Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(271 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(98 produtos)
- Lipídio(58 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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ZK824859
CAS:<p>ZK824859 is an oral uPA inhibitor with IC50s: 79 nM (uPA), 1580 nM (tPA), 1330 nM (plasmin).</p>Fórmula:C23H22F2N2O4Pureza:98%Cor e Forma:SolidPeso molecular:428.439(Z),11(E)-Conjugated Linoleic Acid methyl ester
CAS:<p>9(Z),11(E)-Conjugated Linoleic Acid Methyl Ester, identified in lemon grass (C. flexuosus), serves as a standard for quantifying conjugated linoleic acids in thermally stressed olive oil and trans fats in bakery products. [Matreya, LLC. Catalog No. 1255]</p>Fórmula:C19H34O2Cor e Forma:SolidPeso molecular:294.479JW 618
CAS:<p>JW 618 is a selective inhibitor of ABHD6, demonstrating inhibition concentrations (IC50 values) of 38 nM for mouse ABHD6 and 13 nM for rat ABHD6, indicating its potent activity across species [1].</p>Fórmula:C17H14F6N2O2Cor e Forma:SolidPeso molecular:392.3Thioquinapiperifil
CAS:<p>Thioquinapiperifil is a type of phosphodiesterase-5 (PDE-5) inhibitor found in dietary supplements.</p>Fórmula:C24H28N6OSPureza:98%Cor e Forma:SolidPeso molecular:448.58Edaglitazone
CAS:<p>Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.</p>Fórmula:C24H20N2O4S2Pureza:98%Cor e Forma:SolidPeso molecular:464.56Aladotril
CAS:<p>Aladotril is an inhibitor of neutral endopeptidase. Its prodrug is aladotrilat.</p>Fórmula:C21H23NO5SPureza:98%Cor e Forma:SolidPeso molecular:401.48ICMT-IN-9
CAS:<p>ICMT-IN-9 (compound 47) is a potent ICMT inhibitor with an IC50 value of 0.16 μM [1].</p>Fórmula:C22H28FNO2Cor e Forma:SolidPeso molecular:357.46FTI-2153
CAS:FTI-2153 inhibits farnesyltransferase with 1.4 nM IC50, >3000x more effective on H-Ras than Rap1A.Fórmula:C25H30N4O3SCor e Forma:SolidPeso molecular:466.6GNE-783
CAS:<p>GNE-783 is a selective inhibitor of CHK1.</p>Fórmula:C22H20N6Pureza:98%Cor e Forma:SolidPeso molecular:368.43ICMT-IN-17
CAS:<p>ICMT-IN-17 (compound 52) serves as an ICMT inhibitor, exhibiting an IC50 value of 0.38 μM [1].</p>Fórmula:C22H26F3NOCor e Forma:SolidPeso molecular:377.44AZD7687
CAS:<p>AZD7687: Selective DGAT1 inhibitor, IC50 of 80 nM. In vitro reduces postprandial TAG. In vivo significant GI side effects at >5 mg/day dose.</p>Fórmula:C21H25N3O3Cor e Forma:SolidPeso molecular:367.44H-0106 Dihydrochloride
CAS:<p>H-0106 Dihydrochloride is an inhibitor of ROCK that acts by applying strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys.</p>Fórmula:C16H22Cl3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:426.799-OAHSA
CAS:<p>Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of endogenous lipids whose levels are modulated by fasting and high-fat diets and are linked to insulin sensitivity. These compounds typically consist of a C-16 or C-18 fatty acid, such as palmitoleic, palmitic, oleic, or stearic acid, esterified to a hydroxylated C-16 or C-18 lipid. One specific form of FAHFA, known as 9-OAHSA, involves the esterification of oleic acid to 9-hydroxy stearic acid. Within the FAHFA family, OAHSAs notably represent the predominant form found in the serum of glucose-tolerant AG4OX mice, which uniquely overexpress the Glut4 glucose transporter in adipose tissue.</p>Fórmula:C36H68O4Cor e Forma:SolidPeso molecular:564.936N-Desethyl Brinzolamide oxalate
CAS:<p>N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].</p>Fórmula:C12H19N3O9S3Cor e Forma:SolidPeso molecular:445.49IDH1 Inhibitor 2
CAS:<p>IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).</p>Fórmula:C26H22N4OPureza:98%Cor e Forma:SolidPeso molecular:406.48ML395
CAS:<p>ML395 is a potent, selective PLD2 allosteric inhibitor with potent antiviral activity (IC50 =360 nM).</p>Fórmula:C26H29N5O2Pureza:98%Cor e Forma:SolidPeso molecular:443.54KRP-109
CAS:<p>KRP-109, a neutrophil elastase (NE) inhibitor, acts by decreasing expression of TGF-ß Signal Related Genes.</p>Fórmula:C26H30N4O7Pureza:98%Cor e Forma:SolidPeso molecular:510.547RP 70676
CAS:RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).Fórmula:C25H28N4SPureza:99.92%Cor e Forma:SolidPeso molecular:416.58BMS-795311
CAS:<p>Potent CETP inhibitor, boosts HDL-C levels, orally active; IC50=4nM.</p>Fórmula:C33H23F10NO3Cor e Forma:SolidPeso molecular:671.52M-0002
CAS:<p>M-0002, a vasopressin V2 receptor antagonist, is used potentially for the treatment of ascites.</p>Fórmula:C32H29Cl2N3O3Cor e Forma:SolidPeso molecular:574.5Dioleyldimethylammonium chloride
CAS:<p>Dioleyldimethylammonium chloride (DODAC) is a cationic lipid utilized as a transfection reagent [1].</p>Fórmula:C38H76ClNCor e Forma:SolidPeso molecular:582.47ICMT-IN-25
CAS:<p>ICMT-IN-25 (compound 37) serves as a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.025 μM [1].</p>Fórmula:C21H26ClNOCor e Forma:SolidPeso molecular:343.89Entacapone acid
CAS:<p>Entacapone acid (AG 1290) is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).</p>Fórmula:C10H6N2O6Pureza:98.86%Cor e Forma:SolidPeso molecular:250.16FR-234938
CAS:<p>FR-234938 is a non-nucleoside adenosine deaminase inhibitor with anti-inflammatory activity.</p>Fórmula:C19H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:323.39HSD17B13-IN-2
CAS:<p>HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1</p>Fórmula:C21H23F2NO4Cor e Forma:SolidPeso molecular:391.41C16 1-Deoxyceramide (m18:1/16:0)
CAS:<p>C16 1-Deoxyceramide (m18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 1-Deoxyceramide (m18:1/16:0) is 1246298-56-5.</p>Fórmula:C34H67NO2Cor e Forma:SolidPeso molecular:521.9NOX2-IN-2
CAS:<p>NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.</p>Fórmula:C25H25N7O3Cor e Forma:SolidPeso molecular:471.51Amb123203
CAS:<p>Amb123203 is an inhibitor of the budding of mVP40 and eVP40 VLPs that acts by blocking mVP40-795 Nedd4 protein-protein interaction.</p>Fórmula:C25H27N5OSCor e Forma:SolidPeso molecular:445.589(Z),11(Z)-Octadecadienoic acid
CAS:<p>9(Z),11(Z)-Octadecadienoic acid, an isomer of linoleic acid, demonstrates antitumor activity with an EC50 value of 446.1 µM [1].</p>Fórmula:C18H32O2Cor e Forma:SolidPeso molecular:280.45L 670630
CAS:<p>L 670630 is a potent and orally active 5-lipoxygenase inhibitor.</p>Fórmula:C25H26O3Pureza:98%Cor e Forma:SolidPeso molecular:374.47CYP17-IN-1
CAS:<p>CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.</p>Fórmula:C18H17FN2SPureza:99.14% - 99.83%Cor e Forma:SolidPeso molecular:312.4GPX4-IN-2
CAS:<p>GPX4-IN-2 is a potent inhibitor of GPX4, exhibiting antiproliferative activity. It holds potential for cancer research applications.</p>Fórmula:C30H40N2OCor e Forma:SolidPeso molecular:444.651,2-Dipropionyl-sn-glycero-3-PC
CAS:<p>1,2-Dipropionyl-sn-glycero-3-phosphocholine (PC) is a phospholipid characterized by the presence of propionic acid at its sn-1 and sn-2 positions. This compound has applications in the investigation of interactions between water and the phosphocholine headgroup in aqueous solutions.</p>Fórmula:C14H28NO8PCor e Forma:SolidPeso molecular:369.4ICMT-IN-38
CAS:<p>ICMT-IN-38 (Compound 42) is an ICMT inhibitor, demonstrating an IC50 value of 0.049 μM [1].</p>Fórmula:C22H28ClNOCor e Forma:SolidPeso molecular:357.92GGTI-2133
CAS:<p>GGTI-2133: potent GGTase I inhibitor, IC50=38 nM; blocks inflammatory cell invasion in mice asthma.</p>Fórmula:C27H28N4O3Pureza:99.75%Cor e Forma:SolidPeso molecular:456.54A 79175
CAS:<p>A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.</p>Fórmula:C15H13FN2O4Pureza:98%Cor e Forma:SolidPeso molecular:304.27AA 863
CAS:<p>AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.</p>Fórmula:C21H26O5Pureza:98%Cor e Forma:SolidPeso molecular:358.43L-690488
CAS:<p>L-690488 has more effective cell penetration than L-690330. L-690488 is a prodrug of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor.</p>Fórmula:C32H52O16P2Pureza:98%Cor e Forma:SolidPeso molecular:754.695α-Androst-16-en-3-one
CAS:<p>5α-Androst-16-en-3-one, a mammalian pheromone present in boar saliva, plays a crucial role in facilitating social and sexual interactions by acting as a volatile chemical cue. It is utilized to prime sows in estrus for mating or artificial insemination, underscoring its significance in reproductive behavior. Additionally, this compound is detected in human sweat and urine, where it is involved in studies concerning receptor-mediated odorant detection and the genetic foundations of anosmias, thereby broadening its scope of relevance beyond the animal kingdom.</p>Fórmula:C19H28OCor e Forma:SolidPeso molecular:272.432GLUT4 activator 1
CAS:<p>GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM).</p>Fórmula:C23H21FN4O3SPureza:98%Cor e Forma:SolidPeso molecular:452.5ICMT-IN-54
CAS:<p>ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated by</p>Fórmula:C29H45NO3SCor e Forma:SolidPeso molecular:487.74OSMI-2
CAS:<p>OSMI-2 is a cell-permeable inhibitor of O-linked N-acetylglucosamine transferase (OGT).</p>Fórmula:C26H25N3O7S2Pureza:98%Cor e Forma:SolidPeso molecular:555.621-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol
CAS:<p>1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol, a triacylglycerol, features myristic acid, linoleic acid, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. This compound is prevalent in mature human milk, infant formula fats, and butterfat.</p>Fórmula:C53H96O6Cor e Forma:SolidPeso molecular:829.331,2-Dinonadecanoyl-sn-glycero-3-PC
CAS:<p>1,2-Dinonadecanoyl-sn-glycero-3-PC (DNPC), a saturated phospholipid, serves as a standard in quantifying phosphatidylcholines in human synovial fluid and has been utilized in researching lipid bilayer phase transition dynamics.</p>Fórmula:C46H92NO8PCor e Forma:SolidPeso molecular:818.2152-Myristyldipalmitin
CAS:<p>2-Myristyl dipalmitin (PMP), a triglyceride of palmitic acid, shows potential as a lipid marker for Wilson's disease (WD) [1] [2].</p>Fórmula:C49H94O6Cor e Forma:SolidPeso molecular:779.27C2 Dihydro Ceramide (d18:0/2:0)
CAS:<p>C2 Dihydro Ceramide (d18:0/2:0) (C2 Dihydroceramide) is a ceramide that is a precursor of ceramide synthesis and stimulates ABCA1-mediated cholesterol efflux.</p>Fórmula:C20H41NO3Pureza:98%Cor e Forma:SolidPeso molecular:343.54CP-113818
CAS:<p>CP-113818 is a potent inhibitor of cholesterol acyltransferase (ACAT) and can be used to study Alzheimer's disease.</p>Fórmula:C24H42N2OS3Cor e Forma:SolidPeso molecular:470.8BMS-962212
CAS:<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Fórmula:C32H28ClFN8O5Pureza:98%Cor e Forma:SolidPeso molecular:659.07Diflumidone sodium
CAS:<p>Diflumidone sodium is a non-steroidal agent with anti-inflammatory activity.</p>Fórmula:C14H10F2NNaO3SCor e Forma:SolidPeso molecular:333.29Miglustat hydrochloride
CAS:Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I GaucherFórmula:C10H22ClNO4Pureza:99.85%Cor e Forma:SolidPeso molecular:255.74
