Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8595 produtos de "Metabolismo"
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α-Pyrone
CAS:<p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>Fórmula:C5H4O2Cor e Forma:SolidPeso molecular:96.08Antiproliferative agent-13
CAS:<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>Fórmula:C20H18N2O6Pureza:99.723%Cor e Forma:SolidPeso molecular:382.37Methiocarb
CAS:<p>Methiocarb is a carbamate insecticide acting as a reversible AChE or ChE inhibitor, inducing oxidative stress in rats.</p>Fórmula:C11H15NO2SPureza:98.49%Cor e Forma:Colorless Crystals Immobilizing Agent For Birds Acaricide And Molluscicide (Epa 1998)Peso molecular:225.31(24S)-MC 976
CAS:<p>(24S)-MC 976 is a derivative of Vitamin D3.</p>Fórmula:C27H42O3Pureza:98%Cor e Forma:SolidPeso molecular:414.62N-Acetylhexosamine kinase (NahK)
CAS:<p>NahK phosphorylates GlcNAc/GalNAc at C1 using ATP to form GlcNAc-1P/GalNAc-1P.</p>Cor e Forma:SolidSHO1122147
<p>SHO1122147 (Compound 7m) disrupts the mitochondrial electron transport chain, demonstrating mitochondrial uncoupling activity (EC50=3.6 μM). It increases the cellular oxygen consumption rate (OCR=69%) and enhances cellular respiration. Additionally, SHO1122147 is orally active and can be utilized in research related to obesity and metabolic dysfunction-associated steatohepatitis (MASH).</p>Fórmula:C17H11ClN4O2Cor e Forma:SolidPeso molecular:338.748MK-8245 Trifluoroacetate
CAS:<p>MK-8245 trifluoroacetate: Potent liver-targeting SCD inhibitor, IC50=1nM (human). Anti-diabetic/anti-dyslipidemic. Selective, with low adverse event exposure.</p>Fórmula:C19H17BrF4N6O6Cor e Forma:SolidPeso molecular:581.27Tetrachlorocatechol
CAS:<p>Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol.</p>Fórmula:C6H2Cl4O2Pureza:96.68%Cor e Forma:SolidPeso molecular:247.89MK-4074
CAS:<p>MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).</p>Fórmula:C33H31N3O6Cor e Forma:SolidPeso molecular:565.62DSPE-PEG2000-NYZL1
<p>DSPE-PEG2000-NYZL1 is a PEG compound composed of DSPE and NYZL1. NYZL1 has the ability to specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 is suitable for drug delivery applications.</p>Cor e Forma:Odour Solid2-oxo Clopidogrel
CAS:<p>2-oxo Clopidogrel SR-121683 is a metabolite of Clopidogrel,catalyzed by P450 enzyme via CYP3A oxidation, ydrolysis to the active metabolite CAM.antithrombotic.</p>Fórmula:C16H16ClNO3SCor e Forma:SolidPeso molecular:337.822,6-Diphenylpyridine
CAS:<p>2,6-Diphenylpyridine is toxic to MDA-MB-231 cells and has anticancer potential.</p>Fórmula:C17H13NPureza:99.21%Cor e Forma:SolidPeso molecular:231.296β-hydroxy Eplerenone
CAS:<p>6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP</p>Fórmula:C24H30O7Cor e Forma:SolidPeso molecular:430.497Fenbendazole sulfone
CAS:<p>Fenbendazole sulfone is a minor metabolite of fenbendazole, exhibiting inhibitory activity against 7-ethoxycoumarin O-deethylase in rat liver.</p>Fórmula:C15H13N3O4SPureza:98.70%Cor e Forma:SolidPeso molecular:331.35Girentuximab
CAS:<p>Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).</p>Cor e Forma:LiquidPeso molecular:145.55 kDaAcremonidin A
CAS:<p>Acremonidin A, from Purpureocillium lilacinum, is a strong CaM inhibitor binding to hCaM M124C-mBBr with a Kd of 19.40 nM.</p>Fórmula:C33H26O12Cor e Forma:SolidPeso molecular:614.55Chlorothiazide
CAS:<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Cor e Forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72Z-Asp(OBzl)-OH
CAS:<p>Z-Asp(OBzl)-OH (N-Cbz-L-Aspartic acid 4-benzyl ester) is an aspartic acid derivative.</p>Fórmula:C19H19NO6Pureza:98.71%Cor e Forma:SolidPeso molecular:357.36ALT-100 (Human IgG1)
<p>ALT-100 (HumanIgG1) is a human-derived IgG1 monoclonal antibody that targets NAMPT. For its isotype control, please refer to HumanIgG1kappa, Isotype Control.</p>Cor e Forma:Odour Liquid2S,4R-Sacubitril
<p>2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.</p>Fórmula:C25H31NO5Pureza:98%Cor e Forma:SolidPeso molecular:425.52ATP dipotassium
CAS:<p>ATP dipotassium is key for energy storage, metabolism, cellular processes, and as a signaling molecule for immunity and inflammation.</p>Fórmula:C10H14K2N5O13P3Cor e Forma:SolidPeso molecular:583.367-Methylguanosine 5'-diphosphate sodium
CAS:<p>7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, is utilized in the synthesis of mRNA cap analogues[1].</p>Fórmula:C11H16N5NaO11P2Cor e Forma:SolidPeso molecular:479.21TKL-IN-1
<p>TKL-IN-1 (compound 7r) serves as an inhibitor of transketolase (Transketolase) and can be utilized as an herbicide. This compound effectively hampers the growth of Digitaria sanguinalis (Ds) and Amaranthus retroflexus (Ar).</p>Fórmula:C20H12ClN5OS2Cor e Forma:SolidPeso molecular:437.93HIF-PHD-IN-4
<p>HIF-PHD-IN-4 (Compound 13) is an orally active PHD2 inhibitor with an IC50 of 100 nM. At a dose of 2 mg/kg, it effectively enhances G-CSF-induced mobilization of hematopoietic stem cells in mice. HIF-PHD-IN-4 is suitable for research in the oncology field.</p>Cor e Forma:Odour SolidL-Mevalonic acid
CAS:<p>L-Mevalonic acid, a cholesterol precursor, is studied in autoimmune, atherosclerosis, and Alzheimer's research.</p>Fórmula:C6H12O4Pureza:98%Cor e Forma:SolidPeso molecular:148.16Echinocandin B
CAS:<p>Echinocandin B: a cyclic hexapeptide from A. nidulans, inhibits fungal cell wall synthesis by blocking beta-1,3-glucan.</p>Fórmula:C52H81N7O16Cor e Forma:SolidPeso molecular:1060.24Amiquinsin hydrochloride monohydrate
CAS:<p>Amiquinsin hydrochloride monohydrate is a compound known for its antihypertensive activity. It undergoes metabolism in the body, with its primary metabolite being 4-amino-6,7-dimethoxy-3-quinolineol hydrochloride monohydrate.</p>Fórmula:C11H15ClN2O3Cor e Forma:SolidPeso molecular:258.72-Hydroxy atorvastatin lactone
CAS:<p>2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].</p>Fórmula:C33H33FN2O5Cor e Forma:SolidPeso molecular:556.62Catestatin acetate
<p>Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release.</p>Fórmula:C109H177N37O28SPureza:99.28%Cor e Forma:SolidPeso molecular:2485.87SW209049
CAS:<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Fórmula:C25H18N2O4SPureza:99.72%Cor e Forma:SolidPeso molecular:442.49Bevurogant
CAS:<p>Bevurogant is an antagonist of RORγt receptor and can be used in studies about the treatment of chronic inflammatory diseases.</p>Fórmula:C26H28N8O3SPureza:99.32%Cor e Forma:SolidPeso molecular:532.62L-Lysine, sulfite (2:1)
CAS:<p>L-Lysine, sulfite (2:1) is a drug/ therapeutic agent.</p>Fórmula:C6H14N2O2H2O3SCor e Forma:SolidPeso molecular:187.23DSPE-PEG1000-WYRGRL
<p>DSPE-PEG1000-WYRGRL consists of DSPE and a cartilage-targeting peptide (WYRGRL) as a PEG compound. WYRGRL is a type II collagen-targeting peptide that can bind to type II collagen α1. DSPE-PEG1000-WYRGRL is suitable for drug delivery applications.</p>Cor e Forma:Odour SolidHippadine
CAS:<p>Hippadine is isolated from Crinum bulbs and has reproductive effect.</p>Fórmula:C16H9NO3Cor e Forma:SolidPeso molecular:263.25α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid
CAS:<p>α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid was identified as possible dual inhibitors for hLTA4H and hLTC4S enzymes by the computer-aided</p>Fórmula:C23H23NO3Pureza:97.19% - 99.36%Cor e Forma:SoildPeso molecular:361.431-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
CAS:<p>1-Arachidonoyl LPA: phospholipid with arachidonic acid, sn-1, LPA2 receptor binder, EC50 ~10 nM, modulates cytokine secretion, affects cell differentiation.</p>Fórmula:C23H42NO7PCor e Forma:SolidPeso molecular:475.563Lalistat 2
CAS:<p>Lalistat 2: selective lysosomal acid lipase inhibitor, IC50 152 nM, no effect on pancreatic/milk lipase <10 μM.</p>Fórmula:C13H20N4O2SPureza:99.84%Cor e Forma:SolidPeso molecular:296.39L-Arginyl-L-alanine
CAS:<p>L-Arginyl-L-alanine is a dipeptide and acts as a vasodilator derived from vascular smooth muscle. It can elevate the levels of cyclic guanosine monophosphate (cGMP) and nitrite in endothelium-denuded artery rings.</p>Fórmula:C9H19N5O3Cor e Forma:SolidPeso molecular:245.281,4-Dihydropyridine
<p>1,4-Dihydropyridine acts as an antagonist for calcium channels (calcium channel), specifically blocking the L-type calcium channels. This action reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, consequently decreasing cardiac contractility and heart rate, dilating blood vessels, and lowering blood pressure.</p>Fórmula:C12H17NO4Cor e Forma:SolidPeso molecular:239.27Lofacimig
<p>Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.</p>Cor e Forma:Odour LiquidGeranylgeranyl pyrophosphate
CAS:<p>Geranylgeranyl pyrophosphate: a metabolite for protein modification and diterpenoid precursor, used in cancer research.</p>Fórmula:C20H36O7P2Cor e Forma:SolidPeso molecular:450.44CHEMBL1276927
CAS:<p>CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and</p>Fórmula:C21H17N3OPureza:99.86%Cor e Forma:SolidPeso molecular:327.38WAY-311610
CAS:<p>WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.</p>Fórmula:C16H13F3N4O2Pureza:98.01%Cor e Forma:SolidPeso molecular:350.3D-Erythrose 4-phosphate sodium
CAS:<p>D-erythrose 4-sodium phosphate: sodium salt of monosaccharide, made from erythritol via 3 isomerases.</p>Fórmula:C4H8NaO7PPureza:98%Cor e Forma:SolidPeso molecular:222.07DKI5
CAS:<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Fórmula:C8H10N4SPureza:98%Cor e Forma:SoildPeso molecular:194.26Carbazeran citrate
CAS:<p>aldehyde oxidase (AO) substrate</p>Fórmula:C24H32N4O11Pureza:98%Cor e Forma:SolidPeso molecular:552.53Leucine dehydrogenase
CAS:<p>Leucine dehydrogenase from Bacillus spheroides oxidizes/reduces branched-chain amino acids and their keto analogs.</p>Cor e Forma:SolidPDE5-IN-10
<p>PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM,</p>Fórmula:C21H20N4O2Cor e Forma:SolidPeso molecular:360.41(-)-Jasmonoyl-L-isoleucine
CAS:<p>(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile), an enantiomer of (+)-JA-L-Ile [1], is an inactive endogenous hormone.</p>Fórmula:C18H29NO4Cor e Forma:SolidPeso molecular:323.43(1S)-Calcitriol
CAS:<p>(1S)-Calcitriol, a natural 1α,25(OH)2D3 metabolite, regulates VDR actions like keratinocyte growth inhibition.</p>Fórmula:C27H44O3Cor e Forma:SolidPeso molecular:416.646
