Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8625 produtos de "Metabolismo"
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Zabicipril HCl
CAS:<p>Zabicipril HCl（S 9650） is a potent angiotensin-converting enzyme inhibitor.</p>Fórmula:C23H33ClN2O5Pureza:99.66%Cor e Forma:SoildPeso molecular:452.97DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Fórmula:C17H12ClF6N5O2Cor e Forma:SolidPeso molecular:467.753DSPE-PEG2000-CGKRK
<p>DSPE-PEG2000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is suitable for use in drug delivery.</p>Cor e Forma:Odour Solid16(S)-HETE
CAS:<p>16(S)-HETE, a CYP450 byproduct of arachidonic acid, inhibits kidney tubule ATPase by 60% at 2 μM upon angiotensin II trigger.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.473α-Amyrone
CAS:<p>Alpha-Amyrone (Alfa-Amyrenone) is a natural poduct found in aerial parts of Inula candida (L.) Cass. subsp. Alpha-Amyrone is an antineoplastic agent.</p>Fórmula:C30H48OPureza:99.86%Cor e Forma:SolidPeso molecular:424.7Sarcinapterin
CAS:<p>Sarcinapterin is a coenzyme isolated from Methanosarcina barkeri.</p>Fórmula:C35H48N7O19PCor e Forma:SolidPeso molecular:901.773hCA/VEGFR-2-IN-3
<p>hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.</p>Fórmula:C24H28N6O6SPureza:98%Cor e Forma:SolidPeso molecular:528.58Myxochelin A
CAS:<p>Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.</p>Fórmula:C20H24N2O7Cor e Forma:SolidPeso molecular:404.419Kijanimicin
CAS:<p>Kijanimicin: antitumor, antibiotic with unique activity against Gram-positive, anaerobic bacteria, and malaria.</p>Fórmula:C67H100N2O24Cor e Forma:SolidPeso molecular:1317.527SR-29065
<p>SR-29065 is a selective agonist of REV-ERBα, utilized in the research of autoimmune disorders [1].</p>Cor e Forma:Odour SolidCRCD2
CAS:<p>1H-Benzimidazole-6-carboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-可能具有抗肿瘤活性。</p>Fórmula:C17H16N4O2SPureza:99.52%Cor e Forma:SoildPeso molecular:340.44-hydroxy Nonenal Mercapturic Acid
CAS:<p>Peroxidation of ω-6 PUFAs produces 4-HNE, which is rapidly cleared and excreted, mostly as urine metabolites, within 48h in rats.</p>Fórmula:C14H25NO5SCor e Forma:SolidPeso molecular:319.42Geranyl pyrophosphate triammonium
CAS:<p>Geranyl pyrophosphate, an intermediary for making cholesterol, terpenes, and others, forms from dimethylallyl and isopentenyl pyrophosphates.</p>Fórmula:C10H29N3O7P2Cor e Forma:SolidPeso molecular:365.304MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Fórmula:C26H21F6N2NaO5Cor e Forma:SolidPeso molecular:578.44IGUANA-1
CAS:<p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>Fórmula:C27H26ClN3O4Pureza:99.08%Cor e Forma:SolidPeso molecular:491.97(-)-Dihydroguaiaretic acid
<p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>Fórmula:C20H26O4Cor e Forma:SolidPeso molecular:330.424AMK318
AMK318 (Immobilized cephalexin acylase) is a biocatalyst and a critical enzyme in novel biocatalyst technology. Enzyme engineering focuses on improving enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions (such as low or high pH). By incorporating stimulus responsiveness into these enzyme modifications, dynamic control of activity becomes feasible.VU534
CAS:<p>VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related</p>Fórmula:C21H22FN3O3S2Pureza:98.85%Cor e Forma:SolidPeso molecular:447.55PKM2-IN-4
<p>Compound 5C, referred to as Pkm2-in-4, is a selective PKM2 inhibitor (IC50 = 0.35 µM) that modulates pyruvate-dependent respiration and promotes mitochondrial</p>Fórmula:C15H17BrClNO3SeCor e Forma:SolidPeso molecular:453.62DSPE-PEG5000-CGKRK
<p>DSPE-PEG5000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is utilized for drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG5000-K237
<p>DSPE-PEG5000-K237 is a PEG compound composed of DSPE and the KDR-targeting peptide (K237). K237 effectively disrupts the interaction between VEGF and KDR receptors, yielding significant biological effects, such as inhibiting angiogenesis and tumor growth. DSPE-PEG5000-K237 is applicable for drug delivery.</p>Cor e Forma:Odour SolidTheodrenaline hydrochloride
CAS:<p>Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.</p>Fórmula:C17H22ClN5O5Pureza:98% - 98.18%Cor e Forma:SoildPeso molecular:411.842,8-Dihydroxyadenine
CAS:<p>2,8-Dihydroxyadenine causes urinary crystals, kidney stones, and helps diagnose APRT deficiency.</p>Fórmula:C5H5N5O2Cor e Forma:SolidPeso molecular:167.128Lysinoalanine
CAS:<p>Lysinoalanine is an unusual amino acid, not a dipeptide, which exists in proteins of cooked foods. It is formed in food that is heated or treated with alkali.</p>Fórmula:C9H19N3O4Cor e Forma:SolidPeso molecular:233.26Antiproliferative agent-12
<p>Antiproliferative agent-10, a ruthenium(II) complex, inhibits cancer by blocking mitochondrial calcium uptake.</p>Fórmula:C46H40Cl2N6P2RuCor e Forma:SolidPeso molecular:910.79Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Fórmula:C13H16FeN2O2Cor e Forma:SolidPeso molecular:288.12Estriol 3-glucuronide
CAS:<p>Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2].</p>Fórmula:C24H32O9Cor e Forma:SolidPeso molecular:464.511Tetrahydrothiophen-3-one
CAS:<p>Tetrahydrothiophen-3-one can be used as food spices.</p>Fórmula:C4H6OSPureza:98.67%Cor e Forma:LiquidPeso molecular:102.15Tajixanthone
CAS:<p>Tajixanthone is the fungus metabolite from Aspergillus variecolor [1] .</p>Fórmula:C25H26O6Cor e Forma:SolidPeso molecular:422.47MS1262-C3-amide-C10-amine
<p>MS1262-C3-amide-C10-amine is an E3 Ligase Ligand-Linker conjugate. It includes a GLP ligand targeting the E3 ligase SPOP and a PROTAC linker. This compound can be utilized in designing PROTACs such as example [MS479].</p>Cor e Forma:Odour SolidCA Ⅱ-IN-1
<p>CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.</p>Fórmula:C18H19NO6SCor e Forma:SolidPeso molecular:377.41Rostratin C
CAS:<p>Rostratin C, a cytotoxic disulfide, exhibits in vitro cytotoxicity against human colon carcinoma (HCT-116), demonstrating an IC50 value of 0.76 μg/mL.</p>Fórmula:C20H24N2O8S2Cor e Forma:SolidPeso molecular:484.54Galactosylhydroxylysine
CAS:<p>Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.</p>Fórmula:C12H24N2O8Cor e Forma:SolidPeso molecular:324.33Cy3-PEG-DSPE (MW 5000)
<p>Cy3-PEG-DSPE (MW 5000) is a fluorescent PEG phospholipid that incorporates Cy3 dye and is utilized for protein/nucleic acid labeling. It can self-assemble into micelles or lipid bilayers in aqueous solutions and is employed in the preparation of liposomes or nanoparticles for the delivery of substances such as mRNA or DNA vaccines.</p>Cor e Forma:SolidPeso molecular:5000 (Average)N-Desethyl Bimatoprost
CAS:<p>N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide.</p>Fórmula:C23H33NO4Cor e Forma:SolidPeso molecular:387.516-Azathymine acid
CAS:<p>6-Azathymine is a metabolite of Pymetrozine, an insecticide targeting aphids and whiteflies by disrupting feeding.</p>Fórmula:C4H3N3O4Cor e Forma:SolidPeso molecular:157.08DSPE-PEG5000-RVG29
<p>DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.</p>Cor e Forma:Odour Solidα-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid
CAS:<p>α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid was identified as possible dual inhibitors for hLTA4H and hLTC4S enzymes by the computer-aided</p>Fórmula:C23H23NO3Pureza:97.19% - 99.36%Cor e Forma:SoildPeso molecular:361.43Nε,Nε,Nε-Trimethyllysine chloride
CAS:<p>Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine and a component of histone proteins.</p>Fórmula:C9H21ClN2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:224.73Sofosbuvir impurity C
CAS:<p>Sofosbuvir impurity C, a less active byproduct, inhibits HCV RNA replication and exhibits strong anti-HCV effects.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45Adefovir diphosphate 2TEA
<p>Adefovir diphosphate 2TEA,a metabolite of Adefovir, an oral reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and HIV.</p>Fórmula:C20H43N7O7P2Pureza:98.33%Cor e Forma:SolidPeso molecular:555.55Tpp-CAQK
<p>Tpp-CAQK, a specially engineered mitochondrial compound, has been shown to improve phagocytosis of myelin debris by macrophages, reduce mitochondrial dysfunction and pro-inflammatory features, and enhance tissue repair and functional recovery in mice after spinal cord injury.</p>Fórmula:C40H54BrN6O7PSCor e Forma:SolidPeso molecular:873.84Sofosbuvir impurity E
<p>Sofosbuvir impurity E, a less active byproduct, inhibits HCV RNA replication with potent anti-HCV effects.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45DSPE-PEG1000-ANG
<p>DSPE-PEG1000-ANG is a PEG compound composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG demonstrates high LRP1 binding efficiency and has been utilized for targeting glioma delivery. DSPE-PEG1000-ANG is suitable for drug delivery applications.</p>Cor e Forma:Odour SolidSKI2852
CAS:<p>SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.</p>Fórmula:C27H34FN5O4SPureza:99.89%Cor e Forma:SolidPeso molecular:543.65Enpp-1-IN-15
CAS:<p>Compound 88a (Enpp-1-IN-15) is an inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (Enpp-1), exhibiting a Ki value of 0.00586 nM [1].</p>Fórmula:C16H20N6O2SCor e Forma:SolidPeso molecular:360.43A 58365 A
CAS:<p>A 58365 A, an ACE inhibitor from Streptomyces chromofuscus, treats heart failure and hypertension.</p>Fórmula:C12H13NO6Cor e Forma:SolidPeso molecular:267.23Dapagliflozin-3-O-β-D-Glucuronide
CAS:<p>Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin .</p>Fórmula:C27H33ClO12Cor e Forma:SolidPeso molecular:585ω-Conotoxin CVIA
CAS:<p>ω-Conotoxin CVIA, a 27-amino acid neuropeptide, functions as a blocker of voltage-sensitive calcium channels (VSCCs) [1].</p>Fórmula:C97H161N39O36S6Pureza:98%Cor e Forma:SolidPeso molecular:2641.955(S)-HETE
CAS:<p>5(S)-HETE, an endogenous metabolite found in the blood, is utilized in researching Rheumatoid Arthritis, Rhinitis, and Asthma [1] [2].</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.47
