Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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SF2312 ammonium
<p>SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under</p>Fórmula:C4H11N2O6PPureza:98%Cor e Forma:SolidPeso molecular:214.11Raloxifene 6,4'-Bis-β-D-glucuronide
CAS:<p>Raloxifene 6,4'-Bis-β-D-glucuronide is a Raloxifene metabolite. Raloxifene is a selective antagonist of estrogen receptor for the prevention of osteoporosis.</p>Fórmula:C40H43NO16SPureza:98%Cor e Forma:SolidPeso molecular:825.83(±)7(8)-EpDPA
CAS:<p>Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina.</p>Fórmula:C22H32O3Cor e Forma:SolidPeso molecular:344.495CP-610431
CAS:<p>CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.</p>Fórmula:C30H37N3O2Cor e Forma:SolidPeso molecular:471.645SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Fórmula:C18H16IN3O3Cor e Forma:SolidPeso molecular:449.243-Oxo-7-hydroxychol-4-enoic acid
CAS:<p>3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.</p>Fórmula:C24H36O4Cor e Forma:SolidPeso molecular:388.54S32826
CAS:<p>S32826, a potent autotaxin inhibitor with an IC50 of 8.8 nM, blocks LPA release and targets α, β, γ isoforms.</p>Fórmula:C21H36NO4PCor e Forma:SolidPeso molecular:397.496(S)-3,4-Dihydroxybutyric acid
CAS:<p>(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.</p>Fórmula:C4H8O4Pureza:98%Cor e Forma:SolidPeso molecular:120.1AH078
<p>AH078 (compound 37) is a selective PROTAC degrader targeting CK1δ and CK1ε with low selectivity for CK1α. AH078 consists of a PROTAC linker (black part) Monomethyl octanoate, a target protein ligand (red part) CK1δ/CK1ε ligand-1, and an E3 ligase ligand (blue part) E3 Ligase Ligand 58. The E3 ligase ligand combined with the linker forms the conjugate E3 Ligase Ligand-linker Conjugate 163.</p>Fórmula:C51H60F2N10O5SCor e Forma:SolidPeso molecular:963.15GLUT1-IN-1
<p>GLUT1-IN-1 inhibits GLUT1; cytotoxic to HeLa, A549, HepG2 (IC50: 5.49, 11.14, 8.73 μM); potential in PDT and cancer research.</p>Fórmula:C25H31BF2I2N6O7Cor e Forma:SolidPeso molecular:830.17Secaubryenol
CAS:<p>Secaubryenol is a 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla.</p>Fórmula:C30H48O3Pureza:98%Cor e Forma:SolidPeso molecular:456.7α-Amylase/α-Glucosidase-IN-6
<p>α-Amylase/α-Glucosidase-IN-6 (compound 5j) serves as a potent dual inhibitor of both α-amylase and α-glucosidase, exhibiting IC50 values of 17.0 µM and 40.1 µM</p>Cor e Forma:Odour SolidCZP-IN-1
<p>CZP-IN-1 (compound SH-1) is an inhibitor targeting the pathogen Trypanosoma cruzi protease (CZP) without affecting cathepsin L (IC50=28 nM). This compound is applicable in Chagas disease research.</p>Fórmula:C20H26N4O4SCor e Forma:SolidPeso molecular:418.51DSM705
CAS:<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Fórmula:C19H19F3N6OCor e Forma:SolidPeso molecular:404.397Tetrahydrothiophen-3-one
CAS:<p>Tetrahydrothiophen-3-one can be used as food spices.</p>Fórmula:C4H6OSPureza:98.67%Cor e Forma:LiquidPeso molecular:102.15DSPE-PEG2000-R8
<p>DSPE-PEG2000-R8 is a PEGylated compound composed of DSPE and the cell-penetrating peptide (R8). It can be applied in drug delivery.</p>Cor e Forma:Odour Solid5α-Hydroxy-6-keto cholesterol
CAS:<p>Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.</p>Fórmula:C27H46O3Cor e Forma:SolidPeso molecular:418.662N-Acetyl-Ser-Asp-Lys-Pro TFA
N-Acetyl-Ser-Asp-Lys-Pro (TFA), a bone marrow tetrapeptide, is a specific ACE substrate for angiotensin conversion.Fórmula:C22H34F3N5O11Pureza:98%Cor e Forma:SolidPeso molecular:601.53BChE-IN-36
<p>hBChE-IN-4 (compound 40) serves as an effective activator for hCA and an inhibitor for BChE. It demonstrates affinity for various hCA subtypes with affinity constants (KA) of 266 nM for hCA I, 76.9 nM for hCA II, 918 nM for hCA IV, 893 nM for hCA VB, and 98.0 nM for hCA VII. Inhibition concentrations (IC50) for eeAChE and eqBChE are recorded at 72.1 nM and 4.2 nM, respectively. hBChE-IN-4 is non-cytotoxic and has demonstrated potential cognitive enhancement effects. It holds potential for research in neurodegenerative and other neuropsychiatric disorders.</p>Cor e Forma:Odour Solid(±)10(11)-EpDPA
CAS:<p>Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.</p>Fórmula:C22H32O3Cor e Forma:SolidPeso molecular:344.495Netupitant metabolite Netupitant N-oxide
CAS:<p>Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.</p>Fórmula:C30H32F6N4O2Pureza:98%Cor e Forma:SolidPeso molecular:594.59Phosphodiesterase
CAS:<p>PDE enzyme hydrolyzes cyclic nucleotides, regulates signal transduction, and varies in type (PDE1-PDE11) with disease research potential.</p>Cor e Forma:SolidTetomilast
CAS:<p>Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive</p>Fórmula:C19H18N2O4SCor e Forma:SolidPeso molecular:370.42Diaphorase
CAS:<p>Diaphorase from anaerobic sludge catalyzes RDX biotransformation via denitrification.</p>Cor e Forma:Solid(±)15-HEDE
CAS:<p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>Fórmula:C20H36O3Cor e Forma:SolidPeso molecular:324.505ML171
CAS:<p>Compound PDK0326, with CAS No. 6631-94-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0326 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C14H11NOSCor e Forma:Mustard-Colored PowderPeso molecular:241.3VDR agonist 2
<p>VDR agonist 2 (compound 16i), a vitamin D receptor (VDR) agonist, effectively inhibits TGF-β1-induced hepatic stellate cell (HSC) activation, demonstrating</p>Fórmula:C20H21F3O3Cor e Forma:SolidPeso molecular:366.37NGR peptide
CAS:<p>Cell-penetrating peptide</p>Fórmula:C20H36N10O8S2Pureza:98%Cor e Forma:SolidPeso molecular:608.692-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Fórmula:C10H14O2Cor e Forma:SolidPeso molecular:166.2219,20-Epoxycytochalasin D
CAS:<p>Fungal metabolite 19,20-Epoxycytochalasin D from Nemania sp. kills P. falciparum; non-toxic to Vero, toxic to BT-549, LLC-PK11, P388 cells.</p>Fórmula:C30H37NO7Cor e Forma:SolidPeso molecular:523.626Impurity C of Alfacalcidol
CAS:<p>Impurity of Alfacalcidol is an impurity of Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Fórmula:C35H49N3O4Pureza:98%Cor e Forma:SolidPeso molecular:575.78Mebeverine acid
CAS:<p>Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.</p>Fórmula:C16H25NO3Pureza:99.66%Cor e Forma:SolidPeso molecular:279.373,3'-Bipyridine
CAS:<p>3,3'-Bipyridine is an inhibitor of CYP2A6, CYP3A4, and CYP2B6, and also inhibits gastric acid secretion in rats.</p>Fórmula:C10H8N2Cor e Forma:SolidPeso molecular:156.18IDO1-IN-12
CAS:<p>IDO1-IN-12 is a potent and orally available IDO1 inhibitor.</p>Fórmula:C21H19F3N2O2Cor e Forma:SolidPeso molecular:388.39Mevinolinic acid
CAS:<p>Mevinolinic acid is an active metabolite of Lovastatin. Lovastatin is an HMG-CoA reductase inhibitor.</p>Fórmula:C24H38O6Pureza:98%Cor e Forma:SolidPeso molecular:422.562(1S)-Calcitriol
CAS:<p>(1S)-Calcitriol, a natural 1α,25(OH)2D3 metabolite, regulates VDR actions like keratinocyte growth inhibition.</p>Fórmula:C27H44O3Cor e Forma:SolidPeso molecular:416.646Butyrolactone II
CAS:<p>Butyrolactone II is a useful organic compound for research related to life sciences. The catalog number is T124034 and the CAS number is 87414-44-6.</p>Fórmula:C19H16O7Cor e Forma:SolidPeso molecular:356.33Ribulose, L-
CAS:<p>Ribulose: key in pentose metabolism, aids L-ribose isomerase study, yeast engineering, and chiral compound research.</p>Fórmula:C5H10O5Cor e Forma:SolidPeso molecular:150.13(S)-3-Thienylglycine
CAS:<p>(S)-3-Thienylglycine is a thiophene derivative and can be used to investigate the genotoxicity of the similar structures with thiophene derivatives.</p>Fórmula:C6H7NO2SPureza:99.68%Cor e Forma:SolidPeso molecular:157.19γ-Glu-Gly TFA
<p>γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid).</p>Cor e Forma:LiquidTrimipramine N-oxide
CAS:<p>Trimipramine N-oxide, a trimipramine metabolite, inhibits hNAT, hSERT, hDAT, and hOCT1/2 with IC50s 11.7-27.4 nM; for depression/anxiety research.</p>Fórmula:C20H26N2OCor e Forma:SolidPeso molecular:310.43Quercetin 3-(6″-caffeoylsophoroside)
CAS:<p>Quercetin 3-(6″-caffeoylsophoroside) is an orally active compound exhibiting α-amylase inhibitory activity, with an IC50 value of 73.66 μg/mL, and demonstrates</p>Fórmula:C27H40N4O7Cor e Forma:SolidPeso molecular:532.63DSPE-PEG3000-R6H4
<p>DSPE-PEG3000-R6H4 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (R6H4). R6H4 is applicable for pH-responsive anticancer drug delivery. DSPE-PEG3000-R6H4 can be utilized for drug delivery purposes.</p>Cor e Forma:Odour SolidRetinyl glucoside
CAS:<p>Retinyl-β-D-glucoside, a biologically active metabolite of vitamin A, naturally occurs in fish and mammals.</p>Fórmula:C26H40O6Pureza:98%Cor e Forma:SolidPeso molecular:448.59trans-2-Hexadecenoyl-L-carnitine
CAS:<p>trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1].</p>Fórmula:C23H43NO4Cor e Forma:SolidPeso molecular:397.59Zaragozic acid D(2)
CAS:<p>Zaragozic acid D(2) inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>Fórmula:C36H50O14Pureza:98%Cor e Forma:SolidPeso molecular:706.77N-Acetyl-α-D-glucosamine 1-phosphate disodium
CAS:<p>N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, plays a crucial role as an intermediate in the biosynthesis of N-linked</p>Fórmula:C8H15NNaO9PCor e Forma:SolidPeso molecular:323.17Monoisobutyl phthalic acid
CAS:<p>Monoisobutyl phthalic acid is a metabolite of phthalate that is in human semen and in meconium.</p>Fórmula:C12H14O4Pureza:98%Cor e Forma:SolidPeso molecular:222.24ALR2-IN-1
CAS:<p>ALR2-IN-1: potent, selective inhibitor of ALR2 (IC50=1.42 μM), antiglycemic, antioxidant; for diabetes research.</p>Fórmula:C16H17N3O2SPureza:98.79%Cor e Forma:SoildPeso molecular:315.39NLG802
CAS:<p>NLG802 is a prodrug of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.</p>Fórmula:C20H30ClN3O3Pureza:99.61%Cor e Forma:SolidPeso molecular:395.92
