Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8625 produtos de "Metabolismo"
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α-Glucosidase-IN-60
<p>α-Glucosidase-IN-60 (Compound 5k) acts as a competitive inhibitor of α-Glucosidase, with an IC50 of 10.8 μM.</p>Fórmula:C23H14N2O5Peso molecular:398.09027SGK1-IN-3 hydrochloride
<p>SGK1-IN-3 hydrochloride (compound 3a) is an efficacious, orally bioavailable SGK1 inhibitor. The serine/threonine kinase SGK1 acts as an activator of the β-catenin pathway and strongly stimulates cartilage degradation, being upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 hydrochloride holds potential for osteoarthritis research.</p>Fórmula:C23H21Cl3N6O3SPeso molecular:566.04614Porfimer Sodium
CAS:<p>Porfimer sodium, a sodium salt with photodynamic properties, targets tumor cells and induces cytotoxicity with 630 nm laser activation.</p>Fórmula:C68H74N8O11Cor e Forma:SolidPeso molecular:1179.385Nattokinase
CAS:<p>Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.</p>Cor e Forma:Solid2-(Isopentylamino)naphthalene-1,4-dione
CAS:<p>2-(Isopentylamino)naphthalene-1,4-dione: a vitamin K analog inhibiting spasms and seizures in mice with various ED50 values.</p>Fórmula:C15H17NO2Cor e Forma:SolidPeso molecular:243.306Conagenin
CAS:<p>Conagenin is a small molecular immunomodulator isolated by Streptomyces roseosporus.</p>Fórmula:C10H19NO6Pureza:98%Cor e Forma:SolidPeso molecular:249.26Etodolac Acyl Glucuronide
CAS:<p>Etodolac acyl glucuronide is an NSAID metabolite formed by UGT1A9, UGT1A10, and UGT2B7 glucuronidation.</p>Fórmula:C23H29NO9Cor e Forma:SolidPeso molecular:463.483Methylbenzethonium chloride hydrate
CAS:<p>Methylbenzethonium chloride hydrate exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. Additionally, it is utilized as a preservative in cosmetics and pharmaceutical formulations to inhibit microbial growth.</p>Fórmula:C28H46ClNO3Cor e Forma:SolidPeso molecular:480.12Propionylcarnitine
CAS:<p>Propionylcarnitine (Propionyl carnitine) is a widely used dietary supplement that has been associated with glaucoma and does it ruptu</p>Fórmula:C10H19NO4Pureza:99.69%Cor e Forma:SolidPeso molecular:217.26(R)-SCH 42495
CAS:<p>(R)-SCH 42495, less potent enantiomer of NEP inhibitor SCH 42495, has oral antihypertensive action.</p>Fórmula:C20H29NO4S2Pureza:98%Cor e Forma:SolidPeso molecular:411.58MCI-INI-3
CAS:<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Fórmula:C21H15N3O4Cor e Forma:SolidPeso molecular:373.365,7-Dichloropyrazolo[1,5-a]pyrimidine
CAS:<p>5,7-Dichloropyrazolo[1,5-a]pyrimidine (fragment 5) is an inhibitor of the enzyme phosphodiesterase 10A (PDE10A) with a Ki value of 24 μM. This compound can be employed in research related to schizophrenia.</p>Fórmula:C6H3Cl2N3Cor e Forma:SolidPeso molecular:188.01isomer-GAT 107
CAS:<p>isomer-GAT 107 ((-)GAT 107) is an inactive isomer of (+)GAT 107.</p>Fórmula:C18H17BrN2O2SPureza:99.33%Cor e Forma:SoildPeso molecular:405.31Ninopterin
CAS:<p>Ninopterin is an experimental antineoplastic and folic acid analog.</p>Fórmula:C20H21N7O6Pureza:98%Cor e Forma:SolidPeso molecular:455.42Triethyl phosphate
CAS:<p>Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".</p>Fórmula:C6H15O4PPureza:98%Cor e Forma:Clear LiquidPeso molecular:182.162,3,4,6,7,8-Hexachlorodibenzofuran
CAS:<p>2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It induces the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-o-deethylase (EROD) genes in H-4-II-E rat hepatoma cells, with EC50 values of 0.687 and 0.575 nM, respectively.</p>Fórmula:C12H2Cl6OCor e Forma:SolidPeso molecular:374.86Osmanthuside H
CAS:<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Fórmula:C19H28O11Cor e Forma:SolidPeso molecular:432.422Leucomyosuppressin
CAS:<p>Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.</p>Fórmula:C59H84N16O15Pureza:98%Cor e Forma:SolidPeso molecular:1257.418Tetrahydropteroylpentaglutamate
CAS:<p>H4PteGlu5 strongly inhibits itself and tightly binds in vivo, almost irreversibly, as a coenzyme.</p>Fórmula:C39H51N11O18Pureza:98%Cor e Forma:SolidPeso molecular:961.894,8-Dioxa-3H-perfluorononanoic acid
CAS:<p>4,8-Dioxa-3H-perfluorononanoic acid, a type of per- and polyfluoroalkyl substance (PFAS), exhibits affinity for the human pregnane X receptor (hPXR) and demonstrates potential agonistic activity.</p>Fórmula:C7H2F12O4Cor e Forma:SolidPeso molecular:378.07Acanthifolicin
CAS:<p>Acanthifolicin, an okadaic acid derivative, has been shown top inhibit protein phosphatase 1 with an IC50= 20 nM (similar to that of okadaic acid at 19 nM).</p>Fórmula:C44H68O13SCor e Forma:SolidPeso molecular:837.08Folitixorin calcium
CAS:<p>Folitixorin calcium is an antineoplastic enhancing agent.</p>Fórmula:C20H25CaN7O6Cor e Forma:SolidPeso molecular:499.541SLC7A11-IN-3
<p>SLC7A11-IN-3 (Compound 42711_11) acts as an inhibitor of SLC7A11.</p>Cor e Forma:Odour SolidEvinacumab
CAS:<p>Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.</p>Pureza:100% (SEC-HPLC) - 99.43% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.5 kDaAZD-3199 free base
CAS:<p>AZD-3199, a β2 adrenergic receptor agonist, is used potentially for the treatment of asthma and chronic obstructive.</p>Fórmula:C32H42N4O4SCor e Forma:SolidPeso molecular:578.77Kahalalide A
CAS:<p>Kahalalide A has antimycobacterial activity isolated from the mollusk Elysia rufescens.</p>Fórmula:C46H67N7O11Pureza:98%Cor e Forma:SolidPeso molecular:894.082,3-Dehydrosilybin B
CAS:<p>2,3-Dehydrosilybin B is a useful organic compound for research related to life sciences and the catalog number is T125883.</p>Fórmula:C25H20O10Cor e Forma:SolidPeso molecular:480.42DSPE-PEG5000-pPB
<p>DSPE-PEG5000-pPB is a PEG compound composed of DSPE and the cyclic oligopeptide (pPB). The pPB component has high binding affinity to PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB is applicable for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG1000-TAASGVRSMH
<p>DSPE-PEG1000-TAASGVRSMH is a PEG compound composed of DSPE and TAASGVRSMH. The TAASGVRSMH sequence exhibits high affinity for the NG2 proteoglycan on PC membranes. DSPE-PEG1000-TAASGVRSMH is useful for drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG1000-VIP
<p>DSPE-PEG1000-VIP is a PEG compound composed of DSPE and the vasoactive intestinal peptide (VIP). It can be utilized for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG5000-PP1
<p>DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the PP1 peptide, which targets inflammatory atherosclerotic plaques. It can be used for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG2000-VIP
<p>DSPE-PEG2000-VIP is a PEG-based compound composed of DSPE and the vasoactive intestinal peptide (VIP). This compound is useful for drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG1000-CSTSMLKAC
<p>DSPE-PEG1000-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. The CSTSMLKAC component facilitates phage-mediated targeting to ischemic cardiac tissue. DSPE-PEG1000-CSTSMLKAC is applicable in drug delivery.</p>Cor e Forma:Odour SolidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Fórmula:C14H26Cl2N6O5Cor e Forma:SolidPeso molecular:428.13417Equilenin
CAS:<p>Equilenin (E 400) is a natural estrogen that is an endocrine disruptor and has been used in breast cancer research.</p>Fórmula:C18H18O2Pureza:99.4%Cor e Forma:SolidPeso molecular:266.33(24S)-24,25-Dihydroxyvitamin D3
CAS:<p>(24S)-24,25-Dihydroxyvitamin D3 undergoes various levels of hydroxylation to form active vitamin D3 analogs.</p>Fórmula:C27H44O3Pureza:98.98%Cor e Forma:SolidPeso molecular:416.64PPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Fórmula:C23H28FN7O3Cor e Forma:SolidPeso molecular:469.51C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
CAS:<p>C-Type Natriuretic Peptide (1-53), from porcine, rat, and mouse sources, serves as an activator of particulate guanylate cyclase B (pGC-B), prominently found in endothelial cells, kidneys, and the heart. This peptide efficiently mediates a potent anti-fibrotic effect in human cardiac and renal fibroblasts through the production of the second messenger cGMP.</p>Cor e Forma:SolidNAD Synthetase
CAS:<p>NAD Synthetase is responsible for the final step in the synthesis of Nicotinamide Adenine Dinucleotide (NAD). The enzyme sourced from Escherichia coli exhibits Km values of 200 μM for NAD, 11 μM for ATP, and 0.65 μM for ammonia. Conversely, NAD Synthetase derived from yeast demonstrates Km values of 170 μM for NAD, 190 μM for ATP, and 64 μM for ammonia. This enzyme is applicable in enzymatic assays for ATP, ammonia, urea, or creatinine and can also be used in enzymatic recycling methods. Additionally, NAD Synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative disorders.</p>Cor e Forma:SolidESI1
<p>ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.</p>Fórmula:C18H18ClN5OCor e Forma:SolidPeso molecular:355.82Galactose 1-dehydrogenase
<p>Galactose 1-dehydrogenase, pseudomonas fluorescens, a dehydrogenase found in Pseudomonas fluorescens, facilitates the oxidation of L-arabinose and D-galactose, utilizing NADP+/NAD+ as a cofactor. This enzyme is employed in diagnostic assays to quantify total galactose levels and serves as a biocatalyst in the production of galacturonic acid salts.</p>Cor e Forma:Odour SolidMethyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate
CAS:<p>Compound 7a, Methyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate, is a metabolite of bile acid.</p>Fórmula:C25H40O4Cor e Forma:SolidPeso molecular:404.58D-Ribose 5-phosphate disodium dihydrate
CAS:<p>D-Ribose 5-phosphate disodium dihydrate is a key intermediate and end product in both PPP branches, vital for nucleotide and nucleic acid synthesis.</p>Fórmula:C5H13Na2O10PPureza:99% - 99%Cor e Forma:SolidPeso molecular:310.1Acetoacetic acid
CAS:<p>Acetoacetic acid(3-oxobutanoic acid) is a oxidative stress inducer, gluconeogenesis, and can be used as an indicator of in ketoacidosis.</p>Fórmula:C4H6O3Pureza:99.59% - 99.85%Cor e Forma:SolidPeso molecular:102.09WAY-311610
CAS:<p>WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.</p>Fórmula:C16H13F3N4O2Pureza:98.01%Cor e Forma:SolidPeso molecular:350.3GW6340
CAS:<p>GW6340 is a selective LXR agonist with potential anticancer activity that promotes macrophage reverse cholesterol transport (mRCT) and can be used to study atherosclerosis.</p>Fórmula:C33H32ClF3N2O2Pureza:99.79%Cor e Forma:SoildPeso molecular:581.07(S)-O-Desmethyl Venlafaxine N-Oxide
CAS:<p>(S)-O-Desmethyl Venlafaxine N-Oxide is the N-oxide metabolite of Venlafaxine, an SNRI antidepressant.</p>Fórmula:C16H25NO3Cor e Forma:SolidPeso molecular:279.37IFB-088 acetate
CAS:<p>IFB-088 acetate targets PPP1R15A-related diseases, including cancers and protein misfolding disorders.</p>Fórmula:C10H13ClN4O2Pureza:90%Cor e Forma:SolidPeso molecular:256.69ONO-8430506
CAS:<p>ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.</p>Fórmula:C27H28FN3O3Pureza:98.34%Cor e Forma:SolidPeso molecular:461.53Endo-1,3-β-glucanase
CAS:<p>Endo-1,3-β-glucanase (Lyticase) is a glucanase from fungi and Chlamydomonas reinhardtii that displays lytic activity on fungal cells.</p>Cor e Forma:Solid
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