Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
GS-493
CAS:<p>GS-493: Specific SHP2 inhibitor, very potent (IC50=71 nM), 29x affinity vs. SHP1, 45x vs. PTP1B; hinders cancer cell growth/movement.</p>Fórmula:C21H14N6O8SCor e Forma:SolidPeso molecular:510.44Echinocandin B
CAS:<p>Echinocandin B: a cyclic hexapeptide from A. nidulans, inhibits fungal cell wall synthesis by blocking beta-1,3-glucan.</p>Fórmula:C52H81N7O16Cor e Forma:SolidPeso molecular:1060.24Octocog alfa
CAS:<p>Octocog alfa, a second-generation, full-length recombinant antihemophilic factor VIII (AHF), is utilized for the treatment of Hemophilia A [1].</p>Cor e Forma:SolidProstaglandin F2β
CAS:<p>Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α.</p>Fórmula:C20H34O5Cor e Forma:White SolidPeso molecular:354.48Axl-IN-16
<p>Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor activity along with receptor</p>Fórmula:C14H19ClO8Pureza:98%Cor e Forma:SolidPeso molecular:350.75BChE-IN-36
<p>hBChE-IN-4 (compound 40) serves as an effective activator for hCA and an inhibitor for BChE. It demonstrates affinity for various hCA subtypes with affinity constants (KA) of 266 nM for hCA I, 76.9 nM for hCA II, 918 nM for hCA IV, 893 nM for hCA VB, and 98.0 nM for hCA VII. Inhibition concentrations (IC50) for eeAChE and eqBChE are recorded at 72.1 nM and 4.2 nM, respectively. hBChE-IN-4 is non-cytotoxic and has demonstrated potential cognitive enhancement effects. It holds potential for research in neurodegenerative and other neuropsychiatric disorders.</p>Cor e Forma:Odour Solid(±)9-HODE cholesteryl ester
CAS:<p>(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.</p>Fórmula:C45H76O3Cor e Forma:SolidPeso molecular:665.1Netupitant metabolite Netupitant N-oxide
CAS:<p>Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.</p>Fórmula:C30H32F6N4O2Pureza:98%Cor e Forma:SolidPeso molecular:594.59PDE5-IN-10
<p>PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM,</p>Fórmula:C21H20N4O2Cor e Forma:SolidPeso molecular:360.41Methiocarb
CAS:<p>Methiocarb is a carbamate insecticide acting as a reversible AChE or ChE inhibitor, inducing oxidative stress in rats.</p>Fórmula:C11H15NO2SPureza:98.49%Cor e Forma:Colorless Crystals Immobilizing Agent For Birds Acaricide And Molluscicide (Epa 1998)Peso molecular:225.31Malate dehydrogenase
CAS:<p>Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .</p>Cor e Forma:SolidMK-8262
CAS:<p>MK-8262: oral CETP inhibitor, potent (IC50 = 53 nM, log D = 5.3), may impact HDL/LDL and CHD research.</p>Fórmula:C35H25F9N2O5Cor e Forma:SolidPeso molecular:724.58MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Fórmula:C26H21F6N2O5Cor e Forma:SolidPeso molecular:555.45VDR agonist 2
<p>VDR agonist 2 (compound 16i), a vitamin D receptor (VDR) agonist, effectively inhibits TGF-β1-induced hepatic stellate cell (HSC) activation, demonstrating</p>Fórmula:C20H21F3O3Cor e Forma:SolidPeso molecular:366.37PROTAC CYP1B1 degrader-1
CAS:<p>Compound 6C, a PROTAC degrader, targets CYP1B1 with IC50s (95.1 nM CYP1B1, 9838.6 nM CYP1A2) for prostate cancer research.</p>Fórmula:C43H39N5O10Cor e Forma:SolidPeso molecular:785.82-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Fórmula:C10H14O2Cor e Forma:SolidPeso molecular:166.22AMG-529
<p>AMG-529 is a humanized monoclonal antibody targeting ASGR1, capable of binding to ASGR1 and inhibiting ligand attachment, which subsequently results in an increase in ALP (ASGR1-inhibited biomarker) levels.</p>Cor e Forma:Odour LiquidTetrachlorocatechol
CAS:<p>Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol.</p>Fórmula:C6H2Cl4O2Pureza:96.68%Cor e Forma:SolidPeso molecular:247.89Secaubryenol
CAS:<p>Secaubryenol is a 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla.</p>Fórmula:C30H48O3Pureza:98%Cor e Forma:SolidPeso molecular:456.7Adenosine 5'-succinate
CAS:<p>Adenosine 5'-succinate, similar to AMP, inhibits taste receptors activated by Denatonium.</p>Fórmula:C14H17N5O7Cor e Forma:SolidPeso molecular:367.318Streptolysin O
CAS:<p>Streptolysin O: lyses cells, cardiotoxic, used for cell permeabilization, has active and inactive states.</p>Pureza:98%Cor e Forma:Solid1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol
CAS:<p>Triacylglycerol with palmitic, oleic, arachidonic acids at sn-1, sn-2, sn-3; found in rat retina lipid extracts.</p>Fórmula:C57H100O6Cor e Forma:SolidPeso molecular:881.421(1S)-Calcitriol
CAS:<p>(1S)-Calcitriol, a natural 1α,25(OH)2D3 metabolite, regulates VDR actions like keratinocyte growth inhibition.</p>Fórmula:C27H44O3Cor e Forma:SolidPeso molecular:416.6467-Hydroxymethotrexate
CAS:<p>7-Hydroxymethotrexate, major Methotrexate metabolite, inhibits dihydrofolate reductase and DNA synthesis by blocking folic acid conversion.</p>Fórmula:C20H22N8O6Pureza:99.72%Cor e Forma:SolidPeso molecular:470.44Ribulose, L-
CAS:<p>Ribulose: key in pentose metabolism, aids L-ribose isomerase study, yeast engineering, and chiral compound research.</p>Fórmula:C5H10O5Cor e Forma:SolidPeso molecular:150.13Venetoclax N-oxide
CAS:<p>Venetoclax N-oxide is a byproduct of potent, oral Bcl-2 inhibitor Venetoclax (ABT-199/GDC-0199) with Ki <0.01 nM.</p>Fórmula:C45H50ClN7O8SCor e Forma:SolidPeso molecular:884.44Phosphoramidon
CAS:<p>Phosphoramidon inhibits metallo-endopeptidase, endothelin-converting enzyme, and thermolysin; derived from Streptomyces tanashiensis culture.</p>Fórmula:C23H34N3O10PPureza:98%Cor e Forma:SolidPeso molecular:543.5Trimipramine N-oxide
CAS:<p>Trimipramine N-oxide, a trimipramine metabolite, inhibits hNAT, hSERT, hDAT, and hOCT1/2 with IC50s 11.7-27.4 nM; for depression/anxiety research.</p>Fórmula:C20H26N2OCor e Forma:SolidPeso molecular:310.43Diadenosine pentaphosphate pentasodium
CAS:<p>Diadenosine pentaphosphate pentasodium, an endogenous purine from platelets and various cells, has vasoactive properties.</p>Fórmula:C20H24N10Na5O22P5Cor e Forma:SolidPeso molecular:1026.28DSPE-PEG3000-R6H4
<p>DSPE-PEG3000-R6H4 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (R6H4). R6H4 is applicable for pH-responsive anticancer drug delivery. DSPE-PEG3000-R6H4 can be utilized for drug delivery purposes.</p>Cor e Forma:Odour SolidCaffeoylcalleryanin
CAS:<p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>Fórmula:C22H24O11Cor e Forma:SolidPeso molecular:464.4trans-2-Hexadecenoyl-L-carnitine
CAS:<p>trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1].</p>Fórmula:C23H43NO4Cor e Forma:SolidPeso molecular:397.59H-Gly-Pro-Gly-NH2
CAS:<p>H-Gly-Pro-Gly-NH2, a tripeptide, inhibits HIV-1 and HIV-2 replication (EC50: 35µM, 30µM) by blocking capsid formation.</p>Fórmula:C9H16N4O3Cor e Forma:SolidPeso molecular:228.25Geranylgeranyl pyrophosphate
CAS:<p>Geranylgeranyl pyrophosphate: a metabolite for protein modification and diterpenoid precursor, used in cancer research.</p>Fórmula:C20H36O7P2Cor e Forma:SolidPeso molecular:450.44Penicitide A
CAS:<p>Penicitide A: marine metabolite, moderately cytotoxic to A. brassicae, HepG2 cells.</p>Fórmula:C18H34O4Cor e Forma:SolidPeso molecular:314.46Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)
CAS:<p>Vildagliptin's main human metabolite inhibits DPP-4 (IC50: 477 μM) in Caco-2 cells, formed by cyano group hydrolysis.</p>Fórmula:C19H27F3N2O6Cor e Forma:SolidPeso molecular:436.428Methylcardol triene
CAS:<p>Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.496NCGC00092410
CAS:<p>NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM.</p>Fórmula:C21H27N3O2Pureza:98.68%Cor e Forma:SolidPeso molecular:353.46DSPE-PEG1000-RVG29
<p>DSPE-PEG1000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 can specifically bind to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and cross the BBB.</p>Cor e Forma:Odour Solid2-Ethylnaphthalene
CAS:<p>2-Ethylnaphthalene exhibits inhibitory activity against CYP1A2, CYP2A5, and CYP2A6 and can be used in biochemical experiments and drug synthesis.</p>Fórmula:C12H12Cor e Forma:SolidPeso molecular:156.22D-Erythrose 4-phosphate sodium
CAS:<p>D-erythrose 4-sodium phosphate: sodium salt of monosaccharide, made from erythritol via 3 isomerases.</p>Fórmula:C4H8NaO7PPureza:98%Cor e Forma:SolidPeso molecular:222.07IDO1/TDO-IN-7
<p>IDO1/TDO-IN-7 (Compound 43b), an isochinoline derivative, functions as a potent dual inhibitor of IDO1/TDO with IC50 values of 0.31 μM and 0.08 μM, respectively. Demonstrating favorable pharmacokinetics and strong antitumor efficacy in the B16-F10 tumor model, this compound also exhibits low toxicity.</p>Cor e Forma:Odour SolidWH-15
CAS:<p>WH-15: fluorogenic reporter for PLC-γ1, PLC-δ1, PLC-β2 with Km values of 49; 30, 86.1 µM. Cleaves to fluorescent 6-aminoquinoline for live cell imaging.</p>Fórmula:C31H43N2O18P3Cor e Forma:SolidPeso molecular:824.6Anti-osteoporosis agent-10
<p>Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.</p>Cor e Forma:Odour Solidβ-Tetralone
CAS:<p>β-Tetralone (2-Tetralone) is a vital drug synthesis precursor with complex pharmacological properties in combating neurological disorders. Cost-effective and quality-assured.</p>Fórmula:C10H10OPureza:97.26% - 99.18%Cor e Forma:Clear To Yellow LiquidPeso molecular:146.19(-)-Jasmonoyl-L-isoleucine
CAS:<p>(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile), an enantiomer of (+)-JA-L-Ile [1], is an inactive endogenous hormone.</p>Fórmula:C18H29NO4Cor e Forma:SolidPeso molecular:323.43PROTAC MAGL degrader-1
<p>PROTACMAGLdegrader-1 is an orally active PROTAC agent that simultaneously targets both monoacylglycerol lipase (MAGL) and the E3 ubiquitin ligase MDM2. It functions by degrading MAGL and inhibiting the interaction between MDM2 and p53. Additionally, PROTACMAGLdegrader-1 has partial blood-brain barrier (BBB) penetration and can induce apoptosis in glioblastoma stem cells (GSC).</p>Cor e Forma:Odour SolidPhoto-DL-lysine
<p>Photo-DL-lysine is a photo-reactive amino acid based on DL-lysine used to capture proteins that are post-translationally modified by lysine binding.</p>Fórmula:C6H12N4O2Peso molecular:172.096032-Chlorophenylboronic acid
CAS:<p>2-Chlorophenylboronic acid: A monohalogenated phenylboronic acid used in drug synthesis and as a fatty acid amidase inhibitor.</p>Fórmula:C6H6BClO2Pureza:99.42%Cor e Forma:SolidPeso molecular:156.37T3 Acyl glucuronide
CAS:<p>T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite</p>Fórmula:C21H20I3NO10Pureza:98%Cor e Forma:SolidPeso molecular:827.1
