Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(271 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(98 produtos)
- Lipídio(58 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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SY-640
CAS:<p>SY-640, an acetamide derivative, strongly protects the liver and lessens Propionibacterium acnes and lipopolysaccharide-induced damage in mice.</p>Fórmula:C11H13NO3Pureza:99.51% - 99.66%Cor e Forma:SolidPeso molecular:207.23(Rac)-sn-Glycerol 3-phosphate sodium
CAS:<p>(Rac)-sn-Glycerol 3-phosphate sodium, an a-site substrate analogue, inhibits indole reactions with E(A-A).</p>Fórmula:C3H7Na2O6PCor e Forma:SolidPeso molecular:216.042,7"-Phloroglucinol-6,6'-bieckol
CAS:<p>2,7"-Phloroglucinol-6,6'-bieckol serves as an effective oral dual α-amylase/α-glucosidase inhibitor, demonstrating IC 50 concentrations of 6.94 μM and 23.35 μM, respectively. This compound is beneficial in mitigating postprandial hyperglycemia among diabetic mice and is applicable in diabetes research [1].</p>Fórmula:C48H30O23Cor e Forma:SolidPeso molecular:974.74hCES2A-IN-2
hCES2A-IN-2 (compound 14n) is an orally active, highly specific, irreversible, covalent inhibitor of hCES2A with an IC50 of 0.04 nM. It targets and covalently binds to the catalytic serine residue (Ser-228) of hCES2A. hCES2A-IN-2 can significantly mitigate irinotecan-induced gastrointestinal toxicity (ITGT) without diminishing the antitumor efficacy of irinotecan in tumor-bearing mice.Cor e Forma:Odour SolidTetrachlorocatechol
CAS:<p>Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol.</p>Fórmula:C6H2Cl4O2Pureza:96.68%Cor e Forma:SolidPeso molecular:247.89FXR antagonist 2
CAS:<p>Compound A-26, a diarylamide FXR blocker, may aid hyperlipidemia and diabetes type 2 research.</p>Fórmula:C22H26Cl2N2O2Cor e Forma:SolidPeso molecular:421.36Cytoglobosin C
CAS:<p>Cytoglobosin C, a derivative of cytochalasan, demonstrates significant cytotoxic effects on SGC-7901 and A549 cell lines, with an inhibitory concentration (IC50</p>Fórmula:C32H38N2O5Cor e Forma:SolidPeso molecular:530.65ACAT-IN-4 hydrochloride
CAS:<p>ACAT-IN-4 hydrochloride is a potent ACAT inhibitor and blocks NF-κB transcription.</p>Fórmula:C32H51ClN2O5SCor e Forma:SolidPeso molecular:611.28Tauro-α-muricholic Acid (sodium salt)
CAS:<p>Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary</p>Fórmula:C26H44NNaO7SCor e Forma:SolidPeso molecular:537.69Alfacalcidol-D6
CAS:<p>Alfacalcidol-D6 is a deuterated Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Fórmula:C27H44O2Pureza:98%Cor e Forma:SolidPeso molecular:406.67Hydroxy ritonavir
CAS:<p>Hydroxy ritonavir, a metabolite of ritonavir, functions as an inhibitor of the HIV protease, thereby serving as a treatment for HIV infection and AIDS [1].</p>Fórmula:C37H48N6O6S2Cor e Forma:SolidPeso molecular:736.94Abz-Ser-Pro-3-nitro-Tyr
CAS:<p>Abz-Ser-Pro-3-nitro-Tyr is the substrate of ACE2 (angiotensin-converting enzyme-2) [1] .</p>Fórmula:C24H27N5O9Cor e Forma:SolidPeso molecular:529.5N1,N12-Diacetylspermine dihydrochloride
CAS:<p>Diacetylspermine 2HCl, a diacetylated Spermine, is a cancer biomarker linked to the disease's up-regulation.</p>Fórmula:C14H32Cl2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:359.34PTP1B-IN-27
<p>PTP1B-IN-27 (Compound 7i) is an inhibitor of protein tyrosine phosphatase 1-B (PTP-1B) with an IC50 of 8.2 µM. Additionally, it inhibits α-glucosidase with an IC50 of 120 µM and exhibits competitive inhibition characteristics (Ki=118 µM).</p>Fórmula:C26H24FN7O2SPeso molecular:517.16962ROR1-IN-2
<p>ROR1-IN-2 (compound 9I) is a potent and selective inhibitor of ROR1. It exhibits antiproliferative activity in various cancer cell lines and significantly inhibits tumor growth in vivo.</p>Fórmula:C30H27N3O4Cor e Forma:SolidPeso molecular:493.200165,6-Dihydroabiraterone
CAS:<p>5,6-Dihydroabiraterone, a metabolite of Abiraterone, is a strong, irreversible CYP17A1 inhibitor, effective in CRPC.</p>Fórmula:C24H33NOCor e Forma:SolidPeso molecular:351.52Lysylcysteine TFA
<p>Lysylcysteine (L-Lysyl-L-cysteine)TFA is a dipeptide composed of lysine and cysteine.</p>Fórmula:C13H21F6N3O7SCor e Forma:SolidPeso molecular:477.10044HIF-1 inhibitor-5
<p>HIF-1 inhibitor-5 (Compound 16e) is a potent inhibitor of HIF-1, exhibiting an IC50 value of 2.38 μM and demonstrating significant anti-angiogenic potential [1</p>Fórmula:C28H35NO5Cor e Forma:SolidPeso molecular:465.58Gluconapin
CAS:<p>Gluconapin serves as a precursor to sulforaphane, an effective anticancer isothiocyanate. It has been found to reduce the increase in plasma triglycerides induced by corn oil consumption in mice.</p>Fórmula:C11H19NO9S2Cor e Forma:SolidPeso molecular:373.4Hydroxypyruvic acid
CAS:<p>Hydroxypyruvic acid: a metabolic intermediate for glycine, serine, threonine; used by serine-pyruvate aminotransferase, glyoxylate reductase.</p>Fórmula:C3H4O4Pureza:98%Cor e Forma:SolidPeso molecular:104.061-(2-Quinoxalinyl)-1,2,3,4-butanetetrol
CAS:1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is a quinoxaline derivative and endogenous metabolite applicable to biochemical experiments and drug synthesis research.Fórmula:C12H14N2O4Pureza:99.49%Cor e Forma:SolidPeso molecular:250.25(S,S)-GSK321
CAS:<p>(S,S)-GSK321 is a (S,S)-enantiomer of GSK321 [1] .</p>Fórmula:C28H28FN5O3Cor e Forma:SolidPeso molecular:501.55Rawsonol
CAS:<p>Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.</p>Fórmula:C29H24Br4O7Cor e Forma:SolidPeso molecular:804.11DMPG sodium
CAS:<p>DMPG sodium is a phospholipid analog commonly used in the preparation of artificial lipid bilayers to mimic the structure and function of biological membranes.</p>Fórmula:C34H66NaO10PPureza:99.05%Cor e Forma:SolidPeso molecular:688.85Impurity B of Calcitriol
CAS:<p>Impurity B is a byproduct of Calcitriol, the active hormone form of vitamin D3 and VDR activator.</p>Fórmula:C27H44O3Pureza:98%Cor e Forma:SolidPeso molecular:416.6413-cis Acitretin D3
CAS:<p>13-cis Acitretin D3, a deuterium-labeled metabolite of Acitretin, is a second-gen systemic retinoid.</p>Fórmula:C21H26O3Pureza:98%Cor e Forma:SolidPeso molecular:329.454Methiocarb
CAS:Methiocarb is a carbamate insecticide acting as a reversible AChE or ChE inhibitor, inducing oxidative stress in rats.Fórmula:C11H15NO2SPureza:98.49%Cor e Forma:Colorless Crystals Immobilizing Agent For Birds Acaricide And Molluscicide (Epa 1998)Peso molecular:225.31N-Fmoc-D-glutamine
CAS:N-Fmoc-D-glutamine is Fmoc-protected alpha-glutamine. Alpha-glutamine is an α-amino acid and the most abundant free amino acid in human blood.Fórmula:C20H20N2O5Pureza:99.14%Peso molecular:368.38Ethyl gentisate
CAS:<p>Ethyl gentisate acts as a dual regulator of cell differentiation, promoting osteoblast differentiation while inhibiting osteoclast differentiation.</p>Fórmula:C9H10O4Pureza:99.55%Cor e Forma:SolidPeso molecular:182.1720,26-Dihydroxyecdysone
CAS:<p>20,26-Dihydroxyecdysone is a predominant ecdysteroid metabolite [1] .</p>Fórmula:C27H44O8Cor e Forma:SolidPeso molecular:496.63BPP
CAS:<p>BPP is a fluorescent microviscosity probe used to image natural HOBr in living cells and zebrafish.</p>Fórmula:C13H13NSCor e Forma:SolidPeso molecular:215.31Kazusamycin A
CAS:<p>Kazusamycin A is a new antitumor antibiotic.</p>Fórmula:C33H48O7Cor e Forma:SolidPeso molecular:556.74Febuxostat impurity 7
CAS:<p>Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H18N2O4SCor e Forma:SolidPeso molecular:334.39Atorvastatin Epoxy Tetrahydrofuran Impurity
CAS:<p>Atorvastatin Epoxy Tetrahydrofuran: an impurity from Atorvastatin oxidation; it's an oral HMG-CoA reductase inhibitor.</p>Fórmula:C26H24FNO5Pureza:98%Cor e Forma:SolidPeso molecular:449.47LysoFos Glycerol 14
CAS:<p>LysoFos Glycerol 14 is a useful organic compound for research related to life sciences. The catalog number is TF0117 and the CAS number is 326495-21-0.</p>Fórmula:C20H40NaO9PCor e Forma:SolidPeso molecular:478.495Febuxostat impurity 6
CAS:<p>Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C18H22N2O4SCor e Forma:SolidPeso molecular:362.44Validamine
CAS:<p>Validamine is a natural pseudo-aminosugar.</p>Fórmula:C7H15NO4Pureza:98%Cor e Forma:White PowderPeso molecular:177.2Octanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Fórmula:C29H49N7NaO17P3SCor e Forma:SolidPeso molecular:915.71Anti-ANGPTL4 Antibody
<p>Anti-ANGPTL4 Antibody is a humanized antibody targeting ANGPTL4.</p>Pureza:99.4% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.4% (SDS-PAGE); 98.4% (SEC-HPLC)Cor e Forma:Odour LiquidD-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
CAS:<p>D-Ribofuranose 1-phosphate is used to synthesize 5-fluorouracil via uridine phosphorylase.</p>Fórmula:C11H24NO8PCor e Forma:SolidPeso molecular:329.28Amiquinsin hydrochloride monohydrate
CAS:<p>Amiquinsin hydrochloride monohydrate is a compound known for its antihypertensive activity. It undergoes metabolism in the body, with its primary metabolite being 4-amino-6,7-dimethoxy-3-quinolineol hydrochloride monohydrate.</p>Fórmula:C11H15ClN2O3Cor e Forma:SolidPeso molecular:258.713,14-dehydro-15-cyclohexyl Carbaprostacyclin
CAS:<p>13,14-dehydro-15-cyclohexyl Carbaprostacyclin, a stable PGI2 analog, impedes ADP-induced platelet aggregation; ED50 ~40 nM in PRP, 77 nM in washed platelets.</p>Fórmula:C21H30O4Cor e Forma:SolidPeso molecular:346.467D-3
CAS:<p>D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent.</p>Fórmula:C48H47N4O10PCor e Forma:SolidPeso molecular:870.896GSK-3β/CK-1δ-IN-1
GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.Fórmula:C22H17F3N4OCor e Forma:SolidPeso molecular:410.39Aspercolorin
CAS:<p>Aspercolorin is a fungal metabolite produced by Aspergillus.</p>Fórmula:C25H28N4O5Cor e Forma:SolidPeso molecular:464.51Mevalonic acid 5-pyrophosphate tetralithium
CAS:<p>Mevalonic acid 5-pyrophosphate (also known as 5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite involved in the mevalonate pathway.</p>Fórmula:C6H10Li4O10P2Cor e Forma:SolidPeso molecular:331.85T-705RMP
CAS:<p>T-705RMP, a T-705 byproduct, mildly inhibits IMPDH in host cells; IC50 = 601 μM.</p>Fórmula:C10H13FN3O9PCor e Forma:SolidPeso molecular:369.20Dimethylaminomicheliolide HCl
CAS:<p>Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate</p>Fórmula:C17H28ClNO3Pureza:99.55%Cor e Forma:SoildPeso molecular:329.86Xanthine oxidase-IN-9
CAS:<p>Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1].</p>Fórmula:C38H50O20Cor e Forma:SolidPeso molecular:826.79Acetoacetic acid
CAS:<p>Acetoacetic acid(3-oxobutanoic acid) is a oxidative stress inducer, gluconeogenesis, and can be used as an indicator of in ketoacidosis.</p>Fórmula:C4H6O3Pureza:99.59% - 99.85%Cor e Forma:SolidPeso molecular:102.09
