Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8625 produtos de "Metabolismo"
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SHP2-IN-34
CAS:<p>SHP2-IN-34 (compound A8) is a phenylurea SHP2 inhibitor with anti-cancer properties. It significantly suppresses tumor growth in CT26 mouse models.</p>Fórmula:C23H25Cl2N7OSCor e Forma:SolidPeso molecular:518.46Phenolic acid
CAS:<p>Phenolic acid is an endogenous metabolite.</p>Fórmula:C7H8D2O3Pureza:98%Cor e Forma:SolidPeso molecular:144.16QXG-6442
<p>QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.</p>Fórmula:C21H17N5O4Cor e Forma:SolidPeso molecular:403.39α-glucosidase/PTP1B-IN-1
<p>α-glucosidase/PTP1B-IN-1 (compound 8a) is an effective inhibitor of both α-glucosidase and PTP1B, with IC50 values of 66.3 μM and 47.0 μM, respectively. It also exhibits strong inhibitory activity against α-amylase, having an IC50 of 30.62 μM. This compound is capable of binding to the active sites of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 holds potential for reducing postprandial blood glucose levels and may be useful in managing type 2 diabetes.</p>Fórmula:C23H20Cl2O5Cor e Forma:SolidPeso molecular:447.31Coumachlor
CAS:<p>Coumachlor, a first-generation anticoagulant rodenticide, blocks the formation of prothrombin and inhibits blood coagulation causing internal haemorrhage.</p>Fórmula:C19H15ClO4Cor e Forma:SolidPeso molecular:342.77Canadensolide
CAS:<p>Canadensolide is an antifungal metabolite of Penicillium canadense .</p>Fórmula:C11H14O4Cor e Forma:SolidPeso molecular:210.23Ercalcidiol
CAS:<p>Ercalcidiol is a metabolite of vitamin D2 and can be used in monitoring vitamin D therapy.</p>Fórmula:C28H44O2Pureza:99.62%Cor e Forma:SolidPeso molecular:412.65TMP-778
CAS:<p>TMP-778 is a selective inverse agonist of RORγt.</p>Fórmula:C31H30N2O4Pureza:99.68%Cor e Forma:SolidPeso molecular:494.58AV22-149
<p>AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .</p>Fórmula:C23H28F3N3O6S2Cor e Forma:SolidPeso molecular:563.61BMS 195614
CAS:<p>BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.</p>Fórmula:C29H24N2O3Pureza:97.7%Cor e Forma:SolidPeso molecular:448.51IR-117-17
CAS:<p>IR-117-17 is an ionizable cationic amino lipid that targets the airways. It is degradable via esterase cleavage, making it less likely to accumulate with repeated dosing.</p>Fórmula:C59H110N2O5Cor e Forma:SolidPeso molecular:927.522-Chlorophenylboronic acid
CAS:<p>2-Chlorophenylboronic acid: A monohalogenated phenylboronic acid used in drug synthesis and as a fatty acid amidase inhibitor.</p>Fórmula:C6H6BClO2Pureza:99.42%Cor e Forma:SolidPeso molecular:156.37Asperlactone
CAS:<p>Asperlactone is a nematicidal, insecticidal, antibacterial, and antifungal polyketide metabolite produced from A. westerdijkiae.</p>Fórmula:C9H12O4Cor e Forma:SolidPeso molecular:184.191N-Lactylvaline
CAS:<p>N-Lactylvaline is an endogenous metabolite detectable in patients with intermediate maple syrup urine disease.</p>Fórmula:C8H15NO4Cor e Forma:SolidPeso molecular:189.21LQ-38
<p>LQ-38 is an orally active, soluble epoxide hydrolase (sEH) inhibitor with an IC50 value of 5.2 nM. It has shown anti-inflammatory activity in rat foot edema models and in mouse models of acute pancreatitis, and exhibits analgesic effects in acetic acid-induced mouse writhing models.</p>Fórmula:C42H68N2O9Cor e Forma:SolidPeso molecular:745.004-methyl-2-Oxovalerate (sodium salt)
CAS:<p>4-Methyl-2-oxovalerate is an L-leucine precursor/metabolite and a key compound in 2-methylpropyl glucosinolate synthesis and diabetes marker.</p>Fórmula:C6H9NaO3Cor e Forma:SolidPeso molecular:152.12Prenisteine
CAS:<p>Prenisteine is a bioactive chemical.</p>Fórmula:C8H15NO2SCor e Forma:SolidPeso molecular:189.275(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
CAS:<p>(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups.</p>Fórmula:C10H18N2O2S2Cor e Forma:SolidPeso molecular:262.39Flumethasone 21-acetate
CAS:<p>Flumethasone 21-acetate is an anti-inflammatory corticosteroid.</p>Fórmula:C24H30F2O6Cor e Forma:SolidPeso molecular:452.49RARα antagonist 1
<p>Compound 21, an orally active and selective RARα antagonist, exhibits a potent inhibition of the retinoic acid receptor α with an IC50 of 4.6 nM [1].</p>Fórmula:C26H23NO4Cor e Forma:SolidPeso molecular:413.47L,L-Dityrosine
CAS:<p>L,L-Dityrosine, a component found in the acid hydrolysates of various biological materials, such as insect cuticular resilin, plays a significant role in</p>Fórmula:C18H20N2O6Pureza:98%Cor e Forma:SolidPeso molecular:360.365-hydroxy Indomethacin
CAS:<p>5-hydroxy Indomethacin is a metabolite of indomethacin .1It is formed from indomethacin in rabbit hepatic microsomes.</p>Fórmula:C18H14ClNO4Cor e Forma:SolidPeso molecular:343.76ZG-2305
<p>ZG-2305 is an effective, selective, and orally active inhibitor of FIH (factor inhibiting hypoxia-inducible factor (FIH)), with Ki values of 79.6 nM for FIH and 2786 nM for PHD2. This compound enhances the expression of the EGLN3 gene, reduces cellular triglyceride levels, and decreases lipid accumulation. ZG-2305 holds potential for research into obesity and fatty liver disease.</p>Fórmula:C17H11Cl2N3O5Cor e Forma:SolidPeso molecular:408.19BAY 2666605
CAS:<p>BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.</p>Fórmula:C17H12F4N2O2Pureza:99.81%Cor e Forma:SolidPeso molecular:352.28sPLA2 inhibitor 3
<p>sPLA2 inhibitor 3 (Compound 6c) functions as a potent α-glucosidase inhibitor (IC50= 0.0953 µM) and has potential applications in diabetes research.</p>Fórmula:C22H16F6N6O4S2Cor e Forma:SolidPeso molecular:606.52β-1, 3-N-Acetylhexaminyltransferase (LgtA)
CAS:<p>LgtA is a glycosyltransferase that adds N-acetylglucosamine to lactose and N-acetyllactosamine.</p>Cor e Forma:SolidNepetalactone
CAS:<p>Nepetalactone is found in the plant Nepeta parnassica and has high mosquito repellency properties.</p>Fórmula:C10H14O2Cor e Forma:SolidPeso molecular:166.22Hydroxychloroquine Impurity F
CAS:<p>Hydroxychloroquine Impurity F, a byproduct, is an antimalarial that blocks TLR7/9 and inhibits SARS-CoV-2 in vitro.</p>Fórmula:C14H15ClN2Cor e Forma:SolidPeso molecular:246.74ROS-IN-3
<p>ROS-IN-3 (compound x38) is an inhibitor of ROS and is utilized in neuro-related research.</p>Fórmula:C25H20F2N2O4Cor e Forma:SolidPeso molecular:450.43PDE4-IN-3
CAS:<p>PDE4-IN-3, a new oral drug, potently blocks PDE4 enzyme with 4.2 nM IC50.</p>Fórmula:C35H33FO8Cor e Forma:SolidPeso molecular:600.639Moth Cytochrome C (MCC) (88-103)
CAS:<p>Moth Cytochrome C (88-103) peptide induces positive TCR selection in thymocytes; key for self-tolerant T cell development.</p>Fórmula:C79H133N23O25Pureza:98%Cor e Forma:SolidPeso molecular:1805.04IGUANA-1
CAS:<p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>Fórmula:C27H26ClN3O4Pureza:99.08%Cor e Forma:SolidPeso molecular:491.97L-739750 2HCl
<p>L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.</p>Fórmula:C23H41Cl2N3O6S2Pureza:98.69% - 99.16%Cor e Forma:SoildPeso molecular:590.62DSPE-PEG5000-CREKA
<p>DSPE-PEG5000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide is utilized for targeting tumor cells and tumor vasculature, exhibiting anti-tumor activity. DSPE-PEG5000-CREKA is applicable in drug delivery systems.</p>Cor e Forma:Odour SolidBenzoic acid (Standard)
CAS:<p>Benzoic acid (Standard) is a standard substance for quantitative analysis.Benzoic acid (Dracylic acid) is an aromatic alcohol and common additive.</p>Fórmula:C7H6O2Pureza:99.99%Cor e Forma:White Solid Monoclinic Tablets Plates LeafletsPeso molecular:122.12Pyrocholecalciferol
CAS:<p>Pyrocholecalciferol, a vitamin D analogue, is produced through the photochemical transformation of 7-dehydrocholesterol (7-DHC) [1] [2].</p>Fórmula:C27H44OCor e Forma:SolidPeso molecular:384.64Isariin C
CAS:<p>Isariin C is a flavonoid glucoside derived from the Epimedium plant genus. It stimulates angiogenesis and exhibits antioxidant activity.</p>Fórmula:C28H49N5O7Cor e Forma:SolidPeso molecular:567.7221-Deoxy Cortisone
CAS:<p>21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.</p>Fórmula:C21H28O4Cor e Forma:SolidPeso molecular:344.44CRCD2
CAS:<p>1H-Benzimidazole-6-carboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-可能具有抗肿瘤活性。</p>Fórmula:C17H16N4O2SPureza:99.52%Cor e Forma:SoildPeso molecular:340.4AY 9944 dihydrochloride
CAS:<p>AY 9944 dihydrochloride is a intermediate.</p>Fórmula:C22H30Cl4N2Pureza:99.22% - 99.82%Cor e Forma:SoildPeso molecular:464.3GPX4-IN-16
<p>GPX4-IN-16 ((R)-9i) is a potent inhibitor of GPX4 with a KD value of 20.4 nM, exhibiting cytotoxic properties and anticancer activity.</p>Fórmula:C29H24N4O3S2Cor e Forma:SolidPeso molecular:540.6562,3-Indolobetulin
CAS:<p>2,3-Indolobetulin is a pentacyclic triterpenoid and derivative of betulin .1It has been used in the synthesis of α-glucosidase inhibitors.</p>Fórmula:C36H51NOCor e Forma:SolidPeso molecular:513.815,6-epoxy-13-cis Retinoic Acid
CAS:<p>5,6-epoxy-13-cis Retinoic Acid is a metabolite of 13-cis retinoic acid.</p>Fórmula:C20H28O3Cor e Forma:SolidPeso molecular:316.441CA Ⅱ-IN-1
<p>CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.</p>Fórmula:C18H19NO6SCor e Forma:SolidPeso molecular:377.41GLUT inhibitor-1
CAS:<p>GLUT inhibitor-1: oral, targets GLUT1/3 (IC50: 242/179 nM), for cancer/autoimmune research.</p>Fórmula:C32H35N7O2Pureza:98.12%Cor e Forma:SolidPeso molecular:549.67Vitamin B12a hydrochloride
CAS:<p>Vitamin B12a monohydrochloride (Hydroxocobalamin) is an essential water-soluble vitamin.a cyanide detoxifier and nutritional supplement, injection, inhalation.</p>Fórmula:C62H89CoN13O15P·xHClCor e Forma:SolidErucic acid sodium
CAS:<p>Erucic acid sodium, a monounsaturated fatty acid (MUFA) extracted from the seeds of rapeseed, readily crosses the blood-brain barrier (BBB). It normalizes the accumulation of long-chain fatty acids in the brain, enhances cognitive function, and effectively prevents dementia.</p>Fórmula:C22H42NaO2Cor e Forma:SolidPeso molecular:361.56α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Fórmula:C25H22N6OS2Cor e Forma:SolidPeso molecular:486.61Calcium Channel antagonist 4
CAS:<p>Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Fórmula:C23H26N2O4SPureza:98.09%Cor e Forma:SolidPeso molecular:426.53tetranor-12(S)-HETE
CAS:<p>12(S)-HETE, from arachidonic acid via 12-lipoxygenase, is found in platelets and leukocytes, aids tumor cell adhesion, with a derivative used in research.</p>Fórmula:C16H26O3Cor e Forma:SolidPeso molecular:266.381
