Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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Maximiscin
CAS:<p>Maximiscin, a metabolite derived from fungi, causes DNA damage and exhibits selective cytotoxic activity towards a specific subtype of triple-negative breast</p>Fórmula:C23H31NO8Cor e Forma:SolidPeso molecular:449.49TKL-IN-1
<p>TKL-IN-1 (compound 7r) serves as an inhibitor of transketolase (Transketolase) and can be utilized as an herbicide. This compound effectively hampers the growth of Digitaria sanguinalis (Ds) and Amaranthus retroflexus (Ar).</p>Fórmula:C20H12ClN5OS2Cor e Forma:SolidPeso molecular:437.93N-Desethyl Bimatoprost
CAS:<p>N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide.</p>Fórmula:C23H33NO4Cor e Forma:SolidPeso molecular:387.51N-Acetyl-Ser-Asp-Lys-Pro TFA
N-Acetyl-Ser-Asp-Lys-Pro (TFA), a bone marrow tetrapeptide, is a specific ACE substrate for angiotensin conversion.Fórmula:C22H34F3N5O11Pureza:98%Cor e Forma:SolidPeso molecular:601.53Trimipramine N-oxide
CAS:<p>Trimipramine N-oxide, a trimipramine metabolite, inhibits hNAT, hSERT, hDAT, and hOCT1/2 with IC50s 11.7-27.4 nM; for depression/anxiety research.</p>Fórmula:C20H26N2OCor e Forma:SolidPeso molecular:310.43γ-Glu-Gly TFA
<p>γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid).</p>Cor e Forma:LiquidDSPE-PEG1000-CTT2
<p>DSPE-PEG1000-CTT2 is a PEG compound comprised of DSPE and a gelatinase inhibitor [CTT2 (CTTHWGFTLC)]. The CTT2 (CTTHWGFTLC) peptide is capable of specifically targeting tumors. DSPE-PEG1000-CTT2 can be utilized for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG5000-K237
<p>DSPE-PEG5000-K237 is a PEG compound composed of DSPE and the KDR-targeting peptide (K237). K237 effectively disrupts the interaction between VEGF and KDR receptors, yielding significant biological effects, such as inhibiting angiogenesis and tumor growth. DSPE-PEG5000-K237 is applicable for drug delivery.</p>Cor e Forma:Odour SolidMethyl gerfelin
CAS:<p>Methyl gerfelin, a flavonoid, hinders osteoclast formation by targeting GLO1, SCP2, and SGTA proteins.</p>Fórmula:C16H16O6Cor e Forma:SolidPeso molecular:304.29Sialyl-Lewis X
CAS:<p>sLeX: sialylated, fucosylated tetrasaccharide, ligand for selectins, inhibits neutrophil recruitment.</p>Fórmula:C31H52N2O23Cor e Forma:SolidPeso molecular:820.7488-Isoprostaglandin F2α
CAS:<p>8-Isoprostaglandin F2α is a natural product for research related to life sciences. The catalog number is T37164 and the CAS number is 27415-26-5.</p>Fórmula:C20H34O5Cor e Forma:SolidPeso molecular:354.481,4-Butanediamine
CAS:<p>1, 4-butanediamine is an aliphatic diamine compound that can be used as an analytical reagent to assist in precise detection experiments and also as a dye intermediate to facilitate the synthesis of various functional dyes.</p>Fórmula:C4H12N2Cor e Forma:SolidPeso molecular:88.1515KKII5
CAS:<p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>Fórmula:C16H14N2SPureza:99.34%Cor e Forma:SolidPeso molecular:266.36PDE5-IN-10
<p>PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM,</p>Fórmula:C21H20N4O2Cor e Forma:SolidPeso molecular:360.41Atocalcitol
CAS:<p>Atocalcitol is a vitamin D analog. It also acts as an agonist of alcitriol receptor.</p>Fórmula:C32H46O4Pureza:98%Cor e Forma:SolidPeso molecular:494.718,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside
CAS:<p>8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside (Compound 3), a natural product isolated from Bidens bipinnata, exhibits a 22% inhibition against α-amylase at</p>Fórmula:C21H20O11Cor e Forma:SolidPeso molecular:448.38DSPE-PEG5000-EB1
<p>DSPE-PEG5000-EB1 is a PEGylated compound composed of DSPE and the pH-responsive transmembrane peptide (EB1). It is useful for drug delivery applications.</p>Cor e Forma:Odour Solid4-Hydroxyphenylbutazone
CAS:<p>4-Hydroxyphenylbutazone, a Phenylbutazone metabolite, enhances PHS's peroxidase activity as an NSAID.</p>Fórmula:C19H20N2O3Cor e Forma:SolidPeso molecular:324.385-(3'-Hydroxyphenyl)-γ-Valerolactone
CAS:<p>5-(3'-Hydroxyphenyl)-γ-valerolactone, a metabolite resulting from the transformation of polyphenols such as (+)-catechin and (−)-epicatechin by gut microbiota,</p>Fórmula:C11H12O3Cor e Forma:SolidPeso molecular:192.21Sofosbuvir impurity B
<p>Sofosbuvir impurity B, a less active byproduct, inhibits HCV RNA with potent anti-HCV effects.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45CBS-1114 HCl
CAS:<p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>Fórmula:C13H14ClN3Pureza:99.36%Cor e Forma:SoildPeso molecular:247.72Glutarylcarnitine lithium
<p>Glutarylcarnitine lithium indicates malonic aciduria, glutaric aciduria I in newborn screenings.</p>Fórmula:C12H20LiNO6Cor e Forma:SolidPeso molecular:281.23DSPE-PEG5000-KAA
<p>DSPE-PEG5000-KAA is a PEG compound composed of DSPE and the CKAAKNK (KAA) peptide. The CKAAKNK peptide specifically targets the tumor vasculature of RIP-Tag2 transgenic mice. DSPE-PEG5000-KAA can be utilized for drug delivery purposes.</p>Cor e Forma:Odour SolidIrsogladine maleate
CAS:<p>Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H7Cl2N5Cor e Forma:SolidPeso molecular:256.09Trifluoperazine N-Glucuronide
CAS:<p>Trifluoperazine N-Glucuronide is a metabolite of Trifluoperazine with antidepressant and antipsychotic activity.</p>Fórmula:C27H32F3N3O6SCor e Forma:SolidPeso molecular:583.62Mebeverine acid
CAS:<p>Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.</p>Fórmula:C16H25NO3Pureza:99.66%Cor e Forma:SolidPeso molecular:279.37Diphlorethohydroxycarmalol
CAS:<p>Diphlorethohydroxycarmalol is a useful organic compound for research related to life sciences and the catalog number is T125953.</p>Fórmula:C24H16O13Cor e Forma:SolidPeso molecular:512.379Pi-Methylimidazoleacetic acid
CAS:<p>Pi-Methylimidazoleacetic acid is a potential neurotoxin.</p>Fórmula:C6H8N2O2Pureza:98%Cor e Forma:SolidPeso molecular:140.14DSPE-PEG2000-WYRGRL
<p>DSPE-PEG2000-WYRGRL is a PEG compound composed of DSPE and the cartilage-targeting peptide (WYRGRL). The peptide WYRGRL can specifically bind to type II collagen α1. DSPE-PEG2000-WYRGRL is utilized for drug delivery.</p>Cor e Forma:Odour SolidWAY-313170
CAS:<p>WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.</p>Fórmula:C19H17ClN2O2S2Pureza:99.3%Cor e Forma:SolidPeso molecular:404.93Cyclopenol
CAS:<p>Cyclopenol is a natural product that can be used as a reference standard. The CAS number of Cyclopenol is 20007-85-6.</p>Fórmula:C17H14N2O4Cor e Forma:SolidPeso molecular:310.3093-Oxo-7-hydroxychol-4-enoic acid
CAS:<p>3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.</p>Fórmula:C24H36O4Cor e Forma:SolidPeso molecular:388.54CP-610431
CAS:<p>CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.</p>Fórmula:C30H37N3O2Cor e Forma:SolidPeso molecular:471.645(S)-3,4-Dihydroxybutyric acid
CAS:<p>(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.</p>Fórmula:C4H8O4Pureza:98%Cor e Forma:SolidPeso molecular:120.12-Hydroxyquinoline
CAS:<p>Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H7NOCor e Forma:White SolidPeso molecular:145.15Phosphodiesterase
CAS:<p>PDE enzyme hydrolyzes cyclic nucleotides, regulates signal transduction, and varies in type (PDE1-PDE11) with disease research potential.</p>Cor e Forma:SolidRibulose, L-
CAS:<p>Ribulose: key in pentose metabolism, aids L-ribose isomerase study, yeast engineering, and chiral compound research.</p>Fórmula:C5H10O5Cor e Forma:SolidPeso molecular:150.13DSPE-PEG3000-R6H4
<p>DSPE-PEG3000-R6H4 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (R6H4). R6H4 is applicable for pH-responsive anticancer drug delivery. DSPE-PEG3000-R6H4 can be utilized for drug delivery purposes.</p>Cor e Forma:Odour SolidDSPE-PEG2000-THRPPMWSPVWP
<p>DSPE-PEG2000-THRPPMWSPVWP is a PEG compound composed of DSPE and transferrin receptor (TfR) peptide. The sequence THRPPMWSPVWP binds to TfR and is subsequently internalized into cells expressing TfR.</p>Cor e Forma:Odour SolidDSPE-PEG1000-GRGDS
<p>DSPE-PEG1000-GRGDS is a PEG compound composed of DSPE and the anti-adhesion peptide (GRGDS). GRGDS can inhibit the binding and adhesion between the extracellular matrix and cell surface integrins. The compound is useful for drug delivery applications.</p>Cor e Forma:Odour SolidL-Lactate dehydrogenase
CAS:<p>L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.</p>Cor e Forma:SolidNU227326
CAS:<p>NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).</p>Fórmula:C53H61FN8O7Cor e Forma:SolidPeso molecular:941.099MSI-1436 lactate
CAS:<p>MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)</p>Fórmula:C37H72N4O5SC3H6O3Pureza:98%Cor e Forma:SolidPeso molecular:1000.17Echinocandin B
CAS:<p>Echinocandin B: a cyclic hexapeptide from A. nidulans, inhibits fungal cell wall synthesis by blocking beta-1,3-glucan.</p>Fórmula:C52H81N7O16Cor e Forma:SolidPeso molecular:1060.24Hydroorotic acid
CAS:<p>Hydroorotic acid（Dihydroorotic acid） is an endogenous metabolite，a potential biomarker for diabetic nephropathy and adrenal pheochromocytoma.</p>Fórmula:C5H6N2O4Pureza:99.90%Cor e Forma:SolidPeso molecular:158.11CAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Fórmula:C15H17N3O4SPureza:99.07%Cor e Forma:SolidPeso molecular:335.38DSPE-PEG2000-EB1
<p>DSPE-PEG2000-EB1 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (EB1). It is utilized for drug delivery.</p>Cor e Forma:Odour SolidMethylcardol triene
CAS:<p>Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.496(±)15-HEDE
CAS:<p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>Fórmula:C20H36O3Cor e Forma:SolidPeso molecular:324.505hCA/VEGFR-2-IN-4
<p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>Fórmula:C22H23FN6O5SPureza:98%Cor e Forma:SolidPeso molecular:502.52
