitor 2 (Compound 17b) is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 value of 0.153 μM [1].</p>Fórmula:C24H40N2O2Cor e Forma:SolidPeso molecular:388.59Curcumin-β-D-glucuronide
CAS:<p>Curcumin-β-D-glucuronide, a principal metabolite detected in hepatic tissue and portal blood following oral consumption of Curcumin, is utilized in colon cancer</p>Fórmula:C27H28O12Pureza:98%Cor e Forma:SolidPeso molecular:544.5ICMT-IN-32
CAS:<p>ICMT-IN-32 (compound 70) acts as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.777 µM [1].</p>Fórmula:C20H25NO2Cor e Forma:SolidPeso molecular:311.42Lipid AX4
CAS:<p>"Lipid AX4, characterized as an ionizable cationic lipid with a pKa of 6.89, facilitates the formation of lipid nanoparticles (LNPs) for in vivo mRNA delivery [1]."</p>Fórmula:C83H155N3O16Cor e Forma:SolidPeso molecular:1451.13IDH1 Inhibitor 5
CAS:<p>IDH1 Inhibitor 5 targets MOG cells (IC50: 64.4 nM) and R132H mutant IDH1 gliomas (IC50: 34.9 nM).</p>Fórmula:C26H34N4O3Cor e Forma:SolidPeso molecular:450.57Eucalyptacid A
CAS:<p>Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)</p>Fórmula:C17H32O5Cor e Forma:SolidPeso molecular:316.43ICMT-IN-40
CAS:<p>ICMT-IN-40 (compound 19) is a potent inhibitor of ICMT, exhibiting an IC50 value of 0.031 μM [1].</p>Fórmula:C22H29NOCor e Forma:SolidPeso molecular:323.47IDH1 Inhibitor 2
CAS:<p>IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).</p>Fórmula:C26H22N4OPureza:98%Cor e Forma:SolidPeso molecular:406.48Anticancer agent 122
CAS:<p>Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use in</p>Fórmula:C18H15ClN2O2SCor e Forma:SolidPeso molecular:358.84Benzoic acid lithium
CAS:<p>Lithium benzoate, an aromatic alcohol present in numerous plants, commonly serves as an additive in food, beverages, cosmetics, and various other products. This compound exhibits antibacterial and antifungal properties, functioning effectively as a preservative [1].</p>Fórmula:C7H5LiO2Cor e Forma:SolidPeso molecular:128.06G43-C3-TEG
CAS:<p>G43-C3-TEG is a glycosyl-transferase inhibitor that diminishes biofilm formation by inhibiting the synthesis of extracellular polysaccharides (EPS) [1].</p>Fórmula:C24H27N3O9SCor e Forma:SolidPeso molecular:533.551-Myristoyl-2-Palmitoyl-3-Butyryl-rac-glycerol
CAS:<p>1-Myristoyl-2-palmitoyl-3-butyryl-rac-glycerol, a triacylglycerol with myristic acid (at the sn-1 position), palmitic acid (at the sn-2 position), and butyric acid (at the sn-3 position), has been detected in human breast milk.</p>Fórmula:C37H70O6Cor e Forma:SolidPeso molecular:611ICMT-IN-24
CAS:<p>ICMT-IN-24 (compound 63) is an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting potent activity with an IC50 value of 0.19 μM [1].</p>Fórmula:C22H28ClNO2Cor e Forma:SolidPeso molecular:373.9212-OAHSA
CAS:<p>Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are recently discovered lipids that play a role in the body's response to fasting and high-fat diets, with a link to insulin sensitivity. These compounds consist of a long-chain fatty acid (such as palmitoleic, palmitic, oleic, or stearic acid) bonded to a hydroxy fatty acid, both ranging in length from C-16 to C-18. Specifically, 12-OAHSA is a type of FAHFA where oleic acid is attached to the 12th carbon of hydroxy stearic acid. Within the FAHFA family, OAHSAs are particularly notable for their high concentration in the serum of AG4OX mice, a strain engineered to express the Glut4 glucose transporter predominantly in their adipose tissue, which demonstrates an enhanced glucose tolerance.</p>Fórmula:C36H68O4Cor e Forma:SolidPeso molecular:564.9ICMT-IN-11
CAS:<p>ICMT-IN-11 (compound 48) serves as an ICMT inhibitor with an IC50 value of 0.031 μM [1].</p>Fórmula:C22H27F2NO2Cor e Forma:SolidPeso molecular:375.45ICMT-IN-2
CAS:<p>ICMT-IN-2 (compound 45) serves as an ICMT inhibitor with an IC50 value of 0.168 μM [1].</p>Fórmula:C21H26FNOCor e Forma:SolidPeso molecular:327.4412,15-epoxy-13-methyl-12,14-Eicosadienoic Acid
CAS:<p>12,15-Epoxy-13-methyl-12,14-eicosadienoic acid, a furan fatty acid first identified in northern pike (E. lucius), exhibits elevated levels in the liver of starving cod.</p>Fórmula:C21H36O3Cor e Forma:SolidPeso molecular:336.51Desacetyl bisacodyl
CAS:<p>Desacetyl bisacodyl, the active metabolite of the laxative bisacodyl, evokes epithelial Cl(-) secretion in the rat colon and rectum, in addition to increasing</p>Fórmula:C18H15NO2Pureza:98%Cor e Forma:SolidPeso molecular:277.3212-SAHSA
CAS:<p>Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids recently discovered to be modulated by dietary influences such as fasting and high-fat feeding, and they play a role in enhancing insulin sensitivity. These compounds typically feature a carbon-16 or carbon-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) esterified to a carbon-16 or carbon-18 hydroxy fatty acid. A specific example is 12-SAHSA, which consists of stearic acid linked to 12-hydroxy stearic acid. Notably, 12-SAHSA levels are found to be moderately increased in the serum of glucose tolerant AG4OX mice, a model characterized by adipose tissue-specific overexpression of the Glut4 glucose transporter.</p>Fórmula:C36H70O4Cor e Forma:SolidPeso molecular:566.9529-SAHSA
CAS:<p>Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids that are modulated by dietary changes such as fasting and high-fat diets, and they play a role in insulin sensitivity. These compounds generally consist of a fatty acid chain of either 16 or 18 carbons (for example, palmitoleic, palmitic, oleic, or stearic acid) esterified to a similarly long hydroxy fatty acid. One specific FAHFA, 9-SAHSA, features stearic acid esterified at the 9th carbon of hydroxy stearic acid. The concentration of 9-SAHSA is notably increased in the serum of glucose-tolerant AG4OX mice, which specifically express the Glut4 glucose-transporting protein in adipose tissue.</p>Fórmula:C36H70O4Cor e Forma:SolidPeso molecular:566.9MR-2-93-3
CAS:<p>MR-2-93-3, a long-chain fatty acid, functions as a carrier for polynucleotides [1].</p>Fórmula:C89H150N2O8Cor e Forma:SolidPeso molecular:1376.15PTP1B-IN-20
<p>PTP1B-IN-20: Selective PTP1B inhibitor, IC50=1.05μM; less effective on TCPTP (IC50=78μM), targets type 2 diabetes.</p>Fórmula:C26H28O15Cor e Forma:SolidPeso molecular:580.49C14-SPM
CAS:<p>C14-SPM, a branched-chain polyamine lipidoid, facilitates the delivery of siRNA [1].</p>Fórmula:C94H194N4O6Cor e Forma:SolidPeso molecular:1476.57ICMT-IN-39
CAS:<p>ICMT-IN-39, also known as compound 18, functions as an inhibitor of ICMT with an IC50 value of 0.031 µM [1].</p>Fórmula:C22H29NOCor e Forma:SolidPeso molecular:323.47Lp-PLA2-IN-2
CAS:<p>Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.</p>Fórmula:C19H23FN2O4SPureza:98%Cor e Forma:SolidPeso molecular:394.461,2-Dilauroyl-sn-glycero-3-PA sodium
CAS:<p>DLPA is a phosphatidic acid (PA) that incorporates the medium-chain lauric acid (12:0).</p>Fórmula:C27H52O8PNaCor e Forma:SolidPeso molecular:558.66ERX-41
CAS:<p>ERX-41 is an orally active, stereospecific small molecule that targets lysosomal acid lipase A (LIPA).</p>Fórmula:C38H48N4O9Pureza:98%Cor e Forma:SolidPeso molecular:704.81MS-444
CAS:<p>MS-444 (BE-34776) is an MLCK and HuR inhibitor with antitumor activity that can be used to study triple-negative breast cancer and colorectal cancer.</p>Fórmula:C13H10O4Pureza:99.45% - 99.45%Cor e Forma:SolidPeso molecular:230.22Hypusine
CAS:<p>Hypusine is an N-terminal amino alcohol derivative of Lys occurring in bovine brain &</p>Fórmula:C10H23N3O3Cor e Forma:SolidPeso molecular:233.31EMT inhibitor-2
CAS:<p>EMT inhibitor-2 blocks CYP3A4 and CYP2C9 (IC50: 49.72, 5.54 μM) and prevents IL-1β/TGF-β-induced EMT.</p>Fórmula:C24H26N2O8Cor e Forma:SolidPeso molecular:470.47PDE1-IN-2
CAS:<p>PDE1-IN-2 is an PDE1 inhibitor(PDE1C, PDE1B and PDE1A with IC50 values of 6, 140 and 164 nM, respectvely).</p>Fórmula:C16H21BrN4O2Pureza:98%Cor e Forma:SolidPeso molecular:381.27FABP4/5-IN-4
CAS:<p>FABP4/5-IN-4 (compound E1) effectively inhibits FABP 4 and FABP 5, displaying IC50 values of 3.78 μM and 5.72 μM, respectively. It is significant in the management of metabolic disorders such as diabetes mellitus [1].</p>Fórmula:C26H21F2NO5SCor e Forma:SolidPeso molecular:497.51BAY-7081
<p>BAY-7081 is a cyanopyridone-based compound that functions as a potent, selective, and orally active PDE9A inhibitor, demonstrating an inhibition concentration (</p>Fórmula:C19H27ClN4OCor e Forma:SolidPeso molecular:362.9HIF-2α-IN-6
CAS:<p>HIF-2α-IN-6 (117) is a HIF-2α inhibitor [1].</p>Fórmula:C15H13F4NO3SCor e Forma:SolidPeso molecular:363.33VT-1598 tosylate
CAS:<p>VT-1598 tosylate is a selective, orally active antifungal compound that targets CYP51. It demonstrates efficacy against C. auris.</p>Fórmula:C38H28F4N6O5SCor e Forma:SolidPeso molecular:756.72LXR agonist 1
CAS:<p>Potent LXR agonist; AC50: 1.5 nM (LXR-α), 12 nM (LXR-β); potential in atherosclerosis research.</p>Fórmula:C27H26F3N3O3SCor e Forma:SolidPeso molecular:529.57Brodimoprim
CAS:<p>Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).</p>Fórmula:C13H15BrN4O2Pureza:98% - 98.33%Cor e Forma:SolidPeso molecular:339.19Enpp-1-IN-4
CAS:<p>Enpp-1-IN-4: potent enpp-1 inhibitor with potential in cancer research. See patent WO2019177971A1, compound 1.</p>Fórmula:C19H19N5O5SCor e Forma:SolidPeso molecular:429.45BMS-795311
CAS:<p>Potent CETP inhibitor, boosts HDL-C levels, orally active; IC50=4nM.</p>Fórmula:C33H23F10NO3Cor e Forma:SolidPeso molecular:671.52IDO1/2-IN-1 hydrochloride
CAS:<p>IDO1/2-IN-1 hydrochloride: Dual IDO1/2 inhibitor, IC50 of 28/144 nM, oral, with antitumor properties.</p>Fórmula:C16H19BrClFN8O4Cor e Forma:SolidPeso molecular:521.73HIF-2α-IN-9
CAS:<p>HIF-2α-IN-9 (compound 35r) serves as an HIF-2α inhibitor, effectively suppressing VEGF-A with an IC50 of 305 nM, and modulating growth-promoting genes within</p>Fórmula:C12H13F5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:380.35Quizalofop-P
CAS:<p>Quizalofop-P, a selective herbicide, is absorbed by weed stems and leaves before translocating both upward and downward within the plant, concentrating in</p>Fórmula:C17H13ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:344.75Entacapone acid
CAS:<p>Entacapone acid (AG 1290) is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).</p>Fórmula:C10H6N2O6Pureza:98.86%Cor e Forma:SolidPeso molecular:250.164BAB
CAS:<p>4BAB (compound 29) is an irreversible inhibitor of glyoxalase I (GLO1) and exhibits anticancer activity.</p>Fórmula:C18H28BrN3O10SCor e Forma:SolidPeso molecular:558.4ICMT-IN-34
CAS:<p>ICMT-IN-34 (compound 39) serves as an effective inhibitor of ICMT, exhibiting an IC50 value of 0.17 μM [1].</p>Fórmula:C21H25Cl2NOCor e Forma:SolidPeso molecular:378.34Kelatorphan
CAS:<p>Kelatorphan is an enkephalin degrading enzyme full inhibitor.</p>Fórmula:C14H18N2O5Pureza:98%Cor e Forma:SolidPeso molecular:294.313,14-dihydro-15(R)-Prostaglandin E1
CAS:<p>13,14-Dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)-PGE1) is an analog of 13,14-dihydro-PGE1 characterized by its R-configured hydroxyl group at the C-15 position [1].</p>Fórmula:C20H36O5Cor e Forma:SolidPeso molecular:356.503Tetrahydro-11-dehydrocorticosterone
CAS:<p>Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].</p>Fórmula:C21H32O4Cor e Forma:SolidPeso molecular:348.48Carbonic anhydrase inhibitor 12
CAS:<p>CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.</p>Fórmula:C27H22BrN5O5S2Pureza:98%Cor e Forma:SolidPeso molecular:640.53Mal-Pc
CAS:<p>Mal-Pc, a maleimide phthalocyanine, depletes GSH to reduce aggregation and boost ROS, improving PDT against cancer.</p>Fórmula:C46H28N10O8SiPureza:98%Cor e Forma:SolidPeso molecular:876.86ICMT-IN-1
CAS:<p>ICMT-IN-1 (compound 75) is a potent ICMT inhibitor with an IC50 value of 0.0013 μM.</p>Fórmula:C24H33NO2Cor e Forma:SolidPeso molecular:367.52CETP-IN-3
CAS:<p>CETP-IN-3 is an inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP.</p>Fórmula:C30H24F12N2O4Pureza:98%Cor e Forma:SolidPeso molecular:704.5Oseltamivir acid methyl ester
CAS:<p>Oseltamivir acid methyl ester, a CES1-convertible neuraminidase inhibitor, serves as an antiviral prodrug.</p>Fórmula:C15H26N2O4Pureza:98.78%Cor e Forma:SolidPeso molecular:298.38Ilepatril
CAS:<p>Ilepatril, also known as AVE-7688, is a vasopeptidase inhibitor for the treatment of hypertension.</p>Fórmula:C22H28N2O5SCor e Forma:SolidPeso molecular:432.53
