Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8595 produtos de "Metabolismo"
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EC1454
CAS:<p>EC1454 is an anti-tumor compound.</p>Fórmula:C65H98N16O34SPureza:98%Cor e Forma:SolidPeso molecular:1679.63α-Glucosidase-IN-38
<p>α-Glucosidase-IN-38 (Compound 11j) is a potent α-glucosidase inhibitor, demonstrating an IC50 of 12.44±0.38 μM, and is significant in the context of Diabetes</p>Pureza:98%Cor e Forma:Odour SolidGanoderenic acid K
CAS:<p>Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.</p>Fórmula:C32H44O9Cor e Forma:SolidPeso molecular:572.69Eurestobart
CAS:<p>Eurestobart is a humanized IgG1κ (IgG1 kappa) monoclonal antibody that specifically targets the enzyme ectonucleoside triphosphate diphosphohydrolase (ENTPDase</p>Pureza:98%Cor e Forma:LiquidFebuxostat amide impurity
CAS:<p>Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1]</p>Fórmula:C16H18N2O4SCor e Forma:SolidPeso molecular:334.39KT-362 free base
CAS:<p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>Fórmula:C22H28N2O3SPureza:99.76%Cor e Forma:SoildPeso molecular:400.53Rovicurt
CAS:<p>Rovicurt is use as a pesticide.</p>Fórmula:C40H45Cl2NO7Pureza:98%Cor e Forma:SolidPeso molecular:722.7Phospholipase D
CAS:<p>PLD is an enzyme in the phospholipase family, found across many life forms, and linked to diseases like diabetes and cancer.</p>Cor e Forma:SolidRORγt inverse agonist 31
<p>RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (</p>Fórmula:C23H15Cl2F3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:555.36Lysylcysteine TFA
<p>Lysylcysteine (L-Lysyl-L-cysteine)TFA is a dipeptide composed of lysine and cysteine.</p>Fórmula:C13H21F6N3O7SCor e Forma:SolidPeso molecular:477.10044Galactosylhydroxylysine
CAS:<p>Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.</p>Fórmula:C12H24N2O8Cor e Forma:SolidPeso molecular:324.33Thalifendine chloride
CAS:<p>Thalifendine chloride is a metabolite of berberine,the methoxy group at the C-10 position undergoes demethylation by CYP51. cytotoxicity against P-388 cells.</p>Fórmula:C19H16ClNO4Cor e Forma:SolidPeso molecular:357.79Ophiobolin A
CAS:<p>Ophiobolin A: Fungal metabolite, phytotoxin, inhibits calmodulin-activated phosphodiesterase (IC50: 9μM), with antimicrobial and anticancer properties.</p>Fórmula:C25H36O4Pureza:98%Cor e Forma:SolidPeso molecular:400.5594-hydroxy Hexenal
CAS:<p>4-Hydroxy hexenal (4-HHE) are toxic aldehydes that are enriched in flavored gravies and cooking oils with storage time and elevated temperatures.</p>Fórmula:C6H10O2Cor e Forma:SolidPeso molecular:114.14CE(20:5(5Z,8Z,11Z,14Z,17Z)
CAS:<p>CE(20:5(5Z,8Z,11Z,14Z,17Z) is an endogenous metabolite.</p>Fórmula:C47H74O2Pureza:98%Cor e Forma:SolidPeso molecular:671.09XW-032
<p>XW-032 is an apo-IDO1 inhibitor with an IC50 of 21 nM. In the CT26 syngeneic mouse model, XW-032 demonstrates significant in vivo antitumor efficacy with a TGI of 63%, showing potential for cancer research applications.</p>Cor e Forma:Odour Solidm-Tyramine
CAS:<p>m-Tyramine has effects on the adrenergic and dopaminergic receptor.m-Tyramine is an endogenous trace amine neuromodulator.</p>Fórmula:C8H11NOPureza:98%Cor e Forma:SolidPeso molecular:137.18Prolylglutamic acid
CAS:<p>Prolylglutamic acid (H-Pro-Glu-OH) is a proline-glutamic acid dipeptide and endogenous metabolite, targeting the LipY lipase of pathogenic mycobacteria.</p>Fórmula:C10H16N2O5Cor e Forma:SolidPeso molecular:244.24m-PEG8-DSPE
<p>m-PEG8-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>Fórmula:C59H116NO17PPureza:98%Cor e Forma:SolidPeso molecular:1142.52(S)-Salsolidine
CAS:<p>(S)-Salsolidine is a MAO inhibitor with Ki 63μM; its R enantiomer is more effective, Ki 26μM.</p>Fórmula:C12H17NO2Cor e Forma:SolidPeso molecular:207.27N,S-Bis-Fmoc-Glutathione
CAS:<p>N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a K i of 0.32 mM [1].</p>Fórmula:C40H37N3O10SCor e Forma:SolidPeso molecular:751.8Conagenin
CAS:<p>Conagenin is a small molecular immunomodulator isolated by Streptomyces roseosporus.</p>Fórmula:C10H19NO6Pureza:98%Cor e Forma:SolidPeso molecular:249.261-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
CAS:<p>1-Arachidonoyl LPA: phospholipid with arachidonic acid, sn-1, LPA2 receptor binder, EC50 ~10 nM, modulates cytokine secretion, affects cell differentiation.</p>Fórmula:C23H42NO7PCor e Forma:SolidPeso molecular:475.563Ribulose, L-
CAS:<p>Ribulose: key in pentose metabolism, aids L-ribose isomerase study, yeast engineering, and chiral compound research.</p>Fórmula:C5H10O5Cor e Forma:SolidPeso molecular:150.1311-trans Leukotriene C4
CAS:<p>11-trans LTC4 is a C-11 isomer of LTC4, forms slowly on storage, is less common but similarly potent in contractions, pKis: 6.42 (LTC4), 6.58 (11-trans).</p>Fórmula:C30H47N3O9SCor e Forma:SolidPeso molecular:625.78Zaragozic acid D(2)
CAS:<p>Zaragozic acid D(2) inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>Fórmula:C36H50O14Pureza:98%Cor e Forma:SolidPeso molecular:706.7721-Deoxy Cortisone
CAS:<p>21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.</p>Fórmula:C21H28O4Cor e Forma:SolidPeso molecular:344.44Yokonoside
CAS:<p>Yokonoside is a biochemical.</p>Fórmula:C20H21NO11Cor e Forma:SolidPeso molecular:451.384sn-Glycerol 3-phosphate lithium
<p>Lithium sn-glycerol 3-phosphate made by converting dihydroxyacetone phosphate via NADH from glycolysis.</p>Cor e Forma:SolidTianeptine Metabolite MC5 sodium
CAS:<p>Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through β-oxidation, exhibits selective G protein activation</p>Fórmula:C19H20ClN2O4S·NaCor e Forma:SolidPeso molecular:430.88Sapropterin free base
CAS:<p>Sapropterin aids in amino acid breakdown and neurotransmitter synthesis, including dopamine and serotonin, and supports nitric oxide production.</p>Fórmula:C9H15N5O3Pureza:98%Cor e Forma:SolidPeso molecular:241.25γ-Glu-Gly TFA
<p>γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid).</p>Cor e Forma:LiquidVildagliptin carboxylic acid metabolite (trifluoroacetate salt)
CAS:<p>Vildagliptin's main human metabolite inhibits DPP-4 (IC50: 477 μM) in Caco-2 cells, formed by cyano group hydrolysis.</p>Fórmula:C19H27F3N2O6Cor e Forma:SolidPeso molecular:436.428SY-640
CAS:<p>SY-640, an acetamide derivative, strongly protects the liver and lessens Propionibacterium acnes and lipopolysaccharide-induced damage in mice.</p>Fórmula:C11H13NO3Pureza:99.51% - 99.66%Cor e Forma:SolidPeso molecular:207.23Ascorbate oxidase
CAS:<p>Ascorbate oxidase, a REDOX enzyme, catalyzes ascorbic acid and oxygen to dehydroascorbic acid, regulating the extracellular matrix.</p>Cor e Forma:SolidWH-15
CAS:<p>WH-15: fluorogenic reporter for PLC-γ1, PLC-δ1, PLC-β2 with Km values of 49; 30, 86.1 µM. Cleaves to fluorescent 6-aminoquinoline for live cell imaging.</p>Fórmula:C31H43N2O18P3Cor e Forma:SolidPeso molecular:824.6Hydroxy desmethyl Bosentan
CAS:<p>Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver.</p>Fórmula:C26H27N5O7SPureza:98%Cor e Forma:SolidPeso molecular:553.59PROTAC MAGL degrader-1
<p>PROTACMAGLdegrader-1 is an orally active PROTAC agent that simultaneously targets both monoacylglycerol lipase (MAGL) and the E3 ubiquitin ligase MDM2. It functions by degrading MAGL and inhibiting the interaction between MDM2 and p53. Additionally, PROTACMAGLdegrader-1 has partial blood-brain barrier (BBB) penetration and can induce apoptosis in glioblastoma stem cells (GSC).</p>Cor e Forma:Odour Solid8-Isoprostaglandin F2α
CAS:<p>8-Isoprostaglandin F2α is a natural product for research related to life sciences. The catalog number is T37164 and the CAS number is 27415-26-5.</p>Fórmula:C20H34O5Cor e Forma:SolidPeso molecular:354.48Glycyllysine
CAS:<p>Glycyllysine is a dipeptide. It can be used to study the interactions of the lysine side chain with copper in Glycyl-L-lysine-copper(II) complex.</p>Fórmula:C8H17N3O3Cor e Forma:SolidPeso molecular:203.24L-739750 2HCl
<p>L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.</p>Fórmula:C23H41Cl2N3O6S2Pureza:98.69% - 99.16%Cor e Forma:SoildPeso molecular:590.62Sirtuin modulator 2
CAS:<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>Fórmula:C19H15N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:349.41N-Lactoyl-Phenylalanine
CAS:<p>N-Lactoyl-Phenylalanine (Lac-Phe) is a peptide coupling of lactic acid and phenylalanine that can be used in the study of obesity and metabolic off diseases.</p>Fórmula:C12H15NO4Pureza:98.95%Cor e Forma:SolidPeso molecular:237.25α-Hydroxyglutaric Acid Lithium
<p>α-Hydroxyglutaric Acid Lithium is an α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase inhibitor of ATP synthase.</p>Fórmula:C5H6Li2O5Pureza:≥98%Cor e Forma:SoildPeso molecular:159.98BMT-124110 Formate
<p>BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase</p>Fórmula:C22H20N2O2Pureza:99.52%Cor e Forma:SoildPeso molecular:344.41D-Sedoheptulose-7-phosphate (barium salt)
CAS:<p>D-Sedoheptulose-7-phosphate: Key in pentose phosphate path, carbon fixation, and compound biosynthesis.</p>Fórmula:C7H17BaO10PCor e Forma:SolidPeso molecular:429.504DSPE-PEG2000-ESBP
<p>DSPE-PEG2000-ESBP is a PEGylated compound composed of DSPE and E-selectin binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Cor e Forma:Odour SolidPROTAC SGK3 degrader-1
CAS:<p>PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligands to VH032 VHL to induce endogenous SGK3 degradation.</p>Fórmula:C57H73FN10O11S2Pureza:98%Cor e Forma:SolidPeso molecular:1157.38SDUY816
<p>SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.</p>Fórmula:C18H16IN3O3Cor e Forma:SolidPeso molecular:449.24AH078
<p>AH078 (compound 37) is a selective PROTAC degrader targeting CK1δ and CK1ε with low selectivity for CK1α. AH078 consists of a PROTAC linker (black part) Monomethyl octanoate, a target protein ligand (red part) CK1δ/CK1ε ligand-1, and an E3 ligase ligand (blue part) E3 Ligase Ligand 58. The E3 ligase ligand combined with the linker forms the conjugate E3 Ligase Ligand-linker Conjugate 163.</p>Fórmula:C51H60F2N10O5SCor e Forma:SolidPeso molecular:963.15
