Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8595 produtos de "Metabolismo"
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Revizinone
CAS:<p>Revizinone is a novel selective phosphodiesterase inhibitor with IC50 values on this enzyme to 0.036 microM.</p>Fórmula:C26H29N5O3Pureza:98%Cor e Forma:SolidPeso molecular:459.54Carboxylesterase
CAS:<p>CESs are enzymes in mammalian liver hydrolyzing esters and other substrates in biochemical studies.</p>Cor e Forma:SolidSHP2-IN-37
<p>SHP2-IN-37 (compound C5) is a potent allosteric inhibitor selective for SHP2, with an IC50 of 0.023 μM. It exhibits antiproliferative effects on KYSE-520 and MV-411 cells, with IC50 values of 6.97 μM and 0.67 μM, respectively.</p>Fórmula:C19H22Cl2N4O2SCor e Forma:SolidPeso molecular:440.08405Enniatin A
CAS:<p>Enniatin A, a Fusarium toxin, blocks rat liver ACAT with 22 μM IC50.</p>Fórmula:C36H63N3O9Pureza:98%Cor e Forma:SolidPeso molecular:681.9GGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Fórmula:C14H26Cl2N6O5Cor e Forma:SolidPeso molecular:428.13417α-Glucosidase-IN-76
<p>α-Glucosidase-IN-76 (Compound 4r) is an inhibitor of α-glucosidase, with an IC50 of 5.44 μM. It can clear ABTS+ free radicals, with a TEAC value of 0.49. Additionally, α-Glucosidase-IN-76 inhibits the proliferation of T24 bladder cancer cells, with an IC50 of 1.74 μM.</p>Fórmula:C21H24N4O10Cor e Forma:SolidPeso molecular:492.44(Rac)-Mono(3,5,5-trimethylhexyl) phthalate
CAS:<p>(Rac)-Mono(3,5,5-trimethylhexyl) phthalate: a key metabolite of phthalate plasticizers with immune-suppressing effects.</p>Fórmula:C17H24O4Cor e Forma:SolidPeso molecular:292.37D-Ribose 5-phosphate
CAS:<p>Ribose 5-phosphate: Intermediate in oxidative PPP, final in non-oxidative PPP, used for nucleotide and nucleic acid synthesis.</p>Fórmula:C5H11O8PPureza:98%Cor e Forma:SolidPeso molecular:230.11Acesulfame
CAS:<p>Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.</p>Fórmula:C4H5NO4SCor e Forma:SolidPeso molecular:163.155(S)-HETE
CAS:<p>5(S)-HETE, an endogenous metabolite found in the blood, is utilized in researching Rheumatoid Arthritis, Rhinitis, and Asthma [1] [2].</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.47Isodihydroauroglaucin
CAS:<p>Isodihydroauroglaucin is a useful organic compound for research related to life sciences. The catalog number is T124274 and the CAS number is 74886-31-0.</p>Fórmula:C19H24O3Cor e Forma:SolidPeso molecular:300.398Saccharopine
CAS:<p>L-Saccharopine is a product of the breakdown of essential amino acid Lysine.</p>Fórmula:C11H20N2O6Cor e Forma:SolidPeso molecular:276.29PF-03049423
CAS:<p>PF-03049423: potent, selective PDE-5A inhibitor, IC50 ~0.2 nM, for rat/human thrombomodulin; used in ischemic stroke research.</p>Fórmula:C24H32N6O4Pureza:99.89% - 99.93%Cor e Forma:SolidPeso molecular:468.55Nicotinic Acid Adenine Dinucleotide
CAS:<p>Nicotinic Acid Adenine Dinucleotide is a precursor of NAD (Nicotinamide adenine dinucleotide) and a substrate for glutamine-dependent NAD+ synthase</p>Fórmula:C21H26N6O15P2Cor e Forma:SoildPeso molecular:664.41Aminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Fórmula:C12H16F2N2O4SCor e Forma:SolidPeso molecular:322.07988γ-Globulins from human blood
CAS:<p>γ-Globulins, a protein fraction found in human blood, comprise a class of proteins with potent antibody activity that safeguards against bacterial and viral</p>Cor e Forma:Solid5,6-Dihydro-2H-pyran-2-one
CAS:<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Fórmula:C5H6O2Cor e Forma:SolidPeso molecular:98.1O-Desmethyl apixaban
CAS:<p>O-Desmethyl apixaban is a metabolite of Apixaban, a selective Factor Xa inhibitor with Ki of 0.08 nM in humans.</p>Fórmula:C24H23N5O4Pureza:98%Cor e Forma:SolidPeso molecular:445.47Metrizamide
CAS:<p>Metrizamide is a nonionic radiopaque contrast agent.</p>Fórmula:C18H22I3N3O8Cor e Forma:SolidPeso molecular:789.1DSPE-PEG2000-EB1
<p>DSPE-PEG2000-EB1 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (EB1). It is utilized for drug delivery.</p>Cor e Forma:Odour SolidMonoisobutyl phthalic acid
CAS:<p>Monoisobutyl phthalic acid is a metabolite of phthalate that is in human semen and in meconium.</p>Fórmula:C12H14O4Pureza:98%Cor e Forma:SolidPeso molecular:222.24TAT-cyclo-CLLFVY
CAS:<p>Blocks HIF-1α/β dimerization, not HIF-2α; suppresses VEGF, CAIX in cancer cells; antiangiogenic in HUVECs (IC50 = 1.3 μM).</p>Fórmula:C111H188N42O24S2Pureza:98%Cor e Forma:SolidPeso molecular:2559.1Fumiquinazoline D
CAS:<p>Fumiquinazoline D, from A. fumigatus, inhibits Gram-positive/negative bacteria (MIC 8-16 μg/ml) and F. solani, C. albicans (MIC 32, 64 μg/ml).</p>Fórmula:C24H21N5O4Cor e Forma:SolidPeso molecular:443.463Oxodipine
CAS:<p>Oxodipine blocks rabbit aortic contraction and weakens rat cardiac force; reduces Ca currents in myocytes; side effects: mouse constipation, dog gum swelling.</p>Fórmula:C19H21NO6Pureza:99.24%Cor e Forma:SolidPeso molecular:359.37TP0472993
CAS:<p>CYP4A11/CYP4F2-IN-2: Potent oral inhibitor of CYP4A11 & CYP4F2 (IC50: 140 & 40 nM), potential kidney disease treatment.</p>Fórmula:C16H20N4O2Pureza:98.47%Cor e Forma:SoildPeso molecular:300.367-Hydroxyneolamellarin A
CAS:<p>7-Hydroxyneolamellarin A, from Dendrilla nigra, inhibits HIF-1α and VEGF in cancer research.</p>Fórmula:C24H19NO5Cor e Forma:SolidPeso molecular:401.41Casein kinase 1δ-IN-9
CAS:<p>Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.</p>Fórmula:C15H12ClN3Pureza:99.93%Cor e Forma:SolidPeso molecular:269.73DSPE-PEG1000-NGR
<p>DSPE-PEG1000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide has the capability to target the CD13 antigen present in tumor vasculature. DSPE-PEG1000-NGR can be utilized for drug delivery.</p>Cor e Forma:Odour SolidIDO1/TDO-IN-8
<p>IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.</p>Fórmula:C17H14N2SCor e Forma:SolidPeso molecular:278.37Lysylcysteine TFA
<p>Lysylcysteine (L-Lysyl-L-cysteine)TFA is a dipeptide composed of lysine and cysteine.</p>Fórmula:C13H21F6N3O7SCor e Forma:SolidPeso molecular:477.10044Cryptosporioptide A
CAS:<p>Cryptosporioptide A (Compound 3), a protein tyrosine phosphatase inhibitor, originates from the insect-parasitic fungus Cordyceps gracilioides.</p>Fórmula:C18H17NO10Pureza:98%Cor e Forma:SolidPeso molecular:407.33IGUANA-1 free base
CAS:<p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>Fórmula:C26H24ClN3O2Cor e Forma:SolidPeso molecular:445.94Butyrolactone II
CAS:<p>Butyrolactone II is a useful organic compound for research related to life sciences. The catalog number is T124034 and the CAS number is 87414-44-6.</p>Fórmula:C19H16O7Cor e Forma:SolidPeso molecular:356.33Azide-phenylalanine hydrochloride
CAS:<p>UAA crosslinker 2 is a phenylalanine derivative.</p>Fórmula:C9H11ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:242.66Morin 3-O-β-D-glucopyranoside
CAS:<p>Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties.</p>Fórmula:C21H20O12Cor e Forma:SolidPeso molecular:464.38BIRM 271
CAS:<p>BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.</p>Fórmula:C21H25N3OPureza:99.64%Cor e Forma:SoildPeso molecular:335.44NoxA1ds
CAS:<p>Selective NOX1 inhibitor; IC50 at 20 nM; spares NOX2/4/5 and xanthine oxidase; reduces HT-29 O2- and hinders VEGF-induced cell migration.</p>Fórmula:C50H88N14O15Pureza:98%Cor e Forma:SolidPeso molecular:1125.33Casein Kinase 2 Substrate Peptide
CAS:<p>CK2 Substrate Peptide, C-terminus linked to EDANS, used for CK2 activity assays.</p>Fórmula:C45H73N19O24Cor e Forma:SolidPeso molecular:1264.17α-2,8-Sialyltransferase (CstII)
CAS:<p>CstII (ST8Sia VI), an alpha-2,8-sialyltransferase, catalyzes α2,8 oligo/polysialic acid chain elongation. Used in biochemical research.</p>Cor e Forma:SolidDSPE-PEG5000-KAA
<p>DSPE-PEG5000-KAA is a PEG compound composed of DSPE and the CKAAKNK (KAA) peptide. The CKAAKNK peptide specifically targets the tumor vasculature of RIP-Tag2 transgenic mice. DSPE-PEG5000-KAA can be utilized for drug delivery purposes.</p>Cor e Forma:Odour SolidPDE4-IN-4
CAS:<p>PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment of</p>Fórmula:C36H37Cl2N3O7SCor e Forma:SolidPeso molecular:726.6711R-CaN-AID
CAS:<p>11R-CaN-AID is a potent, cell-permeant inhibitor of calcineurin [1] [2].</p>Fórmula:C135H248N70O34S2Cor e Forma:SolidPeso molecular:3459.99α-D-Glucose-1-phosphate disodium hydrate
CAS:<p>α-D-Glucose-1-phosphate disodium hydrate serves multiple roles in medical and biochemical applications, including as a precursor in the synthesis of glucuronic</p>Fórmula:C6H15Na2O11PCor e Forma:SolidPeso molecular:340.13LOX-IN-5
CAS:<p>LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.</p>Fórmula:C21H25FN4O2SCor e Forma:SolidPeso molecular:416.51TEI-9648
CAS:<p>TEI-9648: Potent, specific VDR antagonist, blocks 1α,25(OH)2D3 effects, may aid bone metabolism study.</p>Fórmula:C27H38O4Cor e Forma:SolidPeso molecular:426.597Maltodextrin, dextrose equivalent 16.5-19.5
CAS:<p>Maltodextrin (DE 16.5-19.5) is an inactive pharma excipient that enhances drug stability, solubility, and processing.</p>Fórmula:(C6H10O5)n·xH2OCor e Forma:SolidRisperidone E-oxime
CAS:<p>Risperidone E-oxime: Risperidone impurity, 5-HT2 & dopamine D2 blocker (Ki: 4.8, 5.9 nM), P-Glycoprotein inhibitor.</p>Fórmula:C23H28F2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:430.49Isomer-Turosteride
<p>Isomer-Turosteride, a novel 5α-reductase inhibitor, reduces prostate DHT and has anticancer properties without raising T levels.</p>Fórmula:C27H45N3O3Pureza:98.94%Cor e Forma:SolidPeso molecular:459.67Mycestericin G
CAS:<p>Mycestericin G, a sphingosine-like fungal metabolite, demonstrates immunosuppressive activity [1].</p>Fórmula:C21H41NO5Cor e Forma:SolidPeso molecular:387.555-(3',4'-Dihydroxyphenyl)-γ-valerolactone
CAS:<p>5-(3',4'-Dihydroxyphenyl)-γ-valerolactone is a metabolic byproduct of gut microbiota processing of (-)-Epicatechin. [5-(3',4'-Dihydroxyphenyl)-γ-valerolactone] exhibits antioxidant properties.</p>Fórmula:C11H12O4Cor e Forma:SolidPeso molecular:208.21
