Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Lantanose A
CAS:<p>Lantanose A is a bioactive chemical from Lantana cumara roots.</p>Fórmula:C30H52O26Pureza:98%Cor e Forma:SolidPeso molecular:828.72DSPE-PEG5000-VIP
<p>DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the cell-penetrating peptide (TAT) peptide. DSPE-PEG2000-TAT is applicable for drug delivery.</p>Cor e Forma:Odour SolidMevalonic acid 5-pyrophosphate tetralithium
CAS:<p>Mevalonic acid 5-pyrophosphate (also known as 5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite involved in the mevalonate pathway.</p>Fórmula:C6H10Li4O10P2Cor e Forma:SolidPeso molecular:331.853,3'-Bipyridine
CAS:<p>3,3'-Bipyridine is an inhibitor of CYP2A6, CYP3A4, and CYP2B6, and also inhibits gastric acid secretion in rats.</p>Fórmula:C10H8N2Cor e Forma:SolidPeso molecular:156.18IDO1-IN-11
CAS:<p>IDO1-IN-11 is an IDO1 inhibitor with an IC 50 value of 0.6 nM.</p>Fórmula:C22H17ClFN3O3Cor e Forma:SolidPeso molecular:425.84Diaphorase
CAS:<p>Diaphorase from anaerobic sludge catalyzes RDX biotransformation via denitrification.</p>Cor e Forma:SolidAbiraterone N-oxide
CAS:<p>Abiraterone N-oxide is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>Fórmula:C24H31NO2Cor e Forma:SolidPeso molecular:365.51Quercetin 3-(6″-caffeoylsophoroside)
CAS:<p>Quercetin 3-(6″-caffeoylsophoroside) is an orally active compound exhibiting α-amylase inhibitory activity, with an IC50 value of 73.66 μg/mL, and demonstrates</p>Fórmula:C27H40N4O7Cor e Forma:SolidPeso molecular:532.63DSPE-PEG1000-LyP-1
<p>DSPE-PEG1000-LyP-1 is a PEG compound composed of DSPE and a nine-residue peptide (LyP-1). LyP-1 specifically targets tumor-associated lymphatic vessels and macrophages.</p>Cor e Forma:Odour Solid(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
CAS:<p>(S,R,S)-AHPC-C2-amide targets Smad3 degradation and boosts HIF-α; it has anti-fibrotic and renal protective roles.</p>Fórmula:C41H46N6O6SCor e Forma:SolidPeso molecular:750.91Tetomilast
CAS:<p>Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive</p>Fórmula:C19H18N2O4SCor e Forma:SolidPeso molecular:370.42Xanthine oxidase-IN-16
<p>Xanthine oxidase-IN-16 is an effective orally active inhibitor of xanthine oxidase (XO), demonstrating significant therapeutic efficacy in rats with hyperuricemia and an IC50 of 102 nM.</p>Cor e Forma:Odour SolidAP-III-a4 hydrochloride
CAS:<p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>Fórmula:C31H44ClFN8O3Pureza:98%Cor e Forma:SolidPeso molecular:631.18ROR1 ligand-1
<p>ROR1ligand-1 (9-1) serves as the ligand for PROTAC ROR1 degrader-1. By linking with ligands of either the VHL type or CRBN, the first selective and efficient ROR1 PROTAC molecule was designed and synthesized.</p>Fórmula:C23H30BrN7Cor e Forma:SolidPeso molecular:484.44Crotonyl-CoA tetrasodium
<p>Crotonyl-CoA tetrasodium is the tetrasodium salt form of Crotonyl-CoA. It serves as an intermediate in butyrate fermentation and in the metabolism of lysine and tryptophan. This compound plays a crucial role in the metabolism of fatty acids and amino acids.</p>Fórmula:C25H36N7Na4O17P3SCor e Forma:SolidPeso molecular:923.54Seco Rapamycin ethyl ester
<p>Seco Rapamycin ethyl ester, an open-ring metabolite of the Rapamycin derivative, reportedly does not impact mTOR function [1].</p>Fórmula:C53H83NO13Cor e Forma:SolidPeso molecular:942.23Relzomostat
CAS:<p>Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.</p>Fórmula:C24H36F2N2O5Cor e Forma:SolidPeso molecular:470.558SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Fórmula:C18H16IN3O3Cor e Forma:SolidPeso molecular:449.24Ninerafaxstat trihydrochloride
CAS:<p>Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation.</p>Fórmula:C22H32Cl3N3O5Pureza:99.71%Cor e Forma:SoildPeso molecular:524.87α-Glucosidase-IN-84
<p>α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.</p>Fórmula:C25H29N7O3SCor e Forma:SolidPeso molecular:507.6082-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Fórmula:C10H14O2Cor e Forma:SolidPeso molecular:166.22DSPE-PEG5000-TH
<p>DSPE-PEG5000-TH is a PEG compound formed from DSPE and the pH-responsive cell-penetrating peptide (TH). In acidic environments like the tumor microenvironment, TH is activated, allowing it to selectively deliver small molecules, oligonucleotides, proteins, and similar substances into tumor cells.</p>Cor e Forma:Odour Solid6-hydroxy Chlorzoxazone
CAS:<p>6-hydroxy Chlorzoxazone, a chlorzoxazone metabolite, is formed in the liver via CYP2E1.</p>Fórmula:C7H4ClNO3Cor e Forma:White To PinkPeso molecular:185.56Impurity C of Alfacalcidol
CAS:<p>Impurity of Alfacalcidol is an impurity of Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Fórmula:C35H49N3O4Pureza:98%Cor e Forma:SolidPeso molecular:575.78Rostratin C
CAS:<p>Rostratin C, a cytotoxic disulfide, exhibits in vitro cytotoxicity against human colon carcinoma (HCT-116), demonstrating an IC50 value of 0.76 μg/mL.</p>Fórmula:C20H24N2O8S2Cor e Forma:SolidPeso molecular:484.54DSPE-PEG2000-APRPG
<p>DSPE-PEG2000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is utilized in drug delivery applications.</p>Cor e Forma:Odour Solidtetranor-PGAM
CAS:<p>PGE2 is a biomarker for inflammation and disease; its unstable urinary metabolite, tetranor-PGEM, and its byproduct, tetranor-PGAM, indicate biosynthesis.</p>Fórmula:C16H22O6Cor e Forma:SolidPeso molecular:310.346sEH inhibitor-20
<p>sEH inhibitor-20 is a metabolically stable, orally active sEH inhibitor with an IC50 of 0.2 nM. It exhibits significant analgesic and anti-inflammatory properties, making it a promising candidate for researching neuropathic pain.</p>Cor e Forma:Odour SolidStephacidin B
CAS:<p>Stephacidin B, from A. ochraceus, forms avrainvillamide in vitro. Cytotoxic to various cancer cells; induces apoptosis in hepatocarcinoma at 4 μM.</p>Fórmula:C52H54N6O8Cor e Forma:SolidPeso molecular:891.038MC 1046
CAS:<p>MC 1046 is an impurity of Calcipotriol. Calcipotriol is a ligand of VDR-like receptors.</p>Fórmula:C27H38O3Pureza:98%Cor e Forma:SolidPeso molecular:410.59Sofosbuvir impurity B
<p>Sofosbuvir impurity B, a less active byproduct, inhibits HCV RNA with potent anti-HCV effects.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45hBChE-IN-3
<p>hBChE-IN-3 (compound 30) serves as both an activator of carbonic anhydrase (CA) and an inhibitor of cholinesterase (ChE), exhibiting IC50 values of 7.4 nM for AchE and 1.9 nM for BchE. This compound is utilized in the research of neurodegenerative and psychiatric disorders.</p>Cor e Forma:Odour SolidSGK1-IN-4
CAS:<p>SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.</p>Fórmula:C23H21ClFN5O4SPureza:97.03%Cor e Forma:SolidPeso molecular:517.96Hydroxy desmethyl Bosentan
CAS:<p>Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver.</p>Fórmula:C26H27N5O7SPureza:98%Cor e Forma:SolidPeso molecular:553.59Cholesterol glucuronide
CAS:<p>Cholesterol glucuronide is an endogenous metabolite of lipid generated by UDP glucuonyltransferase in the liver.</p>Fórmula:C33H54O7Pureza:98%Cor e Forma:SolidPeso molecular:562.78Ser-Ala-alloresact acetate
<p>Ser-Ala-alloresact acetate is a sperm-activating peptide (SAP) that is released by marine invertebrate eggs and plays an important role in fertilization.</p>Fórmula:C44H75N13O16S2Pureza:99.73%Cor e Forma:SolidPeso molecular:1106.28L-Glutamic acid ammonium
CAS:<p>L-Glutamic acid ammonium is an excitatory neurotransmitter.</p>Fórmula:C5H12N2O4Cor e Forma:SolidPeso molecular:164.16Phosphoramidon
CAS:<p>Phosphoramidon inhibits metallo-endopeptidase, endothelin-converting enzyme, and thermolysin; derived from Streptomyces tanashiensis culture.</p>Fórmula:C23H34N3O10PPureza:98%Cor e Forma:SolidPeso molecular:543.5CAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Cor e Forma:Odour SolidAxl-IN-16
<p>Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor activity along with receptor</p>Fórmula:C14H19ClO8Pureza:98%Cor e Forma:SolidPeso molecular:350.75Trityl olmesartan medoxomil impurity III
CAS:<p>Trityl olmesartan medoxomil impurity III is an intermediate impurity in Olmesartan medoxomil synthesis.</p>Fórmula:C48H42N6O5Cor e Forma:SolidPeso molecular:782.88Thymidine 5′-diphosphate
CAS:<p>Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed</p>Fórmula:C10H16N2O11P2Cor e Forma:SolidPeso molecular:402.19DSPE-PEG1000-TH
<p>DSPE-PEG1000-TH is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (TH). In acidic environments, such as the tumor microenvironment, TH is activated, enabling the selective delivery of small molecules, oligonucleotides, proteins, and other agents into tumor cells.</p>Cor e Forma:Odour SolidPenicitide A
CAS:<p>Penicitide A: marine metabolite, moderately cytotoxic to A. brassicae, HepG2 cells.</p>Fórmula:C18H34O4Cor e Forma:SolidPeso molecular:314.46Dios-Arg (trifluoroacetate salt)
CAS:<p>Dios-Arg, a steroid cationic lipid, binds DNA for transfection, but is cytotoxic to H1299/HeLa cells at 83.5/74.1 μg/ml IC50s.</p>Fórmula:C43H67F6N5O9Cor e Forma:SolidPeso molecular:912.01(±)9-HODE cholesteryl ester
CAS:<p>(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.</p>Fórmula:C45H76O3Cor e Forma:SolidPeso molecular:665.1ALR2-IN-1
CAS:<p>ALR2-IN-1: potent, selective inhibitor of ALR2 (IC50=1.42 μM), antiglycemic, antioxidant; for diabetes research.</p>Fórmula:C16H17N3O2SPureza:98.79%Cor e Forma:SoildPeso molecular:315.39Cystocholic acid
CAS:<p>Cystocholic acid is a metabolite of bile acids, possessing antimicrobial potential.</p>Fórmula:C27H45NO7Cor e Forma:SolidPeso molecular:495.65Angiotensin I-13C6,15N (human, mouse, rat) TFA
<p>Angiotensin I-13C6,15N (human, mouse, rat) TFA is a labeled version of Angiotensin I, using isotopes 13C and 15N, specifically targeted for human, mouse, and rat studies. This compound serves as a precursor to angiotensin II, which is formed through the cleavage by angiotensin-converting enzyme (ACE).</p>Fórmula:C5713C6H89N1615NO14·xC2HF3O2Cor e Forma:SolidPeso molecular:1303.42 (free base)(Rac)-Mono(3,5,5-trimethylhexyl) phthalate
CAS:<p>(Rac)-Mono(3,5,5-trimethylhexyl) phthalate: a key metabolite of phthalate plasticizers with immune-suppressing effects.</p>Fórmula:C17H24O4Cor e Forma:SolidPeso molecular:292.37
